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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:manganese(II) chloride
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Accession:CHEBI:63041 term browser browse the term
Definition:An inorganic chloride in which manganese(II) is coordinated to two chloride ions. In its anhydrous state manganese(II) chloride is a polymeric solid, which adopts a layered cadmium chloride-like structure.
Synonyms:exact_synonym: manganese(2+) dichloride
 related_synonym: Formula=Cl2Mn;   InChI=1S/2ClH.Mn/h2*1H;/q;;+2/p-2;   InChIKey=GLFNIEUTAYBVOC-UHFFFAOYSA-L;   Mangandichlorid;   Manganese bichloride;   Manganese(II) chloride (1:2);   Manganous chloride;   SMILES=Cl[Mn]Cl;   dichlorure de manganese;   manganese(II) dichloride;   manganous dichloride
 xref: CAS:7773-01-5
 xref_mesh: MESH:C025340
 xref: MetaCyc:CPD0-2394;   PMID:101555;   PMID:146543;   PMID:19801673;   PMID:3143594;   PMID:4476198;   PMID:4771199;   PMID:98204;   Reaxys:8128170;   Wikipedia:Manganese(II)_chloride



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manganese(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A630001G21Rikl RIKEN cDNA A630001G21 gene like increases expression EXP manganese chloride results in increased expression of A630001G21RIKL mRNA CTD PMID:28801915 NCBI chr 9:86,381,777...86,405,385
Ensembl chr 9:86,383,201...86,405,361
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 decreases expression ISO manganese chloride results in decreased expression of ABCA5 mRNA CTD PMID:17175027 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976
JBrowse link
G Abca9 ATP binding cassette subfamily A member 9 increases expression ISO manganese chloride results in increased expression of ABCA9 mRNA CTD PMID:17175027 NCBI chr10:95,077,615...95,137,751
Ensembl chr10:95,079,058...95,139,608
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP manganese chloride results in increased expression of ABCB1A mRNA CTD PMID:26745496 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP manganese chloride results in increased expression of ABCB1B mRNA CTD PMID:28801915 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
decreases methylation
EXP manganese chloride results in increased expression of ABCC2 mRNA
manganese chloride results in decreased methylation of ABCC2 gene
CTD PMID:28801915 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of ABCC8 protein CTD PMID:32659473 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Abi2 abl-interactor 2 increases expression ISO manganese chloride results in increased expression of ABI2 mRNA CTD PMID:17175027 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Abitram actin binding transcription modulator increases expression EXP manganese chloride results in increased expression of ABITRAM mRNA CTD PMID:28801915 NCBI chr 5:71,505,848...71,524,224
Ensembl chr 5:71,505,813...71,511,890
JBrowse link
G Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 increases expression EXP manganese chloride results in increased expression of ACAP1 mRNA CTD PMID:28801915 NCBI chr10:54,605,323...54,619,472
Ensembl chr10:54,605,323...54,619,472
JBrowse link
G Ace angiotensin I converting enzyme increases expression EXP manganese chloride results in increased expression of ACE mRNA CTD PMID:28801915 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ache acetylcholinesterase increases activity
increases expression
multiple interactions
decreases activity
EXP
ISO
manganese chloride results in increased activity of ACHE protein
manganese chloride results in increased expression of ACHE mRNA
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of ACHE protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein]; Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased expression of ACHE mRNA]
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACHE mRNA alternative form
CTD PMID:20503066 PMID:22033861 PMID:22154916 PMID:22192907 PMID:30738988 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Aco1 aconitase 1 increases activity EXP manganese chloride results in increased activity of ACO1 protein CTD PMID:15893546 PMID:16545456 PMID:16568477 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 multiple interactions
decreases expression
decreases activity
ISO
EXP
ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
manganese chloride results in decreased expression of ACO2 mRNA; manganese chloride results in decreased expression of ACO2 protein
Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
CTD PMID:9675333 PMID:16625280 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP manganese chloride results in increased expression of ACOT2 mRNA CTD PMID:28801915 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
increases methylation
EXP manganese chloride results in increased expression of ACP5 mRNA
manganese chloride results in increased methylation of ACP5 gene
CTD PMID:22281203 PMID:28801915 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Acr acrosin increases expression EXP manganese chloride results in increased expression of ACR mRNA CTD PMID:28801915 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO manganese chloride results in decreased expression of ACSL3 mRNA CTD PMID:15295902 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP manganese chloride results in decreased expression of ACSS2 mRNA CTD PMID:28801915 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression EXP manganese chloride results in decreased expression of ACTA1 mRNA CTD PMID:26745496 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP manganese chloride results in increased expression of ACTA2 mRNA CTD PMID:28801915 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta decreases expression
increases expression
ISO manganese chloride results in decreased expression of ACTB protein
manganese chloride results in increased expression of ACTB mRNA
CTD PMID:20452446 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression EXP manganese chloride results in increased expression of ACVRL1 mRNA CTD PMID:28801915 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression EXP manganese chloride results in increased expression of ADAM19 mRNA CTD PMID:28801915 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression EXP manganese chloride results in decreased expression of ADAMTS1 mRNA CTD PMID:28801915 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression EXP manganese chloride results in decreased expression of ADAMTS5 mRNA CTD PMID:28801915 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression EXP manganese chloride results in increased expression of ADCY6 mRNA CTD PMID:28801915 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
JBrowse link
G Add2 adducin 2 increases expression EXP manganese chloride results in increased expression of ADD2 mRNA CTD PMID:28801915 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression EXP manganese chloride results in increased expression of ADIPOQ mRNA CTD PMID:28801915 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adm adrenomedullin increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of ADM mRNA
manganese chloride results in decreased expression of ADM mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP manganese chloride results in increased expression of ADORA2A mRNA CTD PMID:28801915 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP manganese chloride results in increased expression of AEN mRNA CTD PMID:28801915 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aff1 ALF transcription elongation factor 1 increases expression EXP manganese chloride results in increased expression of AFF1 mRNA CTD PMID:28801915 NCBI chr14:5,861,188...6,024,196
Ensembl chr14:5,863,961...6,024,729
JBrowse link
G Afmid arylformamidase increases expression EXP manganese chloride results in increased expression of AFMID mRNA CTD PMID:28801915 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Afp alpha-fetoprotein decreases expression EXP manganese chloride results in decreased expression of AFP mRNA CTD PMID:26745496 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression EXP manganese chloride results in increased expression of AHNAK2 mRNA CTD PMID:28801915 NCBI chr 6:131,830,668...131,876,311 JBrowse link
G Aicda activation-induced cytidine deaminase increases expression EXP manganese chloride results in increased expression of AICDA mRNA CTD PMID:28801915 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO manganese chloride results in increased expression of AIF1 protein CTD PMID:28595911 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akap7 A-kinase anchoring protein 7 decreases expression ISO manganese chloride results in decreased expression of AKAP7 mRNA CTD PMID:17175027 NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression EXP manganese chloride results in increased expression of AKR1B1 mRNA CTD PMID:22281203 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in decreased phosphorylation of AKT1 protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
CTD PMID:30040983 PMID:31676349 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions EXP [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate co-treated with Mercuric Chloride co-treated with chromium trioxide co-treated with nickel chloride co-treated with manganese chloride co-treated with ferric chloride] results in decreased expression of ALB protein CTD PMID:17657459 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH18A1 mRNA CTD PMID:28801915 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP manganese chloride results in decreased expression of ALDH1A1 mRNA CTD PMID:28801915 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH4A1 mRNA CTD PMID:28801915 NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP manganese chloride results in increased expression of ALDOA mRNA CTD PMID:22281203 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression EXP manganese chloride results in decreased expression of ALDOC mRNA CTD PMID:28801915 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression EXP manganese chloride results in increased expression of ALKAL1 mRNA CTD PMID:28801915 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 increases expression EXP manganese chloride results in increased expression of AMIGO3 mRNA CTD PMID:28801915 NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555
JBrowse link
G Angpt2 angiopoietin 2 decreases expression EXP manganese chloride results in decreased expression of ANGPT2 mRNA CTD PMID:26745496 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO manganese chloride results in increased expression of ANGPTL4 mRNA CTD PMID:17175027 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankrd28 ankyrin repeat domain 28 increases expression EXP manganese chloride results in increased expression of ANKRD28 mRNA CTD PMID:28801915 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249
JBrowse link
G Ano3 anoctamin 3 increases expression EXP manganese chloride results in increased expression of ANO3 mRNA CTD PMID:28801915 NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ANP32A mRNA CTD PMID:35690225 NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443
JBrowse link
G Anxa3 annexin A3 decreases expression EXP manganese chloride results in decreased expression of ANXA3 mRNA CTD PMID:28801915 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Aopep aminopeptidase O decreases expression EXP manganese chloride results in decreased expression of AOPEP mRNA CTD PMID:28801915 NCBI chr17:1,811,281...2,127,316
Ensembl chr17:1,811,980...2,127,331
JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 increases expression ISO manganese chloride results in increased expression of AP3B2 mRNA CTD PMID:17175027 NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression EXP manganese chloride results in increased expression of APBB3 mRNA CTD PMID:28801915 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression
increases methylation
ISO manganese chloride results in decreased expression of APC mRNA
manganese chloride results in increased methylation of APC gene
CTD PMID:27913844 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP manganese chloride results in decreased expression of APOA2 mRNA CTD PMID:28801915 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apol2 apolipoprotein L2 increases expression ISO manganese chloride results in increased expression of APOL2 mRNA CTD PMID:17175027 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558
JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression EXP manganese chloride results in increased expression of APOLD1 mRNA CTD PMID:28801915 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP manganese chloride results in decreased expression of AQP3 mRNA CTD PMID:28801915 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Areg amphiregulin increases expression EXP manganese chloride results in increased expression of AREG mRNA CTD PMID:28801915 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg1 arginase 1 increases expression
increases methylation
multiple interactions
EXP
ISO
manganese chloride results in increased expression of ARG1 mRNA
manganese chloride results in increased methylation of ARG1 gene
[manganese chloride results in increased abundance of Manganese] which results in increased expression of ARG1 mRNA
CTD PMID:28801915 PMID:34018660 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP manganese chloride results in decreased expression of ARHGAP24 mRNA CTD PMID:28801915 NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO manganese chloride results in decreased expression of ARHGDIA mRNA CTD PMID:17175027 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 increases expression EXP manganese chloride results in increased expression of ARHGEF10 mRNA CTD PMID:28801915 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 increases expression EXP manganese chloride results in increased expression of ARHGEF16 mRNA CTD PMID:28801915 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212
JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 increases expression
increases methylation
ISO
EXP
manganese chloride results in increased expression of ARHGEF4 mRNA
manganese chloride results in increased methylation of ARHGEF4 gene
CTD PMID:17175027 PMID:28801915 NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075
JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression EXP manganese chloride results in increased expression of ARHGEF6 mRNA CTD PMID:28801915 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 decreases expression EXP manganese chloride results in decreased expression of ARHGEF7 mRNA CTD PMID:28801915 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697
JBrowse link
G Arid3a AT-rich interaction domain 3A increases expression EXP manganese chloride results in increased expression of ARID3A mRNA CTD PMID:28801915 NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599
JBrowse link
G Arl4c ARF like GTPase 4C increases methylation
increases expression
EXP manganese chloride results in increased methylation of ARL4C gene
manganese chloride results in increased expression of ARL4C mRNA
CTD PMID:28801915 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT gene mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein] CTD PMID:19263519 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 decreases expression EXP manganese chloride results in decreased expression of ASB5 mRNA CTD PMID:28801915 NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP manganese chloride results in increased expression of ASNS mRNA CTD PMID:28801915 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP manganese chloride results in increased expression of ASS1 mRNA CTD PMID:28801915 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Aste1 asteroid homolog 1 increases expression EXP manganese chloride results in increased expression of ASTE1 mRNA CTD PMID:28801915 NCBI chr 8:106,026,570...106,044,694
Ensembl chr 8:106,026,515...106,044,430
JBrowse link
G Atf1 activating transcription factor 1 increases phosphorylation
multiple interactions
EXP manganese chloride results in increased phosphorylation of ATF1 protein
SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of ATF1 protein]
CTD PMID:16787641 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atf2 activating transcription factor 2 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of ATF2 protein
manganese chloride results in increased phosphorylation of ATF2 protein
CTD PMID:19084589 PMID:20152896 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
EXP manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of ATF4 mRNA]
manganese chloride results in increased expression of ATF4 mRNA; manganese chloride results in increased expression of ATF4 protein
CTD PMID:23934647 PMID:23948121 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 decreases expression
increases expression
ISO
EXP
manganese chloride results in decreased expression of ATF6 mRNA
manganese chloride results in increased expression of ATF6 protein
CTD PMID:17175027 PMID:25732873 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of ATM mRNA CTD PMID:17175027 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression EXP manganese chloride results in decreased expression of ATOH8 mRNA CTD PMID:26745496 PMID:28801915 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of ATP1A2 protein CTD PMID:37598760 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which affects the expression of ATP1A3 protein CTD PMID:37598760 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases methylation EXP manganese chloride results in increased methylation of ATP2A3 gene CTD PMID:28801915 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of ATP2B2 gene
manganese chloride results in decreased expression of ATP2B2 mRNA
CTD PMID:27913844 NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression EXP manganese chloride results in increased expression of ATP2B4 mRNA CTD PMID:28801915 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression EXP manganese chloride results in decreased expression of ATP5F1C mRNA CTD PMID:22281203 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression EXP manganese chloride results in increased expression of ATP6V1A mRNA CTD PMID:28801915 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1e2 ATPase H+ transporting V1 subunit E2 decreases expression EXP
ISO
manganese chloride results in decreased expression of ATP6V1E2 mRNA CTD PMID:28801915 NCBI chr 6:7,667,359...7,673,711
Ensembl chr 6:7,667,564...7,672,626
JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ATP6V1H mRNA; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of ATP6V1H mRNA] CTD PMID:31690173 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962
JBrowse link
G Atp7a ATPase copper transporting alpha decreases expression
affects localization
EXP manganese chloride results in decreased expression of ATP7A mRNA; manganese chloride results in decreased expression of ATP7A protein
manganese chloride affects the localization of ATP7A protein
CTD PMID:24614235 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Atp7b ATPase copper transporting beta affects localization
decreases expression
EXP manganese chloride affects the localization of ATP7B protein
manganese chloride results in decreased expression of ATP7B mRNA; manganese chloride results in decreased expression of ATP7B protein
CTD PMID:24614235 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 decreases expression ISO manganese chloride results in decreased expression of ATP8A1 mRNA CTD PMID:17175027 NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611
JBrowse link
G Avil advillin decreases expression
increases methylation
EXP manganese chloride results in decreased expression of AVIL mRNA
manganese chloride results in increased methylation of AVIL gene
CTD PMID:28801915 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071
JBrowse link
G Axin2 axin 2 increases expression EXP manganese chloride results in increased expression of AXIN2 mRNA CTD PMID:28801915 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP manganese chloride results in increased expression of BACH1 mRNA CTD PMID:28801915 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of BAX mRNA; manganese chloride results in increased expression of BAX protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BAX protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; Estradiol inhibits the reaction [manganese chloride results in increased expression of BAX protein]; Tamoxifen inhibits the reaction [manganese chloride results in increased expression of BAX protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of BAX protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; manganese chloride results in increased expression of and affects the localization of BAX protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:29183790 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases nitrosation
increases expression
EXP
ISO
manganese chloride results in decreased expression of BCL2 mRNA; manganese chloride results in decreased expression of BCL2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BCL2 protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of BCL2 protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein]; manganese chloride results in decreased expression of and affects the localization of BCL2 protein
manganese chloride results in increased nitrosation of BCL2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 mRNA; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased nitrosation of BCL2 protein]
manganese chloride results in increased expression of BCL2 mRNA
manganese chloride results in increased expression of BCL2 protein
CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:28801915 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP manganese chloride results in decreased expression of BCL2L1 protein CTD PMID:27107493 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
decreases expression
EXP manganese chloride results in increased expression of BCL2L11 protein
manganese chloride results in decreased expression of BCL2L11 mRNA
CTD PMID:25732873 PMID:28801915 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl6b BCL6B, transcription repressor increases expression EXP manganese chloride results in increased expression of BCL6B mRNA CTD PMID:28801915 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression EXP manganese chloride results in increased expression of BDKRB2 mRNA CTD PMID:28801915 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
increases expression
increases methylation
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of BDNF mRNA
manganese chloride results in increased expression of BDNF mRNA
manganese chloride results in increased methylation of BDNF gene
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]
CTD PMID:25698507 PMID:28801915 PMID:30951808 PMID:32659473 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
decreases expression
affects expression
EXP
ISO
manganese chloride results in increased expression of BECN1 protein
wortmannin inhibits the reaction [manganese chloride results in increased expression of BECN1 protein]
manganese chloride results in decreased expression of BECN1 protein
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]
manganese chloride affects the expression of BECN1 protein
CTD PMID:23604964 PMID:28856835 PMID:30578841 PMID:30672645 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression EXP manganese chloride results in increased expression of BHLHE40 mRNA CTD PMID:28801915 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
increases expression
multiple interactions
EXP manganese chloride results in increased cleavage of BID protein
manganese chloride results in increased expression of BID protein; manganese chloride results in increased expression of BID protein modified form
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein]
CTD PMID:21704098 PMID:28378122 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
EXP Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA] CTD PMID:24464479 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 increases expression EXP manganese chloride results in increased expression of BIRC7 mRNA CTD PMID:28801915 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606
JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 increases expression EXP manganese chloride results in increased expression of BLOC1S3 mRNA CTD PMID:28801915 NCBI chr 1:79,155,873...79,158,247
Ensembl chr 1:79,155,693...79,158,505
JBrowse link
G Blvra biliverdin reductase A increases expression EXP manganese chloride results in increased expression of BLVRA mRNA CTD PMID:22281203 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression EXP manganese chloride results in decreased expression of BMAL1 mRNA CTD PMID:28511934 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Bmf Bcl2 modifying factor decreases expression EXP manganese chloride results in decreased expression of BMF mRNA CTD PMID:28801915 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO manganese chloride results in increased expression of BMP4 mRNA CTD PMID:17467022 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
affects response to substance
ISO [N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cycloheximide inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Dactinomycin inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Glutathione inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; manganese chloride results in increased expression of and affects the localization of BNIP3 protein
BNIP3 protein affects the susceptibility to manganese chloride
CTD PMID:19442826 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bpifb6 BPI fold containing family B, member 6 increases expression EXP manganese chloride results in increased expression of BPIFB6 mRNA CTD PMID:28801915 NCBI chr 3:142,381,478...142,395,304
Ensembl chr 3:142,381,374...142,395,308
JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) increases expression EXP manganese chloride results in increased expression of BSN mRNA CTD PMID:28801915 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819
JBrowse link
G Btnl5 butyrophilin-like 5 decreases expression EXP manganese chloride results in decreased expression of BTNL5 mRNA CTD PMID:28801915 NCBI chr20:4,366,780...4,376,385
Ensembl chr20:4,365,793...4,376,385
JBrowse link
G Btnl7 butyrophilin-like 7 decreases expression EXP manganese chloride results in decreased expression of BTNL7 mRNA CTD PMID:28801915 NCBI chr20:4,301,078...4,313,522
Ensembl chr20:4,301,854...4,313,274
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of BUB1 mRNA CTD PMID:17175027 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G C10h16orf90 similar to human chromosome 16 open reading frame 90 increases expression EXP manganese chloride results in increased expression of C10H16ORF90 mRNA CTD PMID:28801915 NCBI chr10:11,618,867...11,632,151
Ensembl chr10:11,618,348...11,629,910
JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression EXP manganese chloride results in increased expression of C1QTNF4 mRNA CTD PMID:28801915 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression EXP manganese chloride results in increased expression of C2CD4B mRNA CTD PMID:28801915 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP manganese chloride results in decreased expression of C4BPA mRNA CTD PMID:28801915 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C5 complement C5 decreases expression EXP manganese chloride results in decreased expression of C5 mRNA CTD PMID:28801915 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G C5l1 complement C5 like 1 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of C5L1 gene
manganese chloride results in decreased expression of C5L1 mRNA
CTD PMID:28801915 NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054
JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression EXP manganese chloride results in decreased expression of CABLES1 mRNA CTD PMID:28801915 NCBI chr18:3,076,556...3,181,181
Ensembl chr18:3,075,524...3,181,181
JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 increases expression ISO manganese chloride results in increased expression of CALCOCO2 mRNA CTD PMID:17175027 NCBI chr10:81,055,467...81,069,298 JBrowse link
G Cald1 caldesmon 1 increases expression EXP manganese chloride results in increased expression of CALD1 mRNA CTD PMID:28801915 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP manganese chloride results in increased expression of CALY mRNA CTD PMID:28801915 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO manganese chloride results in increased expression of CAMKK2 mRNA CTD PMID:15295902 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Camkv CaM kinase-like vesicle-associated decreases expression EXP manganese chloride results in decreased expression of CAMKV mRNA CTD PMID:28801915 NCBI chr 8:108,626,821...108,641,169
Ensembl chr 8:108,626,821...108,641,169
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression EXP manganese chloride results in increased expression of CAMP mRNA CTD PMID:28801915 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression EXP manganese chloride results in increased expression of CAMTA2 mRNA CTD PMID:28801915 NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558
JBrowse link
G Capn5 calpain 5 increases expression EXP manganese chloride results in increased expression of CAPN5 mRNA CTD PMID:28801915 NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923
JBrowse link
G Car5b carbonic anhydrase 5B decreases expression EXP manganese chloride results in decreased expression of CAR5B mRNA CTD PMID:28801915 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837
JBrowse link
G Car8 carbonic anhydrase 8 increases expression EXP manganese chloride results in increased expression of CAR8 mRNA CTD PMID:26745496 NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374
JBrowse link
G Card14 caspase recruitment domain family, member 14 increases methylation ISO manganese chloride results in increased methylation of CARD14 gene CTD PMID:27913844 NCBI chr10:104,572,059...104,601,606
Ensembl chr10:104,566,424...104,601,905
JBrowse link
G Card9 caspase recruitment domain family, member 9 decreases expression EXP manganese chloride results in decreased expression of CARD9 mRNA CTD PMID:28801915 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Casp12 caspase 12 multiple interactions
increases expression
increases cleavage
ISO
EXP
Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein]; manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein
manganese chloride results in increased expression of CASP12 mRNA; manganese chloride results in increased expression of CASP12 protein
SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein]
manganese chloride results in increased cleavage of CASP12 protein
Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP12 protein]
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:26064043 More... NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp2 caspase 2 increases expression EXP manganese chloride results in increased expression of CASP2 mRNA CTD PMID:28801915 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
increases activity
increases methylation
ISO
EXP
manganese chloride results in increased cleavage of CASP3 protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of CASP3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein]; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 mRNA]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]
manganese chloride results in increased expression of CASP3 mRNA; manganese chloride results in increased expression of CASP3 protein; manganese chloride results in increased expression of CASP3 protein modified form
[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
manganese chloride results in increased methylation of CASP3 gene
CTD PMID:16787641 PMID:17483122 PMID:18178165 PMID:19815061 PMID:23764342 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases expression EXP manganese chloride results in increased expression of CASP4 mRNA CTD PMID:28801915 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions
EXP manganese chloride results in increased cleavage of CASP8 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]
CTD PMID:21704098 PMID:28378122 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases cleavage
ISO
EXP
manganese chloride results in increased activity of CASP9 protein
PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
manganese chloride results in increased cleavage of CASP9 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]
CTD PMID:16787641 PMID:17483122 PMID:21704098 PMID:25416158 PMID:28378122 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity
multiple interactions
decreases expression
EXP
ISO
manganese chloride results in decreased activity of CAT protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; [Plant Extracts co-treated with manganese chloride] results in increased expression of CAT protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of CAT protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of CAT protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased activity of CAT protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CAT protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein]; Quercetin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]
CTD PMID:20503066 PMID:22033861 PMID:22192907 PMID:26064043 PMID:28040552 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Catip ciliogenesis associated TTC17 interacting protein increases expression EXP manganese chloride results in increased expression of CATIP mRNA CTD PMID:28801915 NCBI chr 9:75,945,960...75,953,618
Ensembl chr 9:75,945,961...75,953,607
JBrowse link
G Catsperd cation channel sperm associated auxiliary subunit delta increases expression EXP manganese chloride results in increased expression of CATSPERD mRNA CTD PMID:28801915 NCBI chr 9:1,459,967...1,498,342
Ensembl chr 9:1,460,001...1,498,344
JBrowse link
G Cav2 caveolin 2 decreases expression EXP manganese chloride results in decreased expression of CAV2 mRNA CTD PMID:28801915 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression EXP manganese chloride results in increased expression of DOS mRNA CTD PMID:28801915 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Cbs cystathionine beta synthase decreases expression EXP manganese chloride results in decreased expression of CBS mRNA CTD PMID:28801915 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression EXP manganese chloride results in increased expression of CCDC15 mRNA CTD PMID:28801915 NCBI chr 8:36,991,147...37,068,849
Ensembl chr 8:36,998,867...37,068,919
JBrowse link
G Ccdc175 coiled-coil domain containing 175 increases expression EXP manganese chloride results in increased expression of CCDC175 mRNA CTD PMID:28801915 NCBI chr 6:90,661,948...90,745,015
Ensembl chr 6:90,662,269...90,744,963
JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression EXP manganese chloride results in increased expression of CCDC96 mRNA CTD PMID:28801915 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression EXP manganese chloride results in increased expression of CCL17 mRNA CTD PMID:28801915 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression EXP manganese chloride results in increased expression of CCL19 mRNA CTD PMID:28801915 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
ISO
EXP
manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
manganese chloride results in decreased secretion of CCL2 protein
CTD PMID:23329836 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP manganese chloride results in increased expression of CCL5 mRNA CTD PMID:28801915 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO
EXP
manganese chloride results in increased expression of CCL7 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
increases methylation
ISO
EXP
manganese chloride results in increased expression of CCN2 mRNA
manganese chloride results in increased methylation of CCN2 gene
CTD PMID:17467022 PMID:28801915 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna1 cyclin A1 increases expression EXP manganese chloride results in increased expression of CCNA1 mRNA CTD PMID:26745496 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 protein CTD PMID:34822792 PMID:38503349 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of CCNB2 mRNA
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA]; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein]
CTD PMID:17175027 PMID:34822792 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of CCND1 mRNA CTD PMID:38503349 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNE1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNE1 protein CTD PMID:38503349 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccng1 cyclin G1 increases expression EXP manganese chloride results in increased expression of CCNG1 mRNA CTD PMID:28801915 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd44 CD44 molecule increases expression EXP manganese chloride results in increased expression of CD44 mRNA CTD PMID:28801915 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd48 Cd48 molecule increases expression ISO manganese chloride results in increased expression of CD48 mRNA CTD PMID:17175027 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
JBrowse link
G Cd6 Cd6 molecule decreases expression EXP manganese chloride results in decreased expression of CD6 mRNA CTD PMID:28801915 NCBI chr 1:207,442,873...207,481,703
Ensembl chr 1:207,442,877...207,481,634
JBrowse link
G Cd74 CD74 molecule increases expression EXP manganese chloride results in increased expression of CD74 mRNA CTD PMID:28801915 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd86 CD86 molecule increases expression ISO manganese chloride results in increased expression of CD86 protein CTD PMID:15737199 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cd8b CD8 subunit beta increases expression ISO manganese chloride results in increased expression of CD8B mRNA; manganese chloride results in increased expression of CD8B1 mRNA CTD PMID:17175027 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression EXP manganese chloride results in increased expression of CDC42EP3 mRNA CTD PMID:28801915 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression EXP manganese chloride results in decreased expression of CDHR4 mRNA CTD PMID:28801915 NCBI chr 8:108,682,594...108,690,358
Ensembl chr 8:108,682,613...108,690,367
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
affects localization
EXP Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein]
manganese chloride results in increased expression of CDKN1A mRNA; manganese chloride results in increased expression of CDKN1A protein
manganese chloride affects the localization of CDKN1A protein
CTD PMID:22542671 PMID:28801915 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression EXP manganese chloride results in decreased expression of CDKN1C mRNA CTD PMID:28801915 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP manganese chloride results in increased expression of CDKN2B mRNA CTD PMID:28801915 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO manganese chloride results in decreased expression of CDKN2C mRNA CTD PMID:17175027 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO manganese chloride results in decreased expression of CDKN3 mRNA CTD PMID:17175027 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression EXP manganese chloride results in increased expression of CDNF mRNA CTD PMID:28801915 NCBI chr17:74,714,564...74,728,639
Ensembl chr17:74,713,564...74,728,639
JBrowse link
G Cdyl2 chromodomain Y-like 2 increases expression EXP manganese chloride results in increased expression of CDYL2 mRNA CTD PMID:28801915 NCBI chr19:44,591,734...44,783,258
Ensembl chr19:44,597,459...44,783,022
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO manganese chloride results in increased expression of CEBPD mRNA CTD PMID:17175027 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 increases expression ISO manganese chloride results in increased expression of CELSR1 mRNA CTD PMID:17175027 NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164
JBrowse link
G Cep112 centrosomal protein 112 increases expression EXP manganese chloride results in increased expression of CEP112 mRNA CTD PMID:28801915 NCBI chr10:93,366,059...93,833,133
Ensembl chr10:93,366,136...93,833,131
JBrowse link
G Cep128 centrosomal protein 128 decreases expression ISO manganese chloride results in decreased expression of CEP128 mRNA CTD PMID:17175027 NCBI chr 6:109,951,009...110,328,686
Ensembl chr 6:109,951,061...110,328,713
JBrowse link
G Cers1 ceramide synthase 1 increases expression EXP manganese chloride results in increased expression of CERS1 mRNA CTD PMID:28801915 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Cers6 ceramide synthase 6 increases expression EXP manganese chloride results in increased expression of CERS6 mRNA CTD PMID:28801915 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression EXP manganese chloride results in increased expression of CFLAR mRNA CTD PMID:28801915 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cftr CF transmembrane conductance regulator increases expression EXP manganese chloride results in increased expression of CFTR mRNA CTD PMID:28801915 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression EXP manganese chloride results in increased expression of CGREF1 mRNA CTD PMID:28801915 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852
JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP manganese chloride results in increased expression of CH25H mRNA CTD PMID:28801915 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CHAT protein CTD PMID:30738988 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chml CHM like Rab escort protein increases expression EXP manganese chloride results in increased expression of CHML mRNA CTD PMID:28801915 NCBI chr13:87,609,647...87,619,868
Ensembl chr13:87,589,298...87,619,862
JBrowse link
G Chmp4b charged multivesicular body protein 4B multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of CHMP4B protein CTD PMID:35690225 NCBI chr 3:143,170,859...143,211,376
Ensembl chr 3:143,170,902...143,210,844
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases expression ISO manganese chloride results in decreased expression of CHRNA7 protein CTD PMID:25874029 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 increases expression EXP manganese chloride results in increased expression of CHST10 mRNA CTD PMID:28801915 NCBI chr 9:41,092,805...41,122,737
Ensembl chr 9:41,092,808...41,122,503
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression EXP manganese chloride results in increased expression of CHST5 mRNA CTD PMID:28801915 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases phosphorylation
EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased phosphorylation of CHUK protein] CTD PMID:22245093 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression EXP manganese chloride results in increased expression of CIITA mRNA CTD PMID:28801915 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression EXP manganese chloride results in increased expression of CISH mRNA CTD PMID:28801915 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 decreases expression EXP manganese chloride results in decreased expression of CITED1 mRNA CTD PMID:28801915 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162
JBrowse link
G Cited1l1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 like 1 decreases expression EXP manganese chloride results in decreased expression of CITED1L1 mRNA CTD PMID:28801915 NCBI chr 1:204,760,742...204,761,351 JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO manganese chloride results in decreased expression of CKS2 mRNA CTD PMID:17175027 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn23 claudin 23 increases expression EXP manganese chloride results in increased expression of CLDN23 mRNA CTD PMID:26745496 NCBI chr16:56,413,677...56,415,401
Ensembl chr16:56,413,381...56,415,523
JBrowse link
G Cldn4 claudin 4 increases expression EXP manganese chloride results in increased expression of CLDN4 mRNA CTD PMID:28801915 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Cldn9 claudin 9 decreases expression EXP manganese chloride results in decreased expression of CLDN9 mRNA CTD PMID:28801915 NCBI chr10:12,714,137...12,715,568 JBrowse link
G Cldnd1 claudin domain containing 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CLDND1 mRNA CTD PMID:35690225 NCBI chr11:41,883,120...41,889,471
Ensembl chr11:41,883,134...41,889,354
JBrowse link
G Clec4f C-type lectin domain family 4, member F increases methylation EXP manganese chloride results in increased methylation of CLEC4F gene CTD PMID:28801915 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Clock clock circadian regulator decreases expression EXP manganese chloride results in decreased expression of CLOCK mRNA CTD PMID:28511934 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression
increases methylation
EXP manganese chloride results in increased expression of CMPK2 mRNA
manganese chloride results in increased methylation of CMPK2 gene
CTD PMID:28801915 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
JBrowse link
G Cnksr1 connector enhancer of kinase suppressor of Ras 1 increases expression EXP manganese chloride results in increased expression of CNKSR1 mRNA CTD PMID:28801915 NCBI chr 5:146,447,495...146,458,332
Ensembl chr 5:146,447,497...146,458,212
JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 decreases expression ISO manganese chloride results in decreased expression of CNOT2 mRNA CTD PMID:17175027 NCBI chr 7:52,130,445...52,222,338
Ensembl chr 7:52,130,441...52,223,575
JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like increases expression ISO manganese chloride results in increased expression of CNOT6L mRNA CTD PMID:17175027 NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203
JBrowse link
G Cntn4 contactin 4 decreases expression ISO manganese chloride results in decreased expression of CNTN4 mRNA CTD PMID:15295902 NCBI chr 4:138,624,584...139,622,499
Ensembl chr 4:139,099,152...139,621,090
JBrowse link
G Col12a1 collagen type XII alpha 1 chain decreases expression ISO manganese chloride results in decreased expression of COL12A1 mRNA CTD PMID:17175027 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
JBrowse link
G Col15a1 collagen type XV alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL15A1 mRNA CTD PMID:28801915 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Col17a1 collagen type XVII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL17A1 mRNA CTD PMID:28801915 NCBI chr 1:246,530,589...246,577,559
Ensembl chr 1:246,531,367...246,577,632
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO manganese chloride results in increased expression of COL18A1 mRNA CTD PMID:17467022 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593
JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression EXP manganese chloride results in decreased expression of COL4A5 mRNA CTD PMID:28801915 NCBI chr  X:105,118,762...105,322,699
Ensembl chr  X:105,118,820...105,322,692
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression EXP manganese chloride results in increased expression of COL5A2 mRNA CTD PMID:28801915 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL6A1 mRNA CTD PMID:28801915 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
JBrowse link
G Col7a1 collagen type VII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL7A1 mRNA CTD PMID:28801915 NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain increases expression EXP manganese chloride results in increased expression of COL8A1 mRNA CTD PMID:28801915 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
JBrowse link
G Colec10 collectin subfamily member 10 decreases expression EXP manganese chloride results in decreased expression of COLEC10 mRNA CTD PMID:28801915 NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675
JBrowse link
G Colec12 collectin sub-family member 12 decreases expression EXP manganese chloride results in decreased expression of COLEC12 mRNA CTD PMID:28801915 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618
JBrowse link
G Copg2 COPI coat complex subunit gamma 2 increases expression EXP manganese chloride results in increased expression of COPG2 mRNA CTD PMID:28801915 NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression EXP manganese chloride results in increased expression of COX6A2 mRNA CTD PMID:28801915 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Cplx2 complexin 2 increases expression EXP manganese chloride results in increased expression of CPLX2 mRNA CTD PMID:28801915 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Cpm carboxypeptidase M decreases expression ISO manganese chloride results in decreased expression of CPM mRNA CTD PMID:17175027 NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220
JBrowse link
G Cracdl CRACD like increases expression EXP manganese chloride results in increased expression of CRACDL mRNA CTD PMID:28801915 NCBI chr 9:39,834,321...39,950,763
Ensembl chr 9:39,834,833...39,951,086
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in increased phosphorylation of CREB1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of CREB1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CREB1 protein; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]
CTD PMID:16787641 PMID:30951808 PMID:31676349 PMID:32659473 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebl2 cAMP responsive element binding protein-like 2 increases expression EXP manganese chloride results in increased expression of CREBL2 mRNA CTD PMID:28801915 NCBI chr 4:167,673,359...167,699,299
Ensembl chr 4:167,673,315...167,699,292
JBrowse link
G Crk CRK proto-oncogene, adaptor protein increases expression EXP manganese chloride results in increased expression of CRK mRNA CTD PMID:28801915 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP manganese chloride results in decreased expression of CRY1 mRNA CTD PMID:28511934 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cryaa crystallin, alpha A increases methylation EXP manganese chloride results in increased methylation of CRYAA gene CTD PMID:28801915 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Cryab crystallin, alpha B decreases expression EXP manganese chloride results in decreased expression of CRYAB mRNA CTD PMID:28801915 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cryba4 crystallin, beta A4 increases expression EXP manganese chloride results in increased expression of CRYBA4 mRNA CTD PMID:28801915 NCBI chr12:44,378,734...44,393,226
Ensembl chr12:44,378,737...44,393,221
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases expression
ISO
EXP
manganese chloride promotes the reaction [SNCA protein results in increased expression of CSF2 mRNA]
manganese chloride results in increased expression of CSF2 mRNA
CTD PMID:28539244 PMID:28801915 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 increases expression EXP manganese chloride results in increased expression of CSF3 mRNA CTD PMID:28801915 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases expression
increases methylation
EXP manganese chloride results in increased expression of CSPG4 mRNA
manganese chloride results in increased methylation of CSPG4 gene
CTD PMID:28801915 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression EXP manganese chloride results in increased expression of CSRP3 mRNA CTD PMID:26745496 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 increases expression EXP manganese chloride results in increased expression of CSTF2 mRNA CTD PMID:28801915 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476
JBrowse link
G Ctnna1 catenin alpha 1 decreases expression ISO manganese chloride results in decreased expression of CTNNA1 mRNA CTD PMID:17175027 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
ISO
EXP
manganese chloride results in decreased expression of CTNNB1 mRNA
Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of CTNNB1 protein]
CTD PMID:17175027 PMID:24464479 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnd1 catenin delta 1 increases expression EXP manganese chloride results in increased expression of CTNND1 mRNA CTD PMID:28801915 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516
JBrowse link
G Cts7l2 cathepsin 7 like 2 increases expression EXP manganese chloride results in increased expression of CTS7L2 mRNA CTD PMID:28801915 NCBI chr17:3,903,602...3,907,088
Ensembl chr17:3,903,602...3,906,568
JBrowse link
G Ctsd cathepsin D increases expression
affects localization
multiple interactions
EXP
ISO
manganese chloride results in increased expression of CTSD protein
manganese chloride affects the localization of CTSD protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CTSD protein
CTD PMID:28378122 PMID:31690173 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsw cathepsin W increases expression EXP manganese chloride results in increased expression of CTSW mRNA CTD PMID:28801915 NCBI chr 1:202,772,395...202,777,021
Ensembl chr 1:202,772,572...202,775,964
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP manganese chloride results in increased expression of CX3CL1 mRNA CTD PMID:28801915 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases methylation
increases expression
EXP manganese chloride results in increased methylation of CXCL1 gene
manganese chloride results in increased expression of CXCL1 mRNA
CTD PMID:28801915 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO manganese chloride results in increased expression of CXCL10 mRNA CTD PMID:27427241 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP manganese chloride results in decreased expression of CXCL12 mRNA CTD PMID:28801915 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO manganese chloride results in increased expression of CXCL14 mRNA CTD PMID:17175027 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO
EXP
manganese chloride results in increased expression of CXCL2 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression EXP manganese chloride results in increased expression of CXCL3 mRNA CTD PMID:28801915 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO manganese chloride results in increased expression of CXCL6 mRNA CTD PMID:17175027 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxxc1 CXXC finger protein 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of CXXC1 gene
manganese chloride results in decreased expression of CXXC1 mRNA
CTD PMID:27913844 NCBI chr18:67,813,185...67,818,556
Ensembl chr18:67,813,206...67,818,551
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects localization
ISO BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cyclosporine inhibits the reaction [manganese chloride affects the localization of CYCS protein]
SNCA protein inhibits the reaction [manganese chloride affects the localization of CYCS protein]
CTD PMID:19442826 PMID:25416158 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
increases expression
EXP manganese chloride inhibits the reaction [CYP11A1 protein results in increased chemical synthesis of Progesterone]
manganese chloride results in decreased expression of CYP11A1 protein
manganese chloride results in increased expression of CYP11A1 mRNA
CTD PMID:12699903 PMID:25981801 PMID:28801915 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression EXP manganese chloride results in decreased expression of CYP26B1 mRNA CTD PMID:26745496 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of CYP4F4 gene
manganese chloride results in decreased expression of CYP4F4 mRNA
CTD PMID:28801915 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases methylation
increases expression
EXP manganese chloride results in increased methylation of CYRIA gene
manganese chloride results in increased expression of CYRIA mRNA
CTD PMID:28801915 NCBI chr 6:35,045,208...35,150,669
Ensembl chr 6:35,045,208...35,150,668
JBrowse link
G Dach2 dachshund family transcription factor 2 increases expression ISO manganese chloride results in increased expression of DACH2 mRNA CTD PMID:17175027 NCBI chr  X:78,718,963...79,018,023
Ensembl chr  X:78,451,593...79,017,592
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression EXP manganese chloride results in decreased expression of DACT1 mRNA CTD PMID:28801915 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
JBrowse link
G Dbh dopamine beta-hydroxylase increases methylation ISO manganese chloride results in increased methylation of DBH gene CTD PMID:27913844 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP manganese chloride results in increased expression of DBP mRNA CTD PMID:28511934 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcp1b decapping mRNA 1B increases expression EXP manganese chloride results in increased expression of DCP1B mRNA CTD PMID:28801915 NCBI chr 4:152,358,267...152,395,747
Ensembl chr 4:152,358,241...152,397,145
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO
EXP
Deferoxamine promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
[manganese chloride results in increased abundance of Manganese] which results in increased expression of DDIT3 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]
manganese chloride results in increased expression of DDIT3 mRNA; manganese chloride results in increased expression of DDIT3 protein
CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx60 DEXD/H-box helicase 60 increases expression EXP manganese chloride results in increased expression of DDX60 mRNA CTD PMID:28801915 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526
JBrowse link
G Defb29 defensin beta 29 increases methylation
increases expression
EXP manganese chloride results in increased methylation of DEFB29 gene
manganese chloride results in increased expression of DEFB29 mRNA
CTD PMID:28801915 NCBI chr 3:141,004,098...141,009,379
Ensembl chr 3:141,004,098...141,005,557
JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression EXP manganese chloride results in increased expression of DEPP1 mRNA CTD PMID:28801915 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 decreases expression EXP manganese chloride results in decreased expression of DHRS3 mRNA CTD PMID:28801915 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP manganese chloride results in decreased expression of DLD protein CTD PMID:25981801 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of DLK1 gene
manganese chloride results in decreased expression of DLK1 mRNA
CTD PMID:27913844 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dll4 delta like canonical Notch ligand 4 increases expression ISO manganese chloride results in increased expression of DLL4 mRNA CTD PMID:17467022 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Dmkn dermokine increases expression EXP manganese chloride results in increased expression of DMKN mRNA CTD PMID:28801915 NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006
JBrowse link
G Dnah14 dynein axonemal heavy chain 14 decreases expression ISO manganese chloride results in decreased expression of DNAH14 mRNA CTD PMID:17175027 NCBI chr13:93,322,653...93,540,706
Ensembl chr13:93,322,711...93,538,646
JBrowse link
G Dnai2 dynein, axonemal, intermediate chain 2 decreases expression EXP manganese chloride results in decreased expression of DNAI2 mRNA CTD PMID:28801915 NCBI chr10:99,759,966...99,793,379
Ensembl chr10:99,759,966...99,793,378
JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 increases expression EXP manganese chloride results in increased expression of DNAJC12 mRNA CTD PMID:28801915 NCBI chr20:25,246,744...25,267,508
Ensembl chr20:25,223,144...25,267,521
JBrowse link
G Dnajc16 DnaJ heat shock protein family (Hsp40) member C16 increases expression EXP manganese chloride results in increased expression of DNAJC16 mRNA CTD PMID:28801915 NCBI chr 5:154,073,372...154,106,246
Ensembl chr 5:154,075,261...154,106,136
JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions
ISO manganese chloride results in increased expression of DNM1L mRNA; manganese chloride results in increased expression of DNM1L protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]]; manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]; Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L mRNA]; Resveratrol inhibits the reaction [manganese chloride results in increased expression of DNM1L protein]
CTD PMID:34738708 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO manganese chloride results in decreased expression of DNPH1 mRNA CTD PMID:17175027 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
JBrowse link
G Doc2a double C2 domain alpha increases expression EXP manganese chloride results in increased expression of DOC2A mRNA CTD PMID:28801915 NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP manganese chloride results in decreased expression of DPEP1 mRNA CTD PMID:28801915 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Dpep2 dipeptidase 2 increases expression EXP manganese chloride results in increased expression of DPEP2 mRNA CTD PMID:28801915 NCBI chr19:33,883,557...33,896,487
Ensembl chr19:33,885,478...33,891,954
JBrowse link
G Dph1 diphthamide biosynthesis 1 increases expression EXP manganese chloride results in increased expression of DPH1 mRNA CTD PMID:28801915 NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO manganese chloride results in increased expression of DPP4 mRNA CTD PMID:17175027 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression
increases expression
ISO
EXP
manganese chloride results in decreased expression of DPYSL3 mRNA
manganese chloride results in increased expression of DPYSL3 mRNA
CTD PMID:22407947 PMID:25698507 PMID:28801915 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO manganese chloride results in decreased expression of DR1 mRNA CTD PMID:17175027 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
JBrowse link
G Drd1 dopamine receptor D1 decreases expression
multiple interactions
increases expression
ISO
EXP
manganese chloride results in decreased expression of DRD1 protein
Melatonin inhibits the reaction [manganese chloride results in decreased expression of DRD1 protein]
manganese chloride results in increased expression of DRD1
[manganese chloride co-treated with Iron deficiency] results in decreased expression of DRD1 protein
CTD PMID:22479410 PMID:23458069 PMID:23604964 PMID:24969583 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
increases expression
decreases expression
EXP
ISO
[manganese chloride co-treated with Iron deficiency] results in increased expression of DRD2 protein; manganese chloride inhibits the reaction [DRD2 protein binds to Spiperone]
manganese chloride results in increased expression of DRD2; manganese chloride results in increased expression of DRD2 protein; manganese chloride results in increased expression of DRD2 protein alternative form
manganese chloride results in decreased expression of DRD2 protein
Melatonin promotes the reaction [manganese chloride results in decreased expression of DRD2 protein]
CTD PMID:21484877 PMID:22479410 PMID:23458069 PMID:24969583 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dscaml1 DS cell adhesion molecule-like 1 increases expression EXP manganese chloride results in increased expression of DSCAML1 mRNA CTD PMID:26745496 NCBI chr 8:45,740,298...46,057,322
Ensembl chr 8:45,740,298...46,057,320
JBrowse link
G Dspp dentin sialophosphoprotein increases expression ISO manganese chloride results in increased expression of DSPP mRNA CTD PMID:17175027 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 increases expression EXP manganese chloride results in increased expression of DTX1 mRNA CTD PMID:28801915 NCBI chr12:35,849,647...35,880,835
Ensembl chr12:35,849,617...35,880,838
JBrowse link
G Dusp13b dual specificity phosphatase 13B increases expression EXP manganese chloride results in increased expression of DUSP13B mRNA CTD PMID:28801915 NCBI chr15:2,567,432...2,575,105
Ensembl chr15:2,533,547...2,575,539
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression EXP manganese chloride results in increased expression of DUSP2 mRNA CTD PMID:28801915 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression EXP manganese chloride results in increased expression of DUSP4 mRNA CTD PMID:28801915 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp5 dual specificity phosphatase 5 increases expression
increases methylation
EXP manganese chloride results in increased expression of DUSP5 mRNA
manganese chloride results in increased methylation of DUSP5 gene
CTD PMID:28801915 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases methylation
increases expression
EXP manganese chloride results in increased methylation of DUSP6 gene
manganese chloride results in increased expression of DUSP6 mRNA
CTD PMID:28801915 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dynlt4 dynein light chain Tctex-type 4 increases expression EXP manganese chloride results in increased expression of DYNLT4 mRNA CTD PMID:28801915 NCBI chr 5:130,605,437...130,607,224
Ensembl chr 5:130,605,399...130,607,666
JBrowse link
G Eaf2 ELL associated factor 2 increases expression
increases methylation
EXP manganese chloride results in increased expression of EAF2 mRNA
manganese chloride results in increased methylation of EAF2 gene
CTD PMID:28801915 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ebi3 Epstein-Barr virus induced 3 increases expression EXP manganese chloride results in increased expression of EBI3 mRNA CTD PMID:28801915 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544
JBrowse link
G Ecrg4 ECRG4 augurin precursor decreases expression EXP manganese chloride results in decreased expression of ECRG4 mRNA CTD PMID:28801915 NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595
JBrowse link
G Edn1 endothelin 1 decreases expression EXP manganese chloride results in decreased expression of EDN1 mRNA CTD PMID:28801915 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfl7 EGF-like-domain, multiple 7 increases expression ISO manganese chloride results in increased expression of EGFL7 mRNA CTD PMID:17467022 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases activity
increases expression
ISO
EXP
[manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein
manganese chloride results in increased activity of EGFR protein
manganese chloride results in increased expression of EGFR mRNA
CTD PMID:2354210 PMID:28801915 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression EXP manganese chloride results in increased expression of EGLN3 mRNA CTD PMID:28801915 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Egr1 early growth response 1 increases expression EXP
ISO
manganese chloride results in increased expression of EGR1 mRNA CTD PMID:28801915 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression ISO
EXP
manganese chloride results in increased expression of EGR2 mRNA CTD PMID:28801915 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Egr3 early growth response 3 increases expression EXP manganese chloride results in increased expression of EGR3 mRNA CTD PMID:28801915 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Eif1ad eukaryotic translation initiation factor 1A domain containing increases expression EXP manganese chloride results in increased expression of EIF1AD mRNA CTD PMID:28801915 NCBI chr 1:202,674,362...202,679,662
Ensembl chr 1:202,674,185...202,679,658
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions EXP manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein] CTD PMID:23934647 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of EIF2AK2 protein] CTD PMID:32574669 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
increases expression
EXP [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2AK3 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]; manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]
manganese chloride results in increased phosphorylation of EIF2AK3 protein
manganese chloride results in increased expression of EIF2AK3 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
ISO
EXP
manganese chloride results in increased phosphorylation of EIF2S1 protein
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2S1 protein; manganese chloride promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2S1 protein]
CTD PMID:23764342 PMID:23948121 PMID:32574669 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
ISO corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of EIF4EBP1 protein] CTD PMID:30578841 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO manganese chloride results in decreased expression of ELF1 mRNA CTD PMID:17175027 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
JBrowse link
G Elk3 ETS transcription factor ELK3 increases expression ISO manganese chloride results in increased expression of ELK3 mRNA CTD PMID:17467022 NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084
JBrowse link
G Elmod3 ELMO domain containing 3 increases expression EXP manganese chloride results in increased expression of ELMOD3 mRNA CTD PMID:28801915 NCBI chr 4:104,614,665...104,653,122
Ensembl chr 4:104,614,676...104,653,053
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP manganese chloride results in decreased expression of ELOVL6 mRNA CTD PMID:28801915 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Eml2 EMAP like 2 increases expression ISO manganese chloride results in increased expression of EML2 mRNA CTD PMID:17175027 NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression EXP manganese chloride results in decreased expression of ENC1 mRNA CTD PMID:28801915 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Eng endoglin increases expression ISO manganese chloride results in increased expression of ENG mRNA CTD PMID:17467022 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Eno2 enolase 2 increases expression
decreases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of ENO2 mRNA
manganese chloride results in decreased expression of ENO2 protein
Melatonin inhibits the reaction [manganese chloride results in decreased expression of ENO2 protein]
CTD PMID:22281203 PMID:24969583 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Eomes eomesodermin decreases expression ISO manganese chloride results in decreased expression of EOMES mRNA; manganese chloride results in decreased expression of EOMES protein CTD PMID:25698507 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO manganese chloride results in increased expression of EPAS1 mRNA CTD PMID:17467022 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epdr1 ependymin related 1 increases expression EXP manganese chloride results in increased expression of EPDR1 mRNA CTD PMID:28801915 NCBI chr17:45,333,932...45,358,597
Ensembl chr17:45,333,956...45,358,594
JBrowse link
G Epha2 Eph receptor A2 increases expression EXP manganese chloride results in increased expression of EPHA2 mRNA CTD PMID:28801915 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Epha4 Eph receptor A4 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of EPHA4 gene
manganese chloride results in decreased expression of EPHA4 mRNA
CTD PMID:28801915 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression ISO manganese chloride results in increased expression of ERAP1 mRNA CTD PMID:17467022 NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO manganese chloride results in decreased expression of ERCC6L mRNA CTD PMID:17175027 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756
JBrowse link
G Ereg epiregulin increases expression ISO manganese chloride results in increased expression of EREG mRNA CTD PMID:17175027 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Erich1 glutamate-rich 1 increases expression ISO manganese chloride results in increased expression of ERICH1 mRNA CTD PMID:17175027 NCBI chr16:75,501,322...75,569,129
Ensembl chr16:75,501,384...75,569,128
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases phosphorylation
EXP SNCA protein promotes the reaction [manganese chloride results in increased phosphorylation of ERN1 protein] CTD PMID:23934647 PMID:25732873 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression EXP manganese chloride results in increased expression of ERRFI1 mRNA CTD PMID:28801915 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
ISO Estradiol inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of ESR1 protein] CTD PMID:29183790 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Etv3 ETS variant transcription factor 3 increases expression EXP manganese chloride results in increased expression of ETV3 mRNA CTD PMID:28801915 NCBI chr 2:172,965,461...172,980,320
Ensembl chr 2:172,965,588...172,980,314
JBrowse link
G Etv4 ETS variant transcription factor 4 increases expression EXP manganese chloride results in increased expression of ETV4 mRNA CTD PMID:28801915 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression EXP manganese chloride results in increased expression of ETV5 mRNA CTD PMID:28801915 NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215
JBrowse link
G Eva1c eva-1 homolog C increases expression EXP manganese chloride results in increased expression of EVA1C mRNA CTD PMID:28801915 NCBI chr11:30,089,510...30,163,596
Ensembl chr11:30,089,365...30,163,596
JBrowse link
G Exoc6 exocyst complex component 6 decreases expression ISO manganese chloride results in decreased expression of EXOC6 mRNA CTD PMID:17175027 NCBI chr 1:235,314,612...235,457,824
Ensembl chr 1:235,300,369...235,457,015
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 decreases expression ISO manganese chloride results in decreased expression of EYA4 mRNA CTD PMID:17175027 NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression EXP manganese chloride results in increased expression of F2RL1 mRNA CTD PMID:28801915 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fa2h fatty acid 2-hydroxylase increases expression
decreases expression
EXP manganese chloride results in increased expression of FA2H mRNA
manganese chloride results in decreased expression of FA2H mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression EXP manganese chloride results in decreased expression of FADS2 mRNA CTD PMID:28801915 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression EXP manganese chloride results in decreased expression of FAM107A mRNA CTD PMID:26745496 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
JBrowse link
G Fam171b family with sequence similarity 171, member B increases expression EXP manganese chloride results in increased expression of FAM171B mRNA CTD PMID:28801915 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
JBrowse link
G Fam180a family with sequence similarity 180, member A decreases expression EXP manganese chloride results in decreased expression of FAM180A mRNA CTD PMID:26745496 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047
JBrowse link
G Fam210a family with sequence similarity 210, member A increases expression EXP manganese chloride results in increased expression of FAM210A mRNA CTD PMID:28801915 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression EXP manganese chloride results in increased expression of FAM210B mRNA CTD PMID:28801915 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397
JBrowse link
G Fam219a family with sequence similarity 219, member A increases expression EXP manganese chloride results in increased expression of FAM219A mRNA CTD PMID:28801915 NCBI chr 5:56,679,272...56,729,959
Ensembl chr 5:56,680,613...56,729,924
JBrowse link
G Fam227a family with sequence similarity 227, member A increases expression EXP manganese chloride results in increased expression of FAM227A mRNA CTD PMID:28801915 NCBI chr 7:111,174,362...111,216,513
Ensembl chr 7:111,174,362...111,216,483
JBrowse link
G Fam229b family with sequence similarity 229, member B increases expression EXP manganese chloride results in increased expression of FAM229B mRNA CTD PMID:28801915 NCBI chr20:42,538,853...42,552,355
Ensembl chr20:42,538,868...42,552,248
JBrowse link
G Fancf FA complementation group F decreases expression ISO manganese chloride results in decreased expression of FANCF mRNA CTD PMID:17175027 NCBI chr 1:101,449,120...101,451,936
Ensembl chr 1:101,450,389...101,451,923
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP manganese chloride results in increased expression of FAS mRNA CTD PMID:28801915 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression
multiple interactions
EXP manganese chloride results in increased expression of FASLG protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of FASLG protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of FASLG protein]
CTD PMID:21704098 PMID:28378122 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase decreases expression EXP manganese chloride results in decreased expression of FASN mRNA CTD PMID:28801915 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fat2 FAT atypical cadherin 2 increases methylation EXP manganese chloride results in increased methylation of FAT2 gene CTD PMID:28801915 NCBI chr10:39,364,072...39,456,324
Ensembl chr10:39,364,073...39,456,216
JBrowse link
G Fat4 FAT atypical cadherin 4 decreases expression EXP manganese chloride results in decreased expression of FAT4 mRNA CTD PMID:28801915 NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707
JBrowse link
G Fbln2 fibulin 2 increases expression EXP manganese chloride results in increased expression of FBLN2 mRNA CTD PMID:28801915 NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
JBrowse link
G Fbn1 fibrillin 1 increases expression EXP manganese chloride results in increased expression of FBN1 mRNA CTD PMID:28801915 NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
JBrowse link
G Fbp2 fructose-bisphosphatase 2 increases expression EXP manganese chloride results in increased expression of FBP2 mRNA CTD PMID:28801915 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression EXP manganese chloride results in increased expression of FBXL2 mRNA CTD PMID:28801915 NCBI chr 8:113,916,660...113,965,137
Ensembl chr 8:113,913,373...113,965,066
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP manganese chloride results in increased expression of FBXL4 mRNA CTD PMID:28801915 NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443
JBrowse link
G Fcgr1a Fc gamma receptor 1A decreases expression EXP manganese chloride results in decreased expression of FCGR1A mRNA CTD PMID:26745496 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr3a Fc gamma receptor 3A increases expression EXP manganese chloride results in increased expression of FCGR3A mRNA CTD PMID:28801915 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression EXP manganese chloride results in decreased expression of FDPS mRNA CTD PMID:28801915 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fdps-ps4 farnesyl diphosphate synthase, pseudogene 4 decreases expression EXP manganese chloride results in decreased expression of FDPS-PS4 mRNA CTD PMID:28801915 NCBI chr 8:18,816,786...18,818,020 JBrowse link
G Fdpsl1 farnesyl diphosphate synthase like 1 decreases expression EXP manganese chloride results in decreased expression of RGD1560208 mRNA CTD PMID:28801915 NCBI chr 2:179,060,261...179,060,762 JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression EXP manganese chloride results in increased expression of FEZ1 mRNA CTD PMID:28801915 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 increases expression EXP manganese chloride results in increased expression of FEZ2 mRNA CTD PMID:28801915 NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression
increases methylation
ISO
EXP
manganese chloride results in decreased expression of FGF2 mRNA
manganese chloride results in increased methylation of FGF2 gene
CTD PMID:28801915 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fgf20 fibroblast growth factor 20 increases expression ISO manganese chloride results in increased expression of FGF20 mRNA CTD PMID:28986288 NCBI chr16:52,030,549...52,038,201
Ensembl chr16:52,010,194...52,038,204
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases expression EXP manganese chloride results in decreased expression of FGFBP1 mRNA CTD PMID:26745496 NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP manganese chloride results in decreased expression of FGFR2 mRNA CTD PMID:28801915 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fhip2b FHF complex subunit HOOK interacting protein 2B increases expression EXP manganese chloride results in increased expression of FHIP2B mRNA CTD PMID:28801915 NCBI chr15:45,656,641...45,674,603
Ensembl chr15:45,656,647...45,674,105
JBrowse link
G Fhl1 four and a half LIM domains 1 decreases expression ISO manganese chloride results in decreased expression of FHL1 mRNA CTD PMID:17175027 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO manganese chloride results in increased expression of FIS1 protein CTD PMID:34738708 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
JBrowse link
G Flcn folliculin increases expression ISO manganese chloride results in increased expression of FLCN mRNA CTD PMID:17175027 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 increases expression EXP manganese chloride results in increased expression of FLRT2 mRNA CTD PMID:28801915 NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression ISO manganese chloride results in increased expression of FLT1 mRNA CTD PMID:17467022 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Flvcr2 FLVCR choline and putative heme transporter 2 decreases expression EXP manganese chloride results in decreased expression of FLVCR2 mRNA CTD PMID:28801915 NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression EXP manganese chloride results in increased expression of FMO2 mRNA CTD PMID:28801915 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases methylation
increases expression
EXP manganese chloride results in decreased methylation of FMO5 gene
manganese chloride results in increased expression of FMO5 mRNA
CTD PMID:28801915 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
EXP [Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; [S-ethyl glutathione results in increased abundance of Glutathione] inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; manganese chloride results in increased expression of and results in increased secretion of FN1 protein; Melatonin inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of FN1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA]; phenyl-N-tert-butylnitrone inhibits the reaction [manganese chloride results in increased expression of FN1 mRNA] CTD PMID:19524604 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression
EXP
ISO
manganese chloride results in increased expression of FOS protein
manganese chloride results in decreased expression of FOS protein
CTD PMID:9751194 PMID:25698507 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP manganese chloride results in increased expression of FOSL1 mRNA CTD PMID:28801915 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxn4 forkhead box N4 increases expression EXP manganese chloride results in increased expression of FOXN4 mRNA CTD PMID:26745496 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921
JBrowse link
G Foxp2 forkhead box P2 increases expression ISO manganese chloride results in increased expression of FOXP2 mRNA CTD PMID:17175027 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683
JBrowse link
G Frem3 FRAS1 related extracellular matrix 3 increases expression EXP manganese chloride results in increased expression of FREM3 mRNA CTD PMID:28801915 NCBI chr19:27,308,469...27,366,771
Ensembl chr19:27,308,469...27,366,771
JBrowse link
G Frmd4a FERM domain containing 4A increases expression EXP manganese chloride results in increased expression of FRMD4A mRNA CTD PMID:28801915 NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687
JBrowse link
G Fscn2 fascin actin-bundling protein 2, retinal decreases expression EXP manganese chloride results in decreased expression of FSCN2 mRNA CTD PMID:28801915 NCBI chr10:105,634,783...105,641,322
Ensembl chr10:105,634,783...105,641,322
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
decreases expression
EXP Quercetin inhibits the reaction [manganese chloride results in decreased expression of FSHB protein] CTD PMID:28040552 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fstl3 follistatin like 3 increases expression EXP manganese chloride results in increased expression of FSTL3 mRNA CTD PMID:28801915 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression EXP manganese chloride results in decreased expression of FTH1 mRNA; manganese chloride results in decreased expression of FTH1 protein CTD PMID:15893546 PMID:15922012 PMID:16545456 PMID:16568477 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP manganese chloride results in decreased expression of FTL mRNA CTD PMID:15893546 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Fut1 fucosyltransferase 1 increases expression EXP manganese chloride results in increased expression of FUT1 mRNA CTD PMID:28801915 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
JBrowse link
G Fut2 fucosyltransferase 2 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of FUT2 mRNA
manganese chloride results in increased methylation of FUT2 gene
CTD PMID:28801915 NCBI chr 1:96,119,549...96,139,567
Ensembl chr 1:96,119,371...96,140,360
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 increases expression ISO manganese chloride results in increased expression of FXYD2 mRNA CTD PMID:17175027 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
G G0s2 G0/G1switch 2 increases expression EXP manganese chloride results in increased expression of G0S2 mRNA CTD PMID:28801915 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions
decreases expression
EXP
ISO
[Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of GABBR2 protein
manganese chloride results in decreased expression of GABBR2 mRNA
[manganese chloride results in increased abundance of Manganese] which results in increased expression of GABBR2 protein
CTD PMID:18771689 PMID:32659473 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
decreases expression
increases expression
EXP
ISO
[Iron deficiency co-treated with manganese chloride] results in increased expression of GABRA1 protein
manganese chloride results in decreased expression of GABRA1 mRNA
manganese chloride results in increased expression of GABRA1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of GABRA1 protein
CTD PMID:18771689 PMID:32659473 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 decreases expression EXP manganese chloride results in decreased expression of GABRB3 mRNA CTD PMID:28801915 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 increases expression ISO manganese chloride results in increased expression of GABRG2 mRNA CTD PMID:17175027 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP manganese chloride results in decreased expression of GAD1 mRNA CTD PMID:12106697 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression EXP manganese chloride results in decreased expression of GADD45A mRNA CTD PMID:28801915 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO manganese chloride results in increased expression of GAL mRNA CTD PMID:17175027 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression EXP manganese chloride results in decreased expression of GALE mRNA CTD PMID:28801915 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
JBrowse link
G Garin1b golgi associated RAB2 interactor 1B increases expression EXP manganese chloride results in increased expression of GARIN1B mRNA CTD PMID:28801915 NCBI chr 4:57,915,184...57,938,593
Ensembl chr 4:57,920,790...57,938,591
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 increases methylation
decreases expression
ISO manganese chloride results in increased methylation of GBE1 gene
manganese chloride results in decreased expression of GBE1 mRNA
CTD PMID:27913844 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp5 guanylate binding protein 5 increases methylation
increases expression
EXP manganese chloride results in increased methylation of GBP5 gene
manganese chloride results in increased expression of GBP5 mRNA
CTD PMID:28801915 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase decreases expression EXP manganese chloride results in decreased expression of GCDH mRNA CTD PMID:22281203 NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681
JBrowse link
G Gcfc2 GC-rich sequence DNA-binding factor 2 decreases expression ISO manganese chloride results in decreased expression of GCFC2 mRNA CTD PMID:17175027 NCBI chr 4:114,481,613...114,519,268
Ensembl chr 4:114,481,607...114,519,962
JBrowse link
G Gcgr glucagon receptor decreases expression
increases methylation
EXP manganese chloride results in decreased expression of GCGR mRNA
manganese chloride results in increased methylation of GCGR gene
CTD PMID:28801915 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
JBrowse link
G Gch1 GTP cyclohydrolase 1 decreases expression EXP manganese chloride results in decreased expression of GCH1 mRNA CTD PMID:28801915 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GCLM mRNA CTD PMID:38503349 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdap2 ganglioside-induced differentiation-associated-protein 2 increases expression ISO manganese chloride results in increased expression of GDAP2 mRNA CTD PMID:17175027 NCBI chr 2:187,528,514...187,585,270
Ensembl chr 2:187,528,513...187,585,270
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO manganese chloride results in increased expression of GDF15 mRNA CTD PMID:17175027 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdnf glial cell derived neurotrophic factor increases methylation ISO manganese chloride results in increased methylation of GDNF gene CTD PMID:27913844 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression
multiple interactions
EXP
ISO
manganese chloride results in decreased expression of GFAP protein
manganese chloride results in increased expression of GFAP protein
Melatonin inhibits the reaction [manganese chloride results in increased expression of GFAP protein]
CTD PMID:12009774 PMID:12106697 PMID:24060432 PMID:24969583 PMID:25288107 More... NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP manganese chloride results in decreased expression of GJA1 mRNA CTD PMID:28801915 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression EXP manganese chloride results in decreased expression of GJA5 mRNA CTD PMID:26745496 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gja8 gap junction protein, alpha 8 increases expression EXP manganese chloride results in increased expression of GJA8 mRNA CTD PMID:28801915 NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
JBrowse link
G Gjb5 gap junction protein, beta 5 increases expression EXP manganese chloride results in increased expression of GJB5 mRNA CTD PMID:28801915 NCBI chr 5:139,680,670...139,683,588
Ensembl chr 5:139,680,671...139,683,583
JBrowse link
G Gkn3 gastrokine 3 decreases expression EXP manganese chloride results in decreased expression of GKN3 mRNA CTD PMID:28801915 NCBI chr 4:119,828,859...119,833,924
Ensembl chr 4:119,829,005...119,834,842
JBrowse link
G Gldn gliomedin decreases expression EXP manganese chloride results in decreased expression of GLDN mRNA CTD PMID:26745496 NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196
JBrowse link
G Glis1 GLIS family zinc finger 1 decreases expression EXP manganese chloride results in decreased expression of GLIS1 mRNA CTD PMID:28801915 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression EXP manganese chloride results in increased expression of GLIS2 mRNA CTD PMID:28801915 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578
JBrowse link
G Glt8d2 glycosyltransferase 8 domain containing 2 increases expression EXP manganese chloride results in increased expression of GLT8D2 mRNA CTD PMID:28801915 NCBI chr 7:21,029,534...21,081,081
Ensembl chr 7:21,029,525...21,081,080
JBrowse link
G Glul glutamate-ammonia ligase decreases expression
multiple interactions
EXP manganese chloride results in decreased expression of GLUL mRNA; manganese chloride results in decreased expression of GLUL protein
Riluzole inhibits the reaction [manganese chloride results in decreased expression of and results in decreased activity of GLUL protein]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of GLUL mRNA]
CTD PMID:19615351 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gnb4 G protein subunit beta 4 increases expression EXP manganese chloride results in increased expression of GNB4 mRNA CTD PMID:28801915 NCBI chr 2:115,360,746...115,400,680
Ensembl chr 2:115,364,918...115,400,579
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression
multiple interactions
increases secretion
EXP manganese chloride results in increased expression of GNRH1 mRNA
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; [manganese chloride co-treated with Calcium Chloride] results in increased secretion of GNRH1 protein; [manganese chloride results in increased chemical synthesis of Cyclic GMP] which results in increased secretion of GNRH1 protein; Bicuculline promotes the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Dopamine affects the reaction [manganese chloride results in increased secretion of GNRH1 protein]; gamma-Aminobutyric Acid inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; KT 5823 inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]; Methylene Blue inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]
CTD PMID:17110411 PMID:17290048 PMID:18603625 PMID:21402727 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP manganese chloride results in increased expression of GPNMB mRNA CTD PMID:28801915 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpr18 G protein-coupled receptor 18 decreases expression EXP manganese chloride results in decreased expression of GPR18 mRNA CTD PMID:26745496 NCBI chr15:98,997,427...99,001,177
Ensembl chr15:98,997,259...99,001,470
JBrowse link
G Gpr34 G protein-coupled receptor 34 decreases expression EXP manganese chloride results in decreased expression of GPR34 mRNA CTD PMID:26745496 NCBI chr  X:9,104,829...9,113,796
Ensembl chr  X:9,104,565...9,148,601
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
increases activity
ISO
EXP
Melatonin affects the reaction [manganese chloride results in decreased expression of GPX1 protein]
manganese chloride results in increased activity of GPX1 protein
[Cadmium Chloride co-treated with lead acetate co-treated with manganese chloride] results in increased activity of GPX1 protein
CTD PMID:24969583 PMID:25288107 PMID:27599793 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 increases methylation
decreases expression
ISO
EXP
manganese chloride results in increased methylation of GRIK3 gene
manganese chloride results in decreased expression of GRIK3 mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP manganese chloride results in decreased expression of GRIN1 mRNA; manganese chloride results in decreased expression of GRIN1 protein CTD PMID:20175136 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP manganese chloride results in decreased expression of GRIN2A mRNA; manganese chloride results in decreased expression of GRIN2A protein CTD PMID:20175136 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP manganese chloride results in decreased expression of GRIN2B mRNA; manganese chloride results in decreased expression of GRIN2B protein CTD PMID:20175136 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsdmdl1 gasdermin D like 1 increases expression EXP manganese chloride results in increased expression of GSDMDL1 mRNA CTD PMID:28801915 NCBI chr 7:95,620,052...95,630,546
Ensembl chr 7:95,620,061...95,630,532
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity
decreases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased phosphorylation of GSK3B protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased activity of GSK3B protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; Lithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]; manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:20937724 PMID:24464479 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gskip GSK3B interacting protein increases expression EXP manganese chloride results in increased expression of GSKIP mRNA CTD PMID:28801915 NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100
JBrowse link
G Gspt2 G1 to S phase transition 2 decreases expression EXP manganese chloride results in decreased expression of GSPT2 mRNA CTD PMID:28801915 NCBI chr  X:59,587,237...59,589,758
Ensembl chr  X:59,587,276...59,594,162
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of GSR mRNA
manganese chloride results in decreased expression of GSR protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of GSR protein; Melatonin affects the reaction [manganese chloride results in decreased expression of GSR protein]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of GSR protein]
CTD PMID:17175027 PMID:24969583 PMID:25288107 PMID:32445656 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GSTO1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GSTO1 protein CTD PMID:38129942 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 decreases expression ISO manganese chloride results in decreased expression of GTF2H1 mRNA CTD PMID:17175027 NCBI chr 1:97,321,417...97,349,455
Ensembl chr 1:97,321,394...97,349,455
JBrowse link
G H1f1 H1.1 linker histone, cluster member decreases expression EXP manganese chloride results in decreased expression of H1F1 mRNA CTD PMID:28801915 NCBI chr17:41,366,268...41,367,011
Ensembl chr17:41,366,268...41,367,011
JBrowse link
G H1f2 H1.2 linker histone, cluster member decreases expression EXP manganese chloride results in decreased expression of H1F2 mRNA CTD PMID:28801915 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
JBrowse link
G H2bc8 H2B clustered histone 8 decreases expression EXP manganese chloride results in decreased expression of H2BC8 mRNA CTD PMID:28801915 NCBI chr17:42,708,658...42,709,408 JBrowse link
G H2bu1 H2B.U histone 1 decreases expression EXP manganese chloride results in decreased expression of H2BU1 mRNA CTD PMID:28801915 NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277
JBrowse link
G H3c1 H3 clustered histone 1 decreases expression EXP manganese chloride results in decreased expression of H3C1 mRNA CTD PMID:28801915 NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
Ensembl chr17:41,368,386...41,368,856
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
multiple interactions
EXP
ISO
manganese chloride results in decreased expression of HAMP mRNA
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of HAMP protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of HAMP protein
CTD PMID:20635692 PMID:34590183 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hapln3 hyaluronan and proteoglycan link protein 3 increases expression EXP manganese chloride results in increased expression of HAPLN3 mRNA CTD PMID:28801915 NCBI chr 1:133,046,465...133,064,665
Ensembl chr 1:133,046,467...133,080,177
JBrowse link
G Hat1 histone acetyltransferase 1 decreases expression EXP
ISO
manganese chloride results in decreased expression of HAT1 protein CTD PMID:29155171 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]] CTD PMID:34800614 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP manganese chloride results in increased expression of HDAC2 mRNA CTD PMID:29155171 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac3 histone deacetylase 3 increases expression
multiple interactions
ISO
EXP
manganese chloride results in increased expression of HDAC3 mRNA; manganese chloride results in increased expression of HDAC3 protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]]
CTD PMID:29155171 PMID:34800614 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hdac4 histone deacetylase 4 increases expression ISO
EXP
manganese chloride results in increased expression of HDAC4 mRNA; manganese chloride results in increased expression of HDAC4 protein CTD PMID:29155171 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hdgfl3 HDGF like 3 increases expression EXP manganese chloride results in increased expression of HDGFL3 mRNA CTD PMID:28801915 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
JBrowse link
G Heatr3 HEAT repeat containing 3 increases expression EXP manganese chloride results in increased expression of HEATR3 mRNA CTD PMID:28801915 NCBI chr19:18,892,477...18,930,502
Ensembl chr19:18,893,144...18,930,509
JBrowse link
G Heph hephaestin increases expression ISO manganese chloride results in increased expression of HEPH mRNA CTD PMID:17175027 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980
JBrowse link
G Hexd hexosaminidase D multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of HEXD mRNA CTD PMID:35690225 NCBI chr10:106,479,781...106,498,799
Ensembl chr10:106,480,194...106,498,799
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 increases expression EXP manganese chloride results in increased expression of HEY1 mRNA CTD PMID:28801915 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hfe homeostatic iron regulator multiple interactions
decreases response to substance
ISO HFE gene mutant form inhibits the reaction [manganese chloride results in decreased activity of SOD1 protein]
HFE gene mutant form results in decreased susceptibility to manganese chloride
CTD PMID:25874029 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
decreases hydroxylation
increases stability
decreases degradation
decreases expression
ISO
EXP
manganese chloride results in increased expression of HIF1A mRNA; manganese chloride results in increased expression of HIF1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased degradation of HIF1A protein; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased hydroxylation of HIF1A protein; Ascorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]; HIF1A mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]; Iron inhibits the reaction [manganese chloride results in increased expression of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]; VHL protein affects the reaction [manganese chloride results in increased expression of HIF1A protein]
manganese chloride results in decreased degradation of HIF1A protein
manganese chloride results in decreased expression of HIF1A mRNA
[[manganese chloride results in increased abundance of Manganese] which co-treated with Ethanol] results in increased expression of HIF1A protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of HIF1A protein
CTD PMID:17175027 PMID:17467022 PMID:19074761 PMID:19263519 PMID:20152896 More... NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor decreases expression ISO manganese chloride results in decreased expression of HIF1AN mRNA CTD PMID:17175027 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression EXP manganese chloride results in increased expression of HILPDA mRNA CTD PMID:22281203 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 decreases expression EXP manganese chloride results in decreased expression of HIPK3 mRNA CTD PMID:28801915 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
JBrowse link
G Hist1h2an histone cluster 1, H2an decreases expression EXP manganese chloride results in decreased expression of HIST1H2AN mRNA CTD PMID:28801915 NCBI chr17:41,534,653...41,535,259
Ensembl chr17:41,534,691...41,539,869
JBrowse link
G Hist1h2bc histone cluster 1, H2bc decreases expression EXP manganese chloride results in decreased expression of HIST1H2BC mRNA CTD PMID:28801915 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression EXP manganese chloride results in decreased expression of HIST1H2BQ mRNA CTD PMID:28801915 NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153
JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 decreases expression EXP manganese chloride results in decreased expression of HIST2H2AA2 mRNA CTD PMID:28801915 NCBI chr 2:183,801,308...183,801,891 JBrowse link
G Hist3h2ba histone cluster 3, H2ba decreases expression EXP manganese chloride results in decreased expression of HIST3H2BA mRNA CTD PMID:28801915 NCBI chr10:43,725,836...43,726,465
Ensembl chr10:43,724,930...43,727,107
JBrowse link
G Hmbox1 homeobox containing 1 decreases expression EXP manganese chloride results in decreased expression of HMBOX1 mRNA CTD PMID:28801915 NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323
JBrowse link
G Hmcn2 hemicentin 2 increases expression EXP manganese chloride results in increased expression of HMCN2 mRNA CTD PMID:28801915 NCBI chr 3:14,588,353...14,738,320
Ensembl chr 3:14,588,662...14,738,025
JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions
ISO manganese chloride results in increased expression of HMGB1 mRNA
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]; manganese chloride results in increased expression of and affects the localization of HMGB1 protein
CTD PMID:30578841 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP manganese chloride results in decreased expression of HMGCS2 mRNA CTD PMID:26745496 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 affects response to substance
multiple interactions
increases expression
ISO
EXP
HMOX1 protein affects the susceptibility to manganese chloride
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein; anacardic acid promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 protein]; lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; lactacystin promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]; manganese chloride promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 mRNA]; trichostatin A promotes the reaction [manganese chloride results in increased expression of HMOX1 protein]
HMOX1 protein inhibits the reaction [manganese chloride results in increased abundance of Hydrogen Peroxide]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]; Melatonin inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]
manganese chloride results in increased expression of HMOX1 mRNA; manganese chloride results in increased expression of HMOX1 protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of HMOX1 mRNA
CTD PMID:21107535 PMID:21384399 PMID:21963524 PMID:22281203 PMID:25288107 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO manganese chloride results in decreased expression of HOXB9 mRNA CTD PMID:17175027 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
JBrowse link
G Hoxd4 homeo box D4 increases expression EXP manganese chloride results in increased expression of HOXD4 mRNA CTD PMID:28801915 NCBI chr 3:59,614,464...59,634,042
Ensembl chr 3:59,614,464...59,631,528
JBrowse link
G Hpx hemopexin decreases expression EXP manganese chloride results in decreased expression of HPX mRNA CTD PMID:28801915 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hrh1 histamine receptor H 1 decreases methylation ISO manganese chloride results in decreased methylation of HRH1 gene CTD PMID:27913844 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression
decreases methylation
EXP manganese chloride results in increased expression of HRK mRNA
manganese chloride results in decreased methylation of HRK gene
CTD PMID:28801915 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP manganese chloride results in increased expression of HSD11B1 mRNA CTD PMID:28801915 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions
increases expression
EXP SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 protein]
manganese chloride results in increased expression of HSP90B1 mRNA; manganese chloride results in increased expression of HSP90B1 protein
CTD PMID:23934647 PMID:23948121 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression EXP manganese chloride results in increased expression of HSPA4L mRNA CTD PMID:28801915 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of HSPA5 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 protein]
manganese chloride results in increased expression of HSPA5 mRNA; manganese chloride results in increased expression of HSPA5 protein
CTD PMID:23934647 PMID:23948121 PMID:25732873 PMID:32574669 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 decreases expression EXP manganese chloride results in decreased expression of HSPB8 mRNA CTD PMID:28801915 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression EXP manganese chloride results in increased expression of HTRA1 mRNA CTD PMID:28801915 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Htt huntingtin affects response to substance ISO HTT affects the susceptibility to manganese chloride CTD PMID:22363539 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO
EXP
manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
manganese chloride results in decreased expression of ICAM1 protein
CTD PMID:23329836 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO manganese chloride results in increased expression of ID1 mRNA CTD PMID:17467022 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of ID2 mRNA
manganese chloride results in decreased expression of ID2 mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of IDH3G mRNA CTD PMID:35690225 NCBI chr  X:151,515,244...151,524,175
Ensembl chr  X:151,515,247...151,524,171
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of IFNG protein
manganese chloride promotes the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]]
CTD PMID:16168523 PMID:20798247 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ift70a1 intraflagellar transport 70A1 increases expression EXP manganese chloride results in increased expression of IFT70A1 mRNA CTD PMID:28801915 NCBI chr 3:60,901,896...60,905,350
Ensembl chr 3:60,901,896...60,905,350
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP manganese chloride results in increased expression of IGF1 mRNA CTD PMID:21402727 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression
decreases expression
EXP manganese chloride results in increased expression of IGF1R protein
manganese chloride results in decreased expression of IGF1R mRNA
CTD PMID:19276553 PMID:21402727 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 decreases methylation ISO manganese chloride results in decreased methylation of IGF2 gene CTD PMID:27913844 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igf2r insulin-like growth factor 2 receptor decreases expression EXP manganese chloride results in decreased expression of IGF2R mRNA CTD PMID:19276553 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression EXP manganese chloride results in increased expression of IGFBP5 mRNA CTD PMID:28801915 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Igh-6l1 immunoglobulin heavy chain 6 like 1 increases expression EXP manganese chloride results in increased expression of IGH-6L1 mRNA CTD PMID:28801915 NCBI chr 5:148,516,031...148,517,519 JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO IKBKB gene mutant form results in increased susceptibility to [manganese chloride results in increased abundance of Manganese]
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]; IkK-16 compound inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]
CTD PMID:32692843 PMID:34310962 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il12a interleukin 12A increases expression
multiple interactions
ISO manganese chloride results in increased expression of IL12A mRNA
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
CTD PMID:17175027 PMID:28539244 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
ISO manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]
manganese chloride results in increased expression of [IL12A protein binds to IL12B protein]
manganese chloride results in increased expression of IL12B mRNA
CTD PMID:28539244 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
ISO acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP manganese chloride results in increased expression of IL1A mRNA CTD PMID:25219578 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
decreases expression
EXP
ISO
manganese chloride results in increased expression of IL1B protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein]; Minocycline inhibits the reaction [manganese chloride results in increased expression of IL1B protein]
[Lipopolysaccharides co-treated with manganese chloride] results in increased expression of IL1B protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL1B protein; acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL1B mRNA]
manganese chloride results in decreased expression of IL1B mRNA
[manganese chloride co-treated with SNCA protein] results in increased expression of IL1B mRNA; [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B protein
CTD PMID:15601679 PMID:18836210 PMID:27427241 PMID:28539244 PMID:33314588 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression EXP manganese chloride results in increased expression of IL1R1 mRNA CTD PMID:28801915 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression EXP manganese chloride results in increased expression of IL1R2 mRNA CTD PMID:28801915 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression
increases expression
EXP manganese chloride results in decreased expression of IL1RL1 mRNA
manganese chloride results in increased expression of IL1RL1 mRNA
CTD PMID:26745496 PMID:28801915 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP manganese chloride results in increased expression of IL1RN mRNA CTD PMID:28801915 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression EXP manganese chloride results in increased expression of IL23A mRNA CTD PMID:28801915 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Il36rn interleukin 36 receptor antagonist increases expression EXP manganese chloride results in increased expression of IL36RN mRNA CTD PMID:28801915 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL4 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL4 protein CTD PMID:34018660 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression
increases secretion
ISO
EXP
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL6 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of IL6 protein; Buthionine Sulfoximine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Lipopolysaccharides promotes the reaction [manganese chloride results in increased expression of IL6 protein]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; tin protoporphyrin IX inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]]
manganese chloride results in increased expression of IL6 mRNA
manganese chloride results in increased expression of IL6 mRNA; manganese chloride results in increased expression of IL6 protein
manganese chloride results in decreased expression of IL6 mRNA
manganese chloride results in increased secretion of IL6 protein
manganese chloride promotes the reaction [SNCA protein results in increased expression of IL6 mRNA]
CTD PMID:15601679 PMID:17065364 PMID:19815061 PMID:21963524 PMID:25219578 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il7 interleukin 7 increases expression ISO manganese chloride results in increased expression of IL7 mRNA CTD PMID:17175027 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:31555879 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Insig1 insulin induced gene 1 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of INSIG1 mRNA
manganese chloride results in increased methylation of INSIG1 gene
CTD PMID:28801915 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insr insulin receptor decreases expression
increases phosphorylation
increases expression
EXP manganese chloride results in decreased expression of INSR mRNA
manganese chloride results in increased phosphorylation of INSR protein
manganese chloride results in increased expression of INSR mRNA
CTD PMID:2475105 PMID:19276553 PMID:28801915 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Ints2 integrator complex subunit 2 decreases expression EXP manganese chloride results in decreased expression of INTS2 mRNA CTD PMID:28801915 NCBI chr10:71,031,647...71,079,138
Ensembl chr10:71,031,647...71,079,076
JBrowse link
G Iqcg IQ motif containing G increases expression EXP manganese chloride results in increased expression of IQCG mRNA CTD PMID:28801915 NCBI chr11:67,730,117...67,771,170
Ensembl chr11:67,730,247...67,771,168
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression EXP manganese chloride results in increased expression of IQGAP1 mRNA CTD PMID:28801915 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Ireb2 iron responsive element binding protein 2 decreases activity
increases activity
EXP manganese chloride results in decreased activity of IREB2 protein
manganese chloride results in increased activity of IREB2 protein
CTD PMID:15893546 PMID:16568477 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611
JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression EXP manganese chloride results in decreased expression of IRF2 mRNA CTD PMID:28801915 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
JBrowse link
G Ism1 isthmin 1 increases expression EXP manganese chloride results in increased expression of ISM1 mRNA CTD PMID:28801915 NCBI chr 3:127,023,296...127,102,228
Ensembl chr 3:127,021,865...127,101,894
JBrowse link
G Itga10 integrin subunit alpha 10 increases expression EXP manganese chloride results in increased expression of ITGA10 mRNA CTD PMID:28801915 NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein] CTD PMID:20971947 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO manganese chloride results in increased expression of ITGA3 mRNA CTD PMID:17175027 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itga8 integrin subunit alpha 8 increases expression
increases methylation
EXP manganese chloride results in increased expression of ITGA8 mRNA
manganese chloride results in increased methylation of ITGA8 gene
CTD PMID:28801915 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Itgam integrin subunit alpha M increases expression EXP manganese chloride results in increased expression of ITGAM protein CTD PMID:12106697 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]; Wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]
manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]; manganese chloride results in increased activity of [ITGB3 protein binds to ITGA2B protein]
CTD PMID:15213856 PMID:20971947 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itgb5 integrin subunit beta 5 increases expression ISO manganese chloride results in increased expression of ITGB5 mRNA CTD PMID:17175027 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itgb6 integrin subunit beta 6 decreases methylation
increases methylation
increases expression
ISO
EXP
manganese chloride results in decreased methylation of ITGB6 gene
manganese chloride results in increased methylation of ITGB6 gene
manganese chloride results in increased expression of ITGB6 mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO manganese chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO manganese chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
EXP manganese chloride results in increased expression of and results in increased phosphorylation of JUN protein; pyrazolanthrone inhibits the reaction [manganese chloride results in increased phosphorylation of JUN protein] CTD PMID:9751194 PMID:15342272 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 increases expression EXP manganese chloride results in increased expression of KCNG1 mRNA CTD PMID:28801915 NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
JBrowse link
G Kcnh4 potassium voltage-gated channel subfamily H member 4 decreases expression EXP manganese chloride results in decreased expression of KCNH4 mRNA CTD PMID:28801915 NCBI chr10:85,668,332...85,688,166
Ensembl chr10:85,668,337...85,688,158
JBrowse link
G Kcnh6 potassium voltage-gated channel subfamily H member 6 increases expression EXP manganese chloride results in increased expression of KCNH6 mRNA CTD PMID:28801915 NCBI chr10:90,949,240...90,970,746
Ensembl chr10:90,949,846...90,970,701
JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 increases expression ISO manganese chloride results in increased expression of KCNIP3 mRNA CTD PMID:17175027 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ11 protein CTD PMID:32659473 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression ISO manganese chloride results in increased expression of KCNJ3 mRNA CTD PMID:17175027 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of KCNJ8 protein CTD PMID:32659473 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 decreases expression EXP manganese chloride results in decreased expression of KCNK12 mRNA CTD PMID:28801915 NCBI chr 6:6,740,147...6,790,664
Ensembl chr 6:6,739,991...6,790,661
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 increases expression EXP manganese chloride results in increased expression of KCNQ1 mRNA CTD PMID:28801915 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 increases expression EXP manganese chloride results in increased expression of KCNQ2 mRNA CTD PMID:28801915 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 affects expression
multiple interactions
ISO manganese chloride affects the expression of KEAP1 protein
Melatonin affects the reaction [manganese chloride affects the expression of KEAP1 protein]
CTD PMID:25288107 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kera keratocan increases expression EXP manganese chloride results in increased expression of KERA mRNA CTD PMID:26745496 NCBI chr 7:32,397,382...32,404,837
Ensembl chr 7:32,397,382...32,404,837
JBrowse link
G Kiaa1671 KIAA1671 homolog increases expression EXP manganese chloride results in increased expression of KIAA1671 mRNA CTD PMID:28801915 NCBI chr12:43,409,479...43,552,152
Ensembl chr12:43,411,069...43,552,157
JBrowse link
G Kif3b kinesin family member 3B increases expression EXP manganese chloride results in increased expression of KIF3B mRNA CTD PMID:28801915 NCBI chr 3:141,758,466...141,798,012
Ensembl chr 3:141,758,466...141,797,963
JBrowse link
G Kif5c kinesin family member 5C increases expression EXP manganese chloride results in increased expression of KIF5C mRNA CTD PMID:28801915 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
JBrowse link
G Kiss1r KISS1 receptor increases expression EXP manganese chloride results in increased expression of KISS1R mRNA CTD PMID:28801915 NCBI chr 7:9,785,135...9,790,283
Ensembl chr 7:9,785,135...9,788,793
JBrowse link
G Klf2 KLF transcription factor 2 increases expression EXP manganese chloride results in increased expression of KLF2 mRNA CTD PMID:28801915 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Klf4 KLF transcription factor 4 increases expression ISO manganese chloride results in increased expression of KLF4 mRNA CTD PMID:17175027 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klf5 KLF transcription factor 5 decreases expression
increases expression
decreases methylation
ISO
EXP
manganese chloride results in decreased expression of KLF5 mRNA
manganese chloride results in increased expression of KLF5 mRNA
manganese chloride results in decreased methylation of KLF5 gene
CTD PMID:17467022 PMID:28801915 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf9 KLF transcription factor 9 decreases expression ISO manganese chloride results in decreased expression of KLF9 mRNA CTD PMID:17175027 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Klhdc8a kelch domain containing 8A increases expression EXP manganese chloride results in increased expression of KLHDC8A mRNA CTD PMID:28801915 NCBI chr13:43,735,702...43,744,277
Ensembl chr13:43,736,192...43,744,277
JBrowse link
G Kng1 kininogen 1 decreases expression EXP manganese chloride results in decreased expression of KNG1 mRNA CTD PMID:28801915 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
JBrowse link
G Krt7 keratin 7 increases expression EXP manganese chloride results in increased expression of KRT7 mRNA CTD PMID:28801915 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt76 keratin 76 increases expression EXP manganese chloride results in increased expression of KRT76 mRNA CTD PMID:28801915 NCBI chr 7:133,016,990...133,025,475
Ensembl chr 7:133,016,992...133,025,496
JBrowse link
G Krt79 keratin 79 decreases expression EXP manganese chloride results in decreased expression of KRT79 mRNA CTD PMID:28801915 NCBI chr 7:133,056,710...133,067,750
Ensembl chr 7:133,056,709...133,067,705
JBrowse link
G Krt81 keratin 81 increases expression EXP manganese chloride results in increased expression of KRT81 mRNA CTD PMID:28801915 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170
JBrowse link
G Krt87 keratin 87 increases expression EXP manganese chloride results in increased expression of KRT83 mRNA CTD PMID:28801915 NCBI chr 7:132,547,388...132,555,005
Ensembl chr 7:132,548,141...132,554,978
JBrowse link
G Krtap1-1 keratin associated protein 1-1 increases expression EXP manganese chloride results in increased expression of KRTAP1-3 mRNA CTD PMID:28801915 NCBI chr10:84,545,765...84,546,331
Ensembl chr10:84,545,580...84,546,354
JBrowse link
G Lacc1 laccase domain containing 1 increases expression EXP manganese chloride results in increased expression of LACC1 mRNA CTD PMID:28801915 NCBI chr15:52,390,267...52,407,630
Ensembl chr15:52,395,183...52,407,545
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 protein; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 mRNA]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP1 protein] CTD PMID:31690173 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LAMP2 protein CTD PMID:31690173 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression EXP manganese chloride results in increased expression of LCAT mRNA CTD PMID:28801915 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases expression EXP manganese chloride results in increased expression of LDLRAD4 mRNA CTD PMID:28801915 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lgals3 galectin 3 increases expression EXP manganese chloride results in increased expression of LGALS3 mRNA CTD PMID:28801915 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression EXP manganese chloride results in increased expression of LGI4 mRNA CTD PMID:28801915 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 decreases expression EXP manganese chloride results in decreased expression of LGR4 mRNA CTD PMID:28801915 NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression
EXP Quercetin inhibits the reaction [manganese chloride results in decreased expression of LHB protein] CTD PMID:28040552 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhfpl2 LHFPL tetraspan subfamily member 2 increases expression EXP manganese chloride results in increased expression of LHFPL2 mRNA CTD PMID:28801915 NCBI chr 2:25,281,771...25,428,128
Ensembl chr 2:25,281,901...25,427,950
JBrowse link
G Lhx1 LIM homeobox 1 decreases expression EXP manganese chloride results in decreased expression of LHX1 mRNA CTD PMID:28801915 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression EXP manganese chloride results in increased expression of LIF mRNA CTD PMID:28801915 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lman2 lectin, mannose-binding 2 increases expression ISO manganese chloride results in increased expression of LMAN2 mRNA CTD PMID:17175027 NCBI chr17:9,269,236...9,286,923
Ensembl chr17:9,269,022...9,287,265
JBrowse link
G Lmod2 leiomodin 2 decreases expression EXP manganese chloride results in decreased expression of LMOD2 mRNA CTD PMID:28801915 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120
JBrowse link
G Lox lysyl oxidase decreases expression EXP manganese chloride results in decreased expression of LOX mRNA CTD PMID:28801915 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpal2 lipoprotein(a) like 2 decreases expression EXP manganese chloride results in decreased expression of LPAL2 mRNA CTD PMID:28801915 NCBI chr 4:165,207,378...165,264,321
Ensembl chr 4:165,207,328...165,264,340
JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression EXP manganese chloride results in decreased expression of LPAR1 mRNA CTD PMID:28801915 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 decreases expression EXP manganese chloride results in decreased expression of LPCAT4 mRNA CTD PMID:28801915 NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875
JBrowse link
G Lpin1 lipin 1 decreases expression EXP manganese chloride results in decreased expression of LPIN1 mRNA CTD PMID:28801915 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP manganese chloride results in increased expression of LRAT mRNA CTD PMID:26745496 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
JBrowse link
G Lrp2 LDL receptor related protein 2 decreases expression EXP manganese chloride results in decreased expression of LRP2 mRNA CTD PMID:28801915 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708
JBrowse link
G Lrp8 LDL receptor related protein 8 increases expression ISO manganese chloride results in increased expression of LRP8 mRNA CTD PMID:22407947 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
JBrowse link
G Lrrc10b leucine rich repeat containing 10B increases methylation EXP manganese chloride results in increased methylation of LRRC10B gene CTD PMID:28801915 NCBI chr 1:207,096,471...207,097,699
Ensembl chr 1:207,022,919...207,098,045
JBrowse link
G Lrrc15 leucine rich repeat containing 15 increases expression EXP manganese chloride results in increased expression of LRRC15 mRNA CTD PMID:28801915 NCBI chr11:70,469,817...70,484,268
Ensembl chr11:70,469,804...70,484,267
JBrowse link
G Lrrc8b leucine rich repeat containing 8 VRAC subunit B increases expression EXP manganese chloride results in increased expression of LRRC8B mRNA CTD PMID:28801915 NCBI chr14:4,350,462...4,416,336
Ensembl chr14:4,354,508...4,416,311
JBrowse link
G Lrrk1 leucine-rich repeat kinase 1 increases expression EXP manganese chloride results in increased expression of LRRK1 mRNA CTD PMID:28801915 NCBI chr 1:119,844,360...119,972,885
Ensembl chr 1:119,845,146...119,979,734
JBrowse link
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LSM2 mRNA CTD PMID:35690225 NCBI chr20:3,843,467...3,847,217
Ensembl chr20:3,843,466...3,847,266
JBrowse link
G Ly6g5b lymphocyte antigen 6 family member G5B increases expression EXP manganese chloride results in increased expression of LY6G5B mRNA CTD PMID:28801915 NCBI chr20:3,705,464...3,707,830
Ensembl chr20:3,706,124...3,707,133
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase decreases methylation ISO manganese chloride results in decreased methylation of LYN gene CTD PMID:27913844 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Lypd6b Ly6/Plaur domain containing 6B decreases expression EXP manganese chloride results in decreased expression of LYPD6B mRNA CTD PMID:28801915 NCBI chr 3:34,199,101...34,360,770
Ensembl chr 3:34,199,599...34,360,770
JBrowse link
G Lyrm7 LYR motif containing 7 increases expression EXP manganese chloride results in increased expression of LYRM7 mRNA CTD PMID:28801915 NCBI chr10:38,964,299...38,983,628
Ensembl chr10:38,964,311...38,983,601
JBrowse link
G Lyrm9 LYR motif containing 9 increases expression EXP manganese chloride results in increased expression of LYRM9 mRNA CTD PMID:28801915 NCBI chr10:63,725,718...63,739,772
Ensembl chr10:63,725,743...63,739,772
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 increases expression EXP manganese chloride results in increased expression of MACROD2 mRNA CTD PMID:28801915 NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 increases expression EXP manganese chloride results in increased expression of MADCAM1 mRNA CTD PMID:28801915 NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703
JBrowse link
G Maff MAF bZIP transcription factor F increases expression EXP manganese chloride results in increased expression of MAFF mRNA CTD PMID:28801915 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mageb7 MAGE family member B7 increases expression EXP manganese chloride results in increased expression of MAGEB7 mRNA CTD PMID:28801915 NCBI chr  X:50,965,892...50,969,116
Ensembl chr  X:50,966,208...50,967,245
JBrowse link
G Mall mal, T-cell differentiation protein-like decreases expression EXP manganese chloride results in decreased expression of MALL mRNA CTD PMID:26745496 NCBI chr 3:114,927,897...114,950,840
Ensembl chr 3:114,927,897...114,950,785
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MAP1LC3B mRNA; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of MAP1LC3B mRNA] CTD PMID:31690173 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP manganese chloride results in decreased expression of MAP2 mRNA CTD PMID:28801915 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 decreases methylation ISO manganese chloride results in decreased methylation of MAP2K3 gene CTD PMID:27913844 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 increases phosphorylation EXP manganese chloride results in increased phosphorylation of MAP2K4 protein CTD PMID:9751194 PMID:15342272 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 increases phosphorylation EXP manganese chloride results in increased phosphorylation of MAP3K11 protein CTD PMID:15342272 NCBI chr 1:202,975,353...202,988,655
Ensembl chr 1:202,975,353...202,988,652
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases methylation ISO manganese chloride results in increased methylation of MAP3K7 gene CTD PMID:27913844 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 decreases expression EXP manganese chloride results in decreased expression of MAP4K3 mRNA CTD PMID:28801915 NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334
JBrowse link
G Map7 microtubule-associated protein 7 increases expression EXP manganese chloride results in increased expression of MAP7 mRNA CTD PMID:28801915 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574
JBrowse link
G Map7d2 MAP7 domain containing 2 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of MAP7D2 gene
manganese chloride results in decreased expression of MAP7D2 mRNA
CTD PMID:28801915 NCBI chr  X:35,372,453...35,488,073
Ensembl chr  X:35,372,700...35,488,091
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
decreases phosphorylation
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]
manganese chloride results in increased activity of MAPK1 protein
manganese chloride results in decreased phosphorylation of MAPK1 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression EXP manganese chloride results in increased expression of MAPK11 mRNA CTD PMID:28801915 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
increases expression
ISO manganese chloride results in increased phosphorylation of MAPK14 protein
manganese chloride results in increased expression of MAPK14 mRNA
CTD PMID:15737199 PMID:17467022 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases activity
increases phosphorylation
decreases phosphorylation
EXP
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK3 protein]
manganese chloride results in increased activity of MAPK3 protein
manganese chloride results in decreased phosphorylation of MAPK3 protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK3 protein]
CTD PMID:15010209 PMID:15342272 PMID:16787641 PMID:19084589 PMID:20152896 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity
increases phosphorylation
increases methylation
multiple interactions
ISO
EXP
manganese chloride results in increased activity of MAPK8 protein
manganese chloride results in increased phosphorylation of MAPK8 protein
manganese chloride results in increased methylation of MAPK8 gene
[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein]
CTD PMID:19084589 PMID:20152896 PMID:24324973 PMID:27913844 PMID:30951808 More... NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity
increases phosphorylation
ISO manganese chloride results in increased activity of MAPK9 protein
manganese chloride results in increased phosphorylation of MAPK9 protein
CTD PMID:19084589 PMID:20152896 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
increases phosphorylation
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]; GSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein] CTD PMID:20937724 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Masp1 MBL associated serine protease 1 decreases methylation ISO manganese chloride results in decreased methylation of MASP1 gene CTD PMID:27913844 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G Matn3 matrilin 3 decreases expression EXP manganese chloride results in decreased expression of MATN3 mRNA CTD PMID:28801915 NCBI chr 6:31,748,517...31,768,564
Ensembl chr 6:31,748,474...31,768,101
JBrowse link
G Mbp myelin basic protein increases expression ISO manganese chloride results in increased expression of MBP mRNA CTD PMID:17175027 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like increases expression ISO manganese chloride results in increased expression of MCF2L mRNA CTD PMID:15295902 NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 increases expression ISO manganese chloride results in increased expression of MCHR1 mRNA CTD PMID:17175027 NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression EXP manganese chloride results in decreased expression of MCL1 protein CTD PMID:27107493 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO manganese chloride results in decreased expression of MCM4 mRNA CTD PMID:17175027 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO manganese chloride results in decreased expression of MCM5 mRNA CTD PMID:17175027 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcoln3 mucolipin TRP cation channel 3 increases expression EXP manganese chloride results in increased expression of MCOLN3 mRNA CTD PMID:26745496 NCBI chr 2:235,008,716...235,042,885
Ensembl chr 2:234,966,010...235,043,047
JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MDH1 mRNA CTD PMID:35690225 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP manganese chloride results in increased expression of MDM2 mRNA CTD PMID:28801915 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Me3 malic enzyme 3 increases expression ISO manganese chloride results in increased expression of ME3 mRNA CTD PMID:17175027 NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132
JBrowse link
G Medag mesenteric estrogen-dependent adipogenesis increases expression EXP manganese chloride results in increased expression of MEDAG mRNA CTD PMID:28801915 NCBI chr12:5,613,191...5,634,583
Ensembl chr12:5,613,208...5,634,767
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression
increases methylation
EXP manganese chloride results in decreased expression of MEF2C mRNA
manganese chloride results in increased methylation of MEF2C gene
CTD PMID:28801915 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein increases methylation
increases expression
EXP manganese chloride results in increased methylation of MEPE gene
manganese chloride results in increased expression of MEPE mRNA
CTD PMID:28801915 NCBI chr14:5,420,634...5,432,186
Ensembl chr14:5,420,635...5,432,183
JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions
increases activity
ISO manganese chloride inhibits the reaction [Triazoles results in decreased activity of METAP2 protein]
manganese chloride results in increased activity of METAP2 protein
CTD PMID:12718546 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression
decreases methylation
EXP manganese chloride results in decreased expression of MFAP2 mRNA
manganese chloride results in decreased methylation of MFAP2 gene
CTD PMID:28801915 NCBI chr 5:153,312,068...153,320,266
Ensembl chr 5:153,314,711...153,320,259
JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of MFN2 mRNA; manganese chloride results in decreased expression of MFN2 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in decreased expression of MFN2 protein]]; Resveratrol inhibits the reaction [manganese chloride results in decreased expression of MFN2 protein]
CTD PMID:28539244 PMID:34738708 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 increases expression EXP manganese chloride results in increased expression of MFSD6 mRNA CTD PMID:28801915 NCBI chr 9:48,773,171...48,858,471
Ensembl chr 9:48,773,414...48,858,465
JBrowse link
G Mga MAX dimerization protein MGA increases expression EXP manganese chloride results in increased expression of MGA mRNA CTD PMID:28801915 NCBI chr 3:106,851,216...106,942,908
Ensembl chr 3:106,851,140...106,941,043
JBrowse link
G Mgat1 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression ISO manganese chloride results in increased expression of MGAT1 mRNA CTD PMID:15295902 NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503
JBrowse link
G Mgat5b alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B increases expression EXP manganese chloride results in increased expression of MGAT5B mRNA CTD PMID:28801915 NCBI chr10:102,120,757...102,190,235
Ensembl chr10:102,120,445...102,190,233
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases methylation
increases expression
ISO
EXP
manganese chloride results in increased methylation of MGMT gene
manganese chloride results in increased expression of MGMT mRNA
CTD PMID:27913844 PMID:28801915 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mgp matrix Gla protein increases expression EXP manganese chloride results in increased expression of MGP mRNA CTD PMID:28801915 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression EXP manganese chloride results in decreased expression of MGST1 mRNA CTD PMID:28801915 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression EXP manganese chloride results in increased expression of MGST3 mRNA CTD PMID:28801915 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Mia MIA SH3 domain containing increases expression ISO
EXP
manganese chloride results in increased expression of MIA mRNA CTD PMID:17175027 PMID:28801915 NCBI chr 1:82,473,677...82,476,378
Ensembl chr 1:82,473,678...82,475,370
JBrowse link
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 decreases expression EXP manganese chloride results in decreased expression of MICAL1 mRNA CTD PMID:28801915 NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089
JBrowse link
G Mir107 microRNA 107 decreases expression ISO manganese chloride results in decreased expression of MIR107 mRNA CTD PMID:28986288 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
JBrowse link
G Mir125b1 microRNA 125b-1 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR125B1 mRNA CTD PMID:31555879 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir134 microRNA 134 increases expression ISO manganese chloride results in increased expression of MIR134 mRNA CTD PMID:28986288 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir139 microRNA 139 decreases expression ISO manganese chloride results in decreased expression of MIR139 mRNA CTD PMID:28986288 NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902
JBrowse link
G Mir143 microRNA 143 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR143 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR143 mRNA CTD PMID:38503349 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir146b microRNA 146b decreases expression ISO manganese chloride results in decreased expression of MIR146B mRNA CTD PMID:28986288 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir150 microRNA 150 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR150 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of MIR150 mRNA CTD PMID:38503349 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
JBrowse link
G Mir221 microRNA 221 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR221 mRNA CTD PMID:38503349 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir298 microRNA 298 decreases expression ISO manganese chloride results in decreased expression of MIR298 mRNA CTD PMID:28986288 NCBI chr 3:163,052,291...163,052,372
Ensembl chr 3:163,052,291...163,052,372
JBrowse link
G Mir29a microRNA 29a decreases expression ISO manganese chloride results in decreased expression of MIR29A mRNA CTD PMID:28986288 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir31 microRNA 31 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR31 mRNA CTD PMID:38503349 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir320a microRNA 320a increases expression ISO manganese chloride results in increased expression of MIR320A mRNA CTD PMID:28986288 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir328 microRNA 328 decreases expression ISO manganese chloride results in decreased expression of MIR328 mRNA CTD PMID:28986288 NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849
JBrowse link
G Mir409 microRNA 409 decreases expression ISO manganese chloride results in decreased expression of MIR409 mRNA CTD PMID:28986288 NCBI chr 6:128,757,780...128,757,856
Ensembl chr 6:128,757,779...128,757,858
JBrowse link
G Mir433 microRNA 433 decreases expression ISO manganese chloride results in decreased expression of MIR433 mRNA CTD PMID:28986288 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217
JBrowse link
G Mir582 microRNA 582 multiple interactions EXP [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR582 mRNA CTD PMID:31555879 NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651
JBrowse link
G Mir98 microRNA 98 decreases expression ISO manganese chloride results in decreased expression of MIR98 mRNA CTD PMID:28986288 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
G Mir99a microRNA 99a multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MIR99A mRNA CTD PMID:38503349 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
JBrowse link
G Mirlet7b microRNA let-7b increases expression ISO manganese chloride results in increased expression of MIRLET7B mRNA CTD PMID:28986288 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
JBrowse link
G Mmab metabolism of cobalamin associated B decreases expression EXP manganese chloride results in decreased expression of MMAB mRNA CTD PMID:28801915 NCBI chr12:42,159,109...42,172,518
Ensembl chr12:42,159,089...42,172,490
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP manganese chloride results in increased expression of MMP13 mRNA CTD PMID:26745496 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of MMP14 mRNA
manganese chloride results in increased methylation of MMP14 gene
CTD PMID:28801915 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp24 matrix metallopeptidase 24 increases expression EXP manganese chloride results in increased expression of MMP24 mRNA CTD PMID:28801915 NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression EXP manganese chloride results in increased expression of MMP3 mRNA CTD PMID:26745496 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; manganese chloride results in increased expression of and results in increased secretion of MMP9 protein; resveratrol inhibits the reaction [manganese chloride results in increased expression of and results in increased secretion of MMP9 protein]; resveratrol inhibits the reaction [manganese chloride results in increased expression of MMP9 mRNA] CTD PMID:23811825 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression EXP manganese chloride results in decreased expression of IFI204 mRNA CTD PMID:28801915 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
JBrowse link
G Mob3b MOB kinase activator 3B increases expression EXP manganese chloride results in increased expression of MOB3B mRNA CTD PMID:28801915 NCBI chr 5:49,546,254...49,737,934
Ensembl chr 5:49,545,815...49,737,934
JBrowse link
G Mon2 MON2 homolog, regulator of endosome-to-Golgi trafficking decreases expression EXP manganese chloride results in decreased expression of MON2 mRNA CTD PMID:28801915 NCBI chr 7:58,649,378...58,728,102
Ensembl chr 7:58,651,075...58,728,064
JBrowse link
G Mpc1l mitochondrial pyruvate carrier 1-like increases expression EXP manganese chloride results in increased expression of MPC1L mRNA CTD PMID:28801915 NCBI chr  X:10,146,274...10,147,145
Ensembl chr  X:10,146,293...10,147,145
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
ISO
EXP
diphenyleneiodonium inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]; manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Sodium Azide inhibits the reaction [manganese chloride promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased activity of MPO protein]]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of MPO protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of MPO protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of MPO protein]
CTD PMID:22906169 PMID:28040552 PMID:30844427 PMID:33314588 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mpp3 MAGUK p55 scaffold protein 3 increases expression EXP manganese chloride results in increased expression of MPP3 mRNA CTD PMID:28801915 NCBI chr10:86,945,705...86,975,261
Ensembl chr10:86,945,714...86,974,737
JBrowse link
G Mrps10 mitochondrial ribosomal protein S10 decreases expression EXP manganese chloride results in decreased expression of MRPS10 mRNA CTD PMID:28801915 NCBI chr 9:13,614,897...13,624,819
Ensembl chr 9:13,614,897...13,624,779
JBrowse link
G Ms4a6a membrane spanning 4-domains A6A increases expression EXP manganese chloride results in increased expression of MS4A6A mRNA CTD PMID:28801915 NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
JBrowse link
G Msh5 mutS homolog 5 increases expression EXP manganese chloride results in increased expression of MSH5 mRNA CTD PMID:28801915 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO manganese chloride results in decreased expression of MSH6 mRNA CTD PMID:17175027 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Msx2 msh homeobox 2 decreases expression EXP manganese chloride results in decreased expression of MSX2 mRNA CTD PMID:28801915 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Mt1 metallothionein 1 decreases expression EXP manganese chloride results in decreased expression of MT1A mRNA CTD PMID:12387356 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mt3 metallothionein 3 increases expression EXP manganese chloride results in increased expression of MT3 mRNA CTD PMID:28801915 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mta1 metastasis associated 1 increases expression EXP manganese chloride results in increased expression of MTA1 mRNA CTD PMID:28801915 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Mtap methylthioadenosine phosphorylase increases expression EXP manganese chloride results in increased expression of MTAP mRNA CTD PMID:28801915 NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406
JBrowse link
G Mtch2 mitochondrial carrier 2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of MTCH2 mRNA CTD PMID:35690225 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression
increases methylation
EXP manganese chloride results in increased expression of MTHFD2 mRNA
manganese chloride results in increased methylation of MTHFD2 gene
CTD PMID:28801915 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like increases expression EXP manganese chloride results in increased expression of MTHFD2L mRNA CTD PMID:28801915 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
JBrowse link
G Mtm1 myotubularin 1 decreases expression ISO manganese chloride results in decreased expression of MTM1 mRNA CTD PMID:17175027 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860
JBrowse link
G Mtmr10 myotubularin related protein 10 increases expression EXP manganese chloride results in increased expression of MTMR10 mRNA CTD PMID:28801915 NCBI chr 1:117,859,355...117,910,839
Ensembl chr 1:117,859,267...117,910,849
JBrowse link
G Mtmr6 myotubularin related protein 6 decreases expression EXP manganese chloride results in decreased expression of MTMR6 mRNA CTD PMID:28801915 NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
increases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in decreased phosphorylation of MTOR protein
manganese chloride results in increased phosphorylation of MTOR protein
corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of MTOR protein]
CTD PMID:23604964 PMID:30578841 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mxd4 Max dimerization protein 4 decreases expression EXP manganese chloride results in decreased expression of MXD4 mRNA CTD PMID:28801915 NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221
JBrowse link
G Myh13 myosin heavy chain 13 increases expression EXP manganese chloride results in increased expression of MYH13 mRNA CTD PMID:28801915 NCBI chr10:52,012,779...52,068,960
Ensembl chr10:52,009,425...52,068,951
JBrowse link
G Myh2 myosin heavy chain 2 decreases expression EXP manganese chloride results in decreased expression of MYH2 mRNA CTD PMID:26745496 NCBI chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236
JBrowse link
G Mylk2 myosin light chain kinase 2 increases expression EXP manganese chloride results in increased expression of MYLK2 mRNA CTD PMID:28801915 NCBI chr 3:141,376,450...141,388,357
Ensembl chr 3:141,376,691...141,387,728
JBrowse link
G Mylk3 myosin light chain kinase 3 increases expression EXP manganese chloride results in increased expression of MYLK3 mRNA CTD PMID:28801915 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954
JBrowse link
G Myoc myocilin increases methylation EXP manganese chloride results in increased methylation of MYOC gene CTD PMID:28801915 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Myom1 myomesin 1 increases expression
decreases expression
ISO
EXP
manganese chloride results in increased expression of MYOM1 mRNA
manganese chloride results in decreased expression of MYOM1 mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344
JBrowse link
G Myt1l myelin transcription factor 1-like increases expression ISO
EXP
manganese chloride results in increased expression of MYT1L mRNA CTD PMID:17175027 PMID:26745496 NCBI chr 6:46,164,742...46,564,234
Ensembl chr 6:46,428,150...46,561,671
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO manganese chloride results in increased expression of NAMPT mRNA CTD PMID:17175027 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 increases expression EXP manganese chloride results in increased expression of NANOS1 mRNA CTD PMID:28801915 NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730
JBrowse link
G Nat8l N-acetyltransferase 8-like increases expression EXP manganese chloride results in increased expression of NAT8L mRNA CTD PMID:28801915 NCBI chr14:76,756,077...76,762,712
Ensembl chr14:76,756,077...76,763,411
JBrowse link
G Nav2 neuron navigator 2 increases expression EXP manganese chloride results in increased expression of NAV2 mRNA CTD PMID:28801915 NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 increases expression EXP manganese chloride results in increased expression of NCF4 mRNA CTD PMID:28801915 NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389
JBrowse link
G Ndrg2 NDRG family member 2 decreases expression EXP manganese chloride results in decreased expression of NDRG2 mRNA CTD PMID:28801915 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase increases expression EXP manganese chloride results in increased expression of NEDD4L mRNA; manganese chloride results in increased expression of NEDD4L protein CTD PMID:20737472 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137
JBrowse link
G Nefh neurofilament heavy chain decreases expression ISO manganese chloride results in decreased expression of NEFH mRNA CTD PMID:15295902 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefl neurofilament light chain decreases expression ISO manganese chloride results in decreased expression of NEFL mRNA CTD PMID:15295902 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
decreases response to substance
affects expression
ISO
EXP
[manganese chloride co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NFE2L2 protein; Melatonin inhibits the reaction [manganese chloride results in increased expression of NFE2L2 protein]
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased activity of NFE2L2 protein]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of NFE2L2 protein]; [anacardic acid results in increased susceptibility to manganese chloride] which results in increased expression of NFE2L2 mRNA; [manganese chloride results in increased susceptibility to trichostatin A] which results in increased expression of NFE2L2 mRNA; anacardic acid inhibits the reaction [manganese chloride results in increased activity of NFE2L2 protein]; lactacystin promotes the reaction [manganese chloride affects the localization of and results in increased activity of NFE2L2 protein]; lactacystin promotes the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; manganese chloride affects the localization of and results in increased activity of NFE2L2 protein; manganese chloride inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of NFE2L2 protein]; manganese chloride promotes the reaction [[NFE2L2 protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]; manganese chloride promotes the reaction [anacardic acid results in increased expression of NFE2L2 mRNA]; manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]; manganese chloride results in increased expression of and affects the localization of NFE2L2 protein; manganese chloride results in increased expression of and results in increased activity of NFE2L2 protein; trichostatin A promotes the reaction [manganese chloride results in increased expression of and results in increased activity of NFE2L2 protein]
NFE2L2 protein results in decreased susceptibility to manganese chloride
manganese chloride affects the expression of NFE2L2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NFE2L2 mRNA
CTD PMID:21107535 PMID:21384399 PMID:21963524 PMID:22154916 PMID:22245093 More... NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfib nuclear factor I/B increases expression ISO manganese chloride results in increased expression of NFIB mRNA CTD PMID:17175027 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479
JBrowse link
G Nfix nuclear factor I X decreases expression ISO manganese chloride results in decreased expression of NFIX mRNA CTD PMID:17175027 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP manganese chloride promotes the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]] CTD PMID:15010209 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha increases degradation
multiple interactions
increases phosphorylation
EXP
ISO
manganese chloride results in increased degradation of NFKBIA protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in increased degradation of NFKBIA protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; Reactive Oxygen Species affects the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]
NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]]; NFKBIA protein affects the reaction [manganese chloride results in increased expression of NOS2 mRNA]; NFKBIA protein affects the reaction [manganese chloride results in increased expression of NOS2 protein]
manganese chloride results in increased phosphorylation of NFKBIA protein
CTD PMID:15010209 PMID:16168523 PMID:22245093 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfyb nuclear transcription factor Y subunit beta decreases expression ISO manganese chloride results in decreased expression of NFYB mRNA CTD PMID:17175027 NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
JBrowse link
G Ngf nerve growth factor increases methylation ISO manganese chloride results in increased methylation of NGF gene CTD PMID:27913844 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor increases methylation ISO manganese chloride results in increased methylation of NGFR gene CTD PMID:27913844 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nhlrc1 NHL repeat containing E3 ubiquitin protein ligase 1 increases expression EXP manganese chloride results in increased expression of NHLRC1 mRNA CTD PMID:28801915 NCBI chr17:17,674,303...17,677,144
Ensembl chr17:17,674,319...17,677,148
JBrowse link
G Niban1 niban apoptosis regulator 1 decreases expression EXP manganese chloride results in decreased expression of NIBAN1 mRNA CTD PMID:28801915 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nim1k NIM1 serine/threonine protein kinase decreases expression EXP manganese chloride results in decreased expression of NIM1K mRNA CTD PMID:28801915 NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762
JBrowse link
G Nipal3 NIPA-like domain containing 3 increases expression EXP manganese chloride results in increased expression of NIPAL3 mRNA CTD PMID:28801915 NCBI chr 5:147,687,310...147,725,838
Ensembl chr 5:147,685,288...147,726,351
JBrowse link
G Nog noggin increases expression ISO manganese chloride results in increased expression of NOG mRNA CTD PMID:15295902 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Nol6 nucleolar protein 6 increases expression EXP manganese chloride results in increased expression of NOL6 mRNA CTD PMID:28801915 NCBI chr 5:56,259,919...56,270,540
Ensembl chr 5:56,260,830...56,270,336
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO [Plant Extracts co-treated with manganese chloride] affects the expression of NOS1 protein CTD PMID:26064043 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
affects response to substance
ISO
EXP
[manganese chloride results in increased abundance of Manganese] which results in increased expression of NOS2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of NOS2 protein; [N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased chemical synthesis of Reactive Oxygen Species]; [N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Estradiol inhibits the reaction [manganese chloride results in increased expression of NOS2 mRNA]; Estradiol inhibits the reaction [manganese chloride results in increased expression of NOS2 protein]; manganese chloride promotes the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]]; NFKBIA protein affects the reaction [manganese chloride results in increased expression of NOS2 mRNA]; NFKBIA protein affects the reaction [manganese chloride results in increased expression of NOS2 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
manganese chloride results in increased expression of NOS2 mRNA; manganese chloride results in increased expression of NOS2 protein
manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Minocycline inhibits the reaction [manganese chloride results in increased expression of NOS2 protein]; Silymarin inhibits the reaction [manganese chloride results in increased expression of NOS2 mRNA]
NOS2 protein affects the susceptibility to manganese chloride
manganese chloride results in increased expression of and results in increased activity of NOS2 protein; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased activity of NOS2 protein]
CTD PMID:15010209 PMID:15601679 PMID:16168523 PMID:18836210 PMID:19442826 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO [Plant Extracts co-treated with manganese chloride] affects the expression of NOS3 protein CTD PMID:26064043 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nostrin nitric oxide synthase trafficking increases expression EXP manganese chloride results in increased expression of NOSTRIN mRNA CTD PMID:28801915 NCBI chr 3:53,904,746...53,970,995
Ensembl chr 3:53,904,827...53,970,988
JBrowse link
G Notch4 notch receptor 4 decreases expression ISO manganese chloride results in decreased expression of NOTCH4 mRNA CTD PMID:17175027 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Npas2 neuronal PAS domain protein 2 decreases expression EXP manganese chloride results in decreased expression of NPAS2 mRNA CTD PMID:28511934 NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
JBrowse link
G Nphp1 nephrocystin 1 increases expression EXP manganese chloride results in increased expression of NPHP1 mRNA CTD PMID:28801915 NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234
JBrowse link
G Nppa natriuretic peptide A decreases expression ISO manganese chloride results in decreased expression of NPPA mRNA CTD PMID:17175027 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nptx2 neuronal pentraxin 2 increases expression EXP manganese chloride results in increased expression of NPTX2 mRNA CTD PMID:28801915 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345
JBrowse link
G Nptxr neuronal pentraxin receptor increases expression EXP manganese chloride results in increased expression of NPTXR mRNA CTD PMID:28801915 NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects expression
decreases expression
multiple interactions
increases expression
ISO
EXP
manganese chloride affects the expression of NQO1 protein
manganese chloride results in decreased expression of NQO1 protein
Melatonin affects the reaction [manganese chloride affects the expression of NQO1 protein]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of NQO1 protein]
manganese chloride results in increased expression of NQO1 mRNA
CTD PMID:24969583 PMID:25288107 PMID:28801915 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP manganese chloride results in increased expression of NR1D1 mRNA CTD PMID:28511934 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP manganese chloride results in increased expression of NR1D2 mRNA CTD PMID:28801915 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr6a1 nuclear receptor subfamily 6, group A, member 1 increases expression EXP manganese chloride results in increased expression of NR6A1 mRNA CTD PMID:28801915 NCBI chr 3:22,495,109...22,683,132
Ensembl chr 3:22,496,943...22,683,131
JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein increases expression EXP manganese chloride results in increased expression of NRARP mRNA CTD PMID:28801915 NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133
JBrowse link
G Nrep neuronal regeneration related protein increases expression EXP manganese chloride results in increased expression of NREP mRNA CTD PMID:28801915 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
affects expression
EXP Hemin inhibits the reaction [manganese chloride affects the expression of NRF1 protein] CTD PMID:30040983 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP manganese chloride results in increased expression of NRG1 mRNA CTD PMID:28801915 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nrg2 neuregulin 2 increases expression ISO manganese chloride results in increased expression of NRG2 mRNA CTD PMID:17175027 NCBI chr18:27,616,542...27,798,505
Ensembl chr18:27,619,661...27,798,505
JBrowse link
G Nrp1 neuropilin 1 increases expression ISO manganese chloride results in increased expression of NRP1 mRNA CTD PMID:17175027 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nrp2 neuropilin 2 increases expression EXP manganese chloride results in increased expression of NRP2 mRNA CTD PMID:28801915 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase increases methylation
decreases expression
ISO manganese chloride results in increased methylation of NSF gene
manganese chloride results in decreased expression of NSF mRNA
CTD PMID:27913844 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
JBrowse link
G Nt5c1b 5'-nucleotidase, cytosolic IB increases expression EXP manganese chloride results in increased expression of NT5C1B mRNA CTD PMID:28801915 NCBI chr 6:33,139,053...33,156,489
Ensembl chr 6:33,139,064...33,156,481
JBrowse link
G Ntf3 neurotrophin 3 multiple interactions ISO NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTF3 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTF3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTF3 protein]
CTD PMID:31676349 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Ntm neurotrimin increases expression EXP manganese chloride results in increased expression of NTM mRNA CTD PMID:28801915 NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595
JBrowse link
G Ntn4 netrin 4 decreases expression EXP manganese chloride results in decreased expression of NTN4 mRNA CTD PMID:28801915 NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 decreases expression ISO manganese chloride results in decreased expression of NTRK2 protein modified form CTD PMID:25698507 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein]
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein]
CTD PMID:31676349 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Nuak1 NUAK family kinase 1 increases expression EXP manganese chloride results in increased expression of NUAK1 mRNA CTD PMID:28801915 NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 decreases expression ISO manganese chloride results in decreased expression of NUCKS1 mRNA CTD PMID:17175027 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229
JBrowse link
G Nudt11 nudix hydrolase 11 multiple interactions ISO manganese chloride promotes the reaction [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] CTD PMID:12121577 NCBI chr  X:16,326,775...16,333,396
Ensembl chr  X:16,326,598...16,333,145
JBrowse link
G Nudt9 nudix hydrolase 9 multiple interactions
increases activity
ISO Dithiothreitol inhibits the reaction [Hydrogen Peroxide promotes the reaction [manganese chloride results in increased activity of NUDT9 protein]]; Hydrogen Peroxide promotes the reaction [manganese chloride results in increased activity of NUDT9 protein] CTD PMID:16860484 NCBI chr14:5,675,376...5,693,332
Ensembl chr14:5,675,382...5,693,142
JBrowse link
G Nup210 nucleoporin 210 increases expression EXP manganese chloride results in increased expression of NUP210 mRNA CTD PMID:28801915 NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874
JBrowse link
G Nxnl1 nucleoredoxin-like 1 increases expression EXP manganese chloride results in increased expression of NXNL1 mRNA CTD PMID:28801915 NCBI chr16:18,270,604...18,279,797
Ensembl chr16:18,262,688...18,279,987
JBrowse link
G Nxph4 neurexophilin 4 increases expression EXP manganese chloride results in increased expression of NXPH4 mRNA CTD PMID:28801915 NCBI chr 7:63,367,758...63,376,579
Ensembl chr 7:63,367,761...63,376,579
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression EXP manganese chloride results in increased expression of OASL mRNA CTD PMID:28801915 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Obsl1 obscurin like cytoskeletal adaptor 1 decreases expression EXP manganese chloride results in decreased expression of OBSL1 mRNA CTD PMID:28801915 NCBI chr 9:76,967,802...76,993,771
Ensembl chr 9:76,974,253...76,993,560
JBrowse link
G Odf1 outer dense fiber of sperm tails 1 decreases expression
decreases methylation
EXP manganese chloride results in decreased expression of ODF1 mRNA
manganese chloride results in decreased methylation of ODF1 gene
CTD PMID:28801915 NCBI chr 7:69,377,427...69,389,662
Ensembl chr 7:69,380,116...69,389,664
JBrowse link
G Olfm1 olfactomedin 1 increases expression ISO manganese chloride results in increased expression of OLFM1 mRNA CTD PMID:17175027 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239
JBrowse link
G Olig1 oligodendrocyte transcription factor 1 increases expression
increases methylation
EXP manganese chloride results in increased expression of OLIG1 mRNA
manganese chloride results in increased methylation of OLIG1 gene
CTD PMID:28801915 NCBI chr11:30,514,379...30,516,521
Ensembl chr11:30,514,379...30,516,521
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of OPA1 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in decreased expression of OPA1 protein]]; Resveratrol inhibits the reaction [manganese chloride results in decreased expression of OPA1 protein]
CTD PMID:34738708 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Or4p18b olfactory receptor family 4 subfamily P member 18B decreases expression EXP manganese chloride results in decreased expression of OR4P18B mRNA CTD PMID:28801915 NCBI chr 3:75,254,003...75,254,953
Ensembl chr 3:75,247,547...75,258,081
JBrowse link
G Or8b54c olfactory receptor family 8 subfamily B member 54C increases expression EXP manganese chloride results in increased expression of OR8B54C mRNA CTD PMID:28801915 NCBI chr 8:38,990,473...38,991,414
Ensembl chr 8:38,988,215...38,995,222
JBrowse link
G Osr2 odd-skipped related transciption factor 2 decreases expression EXP manganese chloride results in decreased expression of OSR2 mRNA CTD PMID:28801915 NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224
JBrowse link
G P4htm prolyl 4-hydroxylase, transmembrane multiple interactions
decreases activity
ISO [manganese chloride results in decreased activity of P4HTM protein] which results in decreased degradation of HIF1A protein; [manganese chloride results in decreased activity of P4HTM protein] which results in decreased hydroxylation of HIF1A protein; Iron inhibits the reaction [manganese chloride results in decreased activity of P4HTM protein] CTD PMID:19263519 NCBI chr 8:109,274,629...109,292,802
Ensembl chr 8:109,274,626...109,292,473
JBrowse link
G Pabpn1l PABPN1 like decreases expression EXP manganese chloride results in decreased expression of PABPN1L mRNA CTD PMID:28801915 NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366
JBrowse link
G Pappa pappalysin increases expression ISO manganese chloride results in increased expression of PAPPA mRNA CTD PMID:17175027 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
JBrowse link
G Paqr5 progestin and adipoQ receptor family member 5 decreases expression EXP manganese chloride results in decreased expression of PAQR5 mRNA CTD PMID:28801915 NCBI chr 8:62,431,867...62,513,688
Ensembl chr 8:62,431,867...62,513,688
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions
decreases expression
EXP 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride results in decreased expression of PARK7 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased expression of PARK7 protein]
manganese chloride results in decreased expression of PARK7 mRNA; manganese chloride results in decreased expression of PARK7 protein
CTD PMID:20798247 PMID:22245093 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO
EXP
[Plant Extracts co-treated with manganese chloride] affects the cleavage of PARP1 protein
benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [manganese chloride results in increased cleavage of PARP1 protein]
CTD PMID:21704098 PMID:26064043 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 decreases expression EXP manganese chloride results in decreased expression of PBLD1 mRNA CTD PMID:28801915 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pcdh7 protocadherin 7 increases expression ISO manganese chloride results in increased expression of PCDH7 mRNA CTD PMID:17175027 NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051
JBrowse link
G Pcdha6 protocadherin alpha 6 increases expression ISO manganese chloride results in increased expression of PCDHA6 mRNA CTD PMID:17175027 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdhb22 protocadherin beta 22 increases expression EXP manganese chloride results in increased expression of PCDHB22 mRNA CTD PMID:28801915 NCBI chr18:29,223,028...29,229,132
Ensembl chr18:29,223,149...29,225,536
JBrowse link
G Pcdhga1 protocadherin gamma subfamily A, 1 increases expression EXP manganese chloride results in increased expression of PCDHGA1 mRNA CTD PMID:28801915 NCBI chr18:29,487,404...29,667,865
Ensembl chr18:29,487,482...29,492,857
Ensembl chr18:29,487,482...29,492,857
JBrowse link
G Pcdhgb7 protocadherin gamma subfamily B, 7 increases expression EXP manganese chloride results in increased expression of PCDHGB5 mRNA CTD PMID:28801915 NCBI chr18:29,579,129...29,667,868
Ensembl chr18:29,493,954...29,667,868
JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 decreases expression
decreases methylation
EXP manganese chloride results in decreased expression of PCOLCE2 mRNA
manganese chloride results in decreased methylation of PCOLCE2 gene
CTD PMID:28801915 NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114
JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 decreases expression EXP manganese chloride results in decreased expression of PCP4L1 mRNA CTD PMID:28801915 NCBI chr13:83,588,992...83,612,631
Ensembl chr13:83,588,992...83,609,966
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression EXP manganese chloride results in decreased expression of PCSK9 mRNA CTD PMID:28801915 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pde6b phosphodiesterase 6B increases expression EXP manganese chloride results in increased expression of PDE6B mRNA CTD PMID:26745496 NCBI chr14:1,323,310...1,366,450
Ensembl chr14:1,323,310...1,366,450
JBrowse link
G Pde6h phosphodiesterase 6H increases expression EXP manganese chloride results in increased expression of PDE6H mRNA CTD PMID:26745496 NCBI chr 4:169,857,793...169,872,969
Ensembl chr 4:169,857,812...169,872,969
JBrowse link
G Pde7a phosphodiesterase 7A increases expression EXP manganese chloride results in increased expression of PDE7A mRNA CTD PMID:28801915 NCBI chr 2:101,714,767...101,806,853
Ensembl chr 2:101,718,444...101,806,681
JBrowse link
G Pdgfc platelet derived growth factor C decreases expression EXP manganese chloride results in decreased expression of PDGFC mRNA CTD PMID:28801915 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO manganese chloride results in increased expression of PDK1 mRNA CTD PMID:17175027 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression ISO manganese chloride results in decreased expression of PDK4 mRNA CTD PMID:32870474 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdpr pyruvate dehydrogenase phosphatase regulatory subunit increases expression EXP manganese chloride results in increased expression of PDPR mRNA CTD PMID:28801915 NCBI chr19:39,065,226...39,109,695
Ensembl chr19:39,065,157...39,109,688
JBrowse link
G Per1 period circadian regulator 1 decreases expression EXP manganese chloride results in decreased expression of PER1 mRNA CTD PMID:28511934 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Per2 period circadian regulator 2 decreases expression EXP manganese chloride results in decreased expression of PER2 mRNA CTD PMID:28511934 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pgf placental growth factor increases expression ISO
EXP
manganese chloride results in increased expression of PGF mRNA CTD PMID:17175027 PMID:28801915 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Phf10 PHD finger protein 10 increases expression EXP manganese chloride results in increased expression of PHF10 mRNA CTD PMID:28801915 NCBI chr 1:55,952,249...55,968,994
Ensembl chr 1:55,952,253...55,969,038
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression EXP manganese chloride results in increased expression of PHLDA1 mRNA CTD PMID:28801915 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression EXP manganese chloride results in increased expression of PHLDA3 mRNA CTD PMID:28801915 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Phrf1 PHD and ring finger domains 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of PHRF1 mRNA CTD PMID:35690225 NCBI chr 1:196,333,663...196,366,901
Ensembl chr 1:196,333,903...196,366,892
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 decreases expression ISO manganese chloride results in decreased expression of PHTF1 mRNA CTD PMID:17175027 NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 decreases expression
increases methylation
EXP
ISO
manganese chloride results in decreased expression of PIAS1 mRNA
manganese chloride results in increased methylation of PIAS1 gene
CTD PMID:28801915 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905
JBrowse link
G Pink1 PTEN induced kinase 1 decreases expression
increases methylation
ISO manganese chloride results in decreased expression of PINK1 mRNA
manganese chloride results in increased methylation of PINK1 gene
CTD PMID:27913844 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pinlyp phospholipase A2 inhibitor and Ly6/Plaur domain containing increases expression EXP manganese chloride results in increased expression of PINLYP mRNA CTD PMID:28801915 NCBI chr 1:80,134,642...80,140,488
Ensembl chr 1:80,134,643...80,139,996
JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression EXP manganese chloride results in increased expression of PLA2G2A mRNA CTD PMID:28801915 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pla2g2d phospholipase A2, group IID decreases expression
increases methylation
EXP manganese chloride results in decreased expression of PLA2G2D mRNA
manganese chloride results in increased methylation of PLA2G2D gene
CTD PMID:28801915 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 increases expression EXP manganese chloride results in increased expression of PLA2R1 mRNA CTD PMID:28801915 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660
JBrowse link
G Plac8 placenta associated 8 increases expression EXP manganese chloride results in increased expression of PLAC8 mRNA CTD PMID:28801915 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
JBrowse link
G Plce1 phospholipase C, epsilon 1 increases expression ISO manganese chloride results in increased expression of PLCE1 mRNA CTD PMID:17175027 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
JBrowse link
G Pld2 phospholipase D2 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of PLD2 gene
manganese chloride results in decreased expression of PLD2 mRNA
CTD PMID:28801915 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
JBrowse link
G Plek2 pleckstrin 2 increases expression EXP manganese chloride results in increased expression of PLEK2 mRNA CTD PMID:28801915 NCBI chr 6:97,700,123...97,719,417
Ensembl chr 6:97,701,106...97,719,326
JBrowse link
G Plekhh1 pleckstrin homology, MyTH4 and FERM domain containing H1 increases expression EXP manganese chloride results in increased expression of PLEKHH1 mRNA CTD PMID:28801915 NCBI chr 6:97,839,288...97,888,712
Ensembl chr 6:97,839,288...97,888,709
JBrowse link
G Pllp plasmolipin increases expression EXP manganese chloride results in increased expression of PLLP mRNA CTD PMID:28801915 NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892
JBrowse link
G Pln phospholamban decreases expression
increases expression
ISO
EXP
manganese chloride results in decreased expression of PLN mRNA
manganese chloride results in increased expression of PLN mRNA
CTD PMID:17175027 PMID:28801915 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Pls3 plastin 3 decreases expression EXP manganese chloride results in decreased expression of PLS3 mRNA CTD PMID:28801915 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP manganese chloride results in increased expression of PMAIP1 mRNA CTD PMID:28801915 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 increases expression EXP manganese chloride results in increased expression of PMEPA1 mRNA CTD PMID:28801915 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454
JBrowse link
G Pnlip pancreatic lipase increases expression EXP manganese chloride results in increased expression of PNLIP mRNA CTD PMID:26745496 NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654
JBrowse link
G Pou1f1 POU class 1 homeobox 1 increases expression ISO manganese chloride results in increased expression of POU1F1 mRNA CTD PMID:17175027 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha affects expression
multiple interactions
increases acetylation
EXP
ISO
manganese chloride affects the expression of PPARGC1A protein
Hemin inhibits the reaction [manganese chloride affects the expression of PPARGC1A protein]
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in increased acetylation of PPARGC1A protein]]; [manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein]; manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]; Resveratrol inhibits the reaction [manganese chloride promotes the reaction [PPARGC1A protein binds to DNM1L promoter]]; Resveratrol inhibits the reaction [manganese chloride results in increased acetylation of PPARGC1A protein]
CTD PMID:30040983 PMID:34018660 PMID:34738708 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppp1r17 protein phosphatase 1, regulatory subunit 17 decreases expression EXP manganese chloride results in decreased expression of PPP1R17 mRNA CTD PMID:28801915 NCBI chr 4:85,213,595...85,230,607
Ensembl chr 4:85,213,887...85,230,603
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B decreases phosphorylation EXP manganese chloride results in decreased phosphorylation of PPP1R1B protein CTD PMID:23385959 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
JBrowse link
G Prim1 DNA primase subunit 1 decreases expression ISO manganese chloride results in decreased expression of PRIM1 mRNA CTD PMID:17175027 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
JBrowse link
G Prim2 DNA primase subunit 2 decreases expression ISO manganese chloride results in decreased expression of PRIM2 mRNA CTD PMID:17175027 NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP manganese chloride results in increased expression of PRIMA1 mRNA CTD PMID:28801915 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921
JBrowse link
G Primpol primase and DNA directed polymerase increases expression EXP manganese chloride results in increased expression of PRIMPOL mRNA CTD PMID:28801915 NCBI chr16:45,681,252...45,715,758
Ensembl chr16:45,681,326...45,715,565
JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 increases expression EXP manganese chloride results in increased expression of PRKAB2 mRNA CTD PMID:28801915 NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha decreases expression
multiple interactions
EXP manganese chloride results in decreased expression of PRKACA protein
[manganese chloride results in increased abundance of Manganese] which results in increased activity of PRKACA protein
CTD PMID:25981801 PMID:30951808 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression EXP manganese chloride results in increased expression of PRKAG2 mRNA CTD PMID:28801915 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
affects localization
increases activity
decreases expression
EXP 1,3-dimethylthiourea inhibits the reaction [manganese chloride affects the localization of PRKCA protein]; Reactive Oxygen Species affects the reaction [manganese chloride results in increased activity of PRKCA protein]
manganese chloride results in decreased expression of PRKCA protein
CTD PMID:17084486 PMID:25981801 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases activity
EXP
ISO
manganese chloride results in increased cleavage of and results in increased activity of PRKCD protein; rottlerin inhibits the reaction [manganese chloride results in increased activity of PRKCD protein]
SNCA protein inhibits the reaction [manganese chloride results in increased cleavage of and results in increased activity of PRKCD protein]
CTD PMID:21310168 PMID:25416158 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkcq protein kinase C, theta increases methylation
decreases expression
EXP manganese chloride results in increased methylation of PRKCQ gene
manganese chloride results in decreased expression of PRKCQ mRNA
CTD PMID:28801915 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Prkd1 protein kinase D1 increases expression ISO manganese chloride results in increased expression of PRKD1 mRNA CTD PMID:17175027 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase increases expression
decreases expression
increases methylation
EXP
ISO
manganese chloride results in increased expression of PRKN protein
manganese chloride results in decreased expression of PRKN mRNA
manganese chloride results in increased methylation of PRKN gene
CTD PMID:20635692 PMID:20798247 PMID:27913844 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Prl prolactin decreases expression EXP manganese chloride results in decreased expression of PRL protein CTD PMID:18603625 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prl7a3 prolactin family 7, subfamily A, member 3 increases expression EXP manganese chloride results in increased expression of PRL7A3 mRNA CTD PMID:26745496 NCBI chr17:37,086,164...37,099,039
Ensembl chr17:37,086,136...37,099,037
JBrowse link
G Prnd prion like protein doppel increases expression EXP manganese chloride results in increased expression of PRND mRNA CTD PMID:28801915 NCBI chr 3:119,213,462...119,218,742
Ensembl chr 3:119,213,429...119,218,745
JBrowse link
G Prnp prion protein multiple interactions
decreases response to substance
ISO PRNP protein inhibits the reaction [manganese chloride results in decreased abundance of Glutathione]; PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]; PRNP protein inhibits the reaction [manganese chloride results in increased chemical synthesis of Reactive Oxygen Species]
PRNP protein results in decreased susceptibility to manganese chloride
CTD PMID:17483122 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa increases expression EXP manganese chloride results in increased expression of PROC mRNA CTD PMID:28801915 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Prom2 prominin 2 increases expression EXP manganese chloride results in increased expression of PROM2 mRNA CTD PMID:28801915 NCBI chr 3:114,747,654...114,761,787
Ensembl chr 3:114,747,654...114,761,787
JBrowse link
G Pros1 protein S increases expression EXP manganese chloride results in increased expression of PROS1 mRNA CTD PMID:28801915 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286
JBrowse link
G Prrx1 paired related homeobox 1 increases expression EXP manganese chloride results in increased expression of PRRX1 mRNA CTD PMID:28801915 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866
JBrowse link
G Prss22 serine protease 22 increases expression EXP manganese chloride results in increased expression of PRSS22 mRNA CTD PMID:28801915 NCBI chr10:13,029,153...13,033,863
Ensembl chr10:13,029,153...13,033,863
JBrowse link
G Prss23 serine protease 23 decreases methylation
increases expression
EXP manganese chloride results in decreased methylation of PRSS23 gene
manganese chloride results in increased expression of PRSS23 mRNA
CTD PMID:28801915 NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091
JBrowse link
G Prxl2a peroxiredoxin like 2A increases methylation
decreases expression
EXP manganese chloride results in increased methylation of PRXL2A gene
manganese chloride results in decreased expression of PRXL2A mRNA
CTD PMID:28801915 NCBI chr16:16,866,601...16,886,378
Ensembl chr16:16,866,603...16,886,433
JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 decreases expression EXP manganese chloride results in decreased expression of PSD3 mRNA CTD PMID:28801915 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547
JBrowse link
G Ptdss2 phosphatidylserine synthase 2 increases expression EXP manganese chloride results in increased expression of PTDSS2 protein CTD PMID:23954760 NCBI chr 1:196,241,439...196,267,632
Ensembl chr 1:196,241,494...196,267,685
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression EXP manganese chloride results in increased expression of PTGR1 mRNA CTD PMID:22281203 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; bisindolylmaleimide I inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; rottlerin inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]
1,3-dimethylthiourea inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; [manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of PTGS2 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of PTGS2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; bisindolylmaleimide I inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; Reactive Oxygen Species affects the reaction [manganese chloride results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]
manganese chloride results in increased expression of PTGS2 mRNA; manganese chloride results in increased expression of PTGS2 protein
CTD PMID:17084486 PMID:17175027 PMID:19084589 PMID:21402727 PMID:28801915 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pthlh parathyroid hormone-like hormone increases expression EXP manganese chloride results in increased expression of PTHLH mRNA CTD PMID:28801915 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta decreases expression ISO manganese chloride results in decreased expression of PTK2B mRNA CTD PMID:17175027 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 increases expression EXP manganese chloride results in increased expression of PTPN5 mRNA CTD PMID:28801915 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression EXP manganese chloride results in decreased expression of PTPRD mRNA CTD PMID:28801915 NCBI chr 5:90,046,993...90,698,977
NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 increases expression EXP manganese chloride results in increased expression of PTPRZ1 mRNA CTD PMID:28801915 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218
JBrowse link
G Ptx3 pentraxin 3 increases expression ISO manganese chloride results in increased expression of PTX3 mRNA CTD PMID:17175027 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Pvalb parvalbumin decreases expression ISO manganese chloride results in decreased expression of PVALB mRNA; manganese chloride results in decreased expression of PVALB protein CTD PMID:25698507 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Pvr PVR cell adhesion molecule decreases expression ISO manganese chloride results in decreased expression of PVR mRNA CTD PMID:17175027 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression EXP manganese chloride results in increased expression of PYCR1 mRNA CTD PMID:28801915 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549
JBrowse link
G Pyy peptide YY increases expression EXP manganese chloride results in increased expression of PYY mRNA CTD PMID:28801915 NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
JBrowse link
G Qprt quinolinate phosphoribosyltransferase increases expression EXP manganese chloride results in increased expression of QPRT mRNA CTD PMID:28801915 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486
JBrowse link
G R3hcc1l R3H domain and coiled-coil containing 1-like increases expression EXP manganese chloride results in increased expression of R3HCC1L mRNA CTD PMID:28801915 NCBI chr 1:241,317,199...241,395,240
Ensembl chr 1:241,317,272...241,395,240
JBrowse link
G Rab20 RAB20, member RAS oncogene family increases expression EXP manganese chloride results in increased expression of RAB20 mRNA CTD PMID:28801915 NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529
JBrowse link
G Rab21 RAB21, member RAS oncogene family decreases expression ISO manganese chloride results in decreased expression of RAB21 mRNA CTD PMID:17175027 NCBI chr 7:50,904,050...50,928,890
Ensembl chr 7:50,904,057...50,928,839
JBrowse link
G Rab23 RAB23, member RAS oncogene family decreases expression ISO manganese chloride results in decreased expression of RAB23 mRNA CTD PMID:17175027 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Rab25 RAB25, member RAS oncogene family increases methylation EXP manganese chloride results in increased methylation of RAB25 gene CTD PMID:28801915 NCBI chr 2:174,000,323...174,006,422
Ensembl chr 2:174,000,323...174,006,422
JBrowse link
G Rab3a RAB3A, member RAS oncogene family multiple interactions
increases expression
EXP manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]; manganese chloride promotes the reaction [SNCA protein binds to [RAB3A protein binds to Guanosine Triphosphate]]; manganese chloride results in increased expression of [RAB3A protein binds to Guanosine Triphosphate]; SNCA protein promotes the reaction [manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]]
manganese chloride results in increased expression of RAB3A mRNA
CTD PMID:28801915 PMID:29289693 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336
JBrowse link
G Rabgap1 RAB GTPase activating protein 1 multiple interactions EXP manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]; SNCA protein promotes the reaction [manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]] CTD PMID:29289693 NCBI chr 3:21,208,012...21,326,013
Ensembl chr 3:21,208,055...21,326,013
JBrowse link
G Rasl11a RAS-like family 11 member A decreases expression EXP manganese chloride results in decreased expression of RASL11A mRNA CTD PMID:28801915 NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576
JBrowse link
G Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like increases expression EXP manganese chloride results in increased expression of RBPJL mRNA CTD PMID:28801915 NCBI chr 3:153,134,044...153,147,421
Ensembl chr 3:153,134,140...153,146,513
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
EXP
ISO
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [manganese chloride affects the localization of RELA protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of RELA protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of RELA protein]; LY 290042 inhibits the reaction [manganese chloride affects the localization of RELA protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]
[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein; Acetylcysteine affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein]; alpha-Tocopherol affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein]; IkK-16 compound affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein]
CTD PMID:15010209 PMID:22245093 PMID:33314588 PMID:34310962 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Reln reelin increases expression ISO manganese chloride results in increased expression of RELN mRNA CTD PMID:22407947 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Ret ret proto-oncogene decreases expression EXP manganese chloride results in decreased expression of RET protein CTD PMID:17555550 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176
JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO manganese chloride results in decreased expression of RFC5 mRNA CTD PMID:17175027 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G Rfk riboflavin kinase decreases expression EXP manganese chloride results in decreased expression of RFK mRNA CTD PMID:28801915 NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438
Ensembl chr  X:214,799,825...214,807,438
JBrowse link
G RGD1309362 similar to interferon-inducible GTPase increases expression EXP manganese chloride results in increased expression of RGD1309362 mRNA CTD PMID:28801915
G RGD1560203 similar to ferritin heavy polypeptide-like 17 increases expression EXP manganese chloride results in increased expression of RGD1560203 mRNA CTD PMID:28801915 NCBI chr  X:32,402,662...32,403,192
Ensembl chr  X:32,402,662...32,403,192
JBrowse link
G Rgs16 regulator of G-protein signaling 16 decreases expression EXP manganese chloride results in decreased expression of RGS16 mRNA CTD PMID:28801915 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO manganese chloride results in increased expression of RGS2 mRNA CTD PMID:17175027 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases methylation
increases expression
EXP manganese chloride results in increased methylation of RGS4 gene
manganese chloride results in increased expression of RGS4 mRNA
CTD PMID:28801915 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rgs5 regulator of G-protein signaling 5 decreases expression ISO manganese chloride results in decreased expression of RGS5 mRNA CTD PMID:17175027 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
JBrowse link
G Rgs6 regulator of G-protein signaling 6 increases expression ISO manganese chloride results in increased expression of RGS6 mRNA CTD PMID:17175027 NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753
JBrowse link
G Rhob ras homolog family member B increases expression ISO manganese chloride results in increased expression of RHOB mRNA CTD PMID:17467022 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rin2 Ras and Rab interactor 2 increases expression EXP manganese chloride results in increased expression of RIN2 mRNA CTD PMID:28801915 NCBI chr 3:133,086,858...133,303,604
Ensembl chr 3:133,086,749...133,303,604
JBrowse link
G Ripor3 RIPOR family member 3 increases expression EXP manganese chloride results in increased expression of FAM65C mRNA CTD PMID:28801915 NCBI chr 3:156,687,253...156,760,524
Ensembl chr 3:156,687,517...156,715,061
JBrowse link
G Rnf144b ring finger protein 144B increases expression EXP manganese chloride results in increased expression of RNF144B mRNA CTD PMID:28801915 NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760
JBrowse link
G Rnf145 ring finger protein 145 increases expression ISO manganese chloride results in increased expression of RNF145 mRNA CTD PMID:17175027 NCBI chr10:29,006,391...29,050,788
Ensembl chr10:29,011,548...29,050,781
JBrowse link
G Rnf157 ring finger protein 157 increases expression EXP manganese chloride results in increased expression of RNF157 mRNA CTD PMID:28801915 NCBI chr10:101,571,972...101,639,874
Ensembl chr10:101,566,295...101,639,942
JBrowse link
G Robo1 roundabout guidance receptor 1 increases expression EXP manganese chloride results in increased expression of ROBO1 mRNA CTD PMID:28801915 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203
JBrowse link
G Robo2 roundabout guidance receptor 2 increases expression EXP manganese chloride results in increased expression of ROBO2 mRNA CTD PMID:28801915 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536
JBrowse link
G Robo4 roundabout guidance receptor 4 increases expression ISO manganese chloride results in increased expression of ROBO4 mRNA CTD PMID:17467022 NCBI chr 8:37,119,953...37,133,887
Ensembl chr 8:37,119,988...37,132,519
JBrowse link
G Rpgr retinitis pigmentosa GTPase regulator increases expression EXP manganese chloride results in increased expression of RPGR mRNA CTD PMID:28801915 NCBI chr  X:12,566,447...12,628,171
Ensembl chr  X:12,566,645...12,747,882
JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) increases expression EXP manganese chloride results in increased expression of RPH3AL mRNA CTD PMID:28801915 NCBI chr10:60,689,943...60,833,354
Ensembl chr10:60,690,031...60,801,883
JBrowse link
G Rpp38 ribonuclease P/MRP subunit p38 increases expression EXP manganese chloride results in increased expression of RPP38 mRNA CTD PMID:28801915 NCBI chr17:74,914,066...74,917,742
Ensembl chr17:74,908,932...74,927,431
JBrowse link
G Rps23 ribosomal protein S23 decreases expression EXP manganese chloride results in decreased expression of RPS23 mRNA CTD PMID:28801915 NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation
decreases phosphorylation
multiple interactions
EXP
ISO
manganese chloride results in increased phosphorylation of RPS6KB1 protein
manganese chloride results in decreased phosphorylation of RPS6KB1 protein
corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of RPS6KB1 protein]
[[manganese chloride results in increased abundance of Manganese] which co-treated with Sirolimus] results in decreased phosphorylation of RPS6KB1 protein
CTD PMID:15342272 PMID:23604964 PMID:30578841 PMID:31690173 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G RragB Ras-related GTP binding B increases expression EXP manganese chloride results in increased expression of RRAGB mRNA CTD PMID:28801915 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression EXP manganese chloride results in increased expression of RSAD2 mRNA CTD PMID:28801915 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G Rtn4 reticulon 4 increases expression ISO manganese chloride results in increased expression of RTN4 mRNA CTD PMID:17467022 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP manganese chloride results in increased expression of RUNX2 mRNA CTD PMID:28801915 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G S100a10 S100 calcium binding protein A10 affects response to substance EXP S100A10 protein affects the susceptibility to manganese chloride CTD PMID:24067723 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
JBrowse link
G S100a16 S100 calcium binding protein A16 increases expression EXP manganese chloride results in increased expression of S100A16 mRNA CTD PMID:28801915 NCBI chr 2:176,016,405...176,022,117
Ensembl chr 2:176,016,268...176,022,117
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO manganese chloride results in increased expression of S100A6 mRNA CTD PMID:17175027 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G S100a9 S100 calcium binding protein A9 affects response to substance EXP S100A9 protein affects the susceptibility to manganese chloride CTD PMID:24067723 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G S100b S100 calcium binding protein B increases expression ISO manganese chloride results in increased expression of S100B mRNA; manganese chloride results in increased expression of S100B protein CTD PMID:15295902 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression ISO manganese chloride results in increased expression of S1PR1 mRNA CTD PMID:17467022 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Sall2 spalt-like transcription factor 2 increases expression EXP manganese chloride results in increased expression of SALL2 mRNA CTD PMID:28801915 NCBI chr15:25,021,345...25,038,918
Ensembl chr15:25,021,345...25,038,918
JBrowse link
G Samd5 sterile alpha motif domain containing 5 decreases expression EXP manganese chloride results in decreased expression of SAMD5 mRNA CTD PMID:28801915 NCBI chr 1:4,041,547...4,090,909
Ensembl chr 1:3,677,784...4,091,120
JBrowse link
G Samd9 sterile alpha motif domain containing 9 increases expression EXP manganese chloride results in increased expression of SAMD9 mRNA CTD PMID:28801915 NCBI chr 4:31,164,639...31,184,278
Ensembl chr 4:31,164,510...31,184,322
JBrowse link
G Samd9l sterile alpha motif domain containing 9 like increases expression EXP manganese chloride results in increased expression of SAMD9L mRNA CTD PMID:28801915 NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415
JBrowse link
G Sanbr SANT and BTB domain regulator of CSR increases expression EXP manganese chloride results in increased expression of SANBR mRNA CTD PMID:28801915 NCBI chr14:97,516,652...97,585,955
Ensembl chr14:97,516,413...97,581,346
JBrowse link
G Scara5 scavenger receptor class A, member 5 decreases expression EXP manganese chloride results in decreased expression of SCARA5 mRNA CTD PMID:28801915 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
increases methylation
EXP manganese chloride results in decreased expression of SCD mRNA
manganese chloride results in increased methylation of SCD gene
CTD PMID:28801915 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scd4 stearoyl-coenzyme A desaturase 4 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of SCD4 gene
manganese chloride results in decreased expression of SCD4 mRNA
CTD PMID:28801915 NCBI chr 1:243,203,433...243,216,007
Ensembl chr 1:243,203,881...243,215,148
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 increases expression ISO manganese chloride results in increased expression of SCN3B mRNA CTD PMID:17175027 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 increases expression EXP manganese chloride results in increased expression of SCN5A mRNA CTD PMID:28801915 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 decreases expression EXP manganese chloride results in decreased expression of SCN7A mRNA CTD PMID:26745496 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma decreases expression EXP manganese chloride results in decreased expression of SCNN1G mRNA CTD PMID:28801915 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
JBrowse link
G Sdcbp2 syndecan binding protein 2 decreases expression ISO manganese chloride results in decreased expression of SDCBP2 mRNA CTD PMID:17175027 NCBI chr 3:140,060,746...140,098,063
Ensembl chr 3:140,070,540...140,098,057
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A decreases expression EXP manganese chloride results in decreased expression of SDHA mRNA CTD PMID:22281203 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression EXP manganese chloride results in decreased expression of SELENBP1 mRNA CTD PMID:28801915 NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
JBrowse link
G Selp selectin P increases expression EXP manganese chloride results in increased expression of SELP mRNA CTD PMID:28801915 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Sema6a semaphorin 6A decreases expression EXP manganese chloride results in decreased expression of SEMA6A mRNA CTD PMID:28801915 NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954
JBrowse link
G Serpinb2 serpin family B member 2 increases expression EXP manganese chloride results in increased expression of SERPINB2 mRNA CTD PMID:26745496 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Serpine1 serpin family E member 1 decreases methylation
increases expression
EXP manganese chloride results in decreased methylation of SERPINE1 gene
manganese chloride results in increased expression of SERPINE1 mRNA
CTD PMID:28801915 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpine2 serpin family E member 2 increases expression EXP manganese chloride results in increased expression of SERPINE2 mRNA CTD PMID:28801915 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Serpini1 serpin family I member 1 decreases expression EXP manganese chloride results in decreased expression of SERPINI1 mRNA CTD PMID:28801915 NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135
JBrowse link
G Sesn2 sestrin 2 increases expression EXP manganese chloride results in increased expression of SESN2 mRNA CTD PMID:28801915 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sftpb surfactant protein B increases expression ISO manganese chloride results in increased expression of SFTPB mRNA CTD PMID:17175027 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sfxn3 sideroflexin 3 increases expression
decreases methylation
EXP manganese chloride results in increased expression of SFXN3 mRNA
manganese chloride results in decreased methylation of SFXN3 gene
CTD PMID:28801915 NCBI chr 1:243,907,958...243,917,065
Ensembl chr 1:243,907,751...243,917,073
JBrowse link
G Sfxn5 sideroflexin 5 increases expression ISO manganese chloride results in increased expression of SFXN5 mRNA CTD PMID:17175027 NCBI chr 4:117,750,213...117,869,826
Ensembl chr 4:117,752,806...117,869,794
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression EXP manganese chloride results in decreased expression of SGK1 mRNA; manganese chloride results in decreased expression of SGK1 protein CTD PMID:20737472 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sgms2 sphingomyelin synthase 2 increases expression EXP manganese chloride results in increased expression of SGMS2 mRNA CTD PMID:28801915 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546
JBrowse link
G Sh2d3c SH2 domain containing 3C multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of SH2D3C mRNA CTD PMID:35690225 NCBI chr 3:16,010,622...16,046,491
Ensembl chr 3:16,010,625...16,046,484
JBrowse link
G Sh3bgrl2 SH3 domain binding glutamate-rich protein like 2 increases expression EXP manganese chloride results in increased expression of SH3BGRL2 mRNA CTD PMID:28801915 NCBI chr 8:84,461,019...84,553,124
Ensembl chr 8:84,461,121...84,551,564
JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 decreases expression EXP manganese chloride results in decreased expression of SH3RF2 mRNA CTD PMID:28801915 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856
JBrowse link
G Shbg sex hormone binding globulin decreases expression EXP manganese chloride results in decreased expression of SHBG mRNA CTD PMID:28801915 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Shc3 SHC adaptor protein 3 decreases expression EXP manganese chloride results in decreased expression of SHC3 mRNA CTD PMID:28801915 NCBI chr17:13,652,247...13,772,710
Ensembl chr17:13,651,202...13,772,710
JBrowse link
G Shisa2 shisa family member 2 increases expression EXP manganese chloride results in increased expression of SHISA2 mRNA CTD PMID:28801915 NCBI chr15:33,806,715...33,811,013
Ensembl chr15:33,805,958...33,811,013
JBrowse link
G Shisa3 shisa family member 3 decreases expression EXP manganese chloride results in decreased expression of SHISA3 mRNA CTD PMID:28801915 NCBI chr14:40,563,672...40,568,244
Ensembl chr14:40,563,673...40,568,244
JBrowse link
G Shisa8 shisa family member 8 increases expression EXP manganese chloride results in increased expression of SHISA8 mRNA CTD PMID:28801915 NCBI chr 7:113,722,408...113,727,858
Ensembl chr 7:113,722,408...113,727,858
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 increases expression EXP manganese chloride results in increased expression of SIAH2 mRNA CTD PMID:28801915 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 increases expression EXP manganese chloride results in increased expression of SIGLEC10 mRNA CTD PMID:28801915 NCBI chr 1:93,817,301...93,826,376
Ensembl chr 1:93,817,335...93,825,931
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 increases expression EXP manganese chloride results in increased expression of SIGMAR1 protein CTD PMID:25732873 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
JBrowse link
G Sinhcaf SIN3-HDAC complex associated factor increases methylation
increases expression
EXP manganese chloride results in increased methylation of SINHCAF gene
manganese chloride results in increased expression of SINHCAF mRNA
CTD PMID:28801915 NCBI chr 4:181,888,301...181,913,294
Ensembl chr 4:181,888,312...181,910,276
JBrowse link
G Sipa1l2 signal-induced proliferation-associated 1 like 2 increases expression EXP manganese chloride results in increased expression of SIPA1L2 mRNA CTD PMID:28801915 NCBI chr19:53,389,792...53,540,466
Ensembl chr19:53,389,805...53,540,428
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression
ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in decreased expression of SIRT1 mRNA]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [manganese chloride results in decreased expression of SIRT1 protein]]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SIRT1 protein; Resveratrol inhibits the reaction [manganese chloride results in decreased expression of SIRT1 mRNA]; Resveratrol inhibits the reaction [manganese chloride results in decreased expression of SIRT1 protein]
manganese chloride results in decreased expression of SIRT1 mRNA; manganese chloride results in decreased expression of SIRT1 protein
CTD PMID:34018660 PMID:34738708 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt2 sirtuin 2 increases expression ISO manganese chloride results in increased expression of SIRT2 mRNA CTD PMID:17175027 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Six3 SIX homeobox 3 increases expression ISO manganese chloride results in increased expression of SIX3 mRNA CTD PMID:17175027 NCBI chr 6:9,039,017...9,043,336
Ensembl chr 6:9,036,434...9,053,301
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP manganese chloride results in decreased expression of SLC10A1 mRNA CTD PMID:28801915 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc11a1 solute carrier family 11 member 1 multiple interactions
increases expression
ISO [manganese chloride results in increased expression of SLC11A1 mRNA] which results in increased uptake of Copper; SLC11A1 protein affects the reaction [manganese chloride results in increased uptake of Copper] CTD PMID:22465424 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression
decreases uptake
multiple interactions
affects expression
increases transport
ISO
EXP
manganese chloride results in increased expression of SLC11A2 mRNA
SLC11A2 protein mutant form results in decreased uptake of manganese chloride
[[manganese chloride results in increased expression of SLC11A2 protein] which results in increased abundance of Manganese] which affects the abundance of Copper; [manganese chloride results in increased expression of SLC11A2 protein] which results in increased abundance of Manganese; Iron inhibits the reaction [SLC11A2 protein results in increased uptake of manganese chloride]
[manganese chloride results in increased abundance of Manganese] which results in increased expression of SLC11A2 mRNA; SLC11A2 protein affects the reaction [manganese chloride results in increased uptake of Copper]
manganese chloride affects the expression of SLC11A2 mRNA
manganese chloride results in increased expression of SLC11A2 mRNA; manganese chloride results in increased expression of SLC11A2 protein
SLC11A2 protein results in increased transport of manganese chloride
CTD PMID:17116743 PMID:17175027 PMID:20635692 PMID:22465424 PMID:22736759 More... NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc16a11 solute carrier family 16, member 11 increases expression EXP manganese chloride results in increased expression of SLC16A11 mRNA CTD PMID:28801915 NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915
JBrowse link
G Slc16a3 solute carrier family 16 member 3 increases expression ISO manganese chloride results in increased expression of SLC16A3 mRNA CTD PMID:17175027 NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
JBrowse link
G Slc16a6 solute carrier family 16, member 6 increases expression EXP manganese chloride results in increased expression of SLC16A6 mRNA CTD PMID:28801915 NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779
JBrowse link
G Slc18b1 solute carrier family 18 member B1 increases expression EXP manganese chloride results in increased expression of SLC18B1 mRNA CTD PMID:28801915 NCBI chr 1:21,628,235...21,670,807
Ensembl chr 1:21,628,237...21,670,684
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions
decreases expression
EXP
ISO
Raloxifene Hydrochloride inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 protein]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 mRNA]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 protein]
manganese chloride results in decreased expression of SLC1A2 mRNA; manganese chloride results in decreased expression of SLC1A2 protein
Estradiol inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 mRNA]; Estradiol inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 mRNA]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 protein]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 mRNA]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to SLC1A2 promoter]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 mRNA]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 mRNA]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to SLC1A2 promoter]]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein]; IkK-16 compound inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 mRNA]; IkK-16 compound inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to SLC1A2 promoter]]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 mRNA]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of SLC1A2 protein]
CTD PMID:19615351 PMID:24782323 PMID:29183790 PMID:29778792 PMID:34310962 More... NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a3 solute carrier family 1 member 3 multiple interactions
decreases expression
EXP
ISO
Raloxifene Hydrochloride inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 protein]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 mRNA]; Riluzole inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 protein]
manganese chloride results in decreased expression of SLC1A3 mRNA; manganese chloride results in decreased expression of SLC1A3 protein
Estradiol inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 mRNA]; Estradiol inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 mRNA]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 protein]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 mRNA]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of SLC1A3 protein]
CTD PMID:12387356 PMID:19615351 PMID:24782323 PMID:29183790 PMID:29778792 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases methylation
decreases expression
EXP manganese chloride results in increased methylation of SLC22A1 gene
manganese chloride results in decreased expression of SLC22A1 mRNA
CTD PMID:28801915 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a15 solute carrier family 22, member 15 decreases expression ISO manganese chloride results in decreased expression of SLC22A15 mRNA CTD PMID:17175027 NCBI chr 2:189,298,836...189,359,902
Ensembl chr 2:189,298,832...189,358,792
JBrowse link
G Slc24a3 solute carrier family 24 member 3 decreases expression EXP manganese chloride results in decreased expression of SLC24A3 mRNA CTD PMID:28801915 NCBI chr 3:132,552,119...133,051,192
Ensembl chr 3:132,551,595...133,051,192
JBrowse link
G Slc25a37 solute carrier family 25 member 37 increases expression EXP manganese chloride results in increased expression of SLC25A37 mRNA CTD PMID:28801915 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199
JBrowse link
G Slc26a4 solute carrier family 26 member 4 increases expression
decreases methylation
EXP manganese chloride results in increased expression of SLC26A4 mRNA
manganese chloride results in decreased methylation of SLC26A4 gene
CTD PMID:28801915 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression EXP manganese chloride results in increased expression of SLC29A1 mRNA CTD PMID:28801915 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc2a12 solute carrier family 2 member 12 decreases expression EXP manganese chloride results in decreased expression of SLC2A12 mRNA CTD PMID:28801915 NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971
JBrowse link
G Slc2a13 solute carrier family 2 member 13 increases expression ISO manganese chloride results in increased expression of SLC2A13 mRNA CTD PMID:17175027 NCBI chr 7:122,399,329...122,726,605
Ensembl chr 7:122,399,330...122,726,605
JBrowse link
G Slc30a10 solute carrier family 30, member 10 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of SLC30A10 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of SLC30A10 protein CTD PMID:34590183 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103
JBrowse link
G Slc31a1 solute carrier family 31 member 1 decreases expression EXP manganese chloride results in decreased expression of SLC31A1 mRNA CTD PMID:28801915 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
JBrowse link
G Slc38a10 solute carrier family 38, member 10 increases expression ISO manganese chloride results in increased expression of SLC38A10 mRNA CTD PMID:17175027 NCBI chr10:105,386,836...105,436,636
Ensembl chr10:105,386,836...105,436,636
JBrowse link
G Slc38a3 solute carrier family 38, member 3 multiple interactions
decreases expression
increases degradation
EXP acetylleucyl-leucyl-norleucinal inhibits the reaction [manganese chloride results in increased degradation of SLC38A3 protein]; lactacystin inhibits the reaction [manganese chloride results in increased degradation of SLC38A3 protein]
manganese chloride results in decreased expression of SLC38A3 protein
CTD PMID:20737472 NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
JBrowse link
G Slc38a4 solute carrier family 38, member 4 decreases expression EXP manganese chloride results in decreased expression of SLC38A4 mRNA CTD PMID:28801915 NCBI chr 7:128,142,866...128,203,000
Ensembl chr 7:128,144,807...128,202,995
JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression ISO manganese chloride results in increased expression of SLC39A14 mRNA CTD PMID:17065364 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
JBrowse link
G Slc39a8 solute carrier family 39 member 8 increases uptake
multiple interactions
EXP SLC39A8 protein results in increased uptake of manganese chloride
SLC39A8 protein affects the reaction [Sodium Bicarbonate results in increased uptake of manganese chloride]
CTD PMID:21509381 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Slc40a1 solute carrier family 40 member 1 decreases expression EXP manganese chloride results in decreased expression of SLC40A1 mRNA CTD PMID:28801915 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
JBrowse link
G Slc49a3 solute carrier family 49 member 3 increases expression EXP manganese chloride results in increased expression of SLC49A3 mRNA CTD PMID:28801915 NCBI chr14:1,305,091...1,319,723
Ensembl chr14:1,305,680...1,314,132
JBrowse link
G Slc4a10 solute carrier family 4 member 10 decreases expression ISO manganese chloride results in decreased expression of SLC4A10 mRNA CTD PMID:17175027 NCBI chr 3:46,665,076...46,959,088
Ensembl chr 3:46,665,265...46,957,268
JBrowse link
G Slc51b SLC51 subunit beta decreases expression EXP manganese chloride results in decreased expression of SLC51B mRNA CTD PMID:28801915 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145
JBrowse link
G Slc5a7 solute carrier family 5 member 7 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC5A7 mRNA CTD PMID:30738988 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258
JBrowse link
G Slc6a1 solute carrier family 6 member 1 multiple interactions
decreases expression
increases expression
EXP [Iron deficiency co-treated with manganese chloride] results in decreased expression of SLC6A1 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of SLC6A1 protein; [Iron deficiency co-treated with manganese chloride] results in increased expression of SLC6A1 mRNA
manganese chloride results in decreased expression of SLC6A1 mRNA; manganese chloride results in decreased expression of SLC6A1 protein
manganese chloride results in increased expression of SLC6A1 mRNA
CTD PMID:18771689 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
decreases expression
ISO
EXP
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC6A3 protein]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of SLC6A3 protein]
manganese chloride results in decreased expression of SLC6A3; manganese chloride results in decreased expression of SLC6A3 protein
[manganese chloride co-treated with Iron deficiency] results in decreased expression of SLC6A3 protein
CTD PMID:16571372 PMID:22479410 PMID:23458069 PMID:24969583 PMID:27193731 More... NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc7a1 solute carrier family 7 member 1 increases expression EXP manganese chloride results in increased expression of SLC7A1 mRNA CTD PMID:28801915 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression EXP manganese chloride results in increased expression of SLC7A11 mRNA CTD PMID:28801915 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc7a3 solute carrier family 7 member 3 increases expression EXP manganese chloride results in increased expression of SLC7A3 mRNA CTD PMID:28801915 NCBI chr  X:66,210,071...66,216,482
Ensembl chr  X:66,210,081...66,215,708
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP manganese chloride results in decreased expression of SLCO1A4 mRNA CTD PMID:26745496 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco3a1 solute carrier organic anion transporter family, member 3a1 increases expression EXP manganese chloride results in increased expression of SLCO3A1 mRNA CTD PMID:28801915 NCBI chr 1:128,106,232...128,388,043
Ensembl chr 1:128,106,228...128,387,925
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression EXP manganese chloride results in increased expression of SLCO4A1 mRNA CTD PMID:28801915 NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
JBrowse link
G Smad7 SMAD family member 7 increases methylation ISO manganese chloride results in increased methylation of SMAD7 gene CTD PMID:27913844 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smim14 small integral membrane protein 14 increases expression ISO manganese chloride results in increased expression of SMIM14 mRNA CTD PMID:17175027 NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760
JBrowse link
G Snca synuclein alpha increases expression
affects folding
multiple interactions
EXP
ISO
manganese chloride results in increased expression of SNCA; manganese chloride results in increased expression of SNCA mRNA; manganese chloride results in increased expression of SNCA protein
manganese chloride affects the folding of SNCA protein
Glutathione inhibits the reaction [manganese chloride promotes the reaction [SNCA protein binds to SNCA protein binds to SNCA protein]]; Hydrogen Peroxide promotes the reaction [manganese chloride promotes the reaction [SNCA protein binds to SNCA protein binds to SNCA protein]]; manganese chloride promotes the reaction [SNCA protein binds to [RAB3A protein binds to Guanosine Triphosphate]]; manganese chloride promotes the reaction [SNCA protein binds to SNCA protein binds to SNCA protein]; SNCA protein promotes the reaction [manganese chloride inhibits the reaction [[RAB3A protein binds to Guanosine Triphosphate] which binds to RABGAP1 protein]]; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2A protein]; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased phosphorylation of EIF2AK3 protein]; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased splicing of XBP1 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of ATF4 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein]; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of DDIT3 protein]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSP90B1 protein]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of HSPA5 protein]; SNCA protein promotes the reaction [manganese chloride results in increased phosphorylation of ERN1 protein]
[manganese chloride co-treated with SNCA protein] results in increased expression of IL1B mRNA; [manganese chloride co-treated with SNCA protein] results in increased expression of IL1B protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of SNCA protein; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]]; manganese chloride promotes the reaction [HMGB1 protein binds to SNCA protein]; manganese chloride promotes the reaction [SNCA protein binds to SNCA protein]; manganese chloride promotes the reaction [SNCA protein results in increased expression of [IL12A protein binds to IL12B protein]]; manganese chloride promotes the reaction [SNCA protein results in increased expression of CSF2 mRNA]; manganese chloride promotes the reaction [SNCA protein results in increased expression of IL6 mRNA]; manganese chloride promotes the reaction [SNCA protein results in increased expression of TNF protein]; SNCA gene inhibits the reaction [DJR-1.1 mutant form promotes the reaction [manganese chloride results in increased abundance of Reactive Nitrogen Species]]; SNCA gene inhibits the reaction [DJR-1.1 mutant form promotes the reaction [manganese chloride results in increased abundance of Reactive Oxygen Species]]; SNCA gene inhibits the reaction [PDR-1 mutant form promotes the reaction [manganese chloride results in increased abundance of Reactive Nitrogen Species]]; SNCA gene inhibits the reaction [PDR-1 mutant form promotes the reaction [manganese chloride results in increased abundance of Reactive Oxygen Species]]; SNCA gene inhibits the reaction [PDR-1 mutant form results in increased susceptibility to manganese chloride]; SNCA protein inhibits the reaction [manganese chloride affects the localization of CYCS protein]; SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]; SNCA protein inhibits the reaction [manganese chloride results in increased cleavage of and results in increased activity of PRKCD protein]
CTD PMID:11553618 PMID:19276553 PMID:23353026 PMID:23934647 PMID:24452053 More... NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Snx20 sorting nexin 20 increases expression EXP manganese chloride results in increased expression of SNX20 mRNA CTD PMID:28801915 NCBI chr19:18,435,935...18,445,108
Ensembl chr19:18,435,935...18,445,107
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP manganese chloride results in increased expression of SOCS1 mRNA CTD PMID:28801915 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases activity
ISO
EXP
HFE gene mutant form inhibits the reaction [manganese chloride results in decreased activity of SOD1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SOD1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SOD1 protein
CTD PMID:25874029 PMID:38129942 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
increases expression
multiple interactions
increases activity
EXP
ISO
manganese chloride results in decreased expression of SOD2 protein
manganese chloride results in increased expression of SOD2 protein
manganese chloride results in increased expression of SOD2 mRNA; manganese chloride results in increased expression of SOD2 protein
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [manganese chloride results in increased expression of SOD2 mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [manganese chloride results in increased expression of SOD2 protein]; Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 mRNA]; Deoxyglucose inhibits the reaction [manganese chloride results in increased expression of SOD2 protein]; manganese chloride inhibits the reaction [Glucose results in decreased activity of SOD2 protein]; Pyruvates inhibits the reaction [manganese chloride results in increased expression of SOD2 mRNA]; Pyruvates inhibits the reaction [manganese chloride results in increased expression of SOD2 protein]
[Plant Extracts co-treated with manganese chloride] results in increased expression of SOD2 protein; Melatonin affects the reaction [manganese chloride results in decreased expression of SOD2 protein]
manganese chloride results in increased activity of SOD2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SOD2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of SOD2 protein
CTD PMID:10328827 PMID:15922012 PMID:17175027 PMID:22154916 PMID:23329836 More... NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sorcs2 sortilin-related VPS10 domain containing receptor 2 increases expression EXP manganese chloride results in increased expression of SORCS2 mRNA CTD PMID:28801915 NCBI chr14:74,371,089...74,735,943
Ensembl chr14:74,371,415...74,735,943
JBrowse link
G Sort1 sortilin 1 decreases expression ISO manganese chloride results in decreased expression of SORT1 mRNA CTD PMID:17175027 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Sostdc1 sclerostin domain containing 1 decreases expression
increases methylation
EXP manganese chloride results in decreased expression of SOSTDC1 mRNA
manganese chloride results in increased methylation of SOSTDC1 gene
CTD PMID:26745496 PMID:28801915 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579
JBrowse link
G Sox8 SRY-box transcription factor 8 increases expression EXP manganese chloride results in increased expression of SOX8 mRNA CTD PMID:28801915 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Spa17 sperm autoantigenic protein 17 decreases expression ISO manganese chloride results in decreased expression of SPA17 mRNA CTD PMID:17175027 NCBI chr 8:37,307,432...37,318,519
Ensembl chr 8:37,307,557...37,318,639
JBrowse link
G Spata1 spermatogenesis associated 1 increases expression EXP manganese chloride results in increased expression of SPATA1 mRNA CTD PMID:28801915 NCBI chr 2:235,349,126...235,394,578
Ensembl chr 2:235,349,127...235,394,502
JBrowse link
G Spats1 spermatogenesis associated, serine-rich 1 increases expression EXP manganese chloride results in increased expression of SPATS1 mRNA CTD PMID:28801915 NCBI chr 9:15,527,179...15,562,286
Ensembl chr 9:15,527,142...15,562,280
JBrowse link
G Spib Spi-B transcription factor increases expression EXP manganese chloride results in increased expression of SPIB mRNA CTD PMID:28801915 NCBI chr 1:95,018,939...95,024,804
Ensembl chr 1:95,018,947...95,024,780
JBrowse link
G Spon1 spondin 1 increases expression EXP manganese chloride results in increased expression of SPON1 mRNA CTD PMID:28801915 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
JBrowse link
G Spry4 sprouty RTK signaling antagonist 4 increases expression EXP manganese chloride results in increased expression of SPRY4 mRNA CTD PMID:28801915 NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004
JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 decreases expression EXP manganese chloride results in decreased expression of SPTBN2 mRNA CTD PMID:28801915 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression
affects expression
ISO
EXP
[N-((3-(aminomethyl)phenyl)methyl)ethanimidamide co-treated with manganese chloride] results in decreased expression of SQSTM1 protein; corynoxine B affects the reaction [manganese chloride affects the expression of SQSTM1 protein]
Acetylcysteine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein]; Chloroquine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein]; Resveratrol promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein]; Sirolimus inhibits the reaction [manganese chloride results in increased expression of SQSTM1 protein]
[manganese chloride results in increased abundance of Manganese] which results in increased expression of SQSTM1 protein; Sirolimus inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of SQSTM1 protein]; SQSTM1 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of SQSTM1 protein]
CTD PMID:28856835 PMID:29222055 PMID:30578841 PMID:30672645 PMID:31690173 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [AG 1879 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]]; [CGP 77675 results in decreased activity of SRC protein] promotes the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srpx2 sushi-repeat-containing protein, X-linked 2 increases expression EXP manganese chloride results in increased expression of SRPX2 mRNA CTD PMID:28801915 NCBI chr  X:97,106,455...97,132,197
Ensembl chr  X:97,106,561...97,132,195
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression EXP manganese chloride results in increased expression of ST6GAL1 mRNA CTD PMID:28801915 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
EXP
ISO
[manganese chloride results in decreased expression of STAR protein] which results in decreased chemical synthesis of Steroids
manganese chloride inhibits the reaction [CGB3 protein results in increased expression of STAR protein]
CTD PMID:12699903 PMID:25981801 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
increases methylation
multiple interactions
EXP
ISO
manganese chloride results in decreased expression of STAT3 mRNA
manganese chloride results in increased methylation of STAT3 gene
[manganese chloride results in increased abundance of Manganese] affects the reaction [STAT3 protein binds to PPARGC1A protein]; [manganese chloride results in increased abundance of Manganese] which affects the localization of STAT3 protein
CTD PMID:28801915 PMID:34018660 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Steap1 STEAP family member 1 decreases expression EXP manganese chloride results in decreased expression of STEAP1 mRNA CTD PMID:28801915 NCBI chr 4:28,276,972...28,287,484
Ensembl chr 4:28,276,909...28,287,479
JBrowse link
G Stox1 storkhead box 1 decreases expression ISO manganese chloride results in decreased expression of STOX1 mRNA CTD PMID:17175027 NCBI chr20:30,598,284...30,666,371
Ensembl chr20:30,598,168...30,666,939
JBrowse link
G Strn striatin increases expression ISO manganese chloride results in increased expression of STRN mRNA CTD PMID:15295902 NCBI chr 6:16,335,265...16,422,159
Ensembl chr 6:16,335,358...16,417,083
JBrowse link
G Stx16 syntaxin 16 increases expression EXP manganese chloride results in increased expression of STX16 mRNA CTD PMID:28801915 NCBI chr 3:162,853,764...162,882,489
Ensembl chr 3:162,853,782...162,882,489
JBrowse link
G Sulf1 sulfatase 1 decreases expression EXP manganese chloride results in decreased expression of SULF1 mRNA CTD PMID:28801915 NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 increases expression ISO manganese chloride results in increased expression of SULT1C1 mRNA CTD PMID:17175027 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Sycp1 synaptonemal complex protein 1 increases expression ISO manganese chloride results in increased expression of SYCP1 mRNA CTD PMID:15295902 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737
JBrowse link
G Syndig1l synapse differentiation inducing 1-like decreases expression EXP manganese chloride results in decreased expression of SYNDIG1L mRNA CTD PMID:28801915 NCBI chr 6:104,318,096...104,344,989
Ensembl chr 6:104,323,424...104,344,891
JBrowse link
G Syne4 spectrin repeat containing nuclear envelope family member 4 decreases expression EXP manganese chloride results in decreased expression of SYNE4 mRNA CTD PMID:28801915 NCBI chr 1:85,569,409...85,573,775
Ensembl chr 1:85,569,545...85,573,760
JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 increases expression EXP manganese chloride results in increased expression of SYNGAP1 mRNA CTD PMID:28801915 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672
JBrowse link
G Synpo2l synaptopodin 2-like increases expression EXP manganese chloride results in increased expression of SYNPO2L mRNA CTD PMID:28801915 NCBI chr15:3,631,974...3,641,429
Ensembl chr15:3,631,834...3,641,429
JBrowse link
G Sytl4 synaptotagmin-like 4 increases expression EXP manganese chloride results in increased expression of SYTL4 mRNA CTD PMID:28801915 NCBI chr  X:97,135,496...97,185,867
Ensembl chr  X:97,135,500...97,185,854
JBrowse link
G Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 increases expression EXP manganese chloride results in increased expression of TAB3 mRNA CTD PMID:28801915 NCBI chr  X:49,972,414...50,044,658
Ensembl chr  X:49,972,330...50,042,056
JBrowse link
G Tacr1 tachykinin receptor 1 decreases expression ISO manganese chloride results in decreased expression of TACR1 mRNA CTD PMID:17175027 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tacr2 tachykinin receptor 2 increases expression EXP manganese chloride results in increased expression of TACR2 mRNA CTD PMID:28801915 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446
JBrowse link
G Taf4b TATA-box binding protein associated factor 4b increases expression EXP manganese chloride results in increased expression of TAF4B mRNA CTD PMID:28801915 NCBI chr18:5,952,737...6,086,408
Ensembl chr18:5,952,769...6,068,307
JBrowse link
G Taf7l TATA-box binding protein associated factor 7-like increases expression EXP manganese chloride results in increased expression of TAF7L mRNA CTD PMID:28801915 NCBI chr  X:97,660,222...97,675,241
Ensembl chr  X:97,660,222...97,675,023
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b decreases expression EXP manganese chloride results in decreased expression of TAF9B mRNA CTD PMID:28801915 NCBI chr  X:71,289,290...71,300,142
Ensembl chr  X:71,289,290...71,300,604
JBrowse link
G Tagln2 transgelin 2 decreases expression ISO manganese chloride results in decreased expression of TAGLN2 mRNA CTD PMID:17175027 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
JBrowse link
G Tamalin trafficking regulator and scaffold protein tamalin increases expression EXP manganese chloride results in increased expression of TAMALIN mRNA CTD PMID:28801915 NCBI chr 7:132,338,900...132,359,519
Ensembl chr 7:132,338,900...132,346,666
JBrowse link
G Tbx1 T-box transcription factor 1 decreases expression ISO manganese chloride results in decreased expression of TBX1 mRNA CTD PMID:17467022 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Tbx18 T-box transcription factor 18 increases expression ISO manganese chloride results in increased expression of TBX18 mRNA CTD PMID:17175027 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058
JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression EXP manganese chloride results in increased expression of TBXAS1 mRNA CTD PMID:28801915 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
G Tcim transcriptional and immune response regulator increases expression ISO manganese chloride results in increased expression of TCIM mRNA CTD PMID:17175027 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581
JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 decreases expression EXP manganese chloride results in decreased expression of TECPR1 mRNA CTD PMID:28801915 NCBI chr12:10,391,587...10,420,462
Ensembl chr12:10,391,696...10,419,611
JBrowse link
G Tek TEK receptor tyrosine kinase increases expression ISO manganese chloride results in increased expression of TEK mRNA CTD PMID:17467022 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tenm3 teneurin transmembrane protein 3 increases expression EXP manganese chloride results in increased expression of TENM3 mRNA CTD PMID:28801915 NCBI chr16:41,251,909...43,978,594
Ensembl chr16:41,252,182...43,978,594
JBrowse link
G Tex101 testis expressed 101 decreases expression EXP manganese chloride results in decreased expression of TEX101 mRNA CTD PMID:28801915 NCBI chr 1:80,255,076...80,259,442
Ensembl chr 1:80,255,076...80,259,442
JBrowse link
G Tex26 testis expressed 26 decreases expression EXP manganese chloride results in decreased expression of TEX26 mRNA CTD PMID:28801915 NCBI chr12:5,573,691...5,605,209
Ensembl chr12:5,573,691...5,610,498
JBrowse link
G Tfap2b transcription factor AP-2 beta increases expression ISO manganese chloride results in increased expression of TFAP2B mRNA CTD PMID:17175027 NCBI chr 9:21,786,251...21,816,054
Ensembl chr 9:21,786,258...21,814,520
JBrowse link
G Tfeb transcription factor EB multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which affects the localization of TFEB protein; [manganese chloride results in increased abundance of Manganese] which results in decreased activity of TFEB protein; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of TFEB protein] CTD PMID:31690173 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
JBrowse link
G Tff2 trefoil factor 2 increases expression EXP manganese chloride results in increased expression of TFF2 mRNA CTD PMID:28801915 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619
JBrowse link
G Tfrc transferrin receptor increases expression EXP manganese chloride results in increased expression of TFRC mRNA; manganese chloride results in increased expression of TFRC protein CTD PMID:15893546 PMID:15922012 PMID:16545456 PMID:16568477 PMID:28801915 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgfa transforming growth factor alpha decreases expression
multiple interactions
ISO manganese chloride results in decreased expression of TGFA protein
Estradiol inhibits the reaction [manganese chloride results in decreased expression of TGFA protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of TGFA protein]
CTD PMID:29183790 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
EXP
ISO
manganese chloride results in increased expression of TGFB1 mRNA
[manganese chloride results in increased abundance of Manganese] which affects the expression of TGFB1 mRNA; [manganese chloride results in increased abundance of Manganese] which affects the expression of TGFB1 protein
CTD PMID:28801915 PMID:34018660 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP manganese chloride results in increased expression of TGFB2 mRNA CTD PMID:28801915 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression EXP manganese chloride results in decreased expression of TGFB3 mRNA CTD PMID:28801915 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression ISO manganese chloride results in decreased expression of TGFBR1 mRNA CTD PMID:17175027 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases activity
increases expression
decreases expression
increases methylation
EXP
ISO
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein; [Wortmannin co-treated with manganese chloride] results in decreased expression of TH protein; manganese chloride results in increased activity of and results in increased phosphorylation of TH protein; rottlerin inhibits the reaction [manganese chloride results in decreased activity of TH protein]
manganese chloride results in increased expression of TH mRNA; manganese chloride results in increased expression of TH protein
manganese chloride results in decreased expression of TH protein
manganese chloride results in decreased expression of TH mRNA; manganese chloride results in decreased expression of TH protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of TH mRNA]; Estradiol inhibits the reaction [manganese chloride results in decreased expression of TH protein]; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of TH protein]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of TH protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of TH mRNA]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of TH protein]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of TH mRNA]; Valproic Acid inhibits the reaction [manganese chloride results in decreased expression of TH protein]
manganese chloride results in increased methylation of TH gene
CTD PMID:12106697 PMID:20798247 PMID:21310168 PMID:23604964 PMID:24969583 More... NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO manganese chloride results in increased expression of THBS1 mRNA CTD PMID:17467022 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 increases expression ISO manganese chloride results in increased expression of TIE1 mRNA CTD PMID:17467022 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592
JBrowse link
G Tle2 TLE family member 2, transcriptional corepressor decreases expression EXP manganese chloride results in decreased expression of TLE2 mRNA CTD PMID:28801915 NCBI chr 7:8,119,049...8,135,385
Ensembl chr 7:8,119,053...8,134,306
JBrowse link
G Tln1 talin 1 multiple interactions
decreases response to substance
ISO manganese chloride inhibits the reaction [TLN1 protein mutant form results in decreased activity of [ITGB3 protein binds to ITGA2B protein]]
manganese chloride results in decreased susceptibility to TLN1 protein mutant form
CTD PMID:20971947 NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900
JBrowse link
G Tlr5 toll-like receptor 5 decreases expression EXP manganese chloride results in decreased expression of TLR5 mRNA CTD PMID:28801915 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738
JBrowse link
G Tlr6 toll-like receptor 6 decreases expression EXP manganese chloride results in decreased expression of TLR6 mRNA CTD PMID:28801915 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685
JBrowse link
G Tmbim7 transmembrane BAX inhibitor motif containing 7 decreases methylation EXP manganese chloride results in decreased methylation of TMBIM7 gene CTD PMID:28801915 NCBI chr 4:30,466,651...30,499,565
Ensembl chr 4:30,466,653...30,499,256
JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 decreases expression EXP manganese chloride results in decreased expression of TMCC3 mRNA CTD PMID:28801915 NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926
JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 increases expression EXP manganese chloride results in increased expression of TMEFF1 mRNA CTD PMID:28801915 NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493
JBrowse link
G Tmem140 transmembrane protein 140 decreases expression EXP manganese chloride results in decreased expression of TMEM140 mRNA CTD PMID:28801915 NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455
JBrowse link
G Tmem178a transmembrane protein 178A decreases expression EXP manganese chloride results in decreased expression of TMEM178A mRNA CTD PMID:28801915 NCBI chr 6:14,004,629...14,063,677
Ensembl chr 6:14,004,630...14,063,549
JBrowse link
G Tmem220 transmembrane protein 220 increases expression EXP manganese chloride results in increased expression of TMEM220 mRNA CTD PMID:28801915 NCBI chr10:51,719,777...51,728,792
Ensembl chr10:51,719,777...51,728,776
JBrowse link
G Tmem25 transmembrane protein 25 increases expression EXP manganese chloride results in increased expression of TMEM25 mRNA CTD PMID:28801915 NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389
JBrowse link
G Tmem255b transmembrane protein 255B increases expression EXP manganese chloride results in increased expression of TMEM255B mRNA CTD PMID:26745496 NCBI chr16:76,079,840...76,108,179
Ensembl chr16:76,079,845...76,106,795
JBrowse link
G Tmem59l transmembrane protein 59-like increases expression EXP manganese chloride results in increased expression of TMEM59L mRNA CTD PMID:28801915 NCBI chr16:18,941,370...18,945,381
Ensembl chr16:18,941,567...18,945,381
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
EXP
ISO
[manganese chloride results in increased abundance of Manganese] which results in increased expression of TNF protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of TNF protein]; Minocycline inhibits the reaction [manganese chloride results in increased expression of TNF protein]; Quercetin inhibits the reaction [manganese chloride results in increased expression of TNF protein]; Raloxifene Hydrochloride inhibits the reaction [manganese chloride results in increased secretion of TNF protein]
[manganese chloride results in increased abundance of Manganese] which results in increased expression of TNF mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of TNF protein; [Plant Extracts co-treated with manganese chloride] affects the expression of TNF protein; Acetylcysteine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Buthionine Sulfoximine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Lipopolysaccharides promotes the reaction [manganese chloride results in increased expression of TNF protein]; manganese chloride promotes the reaction [[TNF protein co-treated with IFNG protein] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]; manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased chemical synthesis of IFNG protein co-treated with and results in increased chemical synthesis of Nitric Oxide]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 mRNA]]; NFKBIA protein affects the reaction [manganese chloride promotes the reaction [TNF protein co-treated with and results in increased expression of IFNG protein co-treated with and results in increased expression of NOS2 protein]]; Pentoxifylline inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; tin protoporphyrin IX inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]]; tin protoporphyrin IX inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]]
manganese chloride results in increased expression of TNF mRNA; manganese chloride results in increased expression of TNF protein
[manganese chloride results in increased abundance of Manganese] which results in increased secretion of TNF protein; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased secretion of TNF protein]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased secretion of TNF protein]; manganese chloride promotes the reaction [SNCA protein results in increased expression of TNF protein]
CTD PMID:15601679 PMID:16168523 PMID:18836210 PMID:20798247 PMID:21963524 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression EXP manganese chloride results in increased expression of TNFAIP2 mRNA CTD PMID:28801915 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO manganese chloride promotes the reaction [ITIH1 protein binds to TNFAIP6 protein]; manganese chloride promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression ISO manganese chloride results in increased expression of TNFRSF12A mRNA CTD PMID:17467022 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnfrsf13b TNF receptor superfamily member 13B increases expression EXP manganese chloride results in increased expression of TNFRSF13B mRNA CTD PMID:28801915 NCBI chr10:45,801,860...45,824,932
Ensembl chr10:45,801,860...45,822,987
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO manganese chloride results in increased expression of TNFRSF25 mRNA CTD PMID:17175027 NCBI chr 5:162,621,669...162,626,341
Ensembl chr 5:162,622,075...162,626,341
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression EXP manganese chloride results in increased expression of TNFRSF9 mRNA CTD PMID:28801915 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf15 TNF superfamily member 15 increases expression EXP manganese chloride results in increased expression of TNFSF15 mRNA CTD PMID:28801915 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228
JBrowse link
G Tnn tenascin N increases methylation
decreases expression
EXP manganese chloride results in increased methylation of TNN gene
manganese chloride results in decreased expression of TNN mRNA
CTD PMID:28801915 NCBI chr13:72,319,160...72,386,362
Ensembl chr13:72,319,155...72,408,156
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type decreases expression EXP manganese chloride results in decreased expression of TNNC1 mRNA CTD PMID:28801915 NCBI chr16:6,400,801...6,405,634
Ensembl chr16:6,402,171...6,405,634
JBrowse link
G Tnnt1 troponin T1, slow skeletal type increases expression EXP manganese chloride results in increased expression of TNNT1 mRNA CTD PMID:28801915 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Tnrc18 trinucleotide repeat containing 18 decreases expression EXP manganese chloride results in decreased expression of TNRC18 mRNA CTD PMID:28801915 NCBI chr12:11,755,394...11,851,717
Ensembl chr12:11,755,392...11,851,384
JBrowse link
G Tnrc6a trinucleotide repeat containing adaptor 6A increases expression ISO manganese chloride results in increased expression of TNRC6A mRNA CTD PMID:17175027 NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
JBrowse link
G Tns4 tensin 4 increases expression EXP manganese chloride results in increased expression of TNS4 mRNA CTD PMID:28801915 NCBI chr10:84,021,965...84,041,346
Ensembl chr10:84,021,966...84,041,346
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
EXP manganese chloride results in increased expression of TP53 mRNA
[manganese chloride results in increased abundance of Manganese] which results in increased expression of TP53 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of TP53 protein]
CTD PMID:17623882 PMID:30844427 PMID:33314588 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp73 tumor protein p73 decreases expression
decreases response to substance
EXP
ISO
manganese chloride results in decreased expression of TP73 mRNA; manganese chloride results in decreased expression of TP73 protein modified form
TP73 protein modified form results in decreased susceptibility to manganese chloride
manganese chloride results in decreased expression of TRP73 protein modified form
CTD PMID:27107493 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Tpcn1 two pore segment channel 1 increases expression ISO
EXP
manganese chloride results in increased expression of TPCN1 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr12:35,972,813...36,029,632
Ensembl chr12:35,972,846...36,029,626
JBrowse link
G Tprg1 tumor protein p63 regulated 1 increases expression EXP manganese chloride results in increased expression of TPRG1 mRNA CTD PMID:28801915 NCBI chr11:75,322,470...75,449,907
Ensembl chr11:75,322,470...75,449,907
JBrowse link
G Tprn taperin decreases expression EXP manganese chloride results in decreased expression of TPRN mRNA CTD PMID:28801915 NCBI chr 3:8,076,164...8,083,642
Ensembl chr 3:8,075,137...8,083,642
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP manganese chloride results in increased expression of TRIB3 mRNA CTD PMID:28801915 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim14 tripartite motif-containing 14 increases expression EXP manganese chloride results in increased expression of TRIM14 mRNA CTD PMID:28801915 NCBI chr 5:60,800,568...60,824,858
Ensembl chr 5:60,800,032...60,824,858
JBrowse link
G Trim35 tripartite motif-containing 35 decreases expression EXP manganese chloride results in decreased expression of TRIM35 mRNA CTD PMID:28801915 NCBI chr15:40,493,697...40,510,246
Ensembl chr15:40,493,755...40,510,240
JBrowse link
G Trpm1 transient receptor potential cation channel, subfamily M, member 1 increases expression ISO manganese chloride results in increased expression of TRPM1 mRNA CTD PMID:17175027 NCBI chr 1:117,718,896...117,835,434
Ensembl chr 1:117,718,896...117,834,605
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 increases expression ISO manganese chloride results in increased expression of TRPM4 mRNA CTD PMID:17175027 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 decreases expression ISO manganese chloride results in decreased expression of TRPV3 mRNA CTD PMID:17175027 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link
G Tsga10 testis specific 10 increases expression ISO manganese chloride results in increased expression of TSGA10 mRNA CTD PMID:17175027 NCBI chr 9:39,991,203...40,098,259
Ensembl chr 9:39,991,830...40,098,232
JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 increases expression EXP manganese chloride results in increased expression of TSHZ1 mRNA CTD PMID:28801915 NCBI chr18:77,376,399...77,452,815
Ensembl chr18:77,377,394...77,453,509
JBrowse link
G Tshz2 teashirt zinc finger homeobox 2 increases expression ISO manganese chloride results in increased expression of TSHZ2 mRNA CTD PMID:17175027 NCBI chr 3:158,405,469...158,666,915
Ensembl chr 3:158,405,423...158,850,128
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression EXP manganese chloride results in increased expression of TSKU mRNA CTD PMID:28801915 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Tst thiosulfate sulfurtransferase decreases expression EXP manganese chloride results in decreased expression of TST mRNA CTD PMID:28801915 NCBI chr 7:109,948,061...109,955,378
Ensembl chr 7:109,948,062...109,957,216
JBrowse link
G Ttc13 tetratricopeptide repeat domain 13 increases expression EXP manganese chloride results in increased expression of TTC13 mRNA CTD PMID:28801915 NCBI chr19:52,637,599...52,692,196
Ensembl chr19:52,637,431...52,692,198
JBrowse link
G Ttc22 tetratricopeptide repeat domain 22 decreases expression EXP manganese chloride results in decreased expression of TTC22 mRNA CTD PMID:28801915 NCBI chr 5:121,401,973...121,423,130
Ensembl chr 5:121,406,326...121,423,130
JBrowse link
G Ttc8 tetratricopeptide repeat domain 8 increases expression EXP manganese chloride results in increased expression of TTC8 mRNA CTD PMID:28801915 NCBI chr 6:118,198,186...118,252,422
Ensembl chr 6:118,198,201...118,252,418
JBrowse link
G Ttc9b tetratricopeptide repeat domain 9B increases methylation
increases expression
EXP manganese chloride results in increased methylation of TTC9B gene
manganese chloride results in increased expression of TTC9B mRNA
CTD PMID:28801915 NCBI chr 1:82,953,434...82,955,659
Ensembl chr 1:82,953,434...82,955,616
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO manganese chloride results in decreased expression of TUBB3 protein CTD PMID:35063473 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP manganese chloride results in increased expression of TXNRD1 mRNA CTD PMID:22281203 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO
EXP
manganese chloride results in decreased expression of TYRP1 mRNA CTD PMID:17175027 PMID:26745496 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link
G Uap1 UDP-N-acetylglucosamine pyrophosphorylase 1 increases expression EXP manganese chloride results in increased expression of UAP1 mRNA CTD PMID:28801915 NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
JBrowse link
G Uap1l1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 increases expression EXP manganese chloride results in increased expression of UAP1L1 mRNA CTD PMID:28801915 NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO manganese chloride results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636
JBrowse link
G Ubap1 ubiquitin-associated protein 1 increases expression EXP manganese chloride results in increased expression of UBAP1 mRNA CTD PMID:28801915 NCBI chr 5:56,520,722...56,561,153
Ensembl chr 5:56,520,743...56,561,152
JBrowse link
G Ubb ubiquitin B increases expression EXP manganese chloride results in increased expression of UBB mRNA CTD PMID:20737472 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
G Ubd ubiquitin D increases expression EXP manganese chloride results in increased expression of UBD mRNA CTD PMID:28801915 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 decreases expression EXP manganese chloride results in decreased expression of UCHL1 protein CTD PMID:20798247 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Upp1 uridine phosphorylase 1 increases expression EXP manganese chloride results in increased expression of UPP1 mRNA CTD PMID:28801915 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link
G Usp15 ubiquitin specific peptidase 15 decreases expression ISO manganese chloride results in decreased expression of USP15 mRNA CTD PMID:17175027 NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
JBrowse link
G Usp18 ubiquitin specific peptidase 18 increases expression EXP manganese chloride results in increased expression of USP18 mRNA CTD PMID:28801915 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
JBrowse link
G Usp43 ubiquitin specific peptidase 43 increases expression EXP manganese chloride results in increased expression of USP43 mRNA CTD PMID:28801915 NCBI chr10:52,549,200...52,611,168
Ensembl chr10:52,548,963...52,611,533
JBrowse link
G Usp45 ubiquitin specific peptidase 45 decreases expression ISO manganese chloride results in decreased expression of USP45 mRNA CTD PMID:17175027 NCBI chr 5:35,318,621...35,392,090
Ensembl chr 5:35,318,635...35,389,420
JBrowse link
G Utf1 undifferentiated embryonic cell transcription factor 1 increases expression EXP manganese chloride results in increased expression of UTF1 mRNA CTD PMID:28801915 NCBI chr 1:194,740,339...194,741,465
Ensembl chr 1:194,740,339...194,741,465
JBrowse link
G Uvrag UV radiation resistance associated multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of UVRAG mRNA; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of UVRAG mRNA] CTD PMID:31690173 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP manganese chloride results in increased expression of VCAM1 mRNA CTD PMID:28801915 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions
increases secretion
ISO
EXP
manganese chloride results in increased expression of VEGFA mRNA
Echinomycin inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]; HIF1A mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]
[Plant Extracts co-treated with manganese chloride] results in increased expression of VEGFA protein; ARNT gene mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]
manganese chloride results in increased expression of VEGFA mRNA alternative form
CTD PMID:17175027 PMID:17467022 PMID:19263519 PMID:26064043 PMID:28801915 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vegfc vascular endothelial growth factor C increases expression ISO manganese chloride results in increased expression of VEGFC mRNA CTD PMID:17467022 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
JBrowse link
G Vegfd vascular endothelial growth factor D increases expression ISO manganese chloride results in increased expression of VEGFD mRNA CTD PMID:17467022 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
G Vgf VGF nerve growth factor inducible increases methylation ISO manganese chloride results in increased methylation of VGF gene CTD PMID:27913844 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
JBrowse link
G Vhl von Hippel-Lindau tumor suppressor multiple interactions ISO manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; VHL protein affects the reaction [manganese chloride results in increased expression of HIF1A protein] CTD PMID:19263519 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377
JBrowse link
G Vim vimentin increases expression EXP manganese chloride results in increased expression of VIM mRNA CTD PMID:28801915 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vnn3 vanin 3 increases expression EXP manganese chloride results in increased expression of VNN3 mRNA CTD PMID:26745496 NCBI chr 1:21,571,364...21,583,626
Ensembl chr 1:21,571,364...21,583,626
JBrowse link
G Vof16 ischemia related factor vof-16 increases expression EXP manganese chloride results in increased expression of VOF16 mRNA CTD PMID:28801915 NCBI chr 8:41,953,062...41,955,169 JBrowse link
G Vom2r46 vomeronasal 2 receptor, 46 increases expression EXP manganese chloride results in increased expression of VOM2R46 mRNA CTD PMID:28801915 NCBI chr 2:148,628,229...148,667,383
Ensembl chr 2:148,627,250...148,667,584
JBrowse link
G Vom2r55 vomeronasal 2 receptor, 55 increases expression EXP manganese chloride results in increased expression of VOM2R55 mRNA CTD PMID:28801915 NCBI chr 7:12,980,159...13,046,003
Ensembl chr 7:12,980,030...13,046,244
JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A decreases expression ISO manganese chloride results in decreased expression of VPS13A mRNA CTD PMID:17175027 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555
JBrowse link
G Vstm5 V-set and transmembrane domain containing 5 decreases methylation EXP manganese chloride results in decreased methylation of VSTM5 gene CTD PMID:28801915 NCBI chr 8:12,080,019...12,100,443
Ensembl chr 8:12,080,203...12,100,427
JBrowse link
G Vwa7 von Willebrand factor A domain containing 7 increases expression EXP manganese chloride results in increased expression of VWA7 mRNA CTD PMID:28801915 NCBI chr20:3,794,991...3,805,646
Ensembl chr20:3,794,991...3,805,525
JBrowse link
G Wasf2 WASP family member 2 increases expression ISO manganese chloride results in increased expression of WASF2 mRNA CTD PMID:17467022 NCBI chr 5:145,336,817...145,402,041
Ensembl chr 5:145,336,842...145,399,242
JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 increases expression EXP manganese chloride results in increased expression of WFDC1 mRNA CTD PMID:28801915 NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108
JBrowse link
G Wfdc11 WAP four-disulfide core domain 11 increases expression EXP manganese chloride results in increased expression of WFDC11 mRNA CTD PMID:28801915 NCBI chr 3:153,397,585...153,406,407 JBrowse link
G Wfdc12 WAP four-disulfide core domain 12 increases expression EXP manganese chloride results in increased expression of WFDC12 mRNA CTD PMID:28801915 NCBI chr 3:152,861,461...152,862,784
Ensembl chr 3:152,862,341...152,862,690
JBrowse link
G Wfdc18 WAP four-disulfide core domain 18 increases expression EXP manganese chloride results in increased expression of WFDC18 mRNA CTD PMID:28801915 NCBI chr10:68,588,818...68,590,972
Ensembl chr10:68,588,818...68,589,671
JBrowse link
G Whamm WASP homolog associated with actin, golgi membranes and microtubules decreases expression EXP manganese chloride results in decreased expression of WHAMM mRNA CTD PMID:28801915 NCBI chr 1:135,526,363...135,557,091
Ensembl chr 1:135,526,386...135,554,759
JBrowse link
G Wif1 Wnt inhibitory factor 1 increases expression EXP manganese chloride results in increased expression of WIF1 mRNA CTD PMID:28801915 NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of WIPI1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of WIPI1 protein; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of WIPI1 mRNA]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of WIPI1 protein] CTD PMID:31690173 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 increases expression EXP manganese chloride results in increased expression of WNK4 mRNA CTD PMID:28801915 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Wnt10b Wnt family member 10B decreases expression EXP manganese chloride results in decreased expression of WNT10B mRNA CTD PMID:28801915 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
JBrowse link
G Wnt11 Wnt family member 11 increases expression EXP manganese chloride results in increased expression of WNT11 mRNA CTD PMID:28801915 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294
JBrowse link
G Wnt6 Wnt family member 6 decreases expression EXP manganese chloride results in decreased expression of WNT6 mRNA CTD PMID:28801915 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523
JBrowse link
G Wnt7b Wnt family member 7B increases expression EXP manganese chloride results in increased expression of WNT7B mRNA CTD PMID:28801915 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581
JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO manganese chloride results in decreased expression of WT1 mRNA CTD PMID:17175027 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
G Wwox WW domain-containing oxidoreductase increases expression EXP manganese chloride results in increased expression of WWOX mRNA CTD PMID:28801915 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
G Xbp1 X-box binding protein 1 increases splicing
multiple interactions
EXP manganese chloride results in increased splicing of XBP1 mRNA
[manganese chloride results in increased abundance of Manganese] which results in increased expression of XBP1 protein alternative form; [manganese chloride results in increased abundance of Manganese] which results in increased splicing of XBP1 mRNA; manganese chloride results in increased expression of and results in increased splicing of XBP1 mRNA; SNCA protein promotes the reaction [manganese chloride results in increased expression of and results in increased splicing of XBP1 mRNA]
CTD PMID:23934647 PMID:23948121 PMID:32574669 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Ythdc2 YTH N6-methyladenosine RNA binding protein C2 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of YTHDC2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of YTHDC2 protein; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA]; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein] CTD PMID:34822792 NCBI chr18:37,266,559...37,331,681
Ensembl chr18:37,265,836...37,331,023
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta affects methylation
decreases expression
ISO manganese chloride affects the methylation of YWHAZ gene
manganese chloride results in decreased expression of YWHAZ mRNA
CTD PMID:27913844 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
G Yy1 YY1 transcription factor multiple interactions ISO [manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]; [manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]; [manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to SLC1A2 promoter]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of and affects the localization of YY1 protein; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 mRNA]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 protein]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 mRNA]; alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 protein]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC1 protein]]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to SLC1A2 promoter]]; Hesperidin inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of and affects the localization of YY1 protein]; IkK-16 compound inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 mRNA]; IkK-16 compound inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 protein]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to HDAC3 protein]]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] promotes the reaction [YY1 protein binds to SLC1A2 promoter]]; silmitasertib inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of and affects the localization of YY1 protein] CTD PMID:34310962 PMID:34800614 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
JBrowse link
G Zbed5 zinc finger BED-type containing 5 increases expression EXP manganese chloride results in increased expression of ZBED5 mRNA CTD PMID:28801915 NCBI chr12:26,807,652...26,813,706
Ensembl chr12:26,807,600...26,813,664
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression EXP manganese chloride results in increased expression of ZBTB10 mRNA CTD PMID:28801915 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
JBrowse link
G Zbtb26 zinc finger and BTB domain containing 26 increases expression EXP manganese chloride results in increased expression of ZBTB26 mRNA CTD PMID:28801915 NCBI chr 3:21,195,319...21,207,925
Ensembl chr 3:21,195,319...21,207,942
JBrowse link
G Zbtb38 zinc finger and BTB domain containing 38 increases expression EXP manganese chloride results in increased expression of ZBTB38 mRNA CTD PMID:28801915 NCBI chr 8:97,284,617...97,288,518
Ensembl chr 8:97,280,993...97,485,625
JBrowse link
G Zbtb7c zinc finger and BTB domain containing 7C increases expression EXP manganese chloride results in increased expression of ZBTB7C mRNA CTD PMID:28801915 NCBI chr18:69,441,616...69,765,744
Ensembl chr18:69,441,616...69,765,297
JBrowse link
G Zfand2a zinc finger AN1-type containing 2A increases expression EXP manganese chloride results in increased expression of ZFAND2A mRNA CTD PMID:22281203 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
JBrowse link
G Zfp146 zinc finger protein 146 increases expression EXP manganese chloride results in increased expression of ZFP146 mRNA CTD PMID:28801915 NCBI chr 1:85,409,570...85,421,835
Ensembl chr 1:85,409,373...85,436,275
JBrowse link
G Zfp202 zinc finger protein 202 increases expression EXP manganese chloride results in increased expression of ZFP202 mRNA CTD PMID:28801915 NCBI chr 8:40,542,665...40,567,397
Ensembl chr 8:40,542,701...40,563,118
JBrowse link
G Zfp41 zinc finger protein 41 increases expression ISO manganese chloride results in increased expression of ZFP41 mRNA CTD PMID:17175027 NCBI chr 7:107,307,303...107,320,164
Ensembl chr 7:107,306,867...107,320,270
JBrowse link
G Zfp503 zinc finger protein 503 increases expression EXP manganese chloride results in increased expression of ZFP503 mRNA CTD PMID:28801915 NCBI chr15:2,313,060...2,316,848
Ensembl chr15:2,313,060...2,316,848
JBrowse link
G Zfp703 zinc finger protein 703 increases expression EXP manganese chloride results in increased expression of ZFP703 mRNA CTD PMID:28801915 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677
JBrowse link
G Zfp710 zinc finger protein 710 decreases expression EXP manganese chloride results in decreased expression of ZFP710 mRNA CTD PMID:28801915 NCBI chr 1:133,966,256...134,036,593
Ensembl chr 1:134,024,267...134,036,601
JBrowse link
G Zfp758 zinc finger protein 758 increases expression EXP manganese chloride results in increased expression of ZNF761 mRNA CTD PMID:28801915 NCBI chr 1:61,941,284...61,989,354
Ensembl chr 1:61,942,116...61,989,490
JBrowse link
G Zfp827 zinc finger protein 827 increases expression EXP manganese chloride results in increased expression of ZFP827 mRNA CTD PMID:28801915 NCBI chr19:28,720,568...28,887,381
Ensembl chr19:28,721,021...28,887,191
JBrowse link
G Zfr zinc finger RNA binding protein increases expression EXP manganese chloride results in increased expression of ZFR mRNA CTD PMID:28801915 NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:61,137,611...61,200,322
JBrowse link
G Zg16 zymogen granule protein 16 increases expression EXP manganese chloride results in increased expression of ZG16 mRNA CTD PMID:28801915 NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079
JBrowse link
G Zhx2 zinc fingers and homeoboxes 2 increases expression EXP manganese chloride results in increased expression of ZHX2 mRNA CTD PMID:28801915 NCBI chr 7:89,226,358...89,374,266
Ensembl chr 7:89,226,463...89,374,378
JBrowse link
G Zic2 Zic family member 2 decreases expression EXP manganese chloride results in decreased expression of ZIC2 mRNA CTD PMID:28801915 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522
JBrowse link
G Zic5 Zic family member 5 decreases expression EXP manganese chloride results in decreased expression of ZIC5 mRNA CTD PMID:28801915 NCBI chr15:99,558,285...99,567,023
Ensembl chr15:99,560,323...99,567,035
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    chemical entity 19867
      molecular entity 19867
        inorganic molecular entity 19675
          inorganic salt 15548
            inorganic chloride 8524
              manganese(II) chloride 1171
                manganese(II) chloride dihydrate 0
                manganese(II) chloride tetrahydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      halogen 18693
                        chlorine atom 18454
                          chlorine molecular entity 18480
                            elemental chlorine 8794
                              monoatomic chlorine 8761
                                chloride 8761
                                  chloride salt 8779
                                    inorganic chloride 8524
                                      manganese(II) chloride 1171
                                        manganese(II) chloride dihydrate 0
                                        manganese(II) chloride tetrahydrate 0
paths to the root