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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased mammary duct terminal end bud number
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Accession:MP:0031175 term browser browse the term
Definition:greater number of unique club-shaped epithelial structures formed at the tip of the mammary duct at the onset of puberty (approximately 3 weeks of age in mouse) under the action of circulating hormones; normally, TEBs proliferate, ramify, and actively invade the fad pad to allow the formation of a complex branching structure; this process of branching morphogenesis concludes at about 10-12 weeks of age in mouse, when TEBs have traversed the length of the fat pad and a fully developed ductal tree has formed; increase in TEBs is often associated with increased ductal outgrowth and branching morphogenesis
Synonyms:exact_synonym: increased mammary duct TEB number


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Path 1
Term Annotations click to browse term
  mammalian phenotype 16979
    integument phenotype 2836
      abnormal skin adnexa morphology 1639
        abnormal mammary gland morphology 314
          abnormal mammary gland epithelium morphology 104
            abnormal mammary gland duct morphology 89
              abnormal mammary duct terminal end bud morphology 9
                increased mammary duct terminal end bud number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 16979
    endocrine/exocrine gland phenotype 3458
      abnormal gland morphology 3218
        abnormal exocrine gland morphology 1128
          abnormal apocrine gland morphology 314
            abnormal mammary gland morphology 314
              abnormal mammary gland epithelium morphology 104
                abnormal mammary gland duct morphology 89
                  abnormal mammary duct terminal end bud morphology 9
                    increased mammary duct terminal end bud number 0
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