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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Crystalluria
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Accession:HP:0020074 term browser browse the term
Definition:The presence of crystals in the urine.
Comment:Crystalluria is a marker of urine supersaturation with substances deriving from metabolic disorders, inherited diseases or drugs. The investigation of crystalluria must be done according to a protocol which includes the delivery to the laboratory of a proper urine sample, the use of a microscope equipped with polarized light, the accurate knowledge of urine pH, and a comprehensive examination of the crystals, which is based on their identification, quantification and size measurement. For unusual crystals, infrared spectroscopy may also be needed. The main urinary crystalline categories include: calcium oxalates, calcium phosphates, uric acids and urates, struvite, aminoacids (cystine), purines (2,8-dihydroxyadenine and xanthine) and drugs (e.g. sulfamethoxazole, amoxycillin, ceftriaxone, atazanavir).


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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of metabolism/homeostasis 0
        Abnormality of urine homeostasis 0
          Crystalluria 0
            2,8-dihydroxyadenine crystalluria 0
            Calcium carbonate crystalluria 0
            Calcium oxalate crystalluria 0
            Calcium phosphate crystalluria 0
            Cholesterol crystalluria 0
            Cystine crystalluria 0
            Leucine crystalluria 0
            Magnesium ammonium phosphate crystalluria 0
            Medication crystalluria 0
            Orotic acid crystalluria 0
            Uric acid crystalluria 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the genitourinary system 0
        Abnormality of the urinary system 0
          Abnormality of the urinary system physiology 0
            Abnormality of urine homeostasis 0
              Crystalluria 0
                2,8-dihydroxyadenine crystalluria 0
                Calcium carbonate crystalluria 0
                Calcium oxalate crystalluria 0
                Calcium phosphate crystalluria 0
                Cholesterol crystalluria 0
                Cystine crystalluria 0
                Leucine crystalluria 0
                Magnesium ammonium phosphate crystalluria 0
                Medication crystalluria 0
                Orotic acid crystalluria 0
                Uric acid crystalluria 0
paths to the root