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Gene: Rimbp2 (RIMS binding protein 2) Rattus norvegicus

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Symbol:

Rimbp2

Name:

RIMS binding protein 2

RGD ID:

708533

Description:

Enables protein-macromolecule adaptor activity. Predicted to be involved in neuromuscular synaptic transmission; regulation of calcium-dependent activation of synaptic vesicle fusion; and regulation of presynaptic membrane potential. Predicted to be located in plasma membrane and synapse. Predicted to be active in calyx of Held; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Orthologous to human RIMBP2 (RIMS binding protein 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC266780; Rbp2; RIM binding protein 2; RIM-BP2; RIMS-binding protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RIMBP2 (RIMS binding protein 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Rimbp2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rimbp2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RIMBP2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RIMBP2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rimbp2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RIMBP2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RIMBP2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rimbp2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rimbp2 (RIMS binding protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GPR12 (G protein-coupled receptor 12)	HGNC	OMA
Homo sapiens (human):	OASL (2'-5'-oligoadenylate synthetase like)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Rimbp2 (RIMS binding protein 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	RIMBP2 (RIMS binding protein 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rimbp2 (RIMS binding protein 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rimbp2 (RIMS binding protein 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rimb-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	rimb-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Rbp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	rimbp2a	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	rimbp2a	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	rimbp2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	33,383,646 - 33,582,259 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	33,384,007 - 33,593,999 (+)	Ensembl				GRCr8
mRatBN7.2	12	27,747,615 - 27,946,256 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	27,747,980 - 27,956,763 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	28,962,795 - 29,085,556 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	29,573,367 - 29,696,125 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	28,556,444 - 28,754,898 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	31,393,229 - 31,605,567 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	31,530,699 - 31,620,760 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	33,319,996 - 33,529,398 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	28,809,987 - 29,012,169 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	29,442,290 - 29,640,007 (+)	NCBI		Celera
RGSC_v3.1	12	28,851,920 - 28,872,012 (+)	NCBI
Cytogenetic Map	12	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,4-methylenedioxymethamphetamine (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

alpha-Zearalanol (EXP)

amitrole (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

CGP 52608 (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

fulvestrant (ISO)

genistein (EXP)

lead(0) (ISO)

malathion (ISO)

methimazole (EXP)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

nickel atom (ISO)

paracetamol (EXP)

perfluorooctanoic acid (EXP)

permethrin (EXP)

poly(I:C) (EXP)

progesterone (ISO)

pyrethrins (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (EXP,ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

maintenance of presynaptic active zone structure (IEA)

neuromuscular synaptic transmission (IBA)

regulation of calcium-dependent activation of synaptic vesicle fusion (ISO)

regulation of presynaptic cytosolic calcium ion concentration (IEA)

regulation of presynaptic membrane potential (ISO)

Cellular Component

calyx of Held (IEA,ISO)

glutamatergic synapse (ISO)

plasma membrane (IEA)

presynaptic active zone cytoplasmic component (ISO)

synapse (IEA)

synaptic ribbon (ISO)

Molecular Function

protein binding (IPI,ISO)

protein-macromolecule adaptor activity (IDA)

structural constituent of presynaptic active zone (ISO)

voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels (IEA,ISO)

voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	RBP2 stabilizes slow Cav1.3 Ca2+ channel inactivation properties of cochlear inner hair cells.	Ortner NJ, etal., Pflugers Arch. 2020 Jan;472(1):3-25. doi: 10.1007/s00424-019-02338-4. Epub 2019 Dec 17.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins.	Wang Y, etal., J Biol Chem 2000 Jun 30;275(26):20033-44.

Additional References at PubMed

PMID:15057822	PMID:17855024	PMID:19389623	PMID:22871113	PMID:27671655	PMID:30661983

Genomics

Comparative Map Data

Rimbp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	33,383,646 - 33,582,259 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	33,384,007 - 33,593,999 (+)	Ensembl				GRCr8
mRatBN7.2	12	27,747,615 - 27,946,256 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	27,747,980 - 27,956,763 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	28,962,795 - 29,085,556 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	29,573,367 - 29,696,125 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	28,556,444 - 28,754,898 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	31,393,229 - 31,605,567 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	31,530,699 - 31,620,760 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	33,319,996 - 33,529,398 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	28,809,987 - 29,012,169 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	29,442,290 - 29,640,007 (+)	NCBI		Celera
RGSC_v3.1	12	28,851,920 - 28,872,012 (+)	NCBI
Cytogenetic Map	12	q13	NCBI

RIMBP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	130,396,133 - 130,716,299 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	130,396,131 - 130,768,228 (-)	Ensembl			hg38	GRCh38
GRCh37	12	130,880,678 - 131,200,844 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	129,446,634 - 129,568,363 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	12	130,494,857 - 130,616,297 (-)	NCBI		Celera
Cytogenetic Map	12	q24.33	NCBI
HuRef	12	127,866,583 - 127,988,111 (-)	NCBI		HuRef
CHM1_1	12	130,700,550 - 130,823,261 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	130,433,406 - 130,754,746 (-)	NCBI		T2T-CHM13v2.0

Rimbp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	128,834,852 - 129,030,636 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	128,834,855 - 129,030,550 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	128,757,788 - 128,953,644 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	128,757,791 - 128,953,486 (-)	Ensembl			mm10	GRCm38
MGSCv37	5	129,266,276 - 129,459,237 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	129,072,499 - 129,268,070 (-)	NCBI		MGSCv36	mm8
MGSCv36	5	127,024,716 - 127,087,061 (-)	NCBI		MGSCv36	mm8
Celera	5	125,792,301 - 125,891,098 (-)	NCBI		Celera
Cytogenetic Map	5	G1.3	NCBI
cM Map	5	67.91	NCBI

Rimbp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	1,332,778 - 1,428,748 (+)	Ensembl
ChiLan1.0	NW_004955482	1,326,628 - 1,431,358 (+)	NCBI	ChiLan1.0	ChiLan1.0

RIMBP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	138,456,797 - 138,782,376 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	138,453,316 - 138,848,361 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	128,009,575 - 128,338,009 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	132,222,052 - 132,538,029 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	132,225,056 - 132,305,103 (-)	Ensembl			panPan2	panpan1.1

RIMBP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	1,519,489 - 1,744,011 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	1,645,591 - 1,744,020 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	1,719,625 - 1,944,681 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	1,765,398 - 1,991,479 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	1,765,218 - 2,010,409 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	1,827,412 - 1,926,413 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	1,798,409 - 2,023,366 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	1,706,066 - 1,932,688 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rimbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	123,214,028 - 123,318,323 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936660	1,435,019 - 1,482,958 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936660	1,433,535 - 1,601,912 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RIMBP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	24,394,750 - 24,722,235 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	24,394,793 - 24,722,237 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	26,227,904 - 26,295,566 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RIMBP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	125,770,331 - 126,170,664 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666037	118,919,840 - 119,239,707 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rimbp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	27,108,508 - 27,144,190 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624747	27,107,951 - 27,245,303 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rimbp2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	25,106,394 - 25,212,223 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rimbp2
1230 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	2592
Count of miRNA genes:	352
Interacting mature miRNAs:	490
Transcripts:	ENSRNOT00000033379, ENSRNOT00000067867
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	24805022	52308831	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	50386405	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	25989355	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
70169	Eae13	Experimental allergic encephalomyelitis QTL 13		0.032	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	12	29775522	42298555	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	28717718	49212240	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	18749469	36488809	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	18749469	34312613	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	29636637	37764351	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	7901625	33938215	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	33700556	Rat

Markers in Region

BE097070

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	27,926,789 - 27,926,949 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	31,586,102 - 31,586,261	NCBI	Rnor6.0
Rnor_6.0	12	31,570,753 - 31,570,912	NCBI	Rnor6.0
Rnor_5.0	12	33,509,936 - 33,510,095	UniSTS	Rnor5.0
Rnor_5.0	12	33,497,812 - 33,497,971	UniSTS	Rnor5.0
RGSC_v3.4	12	28,992,643 - 28,992,802	UniSTS	RGSC3.4
Celera	12	29,620,473 - 29,620,632	UniSTS
RH 3.4 Map	12	462.2	UniSTS
Cytogenetic Map	12	q14	UniSTS

BG381331

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	27,805,719 - 27,805,873 (+)	MAPPER	mRatBN7.2
mRatBN7.2	5	152,287,859 - 152,288,013 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	158,503,116 - 158,503,269	NCBI	Rnor6.0
Rnor_6.0	12	31,451,559 - 31,451,712	NCBI	Rnor6.0
Rnor_5.0	12	33,379,165 - 33,379,318	UniSTS	Rnor5.0
Rnor_5.0	5	162,230,100 - 162,230,253	UniSTS	Rnor5.0
RGSC_v3.4	5	158,819,605 - 158,819,758	UniSTS	RGSC3.4
RGSC_v3.4	12	28,870,401 - 28,870,554	UniSTS	RGSC3.4
Celera	12	29,500,218 - 29,500,371	UniSTS
Celera	5	150,657,808 - 150,657,961	UniSTS
RH 3.4 Map	5	1046.8	UniSTS
Cytogenetic Map	5	q36	UniSTS
Cytogenetic Map	12	q14	UniSTS

BF386435

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	27,811,031 - 27,811,225 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	31,457,271 - 31,457,464	NCBI	Rnor6.0
Rnor_5.0	12	33,384,330 - 33,384,523	UniSTS	Rnor5.0
RGSC_v3.4	12	28,875,671 - 28,875,864	UniSTS	RGSC3.4
Celera	12	29,505,489 - 29,505,682	UniSTS
RH 3.4 Map	12	461.0	UniSTS
Cytogenetic Map	12	q14	UniSTS

BE105245

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	27,946,055 - 27,946,206 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	31,605,367 - 31,605,517	NCBI	Rnor6.0
Rnor_5.0	12	33,529,201 - 33,529,351	UniSTS	Rnor5.0
RGSC_v3.4	12	29,011,972 - 29,012,122	UniSTS	RGSC3.4
Celera	12	29,639,810 - 29,639,960	UniSTS
RH 3.4 Map	12	468.7	UniSTS
Cytogenetic Map	12	q14	UniSTS

BF399187

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	27,810,948 - 27,811,167 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	31,457,188 - 31,457,406	NCBI	Rnor6.0
Rnor_5.0	12	33,384,247 - 33,384,465	UniSTS	Rnor5.0
RGSC_v3.4	12	28,875,588 - 28,875,806	UniSTS	RGSC3.4
Celera	12	29,505,406 - 29,505,624	UniSTS
RH 3.4 Map	12	460.8	UniSTS
Cytogenetic Map	12	q14	UniSTS

BF390440

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	27,945,316 - 27,945,480 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	31,604,628 - 31,604,791	NCBI	Rnor6.0
Rnor_5.0	12	33,528,462 - 33,528,625	UniSTS	Rnor5.0
Celera	12	29,639,071 - 29,639,234	UniSTS
RH 3.4 Map	12	506.8	UniSTS
Cytogenetic Map	12	q14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	157	71	70	39	35	39	6	278	134	11	131	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598282	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598283	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598284	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC118310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF199336	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033379 ⟹ ENSRNOP00000030915

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,536,165 - 33,592,765 (+)	Ensembl
mRatBN7.2 Ensembl	12	27,900,155 - 27,956,763 (+)	Ensembl
Rnor_6.0 Ensembl	12	31,530,699 - 31,602,083 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000067867 ⟹ ENSRNOP00000059643

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,384,007 - 33,592,765 (+)	Ensembl
mRatBN7.2 Ensembl	12	27,747,980 - 27,956,763 (+)	Ensembl
Rnor_6.0 Ensembl	12	31,530,699 - 31,602,565 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086078 ⟹ ENSRNOP00000073070

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,494,194 - 33,582,255 (+)	Ensembl
mRatBN7.2 Ensembl	12	27,747,980 - 27,946,253 (+)	Ensembl
Rnor_6.0 Ensembl	12	31,536,951 - 31,620,760 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100361 ⟹ ENSRNOP00000080836

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,384,007 - 33,582,259 (+)	Ensembl
mRatBN7.2 Ensembl	12	27,747,980 - 27,946,253 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107331 ⟹ ENSRNOP00000097882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,384,007 - 33,582,259 (+)	Ensembl
mRatBN7.2 Ensembl	12	27,747,980 - 27,946,253 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115151 ⟹ ENSRNOP00000087009

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,520,049 - 33,579,779 (+)	Ensembl
mRatBN7.2 Ensembl	12	27,884,038 - 27,944,846 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000158624 ⟹ ENSRNOP00000111280

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	33,494,194 - 33,593,999 (+)	Ensembl

RefSeq Acc Id:

NM_001100488 ⟹ NP_001093958

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,383,793 - 33,582,259 (+)	NCBI
mRatBN7.2	12	27,747,760 - 27,946,253 (+)	NCBI
Rnor_6.0	12	31,393,229 - 31,605,564 (+)	NCBI
Rnor_5.0	12	33,319,996 - 33,529,398 (+)	NCBI
RGSC_v3.4	12	28,809,987 - 29,012,169 (+)	RGD
Celera	12	29,442,290 - 29,640,007 (+)	RGD

Sequence:

show sequence

GTGTGTGTGTATGTGTGTGTGAAAACACTGCCGTTTCCAAGCTTTGGCTACTGCTCTCTGGCGG
GTGGCTCTTGCTCATGCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCCCCTGCAAAAATTAAATGGATAATTTCTAGCTGATTCCAA
GTGGTGCCCACACACCCGTGTCCTTCAGTGTTGATTGGATCTCTCTCTCTCTCTCTCTCTCTCT
CTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCCCTCTCTCTCTCCCCACTCTCTTCACTCT
CCTCCCCTCCCTCTGGCCCCAGTTTGTAATCTGACACAGTGCACTGCAGTGGCTGTCTCTGTCT
CTCTCTGGGAGCCCTGGAGGCTGGGCACCGAGAACATCCAAGGAAGATGAACTAAAGGCTTCTG
TGCAGAGGGAGCATCGCCTGAGGCCCCTGGAAAGGCCTTCCCTTGAGGGCCCGGCAGCATGACC
AGGTGAAGGCCGAACATGCCTGGCTCTCCGTGGTGACCTGAGAGGAGAGTTCGATTCGCTGTGA
GGGAGAAACGCCAGCTCCAAGCCAAACTGGAGAACTTGGAACAGGTCCTGAAGCATATGCGAGA
GGCTGCTGAGCGAAGGCAACAGCTGGAGTTGGAGCATGAGCAAGCCCTGGCCATTCTCAATGCC
AAGCAGCAGGAGATCCAGCTTCTGCAGCAGGCTCAGGTTGAAGCTAAGAAAGAGCATGAAGGGG
CTGTACAGCTGTTAGAGAACACCCTGGACTGCATGCAGTCCAAGGTCCGAGAGCTGGAAGAGAA
ATGCCGTGTGCAAAGCGAGCAGTTTAACCTGTTGTCCCGGGACCTGGAGAAGTTCCGGCAACAC
GCTGGGAGTATTGACCTGCTGGGAAGCAACTCAGTGGCCTTGCTGGATGTCCCTCTGGCCCCTG
GCAAGCCTTTCTCACAGTACATGAATGGACTAGCCACTTCCATCCACAAAGGTCACGAGGGCCC
CACCGGACACTACTCTGTGATTGGTGACTATATCCCGCTGTCTGGGGACAAGCTGGAGTCTCCG
TGTGTGAAGCCCTCCTTCCTGTTGAGATCCAGCAGCCCAAGATGCAGATTTGAGTCCGAGATGG
ACGATGACCGGAGCTCTAACAAGTCCAAGCACAGCAGCTCGGGGAAGGTGCACCTGTGTGTGGC
CCGCTACAGTTACAACCCCTTCGATGGGCCCAATGAGAACCCGGAAGCGGAGCTGCCTCTCACG
GCGGGAAAGTATCTCTACGTCTATGGGGACATGGATGAAGATGGGTTCTACGAAGGAGAACTTT
TGGATGGGCAGAGGGGCTTGGTGCCGTCCAACTTTGTGGATTTTATCCAGGACAACGAGTCACG
GTTCGCTGGCACTCTGGGGAGTGAGCAGGACCAGAACTTTCTCAACCACTCTGGCATCAGTCTG
GAACGCGACAGCATCCTTCACCTCCACTCTCCAACTCAAGTGGACTCGGGGATCACTGACAATG
GTGGGGGAACCCTGGACGTGAACATCGATGACATCGGAGAAGACATTGTGCCTTACCCTAGGAA
AATCACCCTCATCAAACAGCTTGCCAAAAGTGTCATCGTGGGCTGGGAGCCCCCTGCCGTGCCT
CCCGGCTGGGGCACCGTGAGCAGTTATAATGTGCTGGTGGACAAAGAGACACGAATGAGCCTTG
CCCTGGGTAGGAGAACTAAGGCGCTAATCGAGAAACTTAACACAGCCGCCTGCACCTACCGCAT
CTCCGTGCAGTGCGTCACGAGCCGGGGTAACTCGGACGAGCTGCAATGCACACTGCTGGTGGGC
AAGGATGTGGTGGTGGCACCATCCCAGCTGCGTGTGGACAACATCACACAGATCTCCGCCCAGC
TCTCGTGGCTGCCGACCAACAGTAACTACAGCCATATCATCTTCCTCAATGAAGAGGAATTGGA
CATCGTGAAGGCAGCCAGGTACAAGTATCAATTCTTCAACCTCAGGCCTAATATGGCCTACAAG
GTGAAGGTCTTGGCCCAGCCACACCAGATGCCCTGGCAGCTGCCGCTGGAGCAGAGAGAAAAGA
AGGAGGCCTGTGTGGAGTTCTCCACGCTGCCTGCAGGCCCTCCGGCCCCGCCACAAGACGTCAC
CGTCCAAGCTGGGGCCACCACTGCCTCCGTTCAGGTCTCCTGGAAGCCCCCTGCACTGACTCCC
ACTGGGTTGTCCAATGGAGCAAATGTCACAGGATATGGCGTGTACGCCAAAGGGCAGAGGGTGG
CTGAAGTCATCGCCCCCACAGCAGATGGCGCGGCAGTGGAGCTGGTCCGGCTGCGCAGCCTGGA
GGCCAAGGCCGTGAGTGTGCGCACCCTGTCCGCACAGGGAGAGTCCATGGATTCTGCCCTCGCT
GCCATCCCCCCTGACCTCCTGGTGCCTCCAGCCCCCCACCCGAGGACTGCTCCCCCACCAAAGC
CATTAGCAAGTGACATGGATACCAAAGACCTGGGTCCCCACGTCAAAGTGGATGAGTCCTGGGA
GCAGAGCCGGCCACCGGGCCCTGCTCATGGCCACATGTTGGAACCACCTGACATGCATAGCACT
GGCCCTGGCAGAAGGTCACCCTCGCCCAGCCGGATCCTTCCTCAGCCACAAGGAGCCCCTGTGT
CAACCACCGTCGCCAAGGCCATGGCCCGTGAAGCTGCACAGAGGGTAGCTGAGAGCAACAGGTT
AGAGAAAAGGAGCCTCTTTTTAGAGCAAAGCAGTGCTGGGCCGTACGCCAACTCAGACGAGGAG
GATGGCTATGCCTCCCCTGAGGTCAAGAGGAGAGGCACATCGGTGGATGACTTCCTGAAAGGGT
CAGAGCTGGGCCAGCAGCCTCACTGTTGCCATGGAGATGAGTACCACACAGAGAGCAGCCGGGG
GTCAGACCTGTCGGACATCATGGAGGAAGATGAGGAGGAGCTATACTCAGAGATGCAGCTGGAG
GATGGGGGCCGGCGTCGGCCCAGCGGTACCTCTCACAACGCCCTCAAGATTTTAGGAAACTCCG
CCTTGATGGGACGAGGAGACCGGATGGAGCATGTGAGCCGAAGGTATTCGCACAGCGGCGGAGG
TCCTCAGAGACATAGGCCGATGGCTCCATCCATTGATGAATACACGGGGCGAGACCATCTTTCT
CCAGACTTCTATGACGAGTCAGAAACGGACCCCGGTGCTGAGGAGCTCCCGGCCCGCATCTTCG
TTGCTCTGTTTGACTATGACCCGCTCACCATGTCCCCAAACCCGGATGCTGCCGAAGAGGAGCT
GCCCTTCAAAGAAGGACAGATCATCAAGGTATATGGAGACAAAGACGCAGATGGCTTCTACCGT
GGGGAGACCTGTGCCAGGCTCGGCCTCATTCCCTGTAACATGGTCTCCGAGATCCATGCGGATG
ATGAGGAGATGATGGACCAGCTGCTGAGACAAGGCTTCCTCCCTCTGAACACACCCGTGGAGAA
AATAGAGAGAAGTAGAAGAAGCGGCCGGGGTCACTCTGTACCCACACGGAGAATGGTGGCTCTC
TACGACTATGACCCTCGGGAAAGCTCCCCTAACGTGGACGTTGAGGCTGAACTTCTGTTTTGCA
CAGGAGACATTATTACTGTTTTTGGTGAAATCGATGAAGACGGGTTTTATTACGGAGAGCTGAA
TGGGCAGAAAGGCCTCGTGCCTTCCAATTTCCTGGAAGAAGTGCCTGATGACGTGGAGGTCCAC
CTTTCCGATGCTCCGCCCCACTACTCCCACGACCCGCCCATGCGCACCAAGGCCAAAAGGAAGA
AGAGTGTTCATTTCACACCCTAATCAGGCATGTAGCCTTCACGTAAGTCAGCAACCGAAGACAC
CTTAGAGAGATACCGACTTAAGCTACCCTAAGCGGACAGCACGGTAGTCTTAAGACTTCAATGT
GGGCTTAAAGAAAGAGAGAGAAAAGAAATATGTCTCAAAAAAAAAAAAACAAACCCATTGGACC
TAAAGTATTAGGCTATCTCACCTGGTCTCAGCTGCCAGGCAACCGGATTCATAGTGAAACGAAT
CATCTCGAACAATTTTTTTTTTATAAATATGTCCATTGAGAATATGGGAAAGGCCAACCTTGGG
AACATATTTCTTAAAGCTGTTTGTTTACACAAGAGTGCGCCAGCGTGTACTCACAAGGAGAGCT
GCCTATTGCATTGTAAGCTGCCCTCGGTAAAAAGCACAACCGAACCCATGTGTTTACGGTAGCA
GGTTTGACTCCTGAGAGCCGAGACAAAACTTTAATCCCAGATCATGCCCTGAGGGGTGGCCTTG
GCTCTGGGCATGCCAAAGCTGGCCGGAACACCCAGCTGCAGCCCCTTGGCCTTAGGAGCAAGAA
GGTGTTCCCTCTCCTCAAAGCACAATCGTTCAGAGCTCATGGAGGTGCAGGCGAGGTGCTGGCA
TTACTAATGCAATACTGTCTCCGGACGTGGCAGCTCCCATGACGTCATAGCTGGCCCCATGGTA
TCTTCAGGTGTGCTTTGGGTGCGCCCTAGGTGTTCTCCATTAGAGTTAGACCTTGATTTTAAAT
CCAAGCAAGCTTGGGGGCCCCTTGCCTTGTATGGTATGGTACGCTCACTGAGTGCCTGGGTCTC
GCTTTGCCAACTCTTGCTCTGGGGACATTAGTGAACCAGAGGCCTGGCAATTACTAGCCACGCT
CAGGCGTGTGCCGAGCTGCAGATTGAAGTAAAATTGGCACTCAGTGTTTCGGAATCAAATCCCA
CCCCTTCGAAGCACCGTTGGTCGGCCACCTAAAGTCTCTCAAAGCCCACCATCTCTCTCTGTGC
TGGGGAAAAGATGTACTCCTCTATTGGGAATGGCGAGAGTCTTCAAGAAGGGCCTTTGAGCTTC
CTTAGATTACAATTAAGGTTCATTTCAGTTTTTTTTCTTTCAAACAGTGTGCCATCCCCCAAAG
TTTCTGTAGGACTAACCCAAGGGCTCACTCCCCACGGCAAGGTCTTATCTACCATCTAGTTCAC
GATCCATCCAAATTCCCACGGAGAGCTTTTTTCCTTTACAATGATTGATGGGTATCTCGGCCAC
TTTACCTATCCATCTGATTGACAATAACCTCCCCTGCTTTTAGTCTGAATTTTCAGAGTAAATT
ATGACCTGGCTTTCTTTGCCAAAGCGATGGCCACCCCGCCTCCCAAGACAAAGACCGCGAAAGC
CCATGGAGGGCCAGCCCCTCTCTCTCTCAGAGGGGCCTTGGGAGCGGGCGTGTGTTTCTCATGG
CATACTTTAAAAATTGAAAGAAGAAACGAACCACCACCCACCCTTTCCCCTGGCTGGCGGGAGA
CGGGGCAGTGTTACCGAGTGAATTGTTGTTGGCGCTGACTCTCAATAAAACTGTCGCAATGTAC
CTACTAGGTTCCTCCCGAGGGTTCAGGGACAGCAAGGAGAGCTCCATCCCCCACAGCCCATCTC
CATTCGGGGTCACCTACGTCATCTATGGGTTCTGGTAGTCCTGGGAGAGGCAGGGAAATGTCCT
CGAAAAAGAAAAAAGGGCTGCTCTCCAGAGGCAAGAAACTGCTGCAGAGGCTGGCTGCAGTGAA
GTGACCCCCTGAGCCTCCGGACACTTCCAAATCCATGTCACTCGCTTTAATTCCAAACGAGGAC
TCCCAAAACCCAACCTTGACCCCACCCCACCGCAGCAGTAGAGAGATACACTCTTACACTACCA
TTCACATGACACCACCGGAGAGATCAGGGAAGGGGCTGCACCACGGTCCCCTCCCTCTCTGCTC
CCAAGGTTCTGTCCAAGGTCTGGGGAGGGGGAGAGGGAAGGGCAGCTGGCTGAGCAGCAGGGGT
GGGGGAGGGCTCTCTGCAGCCGCCTCCCCTCCACCTGCAGTTCCAGCCTGCACACACTAGAGGG
CAGGCAGCCCCCGGCAGGACTTCTGACCTCCCCCACTTCTCAAGCGGCTAGCCTCATTACACAT
TACTGTCATTTCCACTCGGCTCTTGAGATTCCTAGTTTAACTCGCCTTGATGTCTGGCCTTATA
AACTGCACAGTGGTTTGTACTGTCAAATAAAAACACCGTGTATACTTCGCATGTGTTGTGCATT
CCTGGTCTTCAACCTCACTGACACAGTGGCTTCACCTCACAGTAGGCCCAGGCCCTACACTTTC
AGCTGCCTGTCTTGGGTCTTTCAAAGCAAGCCAGCAACACACAGGACATGTTTACTAAACCCAC
TACCCAAGAGAGGGGAGTAGGGGGAGAACCGGGCAGCATGCATGTCTTTTAGTCAGCCAGGGAG
CTGACCAATCAATCTTTGCGTTTAGTGTCCTATCCTGTGGCTTTTAGCTTTCTGTTACTTTCAT
TATTTGTTGAAATGCCTTGCCCCGAGATACCATCAAAGCCACCACACATAGCAAAGCCACCACA
CGCTTCATTAGCCAAACCAGAAGGAGCCTAAATTGAAATCTCTCAGACACCCTACACCCATCTT
TCTCATTCGCTTTGAACAGCAGGCCTCCCCAAAATGCTGGCTGACGTACGGTCACGACTTTGTA
ATTCCTGTCCACTGTAAAACTGTTTTTACTCTTTATACATACTTTTCAGACTGCCTTTCTTTTT
GTAATTTCTGGAAGGTTTGTAAATGAATGACGAAGCTTTTCCCCATTGTGTCTTCAAAAACTAT
ATTGTAAATTGTAATATAATTGTATGTGGTAGATTGGATTAAAAGGCCGTTCCTCGGTGTGTGA
AGTGCTGTGCGGATGTGTGCATGTGTACAGTTAGGGTGACATATTTTCTAGAAATAAACTTTGT
TATTTTGTACAATG

hide sequence

RefSeq Acc Id:

XM_039089126 ⟹ XP_038945054

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,436,212 - 33,582,257 (+)	NCBI
mRatBN7.2	12	27,800,195 - 27,946,256 (+)	NCBI

RefSeq Acc Id:

XM_039089127 ⟹ XP_038945055

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,383,648 - 33,582,257 (+)	NCBI
mRatBN7.2	12	27,747,615 - 27,946,256 (+)	NCBI

RefSeq Acc Id:

XM_039089128 ⟹ XP_038945056

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,466,167 - 33,582,257 (+)	NCBI
mRatBN7.2	12	27,830,151 - 27,946,256 (+)	NCBI

RefSeq Acc Id:

XM_039089129 ⟹ XP_038945057

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,466,452 - 33,582,257 (+)	NCBI
mRatBN7.2	12	27,830,565 - 27,946,256 (+)	NCBI

RefSeq Acc Id:

XM_063271094 ⟹ XP_063127164

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,468,402 - 33,582,257 (+)	NCBI

RefSeq Acc Id:

XM_063271095 ⟹ XP_063127165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,383,646 - 33,582,257 (+)	NCBI

RefSeq Acc Id:

XM_063271096 ⟹ XP_063127166

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,383,646 - 33,582,257 (+)	NCBI

RefSeq Acc Id:

XM_063271097 ⟹ XP_063127167

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,383,655 - 33,582,257 (+)	NCBI

RefSeq Acc Id:

XM_063271098 ⟹ XP_063127168

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,466,457 - 33,582,257 (+)	NCBI

RefSeq Acc Id:

XM_063271099 ⟹ XP_063127169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,383,654 - 33,582,257 (+)	NCBI

RefSeq Acc Id:

XM_063271100 ⟹ XP_063127170

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,383,654 - 33,582,257 (+)	NCBI

RefSeq Acc Id:

XM_063271102 ⟹ XP_063127172

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	33,436,224 - 33,582,257 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001093958	(Get FASTA)	NCBI Sequence Viewer
	XP_038945054	(Get FASTA)	NCBI Sequence Viewer
	XP_038945055	(Get FASTA)	NCBI Sequence Viewer
	XP_038945056	(Get FASTA)	NCBI Sequence Viewer
	XP_038945057	(Get FASTA)	NCBI Sequence Viewer
	XP_063127164	(Get FASTA)	NCBI Sequence Viewer
	XP_063127165	(Get FASTA)	NCBI Sequence Viewer
	XP_063127166	(Get FASTA)	NCBI Sequence Viewer
	XP_063127167	(Get FASTA)	NCBI Sequence Viewer
	XP_063127168	(Get FASTA)	NCBI Sequence Viewer
	XP_063127169	(Get FASTA)	NCBI Sequence Viewer
	XP_063127170	(Get FASTA)	NCBI Sequence Viewer
	XP_063127172	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF81658	(Get FASTA)	NCBI Sequence Viewer
	EDM13519	(Get FASTA)	NCBI Sequence Viewer
	EDM13520	(Get FASTA)	NCBI Sequence Viewer
	EDM13521	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000030915
	ENSRNOP00000059643
	ENSRNOP00000073070
	ENSRNOP00000080836
	ENSRNOP00000087009
	ENSRNOP00000111280
GenBank Protein	Q9JIR1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001093958 ⟸ NM_001100488

- UniProtKB:

A0A8I5ZR68 (UniProtKB/TrEMBL), A0A8I6A6H1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MREAAERRQQLELEHEQALAILNAKQQEIQLLQQAQVEAKKEHEGAVQLLENTLDCMQSKVREL
EEKCRVQSEQFNLLSRDLEKFRQHAGSIDLLGSNSVALLDVPLAPGKPFSQYMNGLATSIHKGH
EGPTGHYSVIGDYIPLSGDKLESPCVKPSFLLRSSSPRCRFESEMDDDRSSNKSKHSSSGKVHL
CVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFIQDN
ESRFAGTLGSEQDQNFLNHSGISLERDSILHLHSPTQVDSGITDNGGGTLDVNIDDIGEDIVPY
PRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACT
YRISVQCVTSRGNSDELQCTLLVGKDVVVAPSQLRVDNITQISAQLSWLPTNSNYSHIIFLNEE
ELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQREKKEACVEFSTLPAGPPAPPQ
DVTVQAGATTASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVAEVIAPTADGAAVELVRLR
SLEAKAVSVRTLSAQGESMDSALAAIPPDLLVPPAPHPRTAPPPKPLASDMDTKDLGPHVKVDE
SWEQSRPPGPAHGHMLEPPDMHSTGPGRRSPSPSRILPQPQGAPVSTTVAKAMAREAAQRVAES
NRLEKRSLFLEQSSAGPYANSDEEDGYASPEVKRRGTSVDDFLKGSELGQQPHCCHGDEYHTES
SRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNSALMGRGDRMEHVSRRYSHS
GGGPQRHRPMAPSIDEYTGRDHLSPDFYDESETDPGAEELPARIFVALFDYDPLTMSPNPDAAE
EELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIHADDEEMMDQLLRQGFLPLNTP
VEKIERSRRSGRGHSVPTRRMVALYDYDPRESSPNVDVEAELLFCTGDIITVFGEIDEDGFYYG
ELNGQKGLVPSNFLEEVPDDVEVHLSDAPPHYSHDPPMRTKAKRKKSVHFTP

hide sequence

Ensembl Acc Id:

ENSRNOP00000059643 ⟸ ENSRNOT00000067867

Ensembl Acc Id:

ENSRNOP00000030915 ⟸ ENSRNOT00000033379

Ensembl Acc Id:

ENSRNOP00000073070 ⟸ ENSRNOT00000086078

RefSeq Acc Id:	XP_038945055 ⟸ XM_039089127
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K4J8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038945054 ⟸ XM_039089126
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K4J8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038945056 ⟸ XM_039089128
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K4J8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038945057 ⟸ XM_039089129
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K4J8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000087009 ⟸ ENSRNOT00000115151

Ensembl Acc Id:

ENSRNOP00000080836 ⟸ ENSRNOT00000100361

Ensembl Acc Id:

ENSRNOP00000097882 ⟸ ENSRNOT00000107331

RefSeq Acc Id:	XP_063127165 ⟸ XM_063271095
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K4J8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127166 ⟸ XM_063271096
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2K4J8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127169 ⟸ XM_063271099
- Peptide Label:	isoform X5
- UniProtKB:	A6J0T2 (UniProtKB/TrEMBL), A0A8I6A6H1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127170 ⟸ XM_063271100
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6A6H1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127167 ⟸ XM_063271097
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6A6H1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127172 ⟸ XM_063271102
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6A6H1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127168 ⟸ XM_063271098
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6A6H1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063127164 ⟸ XM_063271094
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K4J8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000111280 ⟸ ENSRNOT00000158624

Protein Domains

Fibronectin type-III SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JIR1-F1-model_v2	AlphaFold	Q9JIR1	1-1049	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708533	AgrOrtholog
BioCyc Gene	G2FUF-19467	BioCyc
Ensembl Genes	ENSRNOG00000022893	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000033379	ENTREZGENE
	ENSRNOT00000067867	ENTREZGENE
	ENSRNOT00000086078	ENTREZGENE
	ENSRNOT00000100361	ENTREZGENE
	ENSRNOT00000115151	ENTREZGENE
	ENSRNOT00000158624	ENTREZGENE
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
	SH3 Domains	UniProtKB/Swiss-Prot
InterPro	FN3_dom	UniProtKB/Swiss-Prot
	FN3_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	RIM-BP_SH3_2	UniProtKB/Swiss-Prot
	RIM-BP_SH3_3	UniProtKB/Swiss-Prot
	RIMBP1/2/3	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
NCBI Gene	266780	ENTREZGENE
PANTHER	PTHR14234	UniProtKB/Swiss-Prot
	PTHR14234:SF18	UniProtKB/Swiss-Prot
Pfam	fn3	UniProtKB/Swiss-Prot
	SH3_2	UniProtKB/Swiss-Prot
	SH3_9	UniProtKB/Swiss-Prot
PhenoGen	Rimbp2	PhenoGen
PRINTS	SH3DOMAIN	UniProtKB/Swiss-Prot
PROSITE	FN3	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000022893	RatGTEx
SMART	FN3	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF49265	UniProtKB/Swiss-Prot
	SSF50044	UniProtKB/Swiss-Prot
UniProt	A0A0G2K4J8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZR68	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A6H1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AV27_RAT	UniProtKB/TrEMBL
	A0ABK0M469_RAT	UniProtKB/TrEMBL
	A6J0T0_RAT	UniProtKB/TrEMBL
	A6J0T2	ENTREZGENE, UniProtKB/TrEMBL
	D4A2L1_RAT	UniProtKB/TrEMBL
	F1LSC8_RAT	UniProtKB/TrEMBL
	Q9JIR1	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-05-05	Rimbp2	RIMS binding protein 2	Rimbp2	RIM binding protein 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-08	Rimbp2	RIM binding protein 2	LOC266780		Symbol updated	1299863	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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