Vim (vimentin) - Rat Genome Database

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Gene: Vim (vimentin) Rattus norvegicus
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Symbol: Vim
Name: vimentin
RGD ID: 621646
Description: Enables protein phosphatase 2A binding activity and protein tyrosine kinase binding activity. Involved in several processes, including decidualization; positive regulation of glial cell proliferation; and response to vitamin D. Located in axon; cell body; and perinuclear region of cytoplasm. Biomarker of Chagas disease; cerebral infarction; hyperthyroidism; nephrosis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in atherosclerosis; autoimmune disease (multiple); and cataract 30. Orthologous to human VIM (vimentin); PARTICIPATES IN cyclooxygenase mediated pathway of arachidonic acid metabolism; INTERACTS WITH (R)-carnitine; (R,R)-tramadol; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81781,577,261 - 81,585,746 (+)NCBIGRCr8
mRatBN7.21776,668,701 - 76,677,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1776,668,647 - 76,677,187 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1780,141,211 - 80,149,708 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01783,976,613 - 83,985,110 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01778,024,506 - 78,033,003 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01780,882,715 - 80,891,200 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1780,882,666 - 80,891,212 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01782,500,898 - 82,509,383 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41787,847,280 - 87,855,763 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11787,858,112 - 87,866,596 (+)NCBI
Celera1776,037,845 - 76,046,329 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis type 1  (ISO)
Animal Disease Models  (ISO)
atherosclerosis  (ISO)
Behcet's disease  (ISO)
Brain Injuries  (IEP,ISO)
Breast Neoplasms  (ISO)
carcinosarcoma  (ISO)
cataract  (ISO)
cataract 30  (ISO,ISS)
cerebral infarction  (IEP)
Chagas disease  (IEP,ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chronic Intermittent Hypoxia  (IEP)
Closed Head Injuries  (IEP)
coronary artery disease  (ISO)
COVID-19  (ISO)
diabetes mellitus  (ISO)
Experimental Arthritis  (IDA)
Experimental Liver Cirrhosis  (IEP,ISO)
Experimental Liver Neoplasms  (IDA)
Fever  (IEP)
Fibrosis  (ISO)
Gliosis  (IEP,IMP)
hyperthyroidism  (IEP)
hypoparathyroidism-deafness-renal disease syndrome  (ISO)
Imerslund-Grasbeck Syndrome  (ISO)
kidney disease  (ISO)
liver cirrhosis  (ISO)
malignant mesothelioma  (ISO)
motor neuron disease  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
nephrosis  (IEP,ISO)
neurodegenerative disease  (ISO)
osteoarthritis  (ISO)
Penetrating Head Injuries  (ISO)
Peritoneal Neoplasms  (ISO)
Prostatic Neoplasms  (ISO)
Pulmonary Arterial Hypertension  (ISO)
pulmonary hypertension  (IEP)
Reperfusion Injury  (ISO)
retinal disease  (ISO)
rheumatoid arthritis  (ISO)
severe acute respiratory syndrome  (ISO)
Sjogren's syndrome  (ISO)
Spinal Cord Injuries  (IEP,ISO)
synovial sarcoma  (ISO)
systemic lupus erythematosus  (ISO)
Urination Disorders  (IMP)
varicose veins  (ISO)
Vascular Remodeling  (IEP)
Weight Gain  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-citrinin  (ISO)
(-)-ephedrine  (ISO)
(1->4)-beta-D-glucan  (ISO)
(20S)-ginsenoside Rg3  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(R)-amygdalin  (ISO)
(R)-carnitine  (EXP)
(R,R)-tramadol  (EXP)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,3-dinitrobenzene  (EXP)
1,4-dithiothreitol  (ISO)
1-naphthyl isothiocyanate  (EXP)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,5-hexanedione  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP,ISO)
2-bromohexadecanoic acid  (ISO)
2-methoxyethanol  (EXP)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (EXP)
2-naphthylamine  (ISO)
2-nitrofluorene  (EXP)
2-Oxohexane  (ISO)
2-palmitoylglycerol  (ISO)
26-hydroxycholesterol  (ISO)
3',5'-cyclic GMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,4-dihydroxybenzaldehyde  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-hydroperoxycyclophosphamide  (ISO)
4-hydroxy-17beta-estradiol  (ISO)
4-hydroxyhexenal  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (EXP,ISO)
5-fluorouracil  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP)
6-Cyano-7-nitroquinoxaline-2,3-dione  (EXP)
6-propyl-2-thiouracil  (EXP,ISO)
7,12-dimethyltetraphene  (ISO)
9-cis-retinoic acid  (ISO)
[6]-Shogaol  (ISO)
Ac-Ser-Asp-Lys-Pro-OH  (ISO)
acetamide  (EXP)
acetylcholine  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
adenine  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (EXP)
allyl isothiocyanate  (ISO)
alpha-naphthoflavone  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
Ammothamnine  (ISO)
amphetamine  (EXP)
andrographolide  (ISO)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimycin A  (ISO)
arecoline  (ISO)
aristolochic acid A  (EXP,ISO)
Aroclor 1254  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
aspartame  (ISO)
atorvastatin calcium  (EXP)
atrazine  (ISO)
azoxystrobin  (ISO)
bacitracin  (EXP)
bafilomycin A1  (ISO)
bathocuproine disulfonic acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP,ISO)
Brodifacoum  (EXP)
bucladesine  (ISO)
buspirone  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
calcitriol  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
calyculin a  (EXP)
cannabidiol  (ISO)
capsaicin  (EXP,ISO)
captan  (ISO)
captopril  (ISO)
carbon nanotube  (ISO)
carboplatin  (EXP)
carboxy-PTIO  (ISO)
carvedilol  (EXP)
casticin  (ISO)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cholesterol  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
chrysin  (ISO)
cisatracurium  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (ISO)
clodronic acid  (EXP)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
coumarin  (ISO)
crizotinib  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
curcumin  (EXP,ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP,ISO)
D-glucose  (ISO)
dantrolene  (EXP)
dapagliflozin  (EXP)
daunorubicin  (EXP)
DDE  (EXP,ISO)
DDT  (ISO)
decabromodiphenyl ether  (EXP)
deguelin  (ISO)
Deoxyschizandrin  (ISO)
Destruxin B  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Di-n-octyl phthalate  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dichromium trioxide  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
Dictamnine  (ISO)
Didecyldimethylammonium  (ISO)
dieckol  (ISO)
diethylstilbestrol  (ISO)
dihydroartemisinin  (ISO)
dimethyl sulfoxide  (ISO)
Diosbulbin B  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
diuron  (EXP,ISO)
dizocilpine maleate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP,ISO)
emodin  (EXP)
endosulfan  (EXP,ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ergosta-4,6,8(14),22-tetraen-3-one  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP)
everolimus  (ISO)
fenamidone  (ISO)
fenpropathrin  (EXP)
fentin chloride  (ISO)
fenvalerate  (EXP)
ferrostatin-1  (ISO)
ferulic acid  (EXP,ISO)
finasteride  (EXP)
fisetin  (ISO)
flavonol  (ISO)
fluvastatin  (EXP)
folic acid  (ISO)
folpet  (ISO)
fructose  (EXP)
fulvestrant  (ISO)
furan  (EXP)
galaxolide  (ISO)
gefitinib  (ISO)
genistein  (ISO)
gentamycin  (EXP)
gingerol  (ISO)
Ginkgoic acid  (ISO)
Glabrene  (ISO)
glabridin  (ISO)
glucose  (ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
goralatide  (ISO)
GW 6471  (EXP)
heptachlor  (ISO)
hexane  (ISO)
homocysteine  (EXP)
hyaluronic acid  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (ISO)
icariside II  (ISO)
indole-3-methanol  (ISO)
indometacin  (EXP,ISO)
ionomycin  (ISO)
isoorientin  (ISO)
isopimaric acid  (ISO)
isoprenaline  (ISO)
isorhamnetin  (ISO)
ivermectin  (ISO)
jaspamide  (ISO)
ketamine  (EXP,ISO)
ketoconazole  (EXP)
KN-93  (EXP)
L-1,4-dithiothreitol  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lapatinib  (ISO)
lead diacetate  (EXP,ISO)
lead(II) chloride  (ISO)
leflunomide  (EXP)
levofloxacin  (EXP)
limonin  (ISO)
linsidomine  (EXP)
lipopolysaccharide  (ISO)
lithium chloride  (EXP,ISO)
loliolide  (ISO)
losartan  (ISO)
lutein  (ISO)
LY294002  (ISO)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylmercury chloride  (EXP,ISO)
methylseleninic acid  (ISO)
microcystin-LR  (EXP,ISO)
mifepristone  (ISO)
MK-2206  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (EXP)
Monobutylphthalate  (ISO)
monocrotaline  (EXP,ISO)
morphine  (EXP)
morusin  (ISO)
N(6)-dimethylallyladenine  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nafenopin  (EXP)
nefazodone  (EXP)
Neferine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel subsulfide  (EXP)
niclosamide  (ISO)
nicotine  (ISO)
nifedipine  (EXP)
nimesulide  (EXP)
nitrogen mustard  (ISO)
Nonylphenol  (EXP,ISO)
nystatin  (ISO)
ochratoxin A  (EXP,ISO)
Ophiopogonin D  (ISO)
oridonin  (ISO)
ouabain  (ISO)
oxcarbazepine  (EXP)
oxycodone  (EXP)
ozone  (EXP,ISO)
Pachymic acid  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parecoxib  (ISO)
patulin  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
phenol red  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
Phytolaccoside E  (ISO)
picoxystrobin  (ISO)
pifithrin-?  (ISO)
pirinixic acid  (ISO)
plerixafor  (ISO)
poly(guanylic acid)  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propiconazole  (EXP,ISO)
propofol  (ISO)
pyrethrins  (EXP)
pyrogallol  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
pyrvinium  (ISO)
quartz  (ISO)
quercetin  (EXP,ISO)
radon atom  (ISO)
radon(0)  (ISO)
Rebamipide  (EXP)
reparixin  (ISO)
resveratrol  (EXP,ISO)
ridaforolimus  (ISO)
rimonabant  (ISO)
rolipram  (ISO)
rosmarinic acid  (EXP)
rotenone  (EXP,ISO)
rottlerin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP,ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
Salinomycin  (ISO)
sanguinarine  (ISO)
SB 203580  (ISO)
SB 290157  (ISO)
SB 431542  (EXP,ISO)
SCH772984  (ISO)
selenium atom  (EXP,ISO)
serpentine asbestos  (ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP,ISO)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium fluoride  (EXP)
sodium hydrogencarbonate  (EXP)
solasodine  (ISO)
Soman  (EXP)
sorafenib  (ISO)
spiromesifen  (ISO)
stattic  (ISO)
staurosporine  (EXP)
streptozocin  (EXP)
sulfasalazine  (ISO)
sulforaphane  (EXP,ISO)
Swertiamarin  (EXP)
tacrolimus hydrate  (ISO)
tamibarotene  (ISO)
Tanshinone I  (ISO)
taraxasterol  (ISO)
teprenone  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetraethylenepentamine  (ISO)
thifluzamide  (ISO)
thioacetamide  (EXP,ISO)
thymoquinone  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
toxaphene  (ISO)
tramadol  (EXP)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (EXP,ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triphenylstannane  (ISO)
triptonide  (ISO)
Tubeimoside II  (ISO)
tyrphostin AG 1478  (ISO)
U-73122  (EXP)
undecane  (EXP)
ursolic acid  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP,ISO)
verapamil  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
warfarin  (ISO)
wortmannin  (ISO)
XAV939  (ISO)
Y-27632  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Antibody to intermediate filaments of the cytoskeleton in patients with Behcet's disease. Akoglu T, etal., Clin Immunol Immunopathol. 1986 Dec;41(3):427-32.
2. Glial fibrillary acidic protein and vimentin expression is regulated by glucocorticoids and neurotrophic factors in primary rat astroglial cultures. Avola R, etal., Clin Exp Hypertens. 2004 May;26(4):323-33.
3. Intermediate filament change in astrocytes following mild cortical contusion. Baldwin SA and Scheff SW, Glia. 1996 Mar;16(3):266-75.
4. Expression and distribution of cytokeratins and vimentin in rat larynx and trachea following irradiation. Bartel-Friedrich S, etal., Anticancer Res. 2007 Jul-Aug;27(4A):2059-69.
5. Induction of Hsp27 and Hsp32 stress proteins and vimentin in glial cells of the rat hippocampus following hyperthermia. Bechtold DA and Brown IR, Neurochem Res 2003 Aug;28(8):1163-73.
6. Alterations of the extracellular matrix of lung during zinc deficiency. Biaggio VS, etal., Br J Nutr. 2011 Oct 12:1-9.
7. Differential expression of vimentin in rat prostatic tumors. Bussemakers MJ, etal., Biochem Biophys Res Commun 1992 Feb 14;182(3):1254-9.
8. Increased expression of retroviral sequences in progressionally advanced rat prostatic tumors. Bussemakers MJ, etal., Biochem Biophys Res Commun 1992 Jan 15;182(1):318-24.
9. Vimentin phosphorylation by Cdc2 in Schwann cell controls axon growth via beta1-integrin activation. Chang IA, etal., FASEB J. 2012 Feb 27.
10. Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study. Chen YM, etal., Biol Reprod. 2003 Aug;69(2):656-72. Epub 2003 Apr 16.
11. Association of protein phosphatase 2A with its substrate vimentin intermediate filaments in 9L rat brain tumor cells. Cheng TJ, etal., J Cell Biochem. 2000 Jul 19;79(1):126-38.
12. Expression of nestin, desmin and vimentin in intact and regenerating muscle spindles of rat hind limb skeletal muscles. Cizkova D, etal., Histochem Cell Biol. 2009 Feb;131(2):197-206. Epub 2008 Oct 22.
13. First evidence of aryl hydrocarbon receptor as a druggable target in hypertension induced by chronic intermittent hypoxia. Coelho NR, etal., Pharmacol Res. 2020 Sep;159:104869. doi: 10.1016/j.phrs.2020.104869. Epub 2020 May 19.
14. [Expression patterns of age-related molecule c-kit, HIWI and vimentin in the rat testis and epididymis]. Duan YG, etal., Zhonghua Nan Ke Xue. 2007 Nov;13(11):992-6.
15. Association of anti-modified citrullinated vimentin with subclinical atherosclerosis in early rheumatoid arthritis compared with anti-cyclic citrullinated peptide. El-Barbary AM, etal., J Rheumatol. 2011 May;38(5):828-34. Epub 2011 Mar 1.
16. The effects of di(2-ethylhexyl)phthalate exposure and selenium nutrition on sertoli cell vimentin structure and germ-cell apoptosis in rat testis. Erkekoglu P, etal., Arch Environ Contam Toxicol. 2012 Apr;62(3):539-47. Epub 2011 Oct 16.
17. Anticytoskeletal autoantibody development in adjuvant arthritis. Franch A, etal., J Rheumatol. 1994 Mar;21(3):489-97.
18. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
19. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
20. 14-3-3 beta in the healthy and diseased male reproductive system. Graf M, etal., Hum Reprod. 2011 Jan;26(1):59-66. doi: 10.1093/humrep/deq319. Epub 2010 Nov 26.
21. Effect of miR-182 on hepatic fibrosis induced by Schistosomiasis japonica by targeting FOXO1 through PI3K/AKT signaling pathway. Huang Y, etal., J Cell Physiol. 2018 Oct;233(10):6693-6704. doi: 10.1002/jcp.26469. Epub 2018 Apr 25.
22. Upregulated vimentin suggests new areas of neurodegeneration in a model of an alcohol use disorder. Kelso ML, etal., Neuroscience. 2011 Dec 1;197:381-93. Epub 2011 Sep 16.
23. Distribution of laminin, vimentin and desmin in the rat uterus during initial stages of implantation. Korgun ET, etal., J Mol Histol. 2007 Aug;38(4):253-60. Epub 2007 May 22.
24. Vimentin-immunopositive cells in the rat telencephalon after experimental ischemic stroke. Korzhevskii DE, etal., Neurosci Behav Physiol. 2008 Oct;38(8):845-8. Epub 2008 Sep 18.
25. Antibodies to cytoplasmic intermediate filaments in rheumatic diseases. Kurki P, etal., J Rheumatol. 1983 Aug;10(4):558-62.
26. Rab8B GTPase and junction dynamics in the testis. Lau AS and Mruk DD, Endocrinology. 2003 Apr;144(4):1549-63.
27. Neuronal expression of vimentin in the Alzheimer's disease brain may be part of a generalized dendritic damage-response mechanism. Levin EC, etal., Brain Res. 2009 Nov 17;1298:194-207. Epub 2009 Sep 1.
28. Ginkgolic acid (GA) suppresses gastric cancer growth by inducing apoptosis and suppressing STAT3/JAK2 signaling regulated by ROS. Liang JR and Yang H, Biomed Pharmacother. 2020 May;125:109585. doi: 10.1016/j.biopha.2019.109585. Epub 2020 Feb 25.
29. Effect of vimentin on reactive gliosis: in vitro and in vivo analysis. Lin J and Cai W, J Neurotrauma. 2004 Nov;21(11):1671-82.
30. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
31. Temporal patterns of the embryonic intermediate filaments nestin and vimentin expression in the cerebral cortex of adult rats after cryoinjury. Moon C, etal., Brain Res. 2004 Dec 3;1028(2):238-42.
32. Actin and Vimentin proteins with N-terminal deletion detected in tumor-bearing rat livers induced by intraportal-vein injection of Ha-ras-transfected rat liver cells. Nakamura Y, etal., Int J Cancer. 2009 Jun 1;124(11):2512-9.
33. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
34. Molecules in focus: cytosolic phospholipase A2-alpha. Niknami M, etal., Int J Biochem Cell Biol. 2009 May;41(5):994-7. doi: 10.1016/j.biocel.2008.07.017. Epub 2008 Aug 8.
35. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
36. Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin. Pekny M, etal., J Cell Biol. 1999 May 3;145(3):503-14.
37. Proteomic analysis of circulating human monocytes in coronary artery disease. Poduri A, etal., Mol Cell Biochem. 2012 Jan;360(1-2):181-8. Epub 2011 Sep 22.
38. Endothelial-to-mesenchymal transition in pulmonary hypertension. Ranchoux B, etal., Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.
39. GOA pipeline RGD automated data pipeline
40. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
41. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
42. Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma. Roymans D, etal., Exp Cell Res. 2000 Nov 25;261(1):127-38.
43. Transmission electron microscopic demonstration of vimentin in rat osteoblast and osteocyte cell bodies and processes using the immunogold technique. Shapiro F, etal., Anat Rec. 1995 Jan;241(1):39-48.
44. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
45. Arterialization and anomalous vein wall remodeling in varicose veins is associated with upregulated FoxC2-Dll4 pathway. Surendran S, etal., Lab Invest. 2016 Apr;96(4):399-408. doi: 10.1038/labinvest.2015.167. Epub 2016 Jan 25.
46. Increasing vimentin expression associated with differentiation of human and rat preadipocytes. Teichert-Kuliszewska K, etal., Int J Obes Relat Metab Disord. 1996 Mar;20 Suppl 3:S108-13.
47. Ndel1 promotes axon regeneration via intermediate filaments. Toth C, etal., PLoS ONE. 2008 Apr 23;3(4):e2014.
48. Down-regulation of glial fibrillary acidic protein and vimentin by RNA interference improves acute urinary dysfunction associated with spinal cord injury in rats. Toyooka T, etal., J Neurotrauma. 2011 Apr;28(4):607-18. Epub 2011 Mar 24.
49. Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17beta-estradiol treatment. Upadhyay R, etal., Histochem Cell Biol. 2011 Nov;136(5):543-55. Epub 2011 Sep 14.
50. Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis. van de Stadt LA, etal., Arthritis Rheum. 2011 Nov;63(11):3226-33. doi: 10.1002/art.30537.
51. Proteome expression and carbonylation changes during trypanosoma cruzi infection and chagas disease in rats. Wen JJ and Garg NJ, Mol Cell Proteomics. 2011 Dec 22.
52. Elevated Orai1 and STIM1 expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer. Xia J, etal., Cancer Lett. 2016 Oct 10;381(1):31-40. doi: 10.1016/j.canlet.2016.07.014. Epub 2016 Jul 16.
53. Biologic Evaluation of Diabetes and Local Recurrence in Non-Small Cell Lung Cancer. Yang X, etal., Pathol Oncol Res. 2017 Jan;23(1):73-77. doi: 10.1007/s12253-016-0086-1. Epub 2016 Jul 13.
54. Hyperthyroidism in the developing rat testis is associated with oxidative stress and hyperphosphorylated vimentin accumulation. Zamoner A, etal., Mol Cell Endocrinol. 2007 Mar 15;267(1-2):116-26. Epub 2007 Jan 20.
55. Vimentin phosphorylation as a target of cell signaling mechanisms induced by 1alpha,25-dihydroxyvitamin D3 in immature rat testes. Zamoner A, etal., Steroids. 2008 Dec 22;73(14):1400-8. Epub 2008 Jul 17.
56. AMD3100 inhibits epithelial-mesenchymal transition, cell invasion, and metastasis in the liver and the lung through blocking the SDF-1α/CXCR4 signaling pathway in prostate cancer. Zhu WB, etal., J Cell Physiol. 2019 Jul;234(7):11746-11759. doi: 10.1002/jcp.27831. Epub 2018 Dec 7.
57. Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Zou J, etal., Virchows Arch. 2006 Apr;448(4):485-92. Epub 2006 Jan 18.
Additional References at PubMed
PMID:2493000   PMID:8188282   PMID:9150946   PMID:9305626   PMID:10625659   PMID:10816608   PMID:10852826   PMID:10989258   PMID:11487638   PMID:11889032   PMID:12177195   PMID:12244133  
PMID:12496370   PMID:12819359   PMID:14681019   PMID:14760703   PMID:15037121   PMID:15383276   PMID:15389538   PMID:15489334   PMID:15748847   PMID:15846844   PMID:15958512   PMID:15965470  
PMID:16052496   PMID:16128803   PMID:16169070   PMID:16493181   PMID:16629905   PMID:16769727   PMID:17050693   PMID:17485853   PMID:17881773   PMID:17882221   PMID:18178558   PMID:18198667  
PMID:18316471   PMID:18577232   PMID:19144319   PMID:19182904   PMID:19223297   PMID:19241870   PMID:19420356   PMID:19726676   PMID:20015863   PMID:20103531   PMID:20131911   PMID:20427712  
PMID:20458337   PMID:20479526   PMID:20603131   PMID:20617137   PMID:21139996   PMID:21245955   PMID:21266579   PMID:21343257   PMID:21362503   PMID:21423176   PMID:21426942   PMID:21746880  
PMID:21900206   PMID:21914078   PMID:22005459   PMID:22082260   PMID:22357929   PMID:22869704   PMID:22871113   PMID:22952236   PMID:23106098   PMID:23239537   PMID:23390484   PMID:23979707  
PMID:24057876   PMID:24728265   PMID:24874717   PMID:26170015   PMID:26377600   PMID:27021728   PMID:27335427   PMID:27812135   PMID:27919618   PMID:28169954   PMID:28705472   PMID:29476059  
PMID:29496907   PMID:29803674   PMID:31626376   PMID:31904090   PMID:35352799   PMID:38467554  


Genomics

Comparative Map Data
Vim
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81781,577,261 - 81,585,746 (+)NCBIGRCr8
mRatBN7.21776,668,701 - 76,677,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1776,668,647 - 76,677,187 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1780,141,211 - 80,149,708 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01783,976,613 - 83,985,110 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01778,024,506 - 78,033,003 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01780,882,715 - 80,891,200 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1780,882,666 - 80,891,212 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01782,500,898 - 82,509,383 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41787,847,280 - 87,855,763 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11787,858,112 - 87,866,596 (+)NCBI
Celera1776,037,845 - 76,046,329 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
VIM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381017,228,241 - 17,237,593 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1017,228,241 - 17,237,593 (+)EnsemblGRCh38hg38GRCh38
GRCh371017,270,240 - 17,279,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361017,311,304 - 17,319,598 (+)NCBINCBI36Build 36hg18NCBI36
Build 341017,311,308 - 17,319,594NCBI
Celera1017,203,520 - 17,212,854 (+)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1017,183,488 - 17,192,823 (+)NCBIHuRef
CHM1_11017,270,372 - 17,279,705 (+)NCBICHM1_1
T2T-CHM13v2.01017,246,786 - 17,256,137 (+)NCBIT2T-CHM13v2.0
Vim
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39213,579,122 - 13,587,637 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl213,578,738 - 13,587,637 (+)EnsemblGRCm39 Ensembl
GRCm38213,574,311 - 13,582,826 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl213,573,927 - 13,582,826 (+)EnsemblGRCm38mm10GRCm38
MGSCv37213,495,938 - 13,504,453 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36213,491,805 - 13,500,660 (+)NCBIMGSCv36mm8
Celera213,484,803 - 13,493,320 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map210.04NCBI
Vim
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,707,719 - 10,717,554 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542910,708,852 - 10,716,743 (-)NCBIChiLan1.0ChiLan1.0
VIM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2830,070,175 - 30,080,269 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11030,073,747 - 30,085,591 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01017,546,389 - 17,554,702 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11017,818,285 - 17,826,642 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1017,818,285 - 17,826,642 (+)Ensemblpanpan1.1panPan2
VIM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1219,671,316 - 19,679,367 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl219,671,316 - 19,679,466 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,774,615 - 16,782,665 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0219,962,890 - 19,970,942 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl219,941,383 - 19,970,947 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1217,165,331 - 17,173,380 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0218,003,247 - 18,011,326 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0218,621,519 - 18,629,571 (-)NCBIUU_Cfam_GSD_1.0
Vim
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934417,901,147 - 17,908,782 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493652010,052,012 - 10,059,182 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493652010,051,692 - 10,059,324 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VIM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1043,517,307 - 43,526,170 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11043,516,441 - 43,526,172 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21048,225,950 - 48,235,670 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VIM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1917,183,466 - 17,191,771 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl917,183,388 - 17,191,829 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605122,821,093 - 22,830,717 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vim
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,623,929 - 10,632,600 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479610,624,672 - 10,632,300 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vim
75 total Variants
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mirlet7drno-let-7d-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mir223rno-miR-223-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mirlet7brno-let-7b-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mirlet7a1rno-let-7a-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mir382rno-miR-382-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mir320arno-miR-320-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mir138-2rno-miR-138-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mirlet7irno-let-7i-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mirlet7c1rno-let-7c-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mir185rno-miR-185-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830
Mir129-2rno-miR-129-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Target Of
Summary Value
Count of predictions:28
Count of miRNA genes:28
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000024430
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)177177462182479847Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)177100332581153923Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat

Markers in Region
RH138541  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21776,667,933 - 76,668,083 (+)MAPPERmRatBN7.2
Rnor_6.01780,881,948 - 80,882,097NCBIRnor6.0
Rnor_5.01782,500,131 - 82,500,280UniSTSRnor5.0
RGSC_v3.41787,846,513 - 87,846,662UniSTSRGSC3.4
Celera1776,037,078 - 76,037,227UniSTS
RH 3.4 Map17773.0UniSTS
Cytogenetic Map17q12.3UniSTS
MARC_31619-31620:1062167711:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21776,674,598 - 76,675,170 (+)MAPPERmRatBN7.2
Rnor_6.01780,888,613 - 80,889,184NCBIRnor6.0
Rnor_5.01782,506,797 - 82,507,367UniSTSRnor5.0
RGSC_v3.41787,853,178 - 87,853,747UniSTSRGSC3.4
Celera1776,043,743 - 76,044,313UniSTS
Cytogenetic Map17q12.3UniSTS
VIM  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21776,672,814 - 76,673,022 (+)MAPPERmRatBN7.2
Rnor_6.01780,886,829 - 80,887,036NCBIRnor6.0
Rnor_5.01782,505,012 - 82,505,219UniSTSRnor5.0
RGSC_v3.41787,851,394 - 87,851,601UniSTSRGSC3.4
Celera1776,041,959 - 76,042,166UniSTS
Cytogenetic Map17q12.3UniSTS
VIM  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21776,672,805 - 76,673,055 (+)MAPPERmRatBN7.2
Rnor_6.01780,886,820 - 80,887,069NCBIRnor6.0
Rnor_5.01782,505,003 - 82,505,252UniSTSRnor5.0
RGSC_v3.41787,851,385 - 87,851,634UniSTSRGSC3.4
Celera1776,041,950 - 76,042,199UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000024430   ⟹   ENSRNOP00000024430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1776,668,647 - 76,677,187 (+)Ensembl
Rnor_6.0 Ensembl1780,882,666 - 80,891,212 (+)Ensembl
RefSeq Acc Id: NM_031140   ⟹   NP_112402
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81781,577,261 - 81,585,746 (+)NCBI
mRatBN7.21776,668,701 - 76,677,186 (+)NCBI
Rnor_6.01780,882,715 - 80,891,200 (+)NCBI
Rnor_5.01782,500,898 - 82,509,383 (+)NCBI
RGSC_v3.41787,847,280 - 87,855,763 (+)RGD
Celera1776,037,845 - 76,046,329 (+)RGD
Sequence:
RefSeq Acc Id: NP_112402   ⟸   NM_031140
- UniProtKB: P31000 (UniProtKB/Swiss-Prot),   G3V8C3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024430   ⟸   ENSRNOT00000024430
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P31000-F1-model_v2 AlphaFold P31000 1-466 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700597
Promoter ID:EPDNEW_R11120
Type:multiple initiation site
Name:Vim_1
Description:vimentin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01780,882,664 - 80,882,724EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621646 AgrOrtholog
BioCyc Gene G2FUF-8607 BioCyc
Ensembl Genes ENSRNOG00000018087 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055010730 UniProtKB/Swiss-Prot
  ENSRNOG00060008754 UniProtKB/Swiss-Prot
  ENSRNOG00065006791 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024430.6 UniProtKB/TrEMBL
  ENSRNOT00055018151 UniProtKB/Swiss-Prot
  ENSRNOT00060014653 UniProtKB/Swiss-Prot
  ENSRNOT00065010581 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Single helix bin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5621065 IMAGE-MGC_LOAD
InterPro IF_conserved UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Intermed_filament_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Intermediate_filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81818 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72372 IMAGE-MGC_LOAD
NCBI Gene 81818 ENTREZGENE
PANTHER GLIAL FIBRILLARY ACIDIC PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45652:SF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Filament_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Vim PhenoGen
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018087 RatGTEx
  ENSRNOG00055010730 RatGTEx
  ENSRNOG00060008754 RatGTEx
  ENSRNOG00065006791 RatGTEx
SMART Filament UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6JM43_RAT UniProtKB/TrEMBL
  A6JM44_RAT UniProtKB/TrEMBL
  A6JM45_RAT UniProtKB/TrEMBL
  A6JM46_RAT UniProtKB/TrEMBL
  G3V8C3 ENTREZGENE, UniProtKB/TrEMBL
  P31000 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Vim  vimentin      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Vim  vimentin      Symbol and Name status set to provisional 70820 PROVISIONAL