.
4-hydroxyphenyl retinamide - Ontology Report - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-hydroxyphenyl retinamide
go back to main search page
Accession:CHEBI:42588 term browser browse the term
Definition:A retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.
Synonyms:exact_synonym: 15-[(4-hydroxyphenyl)amino]retinal
 related_synonym: 4-HPR;   4-hydroxy(phenyl)retinamide;   Formula=C26H33NO2;   InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+;   InChIKey=AKJHMTWEGVYYSE-FXILSDISSA-N;   N-(4-Hydroxyphenyl)retinamide;   N-(4-hydroxyphenyl)all-trans retinamide;   SMILES=CC(\\C=C\\C1=C(C)CCCC1(C)C)=C/C=C/C(C)=C/C(=O)Nc1ccc(O)cc1;   all-trans-4'-Hydroxyretinanilide;   fenretinida;   fenretinide;   fenretinidum
 xref: CAS:65646-68-6;   DrugBank:DB05076;   KEGG:D04162
 xref_mesh: MESH:D017313
 xref: PDBeChem:FEN;   PMID:20878269;   PMID:20978709;   PMID:21241664;   PMID:21319187;   PMID:21674264;   PMID:21964808;   PMID:22094120;   PMID:22162577;   PMID:22183330;   PMID:22221098;   PMID:22280430;   PMID:22323082;   PMID:22350416;   PMID:22382323;   PMID:22387538;   Reaxys:5769490



show annotations for term's descendants           Sort by:


Your selection has 3996 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

  • Select a more specific term using the term browser
  • Download the entire list for this term
  • Display annotations for this term only (exclude descendants)



  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 20856
        role 20816
          chemical role 20394
            antioxidant 16461
              4-hydroxyphenyl retinamide 3996
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 20856
        subatomic particle 20854
          composite particle 20854
            hadron 20854
              baryon 20854
                nucleon 20854
                  atomic nucleus 20854
                    atom 20854
                      main group element atom 20777
                        p-block element atom 20777
                          carbon group element atom 20710
                            carbon atom 20704
                              organic molecular entity 20704
                                heteroorganic entity 20215
                                  organochalcogen compound 19902
                                    organooxygen compound 19804
                                      carbon oxoacid 19150
                                        carboxylic acid 19147
                                          carboacyl group 18082
                                            univalent carboacyl group 18082
                                              carbamoyl group 17918
                                                carboxamide 17918
                                                  monocarboxylic acid amide 15949
                                                    4-hydroxyphenyl retinamide 3996
    paths to the root