Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:hydroxymethylglutaryl-CoA reductase (NADH) activity
go back to main search page
Accession:GO:0140643 term browser browse the term
Definition:Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD+ = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.
Comment:Note that this activity is not present in eukaryotes, see PMID:29224355.
Synonyms:broad_synonym: 3-hydroxy-3-methylglutaryl coenzyme A reductase activity;   HMG-CoA reductase activity;   beta-hydroxy-beta-methylglutaryl CoA-reductase activity;   beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity;   hydroxymethylglutaryl coenzyme A reductase activity
 xref: EC:1.1.1.88;   KEGG_REACTION:R02081;   MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN;   RHEA:14833
 never_in_taxon: NCBITaxon:2759 ! Eukaryota

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17128
    catalytic activity 5252
      oxidoreductase activity 692
        oxidoreductase activity, acting on CH-OH group of donors 117
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 109
            hydroxymethylglutaryl-CoA reductase (NADH) activity 0
paths to the root