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Strain Registration

Strain: TM-Prkdcem4KyoIl2rgem5Kyo

Symbol: TM-Prkdcem4KyoIl2rgem5Kyo
Strain: TM-Prkdcem4Il2rgem5
Substrain: Kyo
RGD ID: 11040950
Citation ID: RRID:RGD_11040950
Ontology ID: RS:0004141
Alleles: Il2rg;   Il2rgem5Kyo;   Prkdcem4Kyo;   Prkdc
Also Known As: TM-Prkdcem4KyoIl2rgem5Kyo; TM-DSCID; NBRP Rat No: 0648; TM-Prkdc^[em4Kyo]Il2rg^[em5Kyo]
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: This strain was established by Zinc-finger nucleases (ZFNs) method causing 20-bp deletion in the exon1 of Prkdc gene and a 653-bp deletion Il2rg gene. Background strain: TM/Kyo
Coat Color: Albino
Last Known Status: Cryopreserved Sperm (as of 2017-07-12)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81198,544,952 - 98,762,499RGD_MAPPER_PIPELINE
GRCr8X70,435,340 - 70,439,052RGD_MAPPER_PIPELINE
mRatBN7.21185,040,790 - 85,258,357RGD_MAPPER_PIPELINEmRatBN7.2
mRatBN7.2X66,395,330 - 66,399,026RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01189,293,547 - 89,510,948RGD_MAPPER_PIPELINERnor_6.0
Rnor_6.0X71,165,378 - 71,169,078RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.0X72,017,856 - 72,021,516RGD_MAPPER_PIPELINERnor_5.0
Rnor_5.01192,347,175 - 92,565,022RGD_MAPPER_PIPELINERnor_5.0
RGSC_v3.4X89,342,055 - 89,345,715RGD_MAPPER_PIPELINERGSC_v3.4
RGSC_v3.41186,951,420 - 87,169,229RGD_MAPPER_PIPELINERGSC_v3.4






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This strain shows severe combined immunodeficiency＿SCID＿and growth retardation caused by a 20-bp deletion in the exon 1 of Prkdc gene and a 653-bp deletion in Il2rg gene 1302502
strain_reproduction maintained by mating between Il2rg-homozygous/Prkdc-heterozygous rats 1302502