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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:benign prostatic hyperplasia
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Accession:EFO:0000284 term browser browse the term
Definition:A disease caused by hyperplastic process of non-transformed prostatic cells. A non-cancerous nodular enlargement of the prostate gland. It is characterized by the presence of epithelial cell nodules, and stromal nodules containing fibrous and smooth muscle elements. It is the most common urologic disorder in men, causing blockage of urine flow. A non-cancerous nodular enlargement of the prostate gland. It is characterized by the presence of epithelial cell nodules, and stromal nodules containing fibrous and smooth muscle elements. It is the most common urologic disorder in men, causing blockage of urine flow. Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
Synonyms:exact_synonym: Adenofibromatous hypertrophy of prostate;   Adenofibromatous hypertrophy of prostate, NOS;   Adenomyomatous hyperplasia of prostate gland;   BEP - Benign enlargement of prostate;   BPH - Benign prostatic hypertrophy;   Benign Hyperplasia of Prostate;   Benign Hyperplasia of the Prostate;   Benign Prostate Hyperplasia;   Benign Prostatic Hyperplasia - BPH;   Benign adenoma of prostate;   Benign enlargement of prostate;   Benign enlargement of prostate, NOS;   Benign fibroma of prostate;   Benign myoma of prostate;   Benign prostatic hyperplasia (disorder);   Benign prostatic hyperplasia, NOS;   Enlarged prostate - benign;   Fibromuscular hyperplasia of prostate gland;   Glandular, stromal AND/OR muscular hyperplasia of prostate gland;   Glandular, stromal and muscular hyperplasia of prostate gland;   Hyperplasia of prostate;   Hyperplasia of prostate (disorder);   Hyperplasia of prostate, NOS;   Hypertrophy (benign) of prostate;   Lobular hyperplasia of prostate gland;   Nodular hyperplasia of prostate gland;   Prostatauxe;   Prostatic Adenoma;   Prostatic Adenomas;   Prostatic Hyperplasia;   Prostatic area hypertrophy;   Prostatic hyper -benign;   Prostatic hypertrophy;   benign hypertrophy of prostate NOS;   benign prostatic Hypertrophy;   benign prostatic hyperplasia (disease)
 broad_synonym: prostate hypertrophy
 related_synonym: BPH
 xref: DOID:11132;   DOID:2883;   HP:0008711;   ICD10:N40;   ICD9:600;   ICD9:600.0;   ICD9:600.20;   MEDGEN:312369;   MESH:D011470;   MIM:600082;   MONDO:0010811;   MedDRA:10004446;   NCI:C2897;   SCTID:266569009;   SNOMEDCT:266569009;   UMLS:C1704272;   VT:0010571
 external_ontology: has_disease_location EFO:UBERON:0002367


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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          cancer or benign tumor 0
            hyperplasia 0
              benign prostatic hyperplasia 0
Path 2
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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          reproductive system disease 0
            male reproductive system disease 0
              prostate disease 0
                benign prostatic hyperplasia 0
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