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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:actinomycin X2
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Accession:CHEBI:180658 term browser browse the term
Definition:Actinomycin X2, is a chemotherapy medication used to treat a number of types of cancer and has strong antimicrobial activity against Gram-positive bacteria, including MRSA and non-MRSA. It is given by injection into a vein. Most people develop side effects. Common side effects include bone marrow suppression, vomiting, mouth ulcers, hair loss, liver problems, infections, and muscle pains. Other serious side effects include future cancers, allergic reactions, and tissue death at the site of injection. Use in pregnancy may harm the baby. It is in the cytotoxic antibiotic family of medications. It is believed to work on DNA and Isoleucyl-tRNA synthetase (IleRS).
Synonyms:related_synonym: Formula=C62H84N12O17;   InChI=1S/C62H84N12O17/c1-26(2)42-59(85)73-21-17-18-36(73)57(83)69(13)24-38(76)71(15)49(29(7)8)62(88)90-33(12)45(56(82)65-42)68-54(80)40-41(63)50(78)31(10)52-47(40)64-46-35(20-19-30(9)51(46)91-52)53(79)67-44-32(11)89-61(87)48(28(5)6)72(16)39(77)25-70(14)58(84)37-22-34(75)23-74(37)60(86)43(27(3)4)66-55(44)81/h19-20,26-29,32-33,36-37,42-45,48-49H,17-18,21-25,63H2,1-16H3,(H,65,82)(H,66,81)(H,67,79)(H,68,80)/t32-,33-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1;   InChIKey=ZGROOAYIFKLEPE-IRFLANFNSA-N;   SMILES=[H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)C1=C(N)C(=O)C(C)=C3Oc4c(C)ccc(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CC(=O)CN6C(=O)[C@H](NC5=O)C(C)C)c4N=C13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    chemical entity 19897
      atom 19897
        nonmetal atom 19819
          carbon atom 19772
            organic molecular entity 19772
              actinomycin X2 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            actinomycin X2 0
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