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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:143116 term browser browse the term
Definition:A member of the class of oxindoles that is 5-acetyl-3-methylidene-1,3-dihydro-2H-indol-2-one in which one of the hydrogens of the methylidene group is substituted by a 2,2-dimethylhydrazinyl group and the other hydrogen is substituted by an ethyl group. It is a DYRK1B kinase inhibitor.
Synonyms:exact_synonym: (3E)-5-acetyl-3-[1-(2,2-dimethylhydrazinyl)propylidene]-1,3-dihydro-2H-indol-2-one
 related_synonym: (E)-5-acetyl-3-(1-(2,2-dimethylhydrazineyl)propylidene)indolin-2-one;   Formula=C15H19N3O2;   InChI=1S/C15H19N3O2/c1-5-12(17-18(3)4)14-11-8-10(9(2)19)6-7-13(11)16-15(14)20/h6-8,17H,5H2,1-4H3,(H,16,20)/b14-12+;   InChIKey=DVQQRISDKCELNQ-WYMLVPIESA-N;   SMILES=O=C(C)C=1C=CC2=C(C1)/C(=C(/CC)\\NN(C)C)/C(N2)=O
 xref: Patent:WO2005087727

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Term Annotations click to browse term
  CHEBI ontology 19740
    chemical entity 19738
      atom 19738
        nonmetal atom 19678
          nitrogen atom 18877
            nitrogen molecular entity 18877
              hydrazines 10286
                BI00036838 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18798
                                    carbonyl compound 18798
                                      carboxylic acid 18518
                                        carboacyl group 17656
                                          univalent carboacyl group 17656
                                            carbamoyl group 17497
                                              carboxamide 17497
                                                lactam 8349
                                                  gamma-lactam 6615
                                                    oxindoles 5866
                                                      BI00036838 0
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