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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal skeletal muscle satellite cell proliferation
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Accession:MP:0009410 term browser browse the term
Definition:anomaly in the ability of the elongated, spindle-shaped cells located between the basal lamina and the plasmalemma of a muscle fiber to undergo expansion by cell division, usually triggered by injury or disease; these cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers
Comment:Skeletal muscle satellite cells are not traditionally referred to as myoblasts. They are a heterogeneous population whose division, following activation, contributes to the formation of skeletal muscle fibers and to maintenance of the skeletal muscle satellite cell population.


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  mammalian phenotype 5417
    muscle phenotype 199
      abnormal muscle physiology 124
        abnormal skeletal muscle satellite cell proliferation 0
          decreased skeletal muscle satellite cell proliferation 0
          increased skeletal muscle satellite cell proliferation 0
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  mammalian phenotype 5417
    cellular phenotype 184
      abnormal cell physiology 143
        abnormal cell proliferation 25
          abnormal skeletal muscle satellite cell proliferation 0
            decreased skeletal muscle satellite cell proliferation 0
            increased skeletal muscle satellite cell proliferation 0
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