Lewis x epitope biosynthetic process - Ontology Report

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Term:	Lewis x epitope biosynthetic process	go back to main search page
Accession:	GO:0106402	browse the term
Definition:	The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide.
Synonyms:	related_synonym:	sLeX biosynthetic process; sialyl-Lewis X biosynthetic process

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Genes (2)

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fut4

fucosyltransferase 4

involved_in

GO_REF:0000024
(PMID:29593094)

GO_REF:0000024

NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682

fucosyltransferase 9

involved_in

GO_REF:0000024
(PMID:29593094), (PMID:37202521)
(MGI:7539442|PMID:22645129)

GO_REF:0000024 MGI:7539442

NCBI chr 5:39,351,815...39,565,256
Ensembl chr 5:39,351,819...39,565,130

Term paths to the root

Path 1
Term	Annotations
biological_process	20115
metabolic process	12289
carbohydrate derivative metabolic process	1127
carbohydrate derivative biosynthetic process	648
Lewis x epitope biosynthetic process	2

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