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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Chorangioma
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Accession:HP:0100883 term browser browse the term
Definition:Hamartoma-like growth in the placenta consisting of blood vessels.
Comment:Chorioangiomas (also known as placental hemangiomas) are benign hamartomatous growth of the placenta comprising vascular tissue. The classification is controversial due to its pathologic features and clinical implications. Some authors call placental hemangiomas as true nontrophoblastic neoplastic tissues. As this abnormal vascular growth seems like the native placental tissue and it does not metastasize, some authors call it just as placental hamartoma. The general incidence is approximately 0.6 percent. Giant chorioangiomas with a diameter over 5 cm are very rare, with an incidence of one in 16-50 thousand pregnancies. Small tumors do not cause any adverse outcomes and they are asymptomatic. In contrast, tumors larger than 5 cm may lead to several complications.
Synonyms:exact_synonym: Placental hamartoma
 xref: SNOMEDCT_US:2099007;   SNOMEDCT_US:237268002;   SNOMEDCT_US:699948001;   UMLS:C0677608


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  Human phenotype 74032
    Phenotypic abnormality 73727
      Abnormality of prenatal development or birth 1206
        Abnormalities of placenta or umbilical cord 128
          Abnormal placenta morphology 48
            Chorangioma 0
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