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Pathways

Ar target genes

The androgen receptor regulates the expression of genes belonging to many functional classes – see PMID 18008377. Several target genes are listed with aliases in parentheses, full names and links to gene report pages:

Cdkn1a (Cip1, Waf1) – cyclin-dependent kinase inhibitor 1A
CYP3A5 (PCN3, P450PCN3) – cytochrome P450 family 3 subfamily A member 5
Fkbp5 (Fkbp51) – FK506 binding protein 5
Igfbp3 (Igfbp-3, Igf-Bp3) – insulin-like growth factor binding protein 3
Klkb1 (Klk3) – kallikrein B1
Mmp2 (mmp-2) matrix metallopeptidase 2
Acpp (Pap, Acpp11) – acid phosphatase, prostate
Scap – SREBF chaperone


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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.