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Ontology Browser

Term:
increased mammary duct terminal end bud number (MP:0031175)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
decreased mammary duct terminal end bud number +   
increased mammary duct terminal end bud number 
greater number of unique club-shaped epithelial structures formed at the tip of the mammary duct at the onset of puberty (approximately 3 weeks of age in mouse) under the action of circulating hormones; normally, TEBs proliferate, ramify, and actively invade the fad pad to allow the formation of a complex branching structure; this process of branching morphogenesis concludes at about 10-12 weeks of age in mouse, when TEBs have traversed the length of the fat pad and a fully developed ductal tree has formed; increase in TEBs is often associated with increased ductal outgrowth and branching morphogenesis

Synonyms
Exact Synonyms: increased mammary duct TEB number
Definition Sources: PMID:16280048, PMID:16916375, PMID:18296651

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