Rps19 (ribosomal protein S19) - Rat Genome Database

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Gene: Rps19 (ribosomal protein S19) Rattus norvegicus
Analyze
Symbol: Rps19
Name: ribosomal protein S19
RGD ID: 68440
Description: Enables translation initiation factor binding activity. A structural constituent of ribosome. Predicted to be involved in several processes, including monocyte chemotaxis; regulation of respiratory burst involved in inflammatory response; and ribosomal small subunit biogenesis. Predicted to act upstream of or within Notch signaling pathway. Located in nucleolus. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia and Diamond-Blackfan anemia 1. Orthologous to human RPS19 (ribosomal protein S19); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 40S ribosomal protein S19; ribosomal protein S19-like2; Rps19l2; small ribosomal subunit protein eS19
RGD Orthologs
Human
Mouse
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rps19-ps18   Rps19l1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,608,408 - 89,614,390 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7104,324,520 - 104,325,132 (-)EnsemblGRCr8
GRCr8 Ensembl189,609,216 - 89,614,386 (+)EnsemblGRCr8
mRatBN7.2180,480,718 - 80,486,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7102,435,666 - 102,436,278 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl180,480,951 - 80,486,508 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx185,873,345 - 85,879,047 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,424,173 - 94,429,875 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,629,105 - 87,634,807 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,802,280 - 16,807,982 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,750,928 - 81,756,627 (+)Ensemblrn6Rnor6.0
Rnor_5.0183,007,889 - 83,013,590 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4180,176,649 - 80,182,351 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera174,928,360 - 74,934,062 (+)NCBICelera
RGSC_v3.1180,254,777 - 80,260,460 (+)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-nitrofluorene  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (ISO)
aflatoxin B1  (EXP)
alpha-Zearalanol  (EXP)
amiodarone  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bortezomib  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
dichlorine  (EXP)
diethylstilbestrol  (EXP,ISO)
dihydroartemisinin  (ISO)
doxorubicin  (ISO)
enzalutamide  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenbuconazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
furan  (EXP)
furfural  (ISO)
genistein  (EXP,ISO)
gentamycin  (EXP)
glafenine  (EXP)
ivermectin  (ISO)
L-ethionine  (EXP)
lead diacetate  (ISO)
melatonin  (ISO)
Mesaconitine  (EXP)
methapyrilene  (EXP,ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-nitrosodimethylamine  (EXP)
nimesulide  (EXP)
nitrates  (ISO)
nitrofen  (EXP)
omeprazole  (EXP)
ozone  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
PhIP  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. Identification of proteins of the 40 S ribosomal subunit involved in interaction with initiation factor eIF-2 in the quaternary initiation complex by means of monospecific antibodies. Bommer UA, etal., FEBS Lett. 1988 Jun 6;233(1):114-8.
3. Nonsense-mediated and nonstop decay of ribosomal protein S19 mRNA in Diamond-Blackfan anemia. Chatr-Aryamontri A, etal., Hum Mutat. 2004 Dec;24(6):526-33.
4. Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 40 S ribosomal subunit proteins Sa, Sc, S3a, S3b, S5', S9, S10, S11, S12, S14, S15, S15', S16, S17, S18, S19, S20, S21, S26, S27', and S29. Collatz E, etal., J Biol Chem. 1977 Dec 25;252(24):9071-80.
5. The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia. Draptchinskaia N, etal., Nat Genet. 1999 Feb;21(2):169-75.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. An overview of pre-ribosomal RNA processing in eukaryotes. Henras AK, etal., Wiley Interdiscip Rev RNA. 2015 Mar-Apr;6(2):225-42. doi: 10.1002/wrna.1269. Epub 2014 Oct 27.
9. Immunoelectron microscopic studies on the location of ribosomal proteins on the surface of the 40S ribosomal subunit from rat liver. Lutsch G, etal., Eur J Cell Biol. 1990 Feb;51(1):140-50.
10. A novel nucleolar protein interacts with ribosomal protein S19. Maeda N, etal., Biochem Biophys Res Commun. 2006 Jan 6;339(1):41-6. Epub 2005 Nov 8.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. GOA pipeline RGD automated data pipeline
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Comprehensive gene review and curation RGD comprehensive gene curation
19. Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing. Sloan KE, etal., J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.
20. The primary structure of rat ribosomal protein S19. Suzuki K, etal., Biochimie 1990 Apr;72(4):299-302.
21. Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. Yu Y, etal., Protein Sci. 2005 Jun;14(6):1438-46. Epub 2005 May 9.
Additional References at PubMed
PMID:8706699   PMID:11226885   PMID:11716516   PMID:12477932   PMID:12586610   PMID:15019208   PMID:15489334   PMID:15750715   PMID:16266891   PMID:16452087   PMID:16990592   PMID:17053056  
PMID:17517689   PMID:18697920   PMID:19155217   PMID:19946888   PMID:20458337   PMID:21423176   PMID:21700703   PMID:22681889   PMID:23376485   PMID:23979707   PMID:25446530   PMID:29476059  
PMID:35352799  


Genomics

Comparative Map Data
Rps19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,608,408 - 89,614,390 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7104,324,520 - 104,325,132 (-)EnsemblGRCr8
GRCr8 Ensembl189,609,216 - 89,614,386 (+)EnsemblGRCr8
mRatBN7.2180,480,718 - 80,486,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7102,435,666 - 102,436,278 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl180,480,951 - 80,486,508 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx185,873,345 - 85,879,047 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,424,173 - 94,429,875 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,629,105 - 87,634,807 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,802,280 - 16,807,982 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,750,928 - 81,756,627 (+)Ensemblrn6Rnor6.0
Rnor_5.0183,007,889 - 83,013,590 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4180,176,649 - 80,182,351 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera174,928,360 - 74,934,062 (+)NCBICelera
RGSC_v3.1180,254,777 - 80,260,460 (+)NCBI
Cytogenetic Map1q21NCBI
RPS19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,860,255 - 41,872,925 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1941,860,255 - 41,872,925 (+)Ensemblhg38GRCh38
GRCh371942,364,325 - 42,376,993 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,055,828 - 47,067,324 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341947,055,827 - 47,067,322NCBI
Celera1939,163,675 - 39,175,171 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1938,795,270 - 38,806,767 (+)NCBIHuRef
CHM1_11942,365,453 - 42,376,951 (+)NCBICHM1_1
T2T-CHM13v2.01944,679,738 - 44,692,405 (+)NCBIT2T-CHM13v2.0
Rps19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,584,013 - 24,589,236 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,583,796 - 24,589,231 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38724,884,592 - 24,889,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl724,884,371 - 24,889,806 (+)Ensemblmm10GRCm38
MGSCv37725,669,733 - 25,674,821 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36724,593,474 - 24,598,562 (+)NCBIMGSCv36mm8
Celera719,500,610 - 19,505,697 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.41NCBI
RPS19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl650,000,948 - 50,010,341 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1650,003,198 - 50,010,135 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2646,056,524 - 46,063,482 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPS19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,067,959 - 36,085,581 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607314,302,605 - 14,313,949 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907810,984 - 818,614 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624907811,069 - 818,218 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rps19
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12169,813,854 - 169,819,479 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rps19
42 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:278
Count of miRNA genes:107
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000027246, ENSRNOT00000073160
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15190920691302615Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
18 13 90 196 109 111 77 95 77 6 423 219 11 175 101 116 34 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027246   ⟹   ENSRNOP00000027246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl189,609,216 - 89,614,386 (+)Ensembl
mRatBN7.2 Ensembl180,480,951 - 80,486,507 (+)Ensembl
Rnor_6.0 Ensembl181,750,928 - 81,756,627 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000041802   ⟹   ENSRNOP00000039845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7104,324,520 - 104,325,132 (-)Ensembl
mRatBN7.2 Ensembl7102,435,666 - 102,436,278 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100988   ⟹   ENSRNOP00000091536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl180,481,102 - 80,486,254 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113827   ⟹   ENSRNOP00000095730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl180,481,102 - 80,486,508 (+)Ensembl
RefSeq Acc Id: NM_001037346   ⟹   NP_001032423
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,608,688 - 89,614,390 (+)NCBI
mRatBN7.2180,480,809 - 80,486,511 (+)NCBI
Rnor_6.0916,802,280 - 16,807,982 (-)NCBI
Rnor_5.0183,007,889 - 83,013,590 (+)NCBI
RGSC_v3.4180,176,649 - 80,182,351 (+)RGD
Celera174,928,360 - 74,934,062 (+)RGD
Sequence:
RefSeq Acc Id: XM_006228411   ⟹   XP_006228473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,608,694 - 89,614,390 (+)NCBI
mRatBN7.2180,480,860 - 80,486,511 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063283883   ⟹   XP_063139953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,608,408 - 89,614,390 (+)NCBI
RefSeq Acc Id: XM_063283886   ⟹   XP_063139956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,608,771 - 89,614,390 (+)NCBI
RefSeq Acc Id: XM_063283888   ⟹   XP_063139958
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,608,720 - 89,614,390 (+)NCBI
RefSeq Acc Id: XM_063283889   ⟹   XP_063139959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,608,408 - 89,613,263 (+)NCBI
RefSeq Acc Id: XM_063283893   ⟹   XP_063139963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8189,608,737 - 89,614,390 (+)NCBI
RefSeq Acc Id: NP_001032423   ⟸   NM_001037346
- UniProtKB: P17074 (UniProtKB/Swiss-Prot),   A6J917 (UniProtKB/TrEMBL),   F1LYF3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027246   ⟸   ENSRNOT00000027246
RefSeq Acc Id: XP_006228473   ⟸   XM_006228411
- Peptide Label: isoform X3
- UniProtKB: P17074 (UniProtKB/Swiss-Prot),   A6J917 (UniProtKB/TrEMBL),   F1LYF3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000095730   ⟸   ENSRNOT00000113827
Ensembl Acc Id: ENSRNOP00000091536   ⟸   ENSRNOT00000100988
RefSeq Acc Id: XP_063139953   ⟸   XM_063283883
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AFS6 (UniProtKB/TrEMBL),   A6J919 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139959   ⟸   XM_063283889
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GLA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139958   ⟸   XM_063283888
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AFS6 (UniProtKB/TrEMBL),   A6J919 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139963   ⟸   XM_063283893
- Peptide Label: isoform X3
- UniProtKB: P17074 (UniProtKB/Swiss-Prot),   F1LYF3 (UniProtKB/TrEMBL),   A6J917 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139956   ⟸   XM_063283886
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AFS6 (UniProtKB/TrEMBL),   A6J919 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000039845   ⟸   ENSRNOT00000041802

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17074-F1-model_v2 AlphaFold P17074 1-145 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696524
Promoter ID:EPDNEW_R7043
Type:multiple initiation site
Name:Rps19_1
Description:ribosomal protein S19
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0916,807,965 - 16,808,025EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68440 AgrOrtholog
BioCyc Gene G2FUF-60412 BioCyc
Ensembl Genes ENSRNOG00000031474 Ensembl
  ENSRNOG00000037897 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000027246 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7308408 IMAGE-MGC_LOAD
InterPro Ribosomal_S19e UniProtKB/Swiss-Prot
  Ribosomal_S19e_CS UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:29287 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105801 IMAGE-MGC_LOAD
NCBI Gene 29287 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S19 UniProtKB/Swiss-Prot
  PTHR11710 UniProtKB/Swiss-Prot
Pfam Ribosomal_S19e UniProtKB/Swiss-Prot
PhenoGen Rps19 PhenoGen
PROSITE RIBOSOMAL_S19E UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031474 RatGTEx
  ENSRNOG00000037897 RatGTEx
SMART Ribosomal_S19e UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot
UniProt A0A8I6AFS6 ENTREZGENE
  A0A8I6GLA3 ENTREZGENE
  A0A8L2QEH3_RAT UniProtKB/TrEMBL
  A6J917 ENTREZGENE, UniProtKB/TrEMBL
  A6J919 ENTREZGENE, UniProtKB/TrEMBL
  F1LYF3 ENTREZGENE, UniProtKB/TrEMBL
  P17074 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-10-01 Rps19  ribosomal protein S19  Rps19l2  ribosomal protein S19-like2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2018-05-04 Rps19l2  ribosomal protein S19-like2  Rps19  ribosomal protein S19  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Rps19  ribosomal protein S19      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_other 15-18 copies of the gene 68299
gene_protein 144 amino acids 68299