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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:GSK591
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Accession:CHEBI:230495 term browser browse the term
Definition:GSK591 (EPZ015866) is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5).
Synonyms:related_synonym: EPZ015866;   Formula=C22H28N4O2;   GSK3203591;   InChI=1S/C22H28N4O2/c27-20(15-26-11-9-16-4-1-2-5-18(16)14-26)13-24-22(28)17-8-10-23-21(12-17)25-19-6-3-7-19/h1-2,4-5,8,10,12,19-20,27H,3,6-7,9,11,13-15H2,(H,23,25)(H,24,28)/t20-/m0/s1;   InChIKey=TWKYXZSXXXKKJU-FQEVSTJZSA-N;   SMILES=O=C(C1=CC(NC2CCC2)=NC=C1)NC[C@H](O)CN3CC4=C(C=CC=C4)CC3
 xref: CAS:1616391-87-7;   PMCID:PMC6217072;   PMID:30461193;   PMID:31665911;   PMID:33495409;   PMID:33579912;   PMID:33664859;   PMID:33829865;   PMID:37963200;   PMID:38172189


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    chemical entity 19888
      atom 19888
        nonmetal atom 19811
          carbon atom 19763
            organic molecular entity 19763
              GSK591 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19888
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19888
              atomic nucleus 19888
                atom 19888
                  main group element atom 19827
                    p-block element atom 19827
                      carbon group element atom 19767
                        carbon atom 19763
                          organic molecular entity 19763
                            GSK591 0
paths to the root