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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:gastroesophageal reflux disease
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Accession:EFO:0003948 term browser browse the term
Definition:A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa. Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
Synonyms:exact_synonym: Esophageal Reflux;   GASTROESOPHAGEAL REFLUX DIS;   GERD;   GERD - gastro-esophageal reflux disease;   Gastresophageal reflux;   Gastro Esophageal Reflux;   Gastro oesophageal Reflux;   Gastroesophageal Reflux;   acid reflux;   reflux
 related_synonym: gastroesophageal reflux, paediatric;   gastroesophageal reflux, pediatric;   ger
 xref: DOID:8534;   HP:0002020;   ICD10:K21;   ICD9:530.81;   MEDGEN:6553;   MESH:D005764;   MIM:109350;   MONDO:0007186;   MP:0003286;   MedDRA:10038262;   MedDRA:10066874;   NCI:C26781;   SCTID:235595009;   SNOMEDCT:235595009;   UMLS:C0017168
 external_ontology: has_disease_location EFO:UBERON:0000945;   has_disease_location EFO:UBERON:0001043


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Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          genetic disorder 0
            gastroesophageal reflux disease 0
              Laryngopharyngeal Reflux 0
              duodenogastric reflux 0
Path 2
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          digestive system disease 0
            gastrointestinal disease 0
              stomach disease 0
                gastroesophageal reflux disease 0
                  Laryngopharyngeal Reflux 0
                  duodenogastric reflux 0
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