chronic lymphocytic leukemia - Ontology Report

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Term:	chronic lymphocytic leukemia	go back to main search page
Accession:	EFO:0000095	browse the term
Definition:	B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma, and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia. The clinical course is extremely heterogeneous with survival ranging from a few months to several decades.
Synonyms:	exact_synonym:	B cell CLL; B cell chronic lymphocytic leukaemia; B cell chronic lymphocytic leukemia; B cell lymphocytic leukaemia; B cell lymphocytic leukemia; B-CLL; B-cell chronic lymphogenous leukaemia; B-cell chronic lymphogenous leukemia; B-cell chronic lymphoid leukaemia; B-cell chronic lymphoid leukemia; BCLL; CLL; chronic lymphatic leukaemia; chronic lymphocytic leukaemia; chronic lymphocytic leukaemia (CLL); chronic lymphocytic leukemia (CLL); chronic lymphogenous leukaemia; chronic lymphogenous leukemia; hematopoeitic - chronic lymphocytic leukaemia (CLL); hematopoeitic - chronic lymphocytic leukemia (CLL); lymphoplasmacytic leukaemia; lymphoplasmacytic leukemia
	related_synonym:	leukemia, chronic lymphatic; small lymphocytic lymphoma
	xref:	DOID:1040; GARD:6104; HP:0005550; ICD10:C91.1; ICD10:C91.10; ICD9:204.1; MEDGEN:44120; MESH:D015451; MIM:151400; MONDO:0004948; MedDRA:10008958; NCI:C3163; NORD:971; ORDO:67038; UMLS:C0023434; UMLS:C0855095; VT:0010898
	external_ontology:	has_modifier EFO:HP:0011010

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Path 1
Term	Annotations
experimental factor	0
material property	0
disposition	0
disease	0
chronic disease	0
chronic lymphocytic leukemia	0
hairy cell leukemia +	0
Path 2
Term	Annotations
experimental factor	0
material property	0
disposition	0
disease	0
cancer or benign tumor	0
neoplastic disease or syndrome	0
neoplasm	0
hematopoietic and lymphoid system neoplasm	0
hematopoietic and lymphoid cell neoplasm	0
lymphoid neoplasm	0
lymphoma	0
non-Hodgkins lymphoma	0
B-cell non-Hodgkins lymphoma	0
indolent B-cell non-Hodgkin lymphoma	0
chronic lymphocytic leukemia	0
hairy cell leukemia +	0

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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS