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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tibolone
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Accession:CHEBI:32223 term browser browse the term
Definition:Estran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis.
Synonyms:exact_synonym: 17alpha-ethynyl-17beta-hydroxy-7alpha-methylestr-5(10)-en-3-one
 related_synonym: (17R)-17-hydroxy-7alpha-methyl-19-norpregn-5(10)-en-20-yn-3-one;   (7alpha,17alpha)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one;   (7alpha,17beta)-17-ethynyl-17-hydroxy-7-methylestr-5(10)en-3-one;   17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one;   Formula=C21H28O2;   InChI=1S/C21H28O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,13,17-19,23H,5-12H2,2-3H3/t13-,17-,18+,19-,20+,21+/m1/s1;   InChIKey=WZDGZWOAQTVYBX-XOINTXKNSA-N;   SMILES=[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])[C@H](C)CC1=C2CCC(=O)C1;   tibolona;   tibolonum
 xref: CAS:5630-53-5;   Drug_Central:2655;   KEGG:D01639
 xref_mesh: MESH:C027385
 xref: Patent:US3340279;   Patent:US3475465

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  CHEBI ontology 2
    role 2
      application 2
        pharmaceutical 2
          drug 2
            bone density conservation agent 0
              tibolone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 2
    subatomic particle 2
      composite particle 2
        hadron 2
          baryon 2
            nucleon 2
              atomic nucleus 2
                atom 2
                  main group element atom 2
                    p-block element atom 2
                      carbon group element atom 2
                        carbon atom 2
                          organic molecular entity 2
                            organic molecule 2
                              organic cyclic compound 2
                                organic polycyclic compound 0
                                  steroid 0
                                    hydroxy steroid 0
                                      17-hydroxy steroid 0
                                        17beta-hydroxy steroid 0
                                          tibolone 0
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