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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:central nervous system germ cell tumor
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Accession:DOID:4439 term browser browse the term
Definition:A central nervous system cancer that is characterized by tumors near the pineal gland, the pituitary gland and the tissue just above it, develops from mismigrational pluripotent embryonic cells that remain in the brain after birth, has_material_basis_in abnormally proliferating cells derives_from germ cells. (DO)
Synonyms:exact_synonym: central nervous system germ cell tumour;   germ cell tumor of the CNS;   germ cell tumour of the CNS
 primary_id: RDO:9003450
 xref: NCI:C5461
For additional species annotation, visit the Alliance of Genome Resources.

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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14620
    disease of cellular proliferation 7049
      Neoplasms by Histologic Type 4865
        Gonadal Tissue Neoplasms 134
          germ cell cancer 110
            central nervous system germ cell tumor 0
              central nervous system adult germ cell tumor + 0
              central nervous system childhood germ cell tumor + 0
              central nervous system embryonal carcinoma 0
              central nervous system endodermal sinus tumor 0
              central nervous system germinoma + 0
              central nervous system neuroblastoma + 0
              central nervous system teratoma + 0
Path 2
Term Annotations click to browse term
  disease 14620
    disease of cellular proliferation 7049
      Neoplasms by Site 6546
        organ system cancer 4988
          nervous system cancer 899
            central nervous system cancer 738
              central nervous system germ cell tumor 0
                central nervous system adult germ cell tumor + 0
                central nervous system childhood germ cell tumor + 0
                central nervous system embryonal carcinoma 0
                central nervous system endodermal sinus tumor 0
                central nervous system germinoma + 0
                central nervous system neuroblastoma + 0
                central nervous system teratoma + 0
paths to the root