decreased cementoblast number - Ontology Report

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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	decreased cementoblast number	go back to main search page
Accession:	MP:0030552	browse the term
Definition:	fewer than the expected number of the large cuboidal cells differentiated from fibroblasts of the dental follicle (or possibly from Hertwig’s epithelial root sheath cells by epithelial-mesenchymal transformation) that, during formation of cellular cementum, secrete a layer of unmineralized extracellular matrix called cementoid; as cementoid deposition progresses, some cementoblasts become embedded in cementoid matrix and become cementocytes
Synonyms:	exact_synonym:	reduced cementoblast number

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Genes (1)

decreased cementoblast number

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Dmp1

dentin matrix protein 1

NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	17088
skeleton phenotype	3397
abnormal skeleton morphology	3204
abnormal bone structure	1542
abnormal osteoblast morphology	187
abnormal cementoblast morphology	1
abnormal cementoblast number	1
decreased cementoblast number	1
Path 2
Term	Annotations
mammalian phenotype	17088
skeleton phenotype	3397
abnormal skeleton morphology	3204
abnormal axial skeleton morphology	1792
abnormal craniofacial bone morphology	1046
abnormal cranium morphology	1030
abnormal viscerocranium morphology	762
abnormal jaw morphology	690
abnormal dental arch morphology	368
abnormal tooth morphology	367
abnormal tooth hard tissue morphology	74
abnormal cementum morphology	8
abnormal cementum development	3
abnormal cementoblast morphology	1
abnormal cementoblast number	1
decreased cementoblast number	1

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