| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
glomerular filtration rate to kidney weight ratio |
controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (150 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (170-175 mmHg) (for 0.3 hours) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
glomerular filtration trait |
male |
70.0 days
| 8 |
|
0.78 |
ml/min/g |
0.07 |
0.2 |
liquid scintillation counting |
|
0 |
|
|
|
64938 |
272 |
| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
glomerular filtration rate to kidney weight ratio |
controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
glomerular filtration trait |
male |
70.0 days
| 8 |
|
0.56 |
ml/min/g |
0.07 |
0.2 |
liquid scintillation counting |
|
0 |
|
|
|
64943 |
272 |
| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
urine fractional sodium excretion |
controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
urine sodium amount |
male |
70.0 days
| 8 |
|
1.29 |
% |
0.34 |
0.96 |
flame atomic emission spectrometry |
|
1200 |
|
|
Fractional |
64969 |
272 |
| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
mean arterial blood pressure |
controlled sodium content diet (8 %) (for 14 days) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
arterial blood pressure trait |
male |
80.0 days
| 9 |
serial mean |
145.0 |
mmHg |
|
|
radiotelemetry |
femoral artery |
|
|
connected to solid-state transducer (Argon Medical Technologies, Athens, TX) |
5 hr recording session - 1 min. averages, averaged over 4 days |
64827 |
272 |
| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
mean arterial blood pressure |
controlled sodium content diet (8 %) (for 21 days) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
arterial blood pressure trait |
male |
86.0 days
| 8 |
serial mean |
150.0 |
mmHg |
|
|
radiotelemetry |
femoral artery |
0 |
|
connected to solid-state transducer (Argon Medical Technologies, Athens, TX) |
5 hr recording session - 1 min. averages, averaged over 4 days |
12655 |
272 |
| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
urine fractional sodium excretion |
controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (150 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (170-175 mmHg) (for 0.3 hours) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
urine sodium amount |
male |
70.0 days
| 8 |
|
7.84 |
% |
0.82 |
2.32 |
flame atomic emission spectrometry |
|
1200 |
|
|
Fractional |
64970 |
272 |
| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
mean arterial blood pressure |
controlled sodium content diet (8 %) (between 21 and 25 days) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
arterial blood pressure trait |
male |
82.0 days-86.0 days |
32 |
serial mean |
159.0 |
mmHg |
|
|
vascular fluid filled catheter |
femoral artery |
345600 |
|
connected to solid-state transducer (Argon Medical Technologies, Athens, TX) |
5 hr recording session - 1 min. averages, averaged over 4 days |
12618 |
272 |
| SS.LEW-(D5Rat130-D5Rat31)/JrMcwi |
renal arterial blood flow rate |
controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) |
Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. |
renal blood flow trait |
male |
70.0 days
| 8 |
|
6.6 |
ml/min/g |
0.5 |
1.41 |
ultrasonic flowmeter |
|
1200 |
|
|
|
64953 |
272 |