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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
NuA4 histone acetyltransferase complex  
A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).

Synonyms
Exact Synonyms: TIP60 histone acetylase complex ;   TIP60 histone acetyltransferase complex
Definition Sources: GOC:ecd, PMID:10966108, PMID:14966270

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