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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased transitional stage T3 B cell number
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Accession:MP:0010228 term browser browse the term
Definition:reduced number of a type of a transitional stage B cell that expresses surface IgM and IgD, and CD62L; it is an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, and CD62L-positive
Synonyms:exact_synonym: decreased T3 stage B cell number;   decreased transitional three stage B lymphocyte number;   decreased transitional three stage B-cell number;   reduced T3 stage B cell number;   reduced transitional three stage B-cell number;   reduced transitional three stage B-lymphocyte number
 xref: CL:0000960


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5422
    immune system phenotype 519
      abnormal immune system morphology 211
        abnormal immune system cell morphology 150
          abnormal leukopoiesis 16
            abnormal lymphopoiesis 16
              abnormal B cell differentiation 0
                abnormal immature B cell morphology 0
                  abnormal transitional stage B cell morphology 0
                    decreased transitional stage B cell number 0
                      decreased transitional stage T3 B cell number 0
                        absent transitional stage T3 B cells 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5422
    hematopoietic system phenotype 267
      abnormal hematopoietic system morphology/development 247
        abnormal hematopoietic cell morphology 182
          abnormal blood cell morphology 95
            abnormal hemopoiesis 16
              abnormal definitive hematopoiesis 16
                abnormal leukopoiesis 16
                  abnormal lymphopoiesis 16
                    abnormal B cell differentiation 0
                      abnormal immature B cell morphology 0
                        abnormal immature B cell number 0
                          decreased immature B cell number 0
                            decreased transitional stage B cell number 0
                              decreased transitional stage T3 B cell number 0
                                absent transitional stage T3 B cells 0
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