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Gene: Camkv (CaM kinase-like vesicle-associated) Rattus norvegicus

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Symbol:

Camkv

Name:

CaM kinase-like vesicle-associated

RGD ID:

621488

Description:

Enables calmodulin binding activity. Predicted to be involved in modulation of chemical synaptic transmission; regulation of modification of postsynaptic structure; and signal transduction. Is active in postsynapse. Orthologous to human CAMKV (CaM kinase like vesicle associated); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

1G5; caM kinase-like vesicle-associated protein; vesicle-associated calmodulin-binding protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CAMKV (CaM kinase like vesicle associated)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Camkv (CaM kinase-like vesicle-associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Camkv (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CAMKV (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CAMKV (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Camkv (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CAMKV (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CAMKV (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Camkv (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Camkv (CaM kinase like vesicle associated)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZNF580 (zinc finger protein 580)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	CAMKV (CaM kinase like vesicle associated)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Camkv (CaM kinase-like vesicle-associated)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	camkvb (CaM kinase-like vesicle-associated b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	camkvb (CaM kinase-like vesicle-associated b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	camkva (CaM kinase-like vesicle-associated a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	camkva (CaM kinase-like vesicle-associated a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CMK1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CMK2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	camkv	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	camkv	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,505,439 - 117,519,785 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	117,505,408 - 117,519,797 (+)	Ensembl				GRCr8
mRatBN7.2	8	108,626,821 - 108,641,169 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,626,821 - 108,641,169 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	114,253,270 - 114,267,608 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,452,457 - 112,466,932 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,295,233 - 110,309,571 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,715,755 - 116,730,061 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,715,755 - 116,730,061 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	116,070,039 - 116,084,385 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,205,817 - 113,220,164 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	107,940,559 - 107,945,614 (+)	NCBI		Celera
RGSC_v3.1	8	113,225,271 - 113,239,619 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbamazepine (ISO)

cefaloridine (EXP)

dorsomorphin (ISO)

Erionite (ISO)

ethylbenzene (ISO)

fenvalerate (EXP)

folic acid (ISO)

ivermectin (ISO)

linezolid (EXP)

manganese(II) chloride (EXP)

methapyrilene (ISO)

N-nitrosodiethylamine (ISO)

pentanal (ISO)

phenylmercury acetate (ISO)

propanal (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

Soman (EXP)

titanium dioxide (ISO)

toluene (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

modulation of chemical synaptic transmission (IEA,ISO)

regulation of modification of postsynaptic structure (IEA,ISO)

signal transduction (IBA)

Cellular Component

cytoplasm (IBA)

cytoplasmic vesicle (IEA)

cytoplasmic vesicle membrane (IEA)

glutamatergic synapse (IEA,ISO)

plasma membrane (IEA)

postsynapse (IDA,IEP)

synapse (IBA,IEA)

Molecular Function

ATP binding (IEA)

calcium/calmodulin-dependent protein kinase activity (IBA)

calmodulin binding (IBA,IDA,IEA)

protein kinase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	1G5: a calmodulin-binding, vesicle-associated, protein kinase-like protein enriched in forebrain neurites.	Godbout M, etal., J Neurosci 1994 Jan;14(1):1-13.
3.	The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines.	Liang Z, etal., Nat Commun. 2016 Oct 31;7:13282. doi: 10.1038/ncomms13282.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19292454	PMID:22871113	PMID:29476059	PMID:30053369

Genomics

Comparative Map Data

Camkv
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,505,439 - 117,519,785 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	117,505,408 - 117,519,797 (+)	Ensembl				GRCr8
mRatBN7.2	8	108,626,821 - 108,641,169 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,626,821 - 108,641,169 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	114,253,270 - 114,267,608 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,452,457 - 112,466,932 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,295,233 - 110,309,571 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,715,755 - 116,730,061 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,715,755 - 116,730,061 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	116,070,039 - 116,084,385 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	113,205,817 - 113,220,164 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	107,940,559 - 107,945,614 (+)	NCBI		Celera
RGSC_v3.1	8	113,225,271 - 113,239,619 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

CAMKV
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	49,857,989 - 49,869,906 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	49,857,214 - 49,869,935 (-)	Ensembl			hg38	GRCh38
GRCh37	3	49,895,422 - 49,907,339 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	49,870,426 - 49,882,373 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	3	49,861,230 - 49,873,180 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	49,953,963 - 49,965,913 (-)	NCBI		HuRef
CHM1_1	3	49,847,495 - 49,859,444 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	49,887,886 - 49,899,806 (-)	NCBI		T2T-CHM13v2.0

Camkv
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	107,813,097 - 107,826,882 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	107,812,873 - 107,826,890 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	107,935,851 - 107,949,691 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	107,935,674 - 107,949,691 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	107,838,251 - 107,852,022 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	107,794,021 - 107,807,792 (+)	NCBI		MGSCv36	mm8
Celera	9	107,544,336 - 107,558,113 (+)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	59.07	NCBI

Camkv
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	1,747,359 - 1,760,110 (-)	Ensembl
ChiLan1.0	NW_004955532	1,747,359 - 1,762,978 (-)	NCBI	ChiLan1.0	ChiLan1.0

CAMKV
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	49,844,266 - 49,859,224 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	49,849,041 - 49,863,999 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	49,789,838 - 49,801,795 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	51,026,103 - 51,038,318 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	51,026,111 - 51,038,064 (-)	Ensembl			panPan2	panpan1.1

CAMKV
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	39,413,050 - 39,428,973 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	39,424,519 - 39,427,612 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	39,333,870 - 39,349,820 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	39,770,112 - 39,785,847 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	39,773,588 - 39,785,831 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	39,136,939 - 39,152,883 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	39,541,389 - 39,557,131 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	39,820,724 - 39,836,679 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Camkv
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	64,705,961 - 64,719,275 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	1,464,716 - 1,479,808 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	1,466,460 - 1,479,798 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAMKV
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	32,381,128 - 32,392,987 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	32,381,122 - 32,401,480 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	35,561,866 - 35,573,720 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAMKV
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	11,264,349 - 11,276,616 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	11,263,584 - 11,276,543 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	155,720,753 - 155,733,134 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Camkv
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	3,775,969 - 3,788,020 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	3,775,961 - 3,805,137 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Camkv
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	99,268,387 - 99,282,770 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Camkv
134 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	519
Count of miRNA genes:	254
Interacting mature miRNAs:	329
Transcripts:	ENSRNOT00000025311
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	111249511	117802327	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

PMC126259P2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,640,093 - 108,640,174 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,728,986 - 116,729,066	NCBI	Rnor6.0
Rnor_5.0	8	116,083,310 - 116,083,390	UniSTS	Rnor5.0
RGSC_v3.4	8	113,219,089 - 113,219,169	UniSTS	RGSC3.4
Celera	8	107,944,539 - 107,944,619	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	8	55	157	78	74	46	84	46	6	311	169	11	135	79	81	28	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_024000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L22557	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000090239 ⟹ ENSRNOP00000071953

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	117,505,422 - 117,519,797 (+)	Ensembl
mRatBN7.2 Ensembl	8	108,626,821 - 108,641,169 (+)	Ensembl
Rnor_6.0 Ensembl	8	116,715,755 - 116,730,061 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116162 ⟹ ENSRNOP00000084923

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	117,505,422 - 117,519,797 (+)	Ensembl
mRatBN7.2 Ensembl	8	108,626,821 - 108,641,169 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000132912 ⟹ ENSRNOP00000102020

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	117,505,408 - 117,519,126 (+)	Ensembl

RefSeq Acc Id:

NM_024000 ⟹ NP_076490

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,505,439 - 117,519,785 (+)	NCBI
mRatBN7.2	8	108,626,821 - 108,641,169 (+)	NCBI
Rnor_6.0	8	116,715,755 - 116,730,061 (+)	NCBI
Rnor_5.0	8	116,070,039 - 116,084,385 (+)	NCBI
RGSC_v3.4	8	113,205,817 - 113,220,164 (+)	RGD
Celera	8	107,940,559 - 107,945,614 (+)	RGD

Sequence:

show sequence

AGTCGAAGCGGCTGCAGCTGGCGCCGCGTCTGCCCCGCGTGCCCGGAGCGGATTCTGCCGGCCG
CCCCCGGAGCCCTGCTGAGCCGGTTATCGCTTCCTGCCTGTGACCGACCAGCGTTGCAGAGCCT
AGCAATGCCGTTTGGTTGTGTGACTCTGGGTGACAAGAAGAACTATAACCAGCCATCGGAAGTG
ACTGACAGATATGATTTGGGACAAGTCGTCAAGACCGAGGAGTTTTGTGAAATCTTCCGGGCCA
AGGACAAGACAACAGGCAAGCTGCATACCTGCAAGAAATTCCAGAAGCGTGATGGCCGCAAGGT
TCGGAAGGCAGCCAAGAACGAGATTGGAATCCTGAAGATGGTAAAGCACCCCAACATCCTGCAG
CTGGTAGATGTGTTTGTGACCCGCAAAGAATACTTCATCTTTCTGGAGCTGGCCACGGGGAGGG
AGGTGTTTGACTGGATCCTGGACCAGGGCTACTACTCGGAGCGAGACACGAGCAACGTGGTGCG
GCAGGTCCTGGAGGCTGTGGCCTACTTGCACTCTCTCAAGATTGTGCACAGGAACCTCAAGCTA
GAAAACCTAGTGTACTACAACAGGCTAAAGAACTCAAAGATTGTCATCAGTGACTTTCACCTGG
CTAAGCTAGAGAACGGTCTTATCAAGGAGCCCTGTGGAACGCCGGAGTATCTGGCACCGGAAGT
GGTAGGACGGCAACGGTATGGACGTCCTGTGGATTGTTGGGCCATTGGTGTCATCATGTATATC
CTGCTTTCAGGCAACCCGCCCTTCTATGAGGAGGTAGAAGAAGATGACTATGAGAACCATGATA
AGAATCTCTTCCGCAAGATCCTCGCCGGTGACTATGAGTTTGACTCTCCGTACTGGGATGATAT
TTCTCAAGCAGCCAAAGACCTGGTCACAAGGCTGATGGAGGTGGAGCAAGACCAGCGGATCACC
GCCGAAGAGGCCATCTCCCATGAATGGATTTCTGGCAATGCAGCTTCTGATAAGAACATCAAGG
ATGGCGTCTGTGCCCAGATCGAGAAGAACTTTGCCAGAGCCAAGTGGAAGAAGGCCGTCCGAGT
GACCACTCTCATGAAGCGGCTCCGGGCACCAGAGCAGTCTGGAACGGCTGCTACTTCAGATGCT
GCCACTCCCGGGGCTGCTGGTGGGGCCGTCGCTGCAGCTGCAGGTGGAGCTGCCCCAGCCTCTG
GAGCCAGTGCTACTGTAGGCACAGGGGGTGATGCTGGGTGTGCAGCCAAGAGCGATGACATGGC
CTCTGCAGATCGTAGTGCCACCCCAGCCACAGATGGCAGTGCCACCCCAGCCACAGATGGCAGT
GTCACCCCAGCCACTGACGGGAGCATCACCCCAGCCACTGATGGGAGTGTCACTCCAGCTACTG
ACAGGAGTGCTACACCAGCTACTGATGGGAGAGCCACACCAGCCACAGAAGAGAGCACAGTGCC
CGCCGCTCAAAGCAGTGCCGCGCCAGCTGCAAAGGCAGCAGCCACCCCTGAGCCGGCTGTGGCC
CAGCCGGACAGCACAGCCCTAGAGGGTGCCACAGGCCAGGCTCCACCCTCTAGTAAAGGAGAAG
AGGCTACTGGCTGTGCCCAGGAGTCTCAGAGGGTGGAGACAAGCTGAATGGGCAGTCTGTTGGG
GGTTTTGAGGGATGGGAAGGAGGGTGGGAGTTTGGATGAGGGGCTTCTCACTGTATATAGAGTC
ACTGGCATGATGCCCTAGCTCCCCCCAAGCTCCCTCATCCCAGTGGGGCATGCCTGGGGGCCAT
GGGAGAGCAGTGTCGTCTCCTGTGTGGATGTATGTGAGTGGTGGGCAGGCCAGAGGCAGGGCCA
GCCCCAGCCCCTGCATGGATTCCTTGTGGCTTTCTGTCTTTCGCTAGCTTCACCAGTTTCTGTT
CCTTGTGGGATGCTGCTCTAGGGATACTCAGGGGGTCCTTGCTCTCCTTCCCTTCCCGTCTTCT
CATGTCCCCAGGCAGGCCCTGCAAGCCTCATACTTTCCCAGGCCCTAAATGGGTGGCCTTGCCC
TGAGAGCTGGTCCTCCAGCGAGGCCCTGTCAGCAGTGTTAGGCTCCTGCACACGAAGGTGTGTG
TACCTGTGGTGTTTGGGCTGCTCTAGGAGTAGATGCTGGCTGTAAAAGATGATGCAGAAATCTA
GGGCAGTGTGCTTTAAGTTAAGTCTGGTCACATGGTTGGGGGCAGGCACTGCATGTTAGCTGTG
GGGATCCTCAGAAGTGGGAGAGAGAATGGGTAGAAGCGTCCATCTTTTTCCCTGGGTGGGGGTG
GGGATCTTCCCTCTGAAGATCCTTGTGTTATTTCATAGCCTCCTGAGTCCTGTAGTGGGTTGCT
CTGCATCCTGATTCTTACGACACTCCAAAGGAAGAGAGAAACATGTTGGATGCAGCAGCGATGC
CTAGGAGAACAGAGTACAGGGCCAGCAGCACCAGTGCCCCAGCCTATCTGGGTCTTCTCTGTGA
GCGAGATAGGGAGGGCTGGTGTCCCCCATGGTCTTCCTAGATGCCACTACCAACGAAGAGACCT
TTCCCATAACCACCTCATGCAGGCTCAGGCCATAAATCCTCTTCCTCCCAGGGAGGCATGGCAG
TACCTCATAGGCTGCTTTGGGAGCTTGCTTTTCACAGCAGCAGATTTTCTGTTCTTCGTTCAGC
AATGCGGAGAGGCTTTACCTCTGTGTCTACTACCAGAGGCTGAGGTATCGCTCAGCCATGGGAT
GAGGAAGTAGAATAAGATTTCCCAGCTCCCTGAGGGATGCTCTCGGCAGGCACCCTTGGTCAGA
CTCTACCACAGCCTGCACAGGCAGCCACGCTGGTCCTTGCCCTTGCTCGGCACTCCATGGTGGT
ACTGCCCTTCTCCCTGCATGCCTGTGGGTCTGCTCTGGTATGTGAAGGTTGGTGGGCTAACTGT
GTGCCTGCTGAACCTGGCAAATAAACGTCACCCTGCAAAGCCTCTGGCCACCCTCTTGCCTTTG
CTTCCTCTGTCCTATTGGGGAGGAGCCTATGGAAGGCAGTGTGGGAGGGAAGAGGCCATGGGAG
CAGTTCCGGGTAGCGGCTGATGCTCAGTGCATTGCTTGGGGTAAGAGTGGAGGTCACCTTCTCC
GATGTGTACCTGGATGATGTTAATGGTAAATCCTCTGGGCTCAAAAAAACCATGAGTGGTGTGT
TTAAGCCAAGAAGTATCCCTAGCCGAGCACTGAAGGGCTGATGCTTTTCCAATTCTTGTTGACG
AAGAGCCTTTGTCTTAACTTGGACATAGAGGTGGAATCCACTCAGGGACAACCACTATAGGAAG
TGACCTTGTTCATGGGCACAGTGGGCCTCCTTGGGCTGGGGAGAAAGTGGGGTTGCACAAGTTT
TGTGCTGTATGTTGATGCCTACTTCCTGTGAATACCTGTGCTTTCCACTTAGACCAAAAAGATT
TCATTCTGTCTTCCCTGGCTGACGCAGACCTGCTTTATAATATGGAGTCATGTATGTTCCTTTT
GGGGGAGTAATATTGCTAATGATACTATAAAAATCCCTAAGGAGATTCGCTTCAACTCGGAGGG
GCTTTGGTAAACTCATCTGGGTTGCTTTCTCAGGGAGGACCTTAAATTATCTGATGTGGGAATA
ATAAAGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_076490	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA16633	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000071953
GenBank Protein	Q63092	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_076490 ⟸ NM_024000

- UniProtKB:

Q63092 (UniProtKB/Swiss-Prot), A0A0G2K1R5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPFGCVTLGDKKNYNQPSEVTDRYDLGQVVKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRKVR
KAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQ
VLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPCGTPEYLAPEVV
GRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDIS
QAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVT
TLMKRLRAPEQSGTAATSDAATPGAAGGAVAAAAGGAAPASGASATVGTGGDAGCAAKSDDMAS
ADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGRATPATEESTVPA
AQSSAAPAAKAAATPEPAVAQPDSTALEGATGQAPPSSKGEEATGCAQESQRVETS

hide sequence

Ensembl Acc Id:

ENSRNOP00000071953 ⟸ ENSRNOT00000090239

Ensembl Acc Id:

ENSRNOP00000084923 ⟸ ENSRNOT00000116162

Ensembl Acc Id:

ENSRNOP00000102020 ⟸ ENSRNOT00000132912

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63092-F1-model_v2	AlphaFold	Q63092	1-504	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621488	AgrOrtholog
BioCyc Gene	G2FUF-29167	BioCyc
Ensembl Genes	ENSRNOG00000058938	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000090239	ENTREZGENE
Gene3D-CATH	Phosphorylase Kinase, domain 1	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
InterPro	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:79011	UniProtKB/Swiss-Prot
NCBI Gene	79011	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN KINASE	UniProtKB/Swiss-Prot
Pfam	Pkinase	UniProtKB/Swiss-Prot
PhenoGen	Camkv	PhenoGen
PROSITE	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000058938	RatGTEx
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot
UniProt	A0A0G2K1R5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A2W9_RAT	UniProtKB/TrEMBL
	A0ABK0LA43_RAT	UniProtKB/TrEMBL
	CAMKV_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Camkv	CaM kinase-like vesicle-associated	1G5	vesicle-associated calmodulin-binding protein	Symbol and Name updated	1299863	APPROVED
2002-08-07	1G5	vesicle-associated calmodulin-binding protein			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_homology	has similarity to serine/threonine protein kinases	632251

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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