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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased mammary duct terminal end bud number
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Accession:MP:0031175 term browser browse the term
Definition:greater number of unique club-shaped epithelial structures formed at the tip of the mammary duct at the onset of puberty (approximately 3 weeks of age in mouse) under the action of circulating hormones; normally, TEBs proliferate, ramify, and actively invade the fad pad to allow the formation of a complex branching structure; this process of branching morphogenesis concludes at about 10-12 weeks of age in mouse, when TEBs have traversed the length of the fat pad and a fully developed ductal tree has formed; increase in TEBs is often associated with increased ductal outgrowth and branching morphogenesis
Synonyms:exact_synonym: increased mammary duct TEB number

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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    integument phenotype 0
      abnormal skin adnexa morphology 0
        abnormal mammary gland morphology 0
          abnormal mammary gland epithelium morphology 0
            abnormal mammary gland duct morphology 0
              abnormal mammary duct terminal end bud morphology 0
                increased mammary duct terminal end bud number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    endocrine/exocrine gland phenotype 0
      abnormal gland morphology 0
        abnormal exocrine gland morphology 0
          abnormal apocrine gland morphology 0
            abnormal mammary gland morphology 0
              abnormal mammary gland epithelium morphology 0
                abnormal mammary gland duct morphology 0
                  abnormal mammary duct terminal end bud morphology 0
                    increased mammary duct terminal end bud number 0
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