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phosphatase activity +     
10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity  
2-carboxy-D-arabinitol-1-phosphatase activity 
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity  
2-phosphosulfolactate phosphatase activity 
3',5'-nucleotide bisphosphate phosphatase activity  
3-deoxy-manno-octulosonate-8-phosphatase activity 
3-phosphoglycerate phosphatase activity 
3-phytase activity  
4-phytase activity  
5'-deoxynucleotidase activity  
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity 
5-phytase activity 
acid phosphatase activity  
acireductone synthase activity  
Catalysis of the reactions:5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate.
ADP-phosphoglycerate phosphatase activity 
alkaline phosphatase activity  
alkylacetylglycerophosphatase activity 
alpha-ribazole phosphatase activity 
bisphosphoglycerate 3-phosphatase activity  
carbohydrate phosphatase activity +   
D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity 
deoxynucleotide 3'-phosphatase activity 
dihydrosphingosine-1-phosphate phosphatase activity  
dolichyl-phosphatase activity 
ecdysteroid-phosphate phosphatase activity 
FMN hydrolase activity 
fructose-1-phosphatase activity  
glucosylglycerol 3-phosphatase activity 
glycerol-1-phosphatase activity  
glycerol-2-phosphatase activity 
glycerol-3-phosphatase activity  
guanidinodeoxy-scyllo-inositol-4-phosphatase activity 
histidinol-phosphatase activity 
inositol phosphate phosphatase activity +   
L-phosphoserine phosphatase activity  
lipid phosphatase activity +   
lysophosphatidic acid phosphatase activity  
mannitol-1-phosphatase activity 
mannosyl-3-phosphoglycerate phosphatase activity 
methylphosphothioglycerate phosphatase activity 
monoterpenyl-diphosphatase activity 
N-acylneuraminate-9-phosphatase activity  
NADP phosphatase activity  
NADPH phosphatase activity  
nucleotidase activity +   
phosphatidylglycerophosphatase activity  
phosphatidylinositol phosphate phosphatase activity +   
phosphocholine phosphatase activity  
phosphoenolpyruvate phosphatase activity 
phosphoethanolamine phosphatase activity  
phosphoglycerate phosphatase activity 
phosphoglycolate phosphatase activity  
phosphoprotein phosphatase activity +   
polynucleotide 3'-phosphatase activity  
polynucleotide 5'-phosphatase activity  
pseudouridine 5'-phosphatase activity  
pyridoxal phosphatase activity  
ribitol-5-phosphatase activity 
sedoheptulose-bisphosphatase activity 
sorbitol-6-phosphatase activity 
streptomycin-6-phosphatase activity 
thiamine phosphate phosphatase activity  

Synonyms
Broad Synonyms: E-1 enolase-phosphatase
Related Synonyms: 5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing) ;   E-1
Xrefs: EC:3.1.3.77 ;   MetaCyc:3.1.3.77-RXN ;   RHEA:21700 ;   reactome:R-HSA-1237129 "Acireductone is created"
Definition Sources: RHEA:21700

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