TRBV7-8 (T cell receptor beta variable 7-8) - Rat Genome Database

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Gene: TRBV7-8 (T cell receptor beta variable 7-8) Homo sapiens
Analyze
No known orthologs.
Symbol: TRBV7-8
Name: T cell receptor beta variable 7-8
RGD ID: 1342684
HGNC Page HGNC:12242
Description: Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane.
Type: gene
RefSeq Status: VALIDATED
Previously known as: TCRBV6S2A1N1T; TCRBV7S8; TRBV78
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Annotation category: only annotated on alternate loci in reference assembly
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh377142,099,455 - 142,099,938 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367141,900,477 - 141,900,960 (+)NCBINCBI36Build 36hg18NCBI36
Celera7137,030,961 - 137,031,444 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,548,096 - 136,548,579 (+)NCBIHuRef
T2T-CHM13v2.07143,868,760 - 143,869,243 (+)NCBIT2T-CHM13v2.0


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:3865189   PMID:8650574   PMID:9074928   PMID:21873635   PMID:26408818  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh37/hg19 7q34(chr7:141937588-142486548)x3 copy number gain See cases [RCV000143759] Chr7:141937588..142486548 [GRCh37]
Chr7:141584062..142186550 [NCBI36]
Chr7:7q34		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:214
Count of miRNA genes:199
Interacting mature miRNAs:205
Transcripts:ENST00000390359
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
GDB:201761  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377142,099,694 - 142,099,883UniSTSGRCh37
Build 367141,900,532 - 141,900,721RGDNCBI36
Celera7137,031,016 - 137,031,205RGD
Cytogenetic Map7q34UniSTS
HuRef7136,548,151 - 136,548,340UniSTS
CRA_TCAGchr7v27141,592,262 - 141,592,451UniSTS


Expression

RNA-SEQ Expression


Sequence


Protein Sequences
GenBank Protein A0A1B0GX51 (Get FASTA)   NCBI Sequence Viewer  
  AAA60702 (Get FASTA)   NCBI Sequence Viewer  
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A1B0GX51-F1-model_v2 AlphaFold A0A1B0GX51 1-115 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:12242 AgrOrtholog
COSMIC TRBV7-8 COSMIC
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
GTEx TRBV7-8 GTEx
HGNC ID HGNC:12242 ENTREZGENE
Human Proteome Map TRBV7-8 Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  TCR_beta_variable UniProtKB/Swiss-Prot
NCBI Gene TRBV7-8 ENTREZGENE
PANTHER T CELL RECEPTOR BETA VARIABLE 7-4-RELATED UniProtKB/Swiss-Prot
  T-CELL RECEPTOR BETA CHAIN UniProtKB/Swiss-Prot
Pfam V-set UniProtKB/Swiss-Prot
PharmGKB PA36922 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot
SMART IGv UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A1B0GX51 ENTREZGENE, UniProtKB/Swiss-Prot