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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cilazapril
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Accession:CHEBI:3698 term browser browse the term
Definition:A pyridazinodiazepine resulting from the formal condensation of the carboxy group of cilazaprilat with ethanol. It is a drug used in the treatment of hypertension and heart failure.
Synonyms:exact_synonym: (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
 related_synonym: Cilazapril anhydrous;   Dynorm;   Formula=C22H31N3O5;   InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28)/t17-,18-,19-/m0/s1;   InChIKey=HHHKFGXWKKUNCY-FHWLQOOXSA-N;   Inhibace;   Ro 34-2848;   SMILES=C1CC[C@@H](C(N2N1CCC[C@H]2C(=O)O)=O)N[C@H](C(OCC)=O)CCC3=CC=CC=C3;   Vascace;   Vascase;   cilazaprilum
 xref: CAS:88768-40-5;   DrugBank:DB01340;   Drug_Central:641;   HMDB:HMDB0015433;   KEGG:D07699
 xref_mesh: MESH:D017315
 xref: PMID:18297254;   PMID:1836986;   PMID:21760854;   PMID:24383331;   PMID:24754013;   PMID:25272892;   PMID:28334985;   PMID:28445944;   PMID:31531043;   Wikipedia:Cilazapril


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Path 1
Term Annotations click to browse term
  CHEBI ontology 5150
    role 5117
      application 909
        pro-agent 40
          prodrug 23
            cilazapril 0
              cilazapril monohydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5150
    subatomic particle 5141
      composite particle 5141
        hadron 5141
          baryon 5141
            nucleon 5153
              atomic nucleus 5153
                atom 5141
                  main group element atom 5114
                    main group molecular entity 5124
                      s-block molecular entity 5046
                        hydrogen molecular entity 5050
                          hydrides 4670
                            inorganic hydride 426
                              pnictogen hydride 422
                                nitrogen hydride 423
                                  azane 415
                                    ammonia 415
                                      organic amino compound 308
                                        amino acid 180
                                          non-proteinogenic amino acid 7
                                            non-proteinogenic alpha-amino acid 6
                                              Cilazaprilat 0
                                                cilazapril 0
                                                  cilazapril monohydrate 0
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