Ppp1r9a (protein phosphatase 1, regulatory subunit 9A) - Rat Genome Database

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Gene: Ppp1r9a (protein phosphatase 1, regulatory subunit 9A) Rattus norvegicus
Analyze
Symbol: Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
RGD ID: 632280
Description: Enables several functions, including actin filament binding activity; enzyme binding activity; and transmembrane transporter binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of actin filament organization; and regulation of synapse organization. Acts upstream of or within neuron projection development. Located in several cellular components, including dendritic spine neck; growth cone lamellipodium; and neuromuscular junction. Is active in glutamatergic synapse and postsynaptic actin cytoskeleton. Used to study transient cerebral ischemia. Biomarker of hepatocellular carcinoma. Orthologous to human PPP1R9A (protein phosphatase 1 regulatory subunit 9A); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actin-binding protein neurabin; Neb1; neurabin 1; neurabin-1; neurabin-I; neural tissue-specific F-actin-binding protein I; p180; PP1bp175; protein phosphatase 1 regulatory subunit 9A; protein phosphatase 1, regulatory (inhibitor) subunit 9A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8433,936,949 - 34,258,927 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl433,988,827 - 34,258,927 (+)EnsemblGRCr8
mRatBN7.2432,970,501 - 33,292,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl433,024,450 - 33,286,907 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx437,980,927 - 38,251,396 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0433,907,063 - 34,177,535 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0432,317,198 - 32,587,313 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0429,976,485 - 30,247,371 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl429,978,739 - 30,241,911 (+)Ensemblrn6Rnor6.0
Rnor_5.0429,856,082 - 30,154,334 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4429,654,468 - 29,928,476 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera428,548,989 - 28,813,836 (+)NCBICelera
RGSC_v3.1429,695,157 - 29,966,996 (+)NCBI
Cytogenetic Map4q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-(hydroxymethyl)cytosine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
Adenosine, cyclic 3',5'-[hydrogen [p(s)]-phosphorothioate]  (EXP)
Aflatoxin B2 alpha  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
cisplatin  (ISO)
clotrimazole  (EXP)
cobalt dichloride  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
hydralazine  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
latrunculin B  (EXP)
menadione  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenyl acetate  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
temozolomide  (ISO)
testosterone enanthate  (ISO)
thapsigargin  (EXP)
thiram  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (EXP,ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis. Becanovic K, etal., Hum Mol Genet. 2010 Apr 15;19(8):1438-52. doi: 10.1093/hmg/ddq018. Epub 2010 Jan 20.
2. Dopamine depletion alters phosphorylation of striatal proteins in a model of Parkinsonism. Brown AM, etal., Eur J Neurosci. 2005 Jul;22(1):247-56.
3. Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton. Burnett PE, etal., Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8351-6.
4. Selective targeting of the gamma1 isoform of protein phosphatase 1 to F-actin in intact cells requires multiple domains in spinophilin and neurabin. Carmody LC, etal., FASEB J. 2008 Jun;22(6):1660-71. doi: 10.1096/fj.07-092841. Epub 2008 Jan 23.
5. Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine. Chen Y, etal., J Neurosci. 2012 Feb 22;32(8):2683-95. doi: 10.1523/JNEUROSCI.4125-11.2011.
6. Association of brain protein phosphatase 1 with cytoskeletal targeting/regulatory subunits. Colbran RJ, etal., J Neurochem. 1997 Sep;69(3):920-9.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase. Goel M, etal., Pflugers Arch. 2005 Oct;451(1):87-98. Epub 2005 Jul 16.
9. Actin-associated neurabin-protein phosphatase-1 complex regulates hippocampal plasticity. Hu XD, etal., J Neurochem. 2006 Sep;98(6):1841-51. Epub 2006 Aug 8.
10. Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis. Kakehashi A, etal., Toxicol Sci. 2011 Jan;119(1):61-72. doi: 10.1093/toxsci/kfq307. Epub 2010 Oct 8.
11. Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation. McAvoy T, etal., Biochemistry. 1999 Sep 28;38(39):12943-9.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formation. Nakanishi H, etal., J Cell Biol 1997 Nov 17;139(4):951-61.
14. Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology. Oliver CJ, etal., Mol Cell Biol 2002 Jul;22(13):4690-701.
15. Rac3-induced neuritogenesis requires binding to Neurabin I. Orioli D, etal., Mol Biol Cell. 2006 May;17(5):2391-400. Epub 2006 Mar 8.
16. Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites. Ragusa MJ, etal., Nat Struct Mol Biol. 2010 Apr;17(4):459-64. doi: 10.1038/nsmb.1786. Epub 2010 Mar 21.
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke. Ruscher K, etal., Brain. 2011 Mar;134(Pt 3):732-46. doi: 10.1093/brain/awq367. Epub 2011 Jan 28.
21. Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites. Satoh A, etal., J Biol Chem 1998 Feb 6;273(6):3470-5.
22. Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin. Stephens DJ and Banting G, J Biol Chem. 1999 Oct 15;274(42):30080-6.
23. The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits. Terry-Lorenzo RT, etal., J Biol Chem 2002 Aug 2;277(31):27716-24.
24. Neurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeleton. Terry-Lorenzo RT, etal., J Biol Chem 2002 Nov 29;277(48):46535-43. Epub 2002 Sep 21.
25. Combined comparative and chemical proteomics on the mechanisms of levo-tetrahydropalmatine-induced antinociception in the formalin test. Wang C, etal., J Proteome Res. 2010 Jun 4;9(6):3225-34. doi: 10.1021/pr1001274.
26. Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton. Zito K, etal., Neuron. 2004 Oct 14;44(2):321-34.
Additional References at PubMed
PMID:10585469   PMID:15016827   PMID:15996550   PMID:16600521   PMID:17460080   PMID:17464283   PMID:17600833   PMID:17699587   PMID:20124353   PMID:21094159   PMID:24625528   PMID:29383693  
PMID:29476059  


Genomics

Comparative Map Data
Ppp1r9a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8433,936,949 - 34,258,927 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl433,988,827 - 34,258,927 (+)EnsemblGRCr8
mRatBN7.2432,970,501 - 33,292,360 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl433,024,450 - 33,286,907 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx437,980,927 - 38,251,396 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0433,907,063 - 34,177,535 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0432,317,198 - 32,587,313 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0429,976,485 - 30,247,371 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl429,978,739 - 30,241,911 (+)Ensemblrn6Rnor6.0
Rnor_5.0429,856,082 - 30,154,334 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4429,654,468 - 29,928,476 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera428,548,989 - 28,813,836 (+)NCBICelera
RGSC_v3.1429,695,157 - 29,966,996 (+)NCBI
Cytogenetic Map4q21NCBI
PPP1R9A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38794,907,236 - 95,296,415 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl794,907,202 - 95,296,415 (+)Ensemblhg38GRCh38
GRCh37794,536,906 - 94,925,727 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36794,374,885 - 94,763,663 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34794,185,142 - 94,567,392NCBI
Celera789,235,114 - 89,624,424 (+)NCBICelera
Cytogenetic Map7q21.3NCBI
HuRef789,144,178 - 89,532,759 (+)NCBIHuRef
CHM1_1794,466,972 - 94,855,738 (+)NCBICHM1_1
T2T-CHM13v2.0796,143,048 - 96,532,571 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2793,865,965 - 94,254,723 (+)NCBI
Ppp1r9a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3964,902,702 - 5,165,661 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl64,902,917 - 5,165,661 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3864,902,872 - 5,165,661 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl64,902,917 - 5,165,661 (+)Ensemblmm10GRCm38
MGSCv3764,853,320 - 5,115,661 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3664,853,320 - 5,115,661 (+)NCBIMGSCv36mm8
Celera65,049,683 - 5,311,917 (+)NCBICelera
Cytogenetic Map6A1NCBI
cM Map61.86NCBI
Ppp1r9a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543211,608,382 - 11,886,044 (+)Ensembl
ChiLan1.0NW_00495543211,607,269 - 11,891,568 (+)NCBIChiLan1.0ChiLan1.0
PPP1R9A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26112,751,561 - 113,136,320 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17161,016,200 - 161,400,959 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0786,863,919 - 87,251,634 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17100,453,090 - 100,839,325 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7100,455,357 - 100,833,220 (+)EnsemblpanPan2panpan1.1
PPP1R9A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11420,251,791 - 20,563,315 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1420,251,738 - 20,557,208 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1419,810,502 - 20,122,327 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01420,073,523 - 20,385,742 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1420,073,561 - 20,383,314 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11420,218,353 - 20,530,386 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01419,953,584 - 20,265,515 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01420,211,007 - 20,522,870 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppp1r9a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511833,585,519 - 33,881,736 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365854,987,529 - 5,277,191 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365854,981,555 - 5,277,185 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R9A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl974,635,403 - 74,940,362 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1974,635,285 - 74,944,050 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2981,987,561 - 82,105,844 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R9A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12153,744,202 - 54,129,709 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2153,747,857 - 54,127,005 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604250,200,716 - 50,591,491 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r9a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248131,588,261 - 1,945,788 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248131,587,567 - 1,951,620 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ppp1r9a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16133,426,611 - 133,593,464 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ppp1r9a
1395 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:53
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000011756
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)41308014658080146Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41564430960644309Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41103870656038706Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4134142783Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4134142783Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41103870656038706Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42228845340471598Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41103870656038706Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41890069763900697Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4145429897Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41103870656038706Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42228845363245191Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)41890069763900697Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41103870656038706Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4140471598Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4588999950889999Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41891315163913151Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42786220462997402Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42192515166925151Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41103870656038706Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43353881653719714Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42228845345429897Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41075870140490708Rat

Markers in Region
D4Got286  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2433,044,357 - 33,044,568 (+)MAPPERmRatBN7.2
Rnor_6.0429,998,647 - 29,998,857NCBIRnor6.0
Rnor_5.0429,904,944 - 29,905,154UniSTSRnor5.0
RGSC_v3.4429,676,774 - 29,676,984UniSTSRGSC3.4
Celera428,571,044 - 28,571,254UniSTS
Cytogenetic Map4q13UniSTS
RH143674  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2433,128,541 - 33,128,665 (+)MAPPERmRatBN7.2
Rnor_6.0430,082,664 - 30,082,787NCBIRnor6.0
Rnor_5.0429,988,963 - 29,989,086UniSTSRnor5.0
RGSC_v3.4429,764,016 - 29,764,139UniSTSRGSC3.4
Celera428,655,245 - 28,655,368UniSTS
Cytogenetic Map4q13UniSTS
BF393278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2433,279,761 - 33,280,001 (+)MAPPERmRatBN7.2
Rnor_6.0430,234,766 - 30,235,005NCBIRnor6.0
Rnor_5.0430,141,729 - 30,141,968UniSTSRnor5.0
RGSC_v3.4429,921,314 - 29,921,553UniSTSRGSC3.4
Celera428,806,691 - 28,806,930UniSTS
RH 3.4 Map4218.84UniSTS
Cytogenetic Map4q13UniSTS
AW530668  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2433,260,061 - 33,260,212 (+)MAPPERmRatBN7.2
Rnor_6.0430,215,066 - 30,215,216NCBIRnor6.0
Rnor_5.0430,122,029 - 30,122,179UniSTSRnor5.0
RGSC_v3.4429,901,614 - 29,901,764UniSTSRGSC3.4
Celera428,786,991 - 28,787,141UniSTS
RH 3.4 Map4218.44UniSTS
Cytogenetic Map4q13UniSTS
U66888  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2433,162,835 - 33,163,499 (+)MAPPERmRatBN7.2
Rnor_6.0430,117,906 - 30,118,569NCBIRnor6.0
Rnor_5.0430,024,205 - 30,024,868UniSTSRnor5.0
RGSC_v3.4429,802,996 - 29,803,659UniSTSRGSC3.4
Celera428,689,537 - 28,690,200UniSTS
Cytogenetic Map4q13UniSTS
UniSTS:532171  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2433,204,705 - 33,204,819 (+)MAPPERmRatBN7.2
Rnor_6.0430,159,776 - 30,159,889NCBIRnor6.0
Rnor_5.0430,066,075 - 30,066,188UniSTSRnor5.0
Celera428,731,458 - 28,731,571UniSTS
Cytogenetic Map4q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 90 89 58 52 58 6 315 152 10 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001401497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005503322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011756   ⟹   ENSRNOP00000011756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl433,988,827 - 34,258,927 (+)Ensembl
mRatBN7.2 Ensembl433,024,450 - 33,286,907 (+)Ensembl
Rnor_6.0 Ensembl429,978,739 - 30,241,911 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104466   ⟹   ENSRNOP00000078577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl433,988,827 - 34,258,927 (+)Ensembl
mRatBN7.2 Ensembl433,024,450 - 33,286,907 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121067   ⟹   ENSRNOP00000098610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl433,988,827 - 34,258,927 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121068   ⟹   ENSRNOP00000098611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl433,988,827 - 34,258,927 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121069   ⟹   ENSRNOP00000098612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl433,989,172 - 34,258,927 (+)Ensembl
RefSeq Acc Id: NM_001401497   ⟹   NP_001388426
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,988,827 - 34,258,927 (+)NCBI
mRatBN7.2433,022,254 - 33,292,360 (+)NCBI
RefSeq Acc Id: NM_053473   ⟹   NP_445925
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,988,827 - 34,258,927 (+)NCBI
mRatBN7.2433,022,254 - 33,292,360 (+)NCBI
Rnor_6.0429,976,587 - 30,241,911 (+)NCBI
Rnor_5.0429,856,082 - 30,154,334 (+)NCBI
RGSC_v3.4429,654,468 - 29,928,476 (+)RGD
Celera428,548,989 - 28,813,836 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236058   ⟹   XP_006236120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
mRatBN7.2433,022,546 - 33,292,360 (+)NCBI
Rnor_6.0429,976,836 - 30,247,371 (+)NCBI
Rnor_5.0429,856,082 - 30,154,334 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592928   ⟹   XP_017448417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,579 - 34,258,927 (+)NCBI
mRatBN7.2433,022,800 - 33,292,360 (+)NCBI
Rnor_6.0429,977,350 - 30,247,371 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039108474   ⟹   XP_038964402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,936,949 - 34,258,927 (+)NCBI
mRatBN7.2432,970,501 - 33,292,360 (+)NCBI
RefSeq Acc Id: XM_039108475   ⟹   XP_038964403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
mRatBN7.2433,022,546 - 33,292,360 (+)NCBI
RefSeq Acc Id: XM_039108476   ⟹   XP_038964404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
mRatBN7.2433,022,546 - 33,292,360 (+)NCBI
RefSeq Acc Id: XM_039108477   ⟹   XP_038964405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
mRatBN7.2433,022,546 - 33,292,360 (+)NCBI
RefSeq Acc Id: XM_039108479   ⟹   XP_038964407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
mRatBN7.2433,022,546 - 33,292,360 (+)NCBI
RefSeq Acc Id: XM_039108480   ⟹   XP_038964408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
mRatBN7.2433,022,546 - 33,292,360 (+)NCBI
RefSeq Acc Id: XM_039108481   ⟹   XP_038964409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
mRatBN7.2433,022,546 - 33,292,360 (+)NCBI
RefSeq Acc Id: XM_063286768   ⟹   XP_063142838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,988,683 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286770   ⟹   XP_063142840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,988,683 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286771   ⟹   XP_063142841
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,579 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286772   ⟹   XP_063142842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,988,683 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286773   ⟹   XP_063142843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286774   ⟹   XP_063142844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,579 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286775   ⟹   XP_063142845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,988,683 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286777   ⟹   XP_063142847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,579 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286778   ⟹   XP_063142848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,936,977 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286779   ⟹   XP_063142849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,258,927 (+)NCBI
RefSeq Acc Id: XM_063286780   ⟹   XP_063142850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,988,683 - 34,258,927 (+)NCBI
RefSeq Acc Id: XR_005503322
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8433,989,140 - 34,236,645 (+)NCBI
mRatBN7.2433,022,546 - 33,270,127 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001388426 (Get FASTA)   NCBI Sequence Viewer  
  NP_445925 (Get FASTA)   NCBI Sequence Viewer  
  XP_006236120 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448417 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964402 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964403 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964404 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964405 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964407 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964408 (Get FASTA)   NCBI Sequence Viewer  
  XP_038964409 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142838 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142840 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142841 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142842 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142843 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142844 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142845 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142847 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142848 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142849 (Get FASTA)   NCBI Sequence Viewer  
  XP_063142850 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53454 (Get FASTA)   NCBI Sequence Viewer  
  EDM15014 (Get FASTA)   NCBI Sequence Viewer  
  EDM15015 (Get FASTA)   NCBI Sequence Viewer  
  EDM15016 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011756
  ENSRNOP00000011756.4
  ENSRNOP00000078577
  ENSRNOP00000098611
  ENSRNOP00000098612
GenBank Protein O35867 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445925   ⟸   NM_053473
- Peptide Label: isoform 2
- UniProtKB: O35867 (UniProtKB/Swiss-Prot),   A6IDS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236120   ⟸   XM_006236058
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017448417   ⟸   XM_017592928
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000011756   ⟸   ENSRNOT00000011756
RefSeq Acc Id: XP_038964402   ⟸   XM_039108474
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038964403   ⟸   XM_039108475
- Peptide Label: isoform X2
- UniProtKB: A6IDS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038964407   ⟸   XM_039108479
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038964408   ⟸   XM_039108480
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038964404   ⟸   XM_039108476
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038964405   ⟸   XM_039108477
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038964409   ⟸   XM_039108481
- Peptide Label: isoform X9
- UniProtKB: O35867 (UniProtKB/Swiss-Prot),   A6IDS9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078577   ⟸   ENSRNOT00000104466
RefSeq Acc Id: NP_001388426   ⟸   NM_001401497
- Peptide Label: isoform 1
RefSeq Acc Id: XP_063142848   ⟸   XM_063286778
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063142838   ⟸   XM_063286768
- Peptide Label: isoform X2
- UniProtKB: A6IDS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142845   ⟸   XM_063286775
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063142840   ⟸   XM_063286770
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063142842   ⟸   XM_063286772
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZL80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142850   ⟸   XM_063286780
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063142843   ⟸   XM_063286773
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063142849   ⟸   XM_063286779
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063142841   ⟸   XM_063286771
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063142847   ⟸   XM_063286777
- Peptide Label: isoform X9
- UniProtKB: O35867 (UniProtKB/Swiss-Prot),   A6IDS9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142844   ⟸   XM_063286774
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000098610   ⟸   ENSRNOT00000121067
Ensembl Acc Id: ENSRNOP00000098611   ⟸   ENSRNOT00000121068
Ensembl Acc Id: ENSRNOP00000098612   ⟸   ENSRNOT00000121069
Protein Domains
PDZ   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35867-F1-model_v2 AlphaFold O35867 1-1095 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:632280 AgrOrtholog
BIND 130598
  130599
BioCyc Gene G2FUF-45713 BioCyc
Ensembl Genes ENSRNOG00000008869 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011756 ENTREZGENE
  ENSRNOT00000011756.5 UniProtKB/Swiss-Prot
  ENSRNOT00000104466 ENTREZGENE
  ENSRNOT00000121068 ENTREZGENE
  ENSRNOT00000121069 ENTREZGENE
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  2.30.42.10 UniProtKB/Swiss-Prot
InterPro Neurabin-1/2_PDZ UniProtKB/Swiss-Prot
  Neurabin-like UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
KEGG Report rno:84685 UniProtKB/Swiss-Prot
NCBI Gene 84685 ENTREZGENE
PANTHER PTHR16154 UniProtKB/Swiss-Prot
  PTHR16154:SF22 UniProtKB/Swiss-Prot
Pfam PDZ UniProtKB/Swiss-Prot
  PDZ_5 UniProtKB/Swiss-Prot
  SAM_2 UniProtKB/Swiss-Prot
PhenoGen Ppp1r9a PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot
  SAM_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008869 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
UniProt A0A8I5ZL80 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L3T9_RAT UniProtKB/TrEMBL
  A0ABK0LBG5_RAT UniProtKB/TrEMBL
  A6IDS7 ENTREZGENE, UniProtKB/TrEMBL
  A6IDS9 ENTREZGENE, UniProtKB/TrEMBL
  NEB1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-10-18 Ppp1r9a  protein phosphatase 1, regulatory subunit 9A  Ppp1r9a  protein phosphatase 1, regulatory (inhibitor) subunit 9A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Ppp1r9a  protein phosphatase 1, regulatory (inhibitor) subunit 9A  Ppp1r9a  neurabin 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Ppp1r9a  neurabin 1  Neb1    Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized in the PSD (post-synaptic density) 625568
gene_cellular_localization localized in the PSD (post-synaptic density) 625591
gene_cellular_localization localized in the PSD (post-synaptic density) 625592
gene_domains has one F-actin binding domain at the amino-terminal region, one PSD-95, DlgA, ZO-1-like domain in the middle and a domain which interacts with transmembrane proteins at the COOH-terminus 625568
gene_domains has one F-actin binding domain at the amino-terminal region, one PSD-95, DlgA, ZO-1-like domain in the middle and a domain which interacts with transmembrane proteins at the COOH-terminus 625591
gene_domains has one F-actin binding domain at the amino-terminal region, one PSD-95, DlgA, ZO-1-like domain in the middle and a domain which interacts with transmembrane proteins at the COOH-terminus 625592
gene_expression purified from rat brain neural tissues 625568
gene_expression purified from rat brain neural tissues 625591
gene_expression purified from rat brain neural tissues 625592
gene_function binds to protein phosphatase 1 625568
gene_function binds to protein phosphatase 1 625591
gene_function binds to protein phosphatase 1 625592
gene_function neural tissue-specific F-actin-binding protein 625568
gene_function neural tissue-specific F-actin-binding protein 625591
gene_function neural tissue-specific F-actin-binding protein 625592
gene_function binds to actin filaments 625568
gene_function binds to actin filaments 625591
gene_function binds to actin filaments 625592
gene_physical_interaction interacts with protein phosphatase type 1 alpha and type 1 gamma isoform 1 to regulate synaptic transmission 625568
gene_physical_interaction interacts with protein phosphatase type 1 alpha and type 1 gamma isoform 1 to regulate synaptic transmission 625591
gene_physical_interaction interacts with protein phosphatase type 1 alpha and type 1 gamma isoform 1 to regulate synaptic transmission 625592
gene_physical_interaction binds to protein phosphatase1 625568
gene_physical_interaction binds to protein phosphatase1 625591
gene_physical_interaction binds to protein phosphatase1 625592
gene_process involved in vesicular trafficking in developing and developed neurons and formation and maintenance of synaptic junctions 625568
gene_process involved in vesicular trafficking in developing and developed neurons and formation and maintenance of synaptic junctions 625591
gene_process involved in vesicular trafficking in developing and developed neurons and formation and maintenance of synaptic junctions 625592
gene_process regulates synaptic activity by binding to protein phosphatase type 1 alpha and gamma isoform 1 present in the PSD and can be phosphorylated by PKA 625568
gene_process regulates synaptic activity by binding to protein phosphatase type 1 alpha and gamma isoform 1 present in the PSD and can be phosphorylated by PKA 625591
gene_process regulates synaptic activity by binding to protein phosphatase type 1 alpha and gamma isoform 1 present in the PSD and can be phosphorylated by PKA 625592
gene_process interacts with protein phosphatase type 1 alpha and type 1 gamma isoform 1 to regulate synaptic transmission  
gene_product 180 kD protein 625568
gene_product 180 kD protein 625591
gene_product 180 kD protein 625592
gene_product neural tissue-specific F-actin-binding protein  
gene_protein 180 kD in size 625592