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Gene: Ica1 (islet cell autoantigen 1) Rattus norvegicus

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Symbol:

Ica1

Name:

islet cell autoantigen 1

RGD ID:

621465

Description:

Enables protein domain specific binding activity. Involved in regulation of protein-containing complex assembly. Located in Golgi apparatus; dendrite; and perinuclear region of cytoplasm. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ICA1 (islet cell autoantigen 1); PARTICIPATES IN type 1 diabetes mellitus pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

69 kDa islet cell autoantigen; ICA69; ICAp69; islet cell autoantigen 1, 69 kDa; islet cell autoantigen p69; p69

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ICA1 (islet cell autoantigen 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Ica1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ica1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ICA1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ICA1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ica1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ICA1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ICA1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ica1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ica1 (islet cell autoantigen 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ICA1 (islet cell autoantigen 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ica1 (islet cell autoantigen 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ica1 (islet cell autoantigen 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ica1 (islet cell autoantigen 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ICA69	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ICA69	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ric-19	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ric-19	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ica1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Candidate Gene For:

Gluco32 Gluco61

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	37,622,759 - 37,771,055 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	37,622,759 - 37,770,569 (-)	Ensembl				GRCr8
mRatBN7.2	4	36,656,475 - 36,804,705 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	36,656,475 - 36,804,298 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	41,623,730 - 41,765,233 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	37,549,925 - 37,691,432 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	35,962,394 - 36,103,901 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	34,635,509 - 34,780,187 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	34,635,506 - 34,780,193 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	34,493,594 - 34,639,924 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	33,680,878 - 33,830,443 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	32,158,705 - 32,303,677 (-)	NCBI		Celera
RGSC_v3.1	4	33,799,417 - 33,948,647 (-)	NCBI
Cytogenetic Map	4	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

diabetes mellitus (IDA)

type 1 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-acetamidofluorene (EXP)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

Benzo[ghi]perylene (ISO)

beta-lapachone (ISO)

beta-naphthoflavone (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butan-1-ol (ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

choline (ISO)

chrysene (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

cyclophosphamide (ISO)

DDE (ISO)

dexamethasone (ISO)

diethyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

Enterolactone (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

furan (EXP)

indole-3-methanol (EXP)

indometacin (ISO)

L-methionine (ISO)

menadione (ISO)

methylparaben (ISO)

N-nitrosodiethylamine (EXP,ISO)

okadaic acid (ISO)

ozone (ISO)

p-toluidine (EXP)

paracetamol (ISO)

pentanal (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

pirinixic acid (EXP)

propanal (ISO)

prothioconazole (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tetrachloromethane (EXP,ISO)

tetraphene (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vanadyl sulfate (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

membrane bending (IBA)

neurotransmitter transport (IEA)

regulation of protein-containing complex assembly (IMP)

regulation of secretion (IBA)

Cellular Component

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

cytosol (IEA,ISO,ISS)

dendrite (IDA)

endomembrane system (IEA)

Golgi membrane (IDA,IEA,ISO,ISS)

Golgi stack (IDA)

perinuclear region of cytoplasm (IDA)

secretory granule membrane (IBA,IEA,ISO,ISS)

synaptic vesicle membrane (IEA,ISO,ISS)

transport vesicle membrane (IEA)

Molecular Function

membrane curvature sensor activity (IBA,IEA,ISO)

protein binding (ISO)

protein domain specific binding (IEA,IMP)

Molecular Pathway Annotations Click to see Annotation Detail View

type 1 diabetes mellitus pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	PICK1-ICA69 heteromeric BAR domain complex regulates synaptic targeting and surface expression of AMPA receptors.	Cao M, etal., J Neurosci. 2007 Nov 21;27(47):12945-56.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Reduced thymic expression of islet antigen contributes to loss of self-tolerance.	Mathews CE, etal., Ann N Y Acad Sci. 2003 Nov;1005:412-7.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Cloning of human and rat p69 cDNA, a candidate autoimmune target in type 1 diabetes.	Miyazaki I, etal., Biochim Biophys Acta 1994 Oct 21;1227(1-2):101-4.
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus.	Roep BO, etal., Eur J Immunol. 1996 Jun;26(6):1285-9.
13.	Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells.	Spitzenberger F, etal., J Biol Chem 2003 Jul 11;278(28):26166-73.
14.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
15.	ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide.	Winer S, etal., J Immunol. 2002 Jan 1;168(1):475-82.

Additional References at PubMed

PMID:11029035	PMID:15489334	PMID:17213368	PMID:20530722	PMID:25392508	PMID:29768204

Genomics

Comparative Map Data

Ica1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	37,622,759 - 37,771,055 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	37,622,759 - 37,770,569 (-)	Ensembl				GRCr8
mRatBN7.2	4	36,656,475 - 36,804,705 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	36,656,475 - 36,804,298 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	41,623,730 - 41,765,233 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	37,549,925 - 37,691,432 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	35,962,394 - 36,103,901 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	34,635,509 - 34,780,187 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	34,635,506 - 34,780,193 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	34,493,594 - 34,639,924 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	33,680,878 - 33,830,443 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	32,158,705 - 32,303,677 (-)	NCBI		Celera
RGSC_v3.1	4	33,799,417 - 33,948,647 (-)	NCBI
Cytogenetic Map	4	q21	NCBI

ICA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	8,113,184 - 8,262,555 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	8,113,181 - 8,262,687 (-)	Ensembl			hg38	GRCh38
GRCh37	7	8,152,814 - 8,302,185 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	8,119,339 - 8,268,710 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	7,926,643 - 8,075,008	NCBI
Celera	7	8,120,520 - 8,269,877 (-)	NCBI		Celera
Cytogenetic Map	7	p21.3	NCBI
HuRef	7	8,002,616 - 8,152,148 (-)	NCBI		HuRef
CHM1_1	7	8,152,546 - 8,301,969 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	8,231,684 - 8,381,157 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	8,198,979 - 8,348,384 (-)	NCBI

Ica1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	8,630,527 - 8,778,531 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	8,630,527 - 8,778,488 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	8,630,527 - 8,778,540 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	8,630,527 - 8,778,488 (-)	Ensembl			mm10	GRCm38
MGSCv37	6	8,580,527 - 8,728,484 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	8,580,527 - 8,728,095 (-)	NCBI		MGSCv36	mm8
Celera	6	8,763,268 - 8,911,580 (-)	NCBI		Celera
Cytogenetic Map	6	A1	NCBI
cM Map	6	4.38	NCBI

Ica1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	15,136,757 - 15,269,125 (-)	Ensembl
ChiLan1.0	NW_004955432	15,136,606 - 15,297,415 (-)	NCBI	ChiLan1.0	ChiLan1.0

ICA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	13,013,277 - 13,167,399 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	61,337,989 - 61,492,116 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	8,838,319 - 8,992,433 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	8,187,748 - 8,340,829 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	8,188,479 - 8,314,556 (-)	Ensembl			panPan2	panpan1.1

ICA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	23,673,739 - 23,816,850 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	23,673,758 - 23,796,462 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	23,248,756 - 23,391,657 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	23,488,679 - 23,631,110 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	23,483,120 - 23,630,707 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	23,640,101 - 23,783,180 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	23,379,186 - 23,521,194 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	23,631,393 - 23,773,055 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ica1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	37,005,982 - 37,151,681 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936585	1,711,976 - 1,857,861 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936585	1,711,863 - 1,857,861 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ICA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	78,332,393 - 78,515,087 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	78,364,478 - 78,515,092 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	86,173,296 - 86,215,276 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ICA1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	49,938,697 - 50,094,024 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	49,938,503 - 50,093,874 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666042	54,304,161 - 54,461,847 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ica1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	5,739,302 - 5,871,039 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624813	5,739,394 - 5,896,212 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ica1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	129,657,781 - 129,793,304 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ica1
1308 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	141
Count of miRNA genes:	115
Interacting mature miRNAs:	118
Transcripts:	ENSRNOT00000011651
Prediction methods:	Microtar, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2302371	Stl22	Serum triglyceride level QTL 22	5.15		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	13080146	58080146	Rat
2303585	Bw86	Body weight QTL 86	4		body mass (VT:0001259)	body weight (CMO:0000012)	4	15644309	60644309	Rat
5685012	Bmd87	Bone mineral density QTL 87	5.1		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	4	35113290	80113290	Rat
8552906	Pigfal3	Plasma insulin-like growth factor 1 level QTL 3			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	4	11038706	56038706	Rat
8655949	Rf62	Renal function QTL 62	22		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	4	35396600	45429897	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
6478766	Anxrr47	Anxiety related response QTL 47		0.09637	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	11038706	56038706	Rat
70222	Eae2	Experimental allergic encephalomyelitis QTL 2	4.3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	4	22288453	40471598	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	26234499	134199155	Rat
631642	Stl2	Serum triglyceride level QTL 2	3.3		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5894575	57613242	Rat
6478769	Anxrr48	Anxiety related response QTL 48		0.02514	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	11038706	56038706	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	11706604	92690519	Rat
2313401	Anxrr27	Anxiety related response QTL 27			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	4	18900697	63900697	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	37269577	82269577	Rat
631209	Bw2	Body weight QTL2	4.2		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	1	45429897	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	27862204	126119996	Rat
8694374	Bw155	Body weight QTL 155	3.39	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	4	11038706	56038706	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5889999	148002343	Rat
61412	Pia2	Pristane induced arthritis QTL 2	3.9		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	4	22288453	63245191	Rat
8552807	Vie4	Viral induced encephalitis QTL 4	7.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	18900697	63900697	Rat
6478724	Anxrr35	Anxiety related response QTL 35		0.00449	defecation behavior trait (VT:0010462)	defecation measurement (CMO:0000997)	4	11038706	56038706	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	30448961	82336920	Rat
61415	Eae11	Experimental allergic encephalomyelitis QTL 11	2.9		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	4	1	40471598	Rat
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5889999	50889999	Rat
7387227	Uae40	Urinary albumin excretion QTL 40	2.9	0.0052	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	18913151	63913151	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	27862204	62997402	Rat
1358203	Stl19	Serum triglyceride level QTL 19	2.8	0.002	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	21925151	66925151	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	1	63900697	Rat
9590304	Scort17	Serum corticosterone level QTL 17	4.96	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	11038706	56038706	Rat
11530004	Niddm71	Non-insulin dependent diabetes mellitus QTL 71		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	4	33538816	53719714	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	33538597	116185060	Rat
1354665	Stl10	Serum triglyceride level QTL 10	3.57		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	22288453	45429897	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
1300141	Bp178	Blood pressure QTL 178			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	10758701	40490708	Rat

Markers in Region

D4Got205

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	36,750,101 - 36,750,323 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	34,725,599 - 34,725,820	NCBI	Rnor6.0
Rnor_5.0	4	34,584,684 - 34,584,905	UniSTS	Rnor5.0
RGSC_v3.4	4	33,775,174 - 33,775,395	UniSTS	RGSC3.4
Celera	4	32,249,385 - 32,249,609	UniSTS
Cytogenetic Map	4	q21	UniSTS

BF419765

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	36,738,868 - 36,739,055 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	34,714,016 - 34,714,202	NCBI	Rnor6.0
Rnor_5.0	4	34,573,101 - 34,573,287	UniSTS	Rnor5.0
RGSC_v3.4	4	33,763,941 - 33,764,127	UniSTS	RGSC3.4
Celera	4	32,238,183 - 32,238,369	UniSTS
RH 3.4 Map	4	200.0	UniSTS
Cytogenetic Map	4	q21	UniSTS

AA800371

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	36,788,748 - 36,788,912 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	34,764,181 - 34,764,344	NCBI	Rnor6.0
Rnor_5.0	4	34,623,932 - 34,624,095	UniSTS	Rnor5.0
RGSC_v3.4	4	33,814,557 - 33,814,720	UniSTS	RGSC3.4
Celera	4	32,287,791 - 32,287,954	UniSTS
RH 3.4 Map	4	200.5	UniSTS
Cytogenetic Map	4	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	86	59	6	350	186	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_030844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236095	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC063810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L20900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011651 ⟹ ENSRNOP00000011651

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	37,622,759 - 37,770,569 (-)	Ensembl
mRatBN7.2 Ensembl	4	36,656,475 - 36,804,298 (-)	Ensembl
Rnor_6.0 Ensembl	4	34,635,506 - 34,780,193 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000077329 ⟹ ENSRNOP00000075191

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	37,622,759 - 37,770,569 (-)	Ensembl
mRatBN7.2 Ensembl	4	36,656,475 - 36,804,298 (-)	Ensembl
Rnor_6.0 Ensembl	4	34,635,509 - 34,779,776 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100899 ⟹ ENSRNOP00000086969

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	37,622,759 - 37,770,569 (-)	Ensembl
mRatBN7.2 Ensembl	4	36,656,475 - 36,804,298 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118007 ⟹ ENSRNOP00000095862

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	37,622,759 - 37,749,511 (-)	Ensembl
mRatBN7.2 Ensembl	4	36,656,475 - 36,783,242 (-)	Ensembl

RefSeq Acc Id:

NM_030844 ⟹ NP_110471

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,905 (-)	NCBI
mRatBN7.2	4	36,656,475 - 36,804,634 (-)	NCBI
Rnor_6.0	4	34,635,509 - 34,780,107 (-)	NCBI
Rnor_5.0	4	34,493,594 - 34,639,924 (-)	NCBI
RGSC_v3.4	4	33,680,878 - 33,830,443 (-)	RGD
Celera	4	32,158,705 - 32,303,677 (-)	RGD

Sequence:

show sequence

CGGGAAGACCCCAGGGAGTAGAGAGAGGGACACTCACGCCTCTCATCCCTGATCCGCCCCAAAC
AAGGAAAATGGTTCGATGTTATTAAAAATGAATCTTAAGAAGAAAAATGAATCACAGCAGTTAA
ACTATGGAGTTCTGCTACTTGTAAGAAGTGGAGAAGCCTGAGATTACATCACTGACCCTTGATC
CTCCACTGAGCTAAAACACCAGCTGGTTTAATAGAACATATCCTATCATGCTTTTTCTCTGCCC
CTTCTCAAATCATCAGCAGTAGAAAAGAGAAGAAAACATGTCAGGACACAAATGTTATTCCTGG
GAGTTGCAGGATCGGTTTGCTCAAGATAAGTCAGTTGTCAATAAGATGCAACAGAAATATTGGG
AAACGAAGCAGGCCTTTATCAAAGCCACAGGGAAGAAGGAAGATGAACATGTCGTTGCTTCTGA
TGCAGACCTGGATGCCAAGCTAGAGCTGTTTCATTCGATTCAGAGAACCTGTTTGGACTTGTCT
AAAGCAATTGTGCTCTATCAAAAGAGAATATGTTTCTTGTCTCAAGAAGAAAATGAACTGGGAA
AATTTCTCCGATCCCAAGGCTTCCAGGACAAAACCCGAGCAGGAAAAATGATGCAAGCCACAGG
AAAGGCCCTCTGCTTTTCCTCCCAGCAAAGGTTGGCCTTGAGAAACCCTTTGTGTCGATTTCAC
CAAGAAGTAGAGACTTTTAGACATCGGGCCATCTCCGATACCTGGCTGACAGTGAACCGCATGG
AGCAGTGCCGGACAGAATATAGAGGGGCGTTATTGTGGATGAAGGACGTGTCTCAGGAACTGGA
TCCAGACCTCTACAAGCAAATGGAGAAGTTCAGGAAGGTACAGACACAAGTCCGCCTCGCGAAG
AAGAACTTTGACAAATTGAAGATGGATGTGTGTCAAAAGGTGGATCTTCTTGGAGCAAGCAGAT
GTAACCTCTTATCTCACATGCTAGCAACATATCAGACCACTCTGCTCCACTTTTGGGAGAAAAC
TTCTCACACCATGGCAGCCATCCATGAGAGCTTCAAAGGCTATCAACCATATGAATTCACAACG
TTAAAGAGCTTACAAGACCCTATGAAAAAGCTAGTCGAGAAAGAAAAGAAGAAGAGCTCCCGGA
GGGAAAACCGGGAGGCTGTGGCACAGGAGCCGAGGCAGTTAATTTCATTGGAGGAAGAGAACCA
GCACAAAGAATCCTCTACTTGCCAGACGGAGGAGGGAAAAAGCGTTCCGTCTTCTGTAGACAAA
AGTTCTGCAGATGATGCATGCTCAGGACCCATAGATGAACTATTAGACGTGAAACCTGAGGAAG
CTTGCCTGGGTCCCATGGCAGGGACCCCAGAACCTGAAAGTGGGGACAAGGACGACCTCCTGCT
GTTGAACGAGATCTTCAGCACTTCCAGCCTGGATGAAGGGGAGTTCAGCAGGGAGTGGGCTGCG
GTGTTCGGAGACGACCGGCTGAAGGAACCAGCCCCCATGGGGGCCCAGGGAGAGCCAGACCCCA
AGCCCCAGATAGGCTCTGCGTTCCTTCCTTCACAGCTTTTAGACCAAAACATGAAAGATCTCCA
GGCCTCTCTCCAAGAGCCTGCCAAGGCTGCCTCGGACCTGACTGCCTGGTTCAGCCTCTTTGCT
GACCTCGACCCCCTATCAAATCCTGATGCTATTGGGAAAACCGATAAAGAACACGAATTGCTCA
ATGCATGAGTCTGCAACCTTCAACAGGGGAGCCCTCCGGCCACTCCGCAACACCTCATCCAGGG
CTTGCAGAAGTCTAACGTGCTCAGTACGCTGTTTTAATATTTACATGCCATTTTAATAAAACGA
GAGGGTCAAGGCCCTGTTTCTATCGCTATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006236092 ⟹ XP_006236154

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,716 (-)	NCBI
mRatBN7.2	4	36,656,475 - 36,804,425 (-)	NCBI
Rnor_6.0	4	34,635,509 - 34,779,908 (-)	NCBI
Rnor_5.0	4	34,493,594 - 34,639,924 (-)	NCBI

Sequence:

show sequence

CTGCGCTGCGGCGCGCACAGGCTCCGGGCTGCTATTCCGGCTGGCGGCGGCCGCTGCAGGAAGG
ACCGCTTCCTGCGCTCCCCGCCCCTTCCCTCGCCAGTGCTGACGCTGACGTCGGCGCAGGGAGC
TGGAGGGACGCTCCGATCTCCGCTGAGAGGCTCCTGGGGGCCGGGGCTCCGAGGAAAATGGTTC
GATGTTATTAAAAATGAATCTTAAGAAGAAAAATGAATCACAGCAGTTAAACTATGGAGTTCTG
CTACTTGTAAGAAGTGGAGAAGCCTGAGATTACATCACTGACCCTTGATCCTCCACTGAGCTAA
AACACCAGCTGGTTTAATAGAACATATCCTATCATGCTTTTTCTCTGCCCCTTCTCAAATCATC
AGCAGTAGAAAAGAGAAGAAAACATGTCAGGACACAAATGTTATTCCTGGGAGTTGCAGGATCG
GTTTGCTCAAGATAAGTCAGTTGTCAATAAGATGCAACAGAAATATTGGGAAACGAAGCAGGCC
TTTATCAAAGCCACAGGGAAGAAGGAAGATGAACATGTCGTTGCTTCTGATGCAGACCTGGATG
CCAAGCTAGAGCTGTTTCATTCGATTCAGAGAACCTGTTTGGACTTGTCTAAAGCAATTGTGCT
CTATCAAAAGAGAATATGTTTCTTGTCTCAAGAAGAAAATGAACTGGGAAAATTTCTCCGATCC
CAAGGCTTCCAGGACAAAACCCGAGCAGGAAAAATGATGCAAGCCACAGGAAAGGCCCTCTGCT
TTTCCTCCCAGCAAAGGTTGGCCTTGAGAAACCCTTTGTGTCGATTTCACCAAGAAGTAGAGAC
TTTTAGACATCGGGCCATCTCCGATACCTGGCTGACAGTGAACCGCATGGAGCAGTGCCGGACA
GAATATAGAGGGGCGTTATTGTGGATGAAGGACGTGTCTCAGGAACTGGATCCAGACCTCTACA
AGCAAATGGAGAAGTTCAGGAAGGTACAGACACAAGTCCGCCTCGCGAAGAAGAACTTTGACAA
ATTGAAGATGGATGTGTGTCAAAAGGTGGATCTTCTTGGAGCAAGCAGATGTAACCTCTTATCT
CACATGCTAGCAACATATCAGACCACTCTGCTCCACTTTTGGGAGAAAACTTCTCACACCATGG
CAGCCATCCATGAGAGCTTCAAAGGCTATCAACCATATGAATTCACAACGTTAAAGAGCTTACA
AGACCCTATGAAAAAGCTAGTCGAGAAAGAAAAGAAGAAGAGCTCCCGGAGGGAAAACCGGGAG
GCTGTGGCACAGGAGCCGAGGCAGTTAATTTCATTGGAGGAAGAGAACCAGCACAAAGAATCCT
CTACTTGCCAGACGGAGGAGGGAAAAAGCGTTCCGTCTTCTGTAGACAAAAGTTCTGCAGATGA
TGCATGCTCAGGACCCATAGATGAACTATTAGACGTGAAACCTGAGGAAGCTTGCCTGGGTCCC
ATGGCAGGGACCCCAGAACCTGAAAGTGGGGACAAGGACGACCTCCTGCTGTTGAACGAGATCT
TCAGCACTTCCAGCCTGGATGAAGGGGAGTTCAGCAGGGAGTGGGCTGCGGTGTTCGGAGACGA
CCGGCTGAAGGAACCAGCCCCCATGGGGGCCCAGGGAGAGCCAGACCCCAAGCCCCAGATAGGC
TCTGCGTTCCTTCCTTCACAGCTTTTAGACCAAAACATGAAAGATCTCCAGGCCTCTCTCCAAG
AGCCTGCCAAGGCTGCCTCGGACCTGACTGCCTGGTTCAGCCTCTTTGCTGACCTCGACCCCCT
ATCAAATCCTGATGCTATTGGGAAAACCGATAAAGAACACGAATTGCTCAATGCATGAGTCTGC
AACCTTCAACAGGGGAGCCCTCCGGCCACTCCGCAACACCTCATCCAGGGCTTGCAGAAGTCTA
ACGTGCTCAGTACGCTGTTTTAATATTTACATGCCATTTTAATAAAACGAGAGGGTCAAGGCCC
TGTTTCTATCGCTATA

hide sequence

RefSeq Acc Id:

XM_006236093 ⟹ XP_006236155

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,709 (-)	NCBI
mRatBN7.2	4	36,656,475 - 36,804,426 (-)	NCBI
Rnor_6.0	4	34,635,509 - 34,779,908 (-)	NCBI
Rnor_5.0	4	34,493,594 - 34,639,924 (-)	NCBI

Sequence:

show sequence

CTGCGCTGCGGCGCGCACAGGCTCCGGGCTGCTATTCCGGCTGGCGGCGGCCGCTGCAGGAAGG
ACCGCTTCCTGCGCTCCCCGCCCCTTCCCTCGCCAGTGCTGACGCTGACGTCGGCGCAGGGAGC
TGGAGGGACGCTCCGATCTCCGCTGAGAGGCTCCTGGGGGCCGGGGCTCCGAGGAAAATGGTTC
GATGTTATTAAAAATGAATCTTAAGAAGAAAAATGAATCACAGCAGTTAAACTATGGAGTTCTG
CTACTTGTAAGAAGTGGAGAAGCCTGAGATTACATCACTGACCCTTGATCCTCCACTGAGCTAA
AACACCAGCTGGTAATTGCCTATGATTTTATAGACTTCCCTCCATCTGCTGGGTCCAAGTGTCC
GTCTGACTGCTCTGGTACCGGAGCATCTTTATTTCTGCATCTAAACTTGTAAAAAGCACATCGA
ATCTTGTTCCCCAGGAGAAAATCTTCAATGTAACCATTTTCAATGTATCCGATGATACAAGCGC
ATTGTAATCTCCAGGTAGAAGCAGCTTTATCAGTGGAAAGGGTTTAATAGAACATATCCTATCA
TGCTTTTTCTCTGCCCCTTCTCAAATCATCAGCAGTAGAAAAGAGAAGAAAACATGTCAGGACA
CAAATGTTATTCCTGGGAGTTGCAGGATCGGTTTGCTCAAGATAAGTCAGTTGTCAATAAGATG
CAACAGAAATATTGGGAAACGAAGCAGGCCTTTATCAAAGCCACAGGGAAGAAGGAAGATGAAC
ATGTCGTTGCTTCTGATGCAGACCTGGATGCCAAGCTAGAGCTGTTTCATTCGATTCAGAGAAC
CTGTTTGGACTTGTCTAAAGCAATTGTGCTCTATCAAAAGAGAATATGTTTCTTGTCTCAAGAA
GAAAATGAACTGGGAAAATTTCTCCGATCCCAAGGCTTCCAGGACAAAACCCGAGCAGGAAAAA
TGATGCAAGCCACAGGAAAGGCCCTCTGCTTTTCCTCCCAGCAAAGGTTGGCCTTGAGAAACCC
TTTGTGTCGATTTCACCAAGAAGTAGAGACTTTTAGACATCGGGCCATCTCCGATACCTGGCTG
ACAGTGAACCGCATGGAGCAGTGCCGGACAGAATATAGAGGGGCGTTATTGTGGATGAAGGACG
TGTCTCAGGAACTGGATCCAGACCTCTACAAGCAAATGGAGAAGTTCAGGAAGGTACAGACACA
AGTCCGCCTCGCGAAGAAGAACTTTGACAAATTGAAGATGGATGTGTGTCAAAAGGTGGATCTT
CTTGGAGCAAGCAGATGTAACCTCTTATCTCACATGCTAGCAACATATCAGACCACTCTGCTCC
ACTTTTGGGAGAAAACTTCTCACACCATGGCAGCCATCCATGAGAGCTTCAAAGGCTATCAACC
ATATGAATTCACAACGTTAAAGAGCTTACAAGACCCTATGAAAAAGCTAGTCGAGAAAGAAAAG
AAGAAGAGCTCCCGGAGGGAAAACCGGGAGGCTGTGGCACAGGAGCCGAGGCAGTTAATTTCAT
TGGAGGAAGAGAACCAGCACAAAGAATCCTCTACTTGCCAGACGGAGGAGGGAAAAAGCGTTCC
GTCTTCTGTAGACAAAAGTTCTGCAGATGATGCATGCTCAGGACCCATAGATGAACTATTAGAC
GTGAAACCTGAGGAAGCTTGCCTGGGTCCCATGGCAGGGACCCCAGAACCTGAAAGTGGGGACA
AGGACGACCTCCTGCTGTTGAACGAGATCTTCAGCACTTCCAGCCTGGATGAAGGGGAGTTCAG
CAGGGAGTGGGCTGCGGTGTTCGGAGACGACCGGCTGAAGGAACCAGCCCCCATGGGGGCCCAG
GGAGAGCCAGACCCCAAGCCCCAGATAGGCTCTGCGTTCCTTCCTTCACAGCTTTTAGACCAAA
ACATGAAAGATCTCCAGGCCTCTCTCCAAGAGCCTGCCAAGGCTGCCTCGGACCTGACTGCCTG
GTTCAGCCTCTTTGCTGACCTCGACCCCCTATCAAATCCTGATGCTATTGGGAAAACCGATAAA
GAACACGAATTGCTCAATGCATGAGTCTGCAACCTTCAACAGGGGAGCCCTCCGGCCACTCCGC
AACACCTCATCCAGGGCTTGCAGAAGTCTAACGTGCTCAGTACGCTGTTTTAATATTTACATGC
CATTTTAATAAAACGAGAGGGTCAAGGCCCTGTTTCTATCGCTATA

hide sequence

RefSeq Acc Id:

XM_006236094 ⟹ XP_006236156

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,725 (-)	NCBI
mRatBN7.2	4	36,656,475 - 36,804,426 (-)	NCBI
Rnor_6.0	4	34,635,509 - 34,779,908 (-)	NCBI
Rnor_5.0	4	34,493,594 - 34,639,924 (-)	NCBI

Sequence:

show sequence

CTGCGCTGCGGCGCGCACAGGCTCCGGGCTGCTATTCCGGCTGGCGGCGGCCGCTGCAGGAAGG
ACCGCTTCCTGCGCTCCCCGCCCCTTCCCTCGCCAGTGCTGACGCTGACGTCGGCGCAGGGAGC
TGGAGGGACGCTCCGATCTCCGCTGAGAGGCTCCTGGGGGCCGGGGCTCCGAGGTTTAATAGAA
CATATCCTATCATGCTTTTTCTCTGCCCCTTCTCAAATCATCAGCAGTAGAAAAGAGAAGAAAA
CATGTCAGGACACAAATGTTATTCCTGGGAGTTGCAGGATCGGTTTGCTCAAGATAAGTCAGTT
GTCAATAAGATGCAACAGAAATATTGGGAAACGAAGCAGGCCTTTATCAAAGCCACAGGGAAGA
AGGAAGATGAACATGTCGTTGCTTCTGATGCAGACCTGGATGCCAAGCTAGAGCTGTTTCATTC
GATTCAGAGAACCTGTTTGGACTTGTCTAAAGCAATTGTGCTCTATCAAAAGAGAATATGTTTC
TTGTCTCAAGAAGAAAATGAACTGGGAAAATTTCTCCGATCCCAAGGCTTCCAGGACAAAACCC
GAGCAGGAAAAATGATGCAAGCCACAGGAAAGGCCCTCTGCTTTTCCTCCCAGCAAAGGTTGGC
CTTGAGAAACCCTTTGTGTCGATTTCACCAAGAAGTAGAGACTTTTAGACATCGGGCCATCTCC
GATACCTGGCTGACAGTGAACCGCATGGAGCAGTGCCGGACAGAATATAGAGGGGCGTTATTGT
GGATGAAGGACGTGTCTCAGGAACTGGATCCAGACCTCTACAAGCAAATGGAGAAGTTCAGGAA
GGTACAGACACAAGTCCGCCTCGCGAAGAAGAACTTTGACAAATTGAAGATGGATGTGTGTCAA
AAGGTGGATCTTCTTGGAGCAAGCAGATGTAACCTCTTATCTCACATGCTAGCAACATATCAGA
CCACTCTGCTCCACTTTTGGGAGAAAACTTCTCACACCATGGCAGCCATCCATGAGAGCTTCAA
AGGCTATCAACCATATGAATTCACAACGTTAAAGAGCTTACAAGACCCTATGAAAAAGCTAGTC
GAGAAAGAAAAGAAGAAGAGCTCCCGGAGGGAAAACCGGGAGGCTGTGGCACAGGAGCCGAGGC
AGTTAATTTCATTGGAGGAAGAGAACCAGCACAAAGAATCCTCTACTTGCCAGACGGAGGAGGG
AAAAAGCGTTCCGTCTTCTGTAGACAAAAGTTCTGCAGATGATGCATGCTCAGGACCCATAGAT
GAACTATTAGACGTGAAACCTGAGGAAGCTTGCCTGGGTCCCATGGCAGGGACCCCAGAACCTG
AAAGTGGGGACAAGGACGACCTCCTGCTGTTGAACGAGATCTTCAGCACTTCCAGCCTGGATGA
AGGGGAGTTCAGCAGGGAGTGGGCTGCGGTGTTCGGAGACGACCGGCTGAAGGAACCAGCCCCC
ATGGGGGCCCAGGGAGAGCCAGACCCCAAGCCCCAGATAGGCTCTGCGTTCCTTCCTTCACAGC
TTTTAGACCAAAACATGAAAGATCTCCAGGCCTCTCTCCAAGAGCCTGCCAAGGCTGCCTCGGA
CCTGACTGCCTGGTTCAGCCTCTTTGCTGACCTCGACCCCCTATCAAATCCTGATGCTATTGGG
AAAACCGATAAAGAACACGAATTGCTCAATGCATGAGTCTGCAACCTTCAACAGGGGAGCCCTC
CGGCCACTCCGCAACACCTCATCCAGGGCTTGCAGAAGTCTAACGTGCTCAGTACGCTGTTTTA
ATATTTACATGCCATTTTAATAAAACGAGAGGGTCAAGGCCCTGTTTCTATCGCTATA

hide sequence

RefSeq Acc Id:

XM_006236095 ⟹ XP_006236157

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,771,055 (-)	NCBI
mRatBN7.2	4	36,656,475 - 36,804,702 (-)	NCBI
Rnor_6.0	4	34,635,509 - 34,780,187 (-)	NCBI
Rnor_5.0	4	34,493,594 - 34,639,924 (-)	NCBI

Sequence:

show sequence

TGGAACACCTGCCAGAGAGCAGGGGCGGGGTCATCTCTGGCAGCAGGTCCAAAAGCCGGGTACC
CTAGAGATGGGGGTCACGGGAAGACCCCAGGGAGTAGAGAGAGGGACACTCACGCCTCTCATCC
CTGATCCGCCCCAAACAAGGTTTAATAGAACATATCCTATCATGCTTTTTCTCTGCCCCTTCTC
AAATCATCAGCAGTAGAAAAGAGAAGAAAACATGTCAGGACACAAATGTTATTCCTGGGAGTTG
CAGGATCGGTTTGCTCAAGATAAGTCAGTTGTCAATAAGATGCAACAGAAATATTGGGAAACGA
AGCAGGCCTTTATCAAAGCCACAGGGAAGAAGGAAGATGAACATGTCGTTGCTTCTGATGCAGA
CCTGGATGCCAAGCTAGAGCTGTTTCATTCGATTCAGAGAACCTGTTTGGACTTGTCTAAAGCA
ATTGTGCTCTATCAAAAGAGAATATGTTTCTTGTCTCAAGAAGAAAATGAACTGGGAAAATTTC
TCCGATCCCAAGGCTTCCAGGACAAAACCCGAGCAGGAAAAATGATGCAAGCCACAGGAAAGGC
CCTCTGCTTTTCCTCCCAGCAAAGGTTGGCCTTGAGAAACCCTTTGTGTCGATTTCACCAAGAA
GTAGAGACTTTTAGACATCGGGCCATCTCCGATACCTGGCTGACAGTGAACCGCATGGAGCAGT
GCCGGACAGAATATAGAGGGGCGTTATTGTGGATGAAGGACGTGTCTCAGGAACTGGATCCAGA
CCTCTACAAGCAAATGGAGAAGTTCAGGAAGGTACAGACACAAGTCCGCCTCGCGAAGAAGAAC
TTTGACAAATTGAAGATGGATGTGTGTCAAAAGGTGGATCTTCTTGGAGCAAGCAGATGTAACC
TCTTATCTCACATGCTAGCAACATATCAGACCACTCTGCTCCACTTTTGGGAGAAAACTTCTCA
CACCATGGCAGCCATCCATGAGAGCTTCAAAGGCTATCAACCATATGAATTCACAACGTTAAAG
AGCTTACAAGACCCTATGAAAAAGCTAGTCGAGAAAGAAAAGAAGAAGAGCTCCCGGAGGGAAA
ACCGGGAGGCTGTGGCACAGGAGCCGAGGCAGTTAATTTCATTGGAGGAAGAGAACCAGCACAA
AGAATCCTCTACTTGCCAGACGGAGGAGGGAAAAAGCGTTCCGTCTTCTGTAGACAAAAGTTCT
GCAGATGATGCATGCTCAGGACCCATAGATGAACTATTAGACGTGAAACCTGAGGAAGCTTGCC
TGGGTCCCATGGCAGGGACCCCAGAACCTGAAAGTGGGGACAAGGACGACCTCCTGCTGTTGAA
CGAGATCTTCAGCACTTCCAGCCTGGATGAAGGGGAGTTCAGCAGGGAGTGGGCTGCGGTGTTC
GGAGACGACCGGCTGAAGGAACCAGCCCCCATGGGGGCCCAGGGAGAGCCAGACCCCAAGCCCC
AGATAGGCTCTGCGTTCCTTCCTTCACAGCTTTTAGACCAAAACATGAAAGATCTCCAGGCCTC
TCTCCAAGAGCCTGCCAAGGCTGCCTCGGACCTGACTGCCTGGTTCAGCCTCTTTGCTGACCTC
GACCCCCTATCAAATCCTGATGCTATTGGGAAAACCGATAAAGAACACGAATTGCTCAATGCAT
GAGTCTGCAACCTTCAACAGGGGAGCCCTCCGGCCACTCCGCAACACCTCATCCAGGGCTTGCA
GAAGTCTAACGTGCTCAGTACGCTGTTTTAATATTTACATGCCATTTTAATAAAACGAGAGGGT
CAAGGCCCTGTTTCTATCGCTATA

hide sequence

RefSeq Acc Id:

XM_039108416 ⟹ XP_038964344

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,994 (-)	NCBI
mRatBN7.2	4	36,656,475 - 36,804,705 (-)	NCBI

RefSeq Acc Id:

XM_063286738 ⟹ XP_063142808

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,994 (-)	NCBI

RefSeq Acc Id:

XM_063286739 ⟹ XP_063142809

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,716 (-)	NCBI

RefSeq Acc Id:

XM_063286740 ⟹ XP_063142810

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,994 (-)	NCBI

RefSeq Acc Id:

XM_063286741 ⟹ XP_063142811

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,716 (-)	NCBI

RefSeq Acc Id:

XM_063286742 ⟹ XP_063142812

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,992 (-)	NCBI

RefSeq Acc Id:

XM_063286743 ⟹ XP_063142813

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	37,622,759 - 37,770,681 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_110471	(Get FASTA)	NCBI Sequence Viewer
	XP_006236154	(Get FASTA)	NCBI Sequence Viewer
	XP_006236155	(Get FASTA)	NCBI Sequence Viewer
	XP_006236156	(Get FASTA)	NCBI Sequence Viewer
	XP_006236157	(Get FASTA)	NCBI Sequence Viewer
	XP_038964344	(Get FASTA)	NCBI Sequence Viewer
	XP_063142808	(Get FASTA)	NCBI Sequence Viewer
	XP_063142809	(Get FASTA)	NCBI Sequence Viewer
	XP_063142810	(Get FASTA)	NCBI Sequence Viewer
	XP_063142811	(Get FASTA)	NCBI Sequence Viewer
	XP_063142812	(Get FASTA)	NCBI Sequence Viewer
	XP_063142813	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA64909	(Get FASTA)	NCBI Sequence Viewer
	AAH63810	(Get FASTA)	NCBI Sequence Viewer
	AAH78812	(Get FASTA)	NCBI Sequence Viewer
	EDM15065	(Get FASTA)	NCBI Sequence Viewer
	EDM15066	(Get FASTA)	NCBI Sequence Viewer
	EDM15067	(Get FASTA)	NCBI Sequence Viewer
	EDM15068	(Get FASTA)	NCBI Sequence Viewer
	EDM15069	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075191
	ENSRNOP00000086969
	ENSRNOP00000095862
GenBank Protein	Q63054	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_110471 ⟸ NM_030844

- UniProtKB:

Q6P3W0 (UniProtKB/Swiss-Prot), Q63054 (UniProtKB/Swiss-Prot), Q6AZ05 (UniProtKB/TrEMBL), A6IDX8 (UniProtKB/TrEMBL), A0A0G2K9Z2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHS
IQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLA
LRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRK
VQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFK
GYQPYEFTTLKSLQDPMKKLVEKEKKKSSRRENREAVAQEPRQLISLEEENQHKESSTCQTEEG
KSVPSSVDKSSADDACSGPIDELLDVKPEEACLGPMAGTPEPESGDKDDLLLLNEIFSTSSLDE
GEFSREWAAVFGDDRLKEPAPMGAQGEPDPKPQIGSAFLPSQLLDQNMKDLQASLQEPAKAASD
LTAWFSLFADLDPLSNPDAIGKTDKEHELLNA

hide sequence

RefSeq Acc Id:	XP_006236157 ⟸ XM_006236095
- Peptide Label:	isoform X1
- UniProtKB:	Q6P3W0 (UniProtKB/Swiss-Prot), Q63054 (UniProtKB/Swiss-Prot), Q6AZ05 (UniProtKB/TrEMBL), A6IDX8 (UniProtKB/TrEMBL), A0A0G2K9Z2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHS IQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLA LRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRK VQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFK GYQPYEFTTLKSLQDPMKKLVEKEKKKSSRRENREAVAQEPRQLISLEEENQHKESSTCQTEEG KSVPSSVDKSSADDACSGPIDELLDVKPEEACLGPMAGTPEPESGDKDDLLLLNEIFSTSSLDE GEFSREWAAVFGDDRLKEPAPMGAQGEPDPKPQIGSAFLPSQLLDQNMKDLQASLQEPAKAASD LTAWFSLFADLDPLSNPDAIGKTDKEHELLNA hide sequence

RefSeq Acc Id:	XP_006236156 ⟸ XM_006236094
- Peptide Label:	isoform X1
- UniProtKB:	Q6P3W0 (UniProtKB/Swiss-Prot), Q63054 (UniProtKB/Swiss-Prot), Q6AZ05 (UniProtKB/TrEMBL), A6IDX8 (UniProtKB/TrEMBL), A0A0G2K9Z2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHS IQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLA LRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRK VQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFK GYQPYEFTTLKSLQDPMKKLVEKEKKKSSRRENREAVAQEPRQLISLEEENQHKESSTCQTEEG KSVPSSVDKSSADDACSGPIDELLDVKPEEACLGPMAGTPEPESGDKDDLLLLNEIFSTSSLDE GEFSREWAAVFGDDRLKEPAPMGAQGEPDPKPQIGSAFLPSQLLDQNMKDLQASLQEPAKAASD LTAWFSLFADLDPLSNPDAIGKTDKEHELLNA hide sequence

RefSeq Acc Id:	XP_006236154 ⟸ XM_006236092
- Peptide Label:	isoform X1
- UniProtKB:	Q6P3W0 (UniProtKB/Swiss-Prot), Q63054 (UniProtKB/Swiss-Prot), Q6AZ05 (UniProtKB/TrEMBL), A6IDX8 (UniProtKB/TrEMBL), A0A0G2K9Z2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHS IQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLA LRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRK VQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFK GYQPYEFTTLKSLQDPMKKLVEKEKKKSSRRENREAVAQEPRQLISLEEENQHKESSTCQTEEG KSVPSSVDKSSADDACSGPIDELLDVKPEEACLGPMAGTPEPESGDKDDLLLLNEIFSTSSLDE GEFSREWAAVFGDDRLKEPAPMGAQGEPDPKPQIGSAFLPSQLLDQNMKDLQASLQEPAKAASD LTAWFSLFADLDPLSNPDAIGKTDKEHELLNA hide sequence

RefSeq Acc Id:	XP_006236155 ⟸ XM_006236093
- Peptide Label:	isoform X1
- UniProtKB:	Q6P3W0 (UniProtKB/Swiss-Prot), Q63054 (UniProtKB/Swiss-Prot), Q6AZ05 (UniProtKB/TrEMBL), A6IDX8 (UniProtKB/TrEMBL), A0A0G2K9Z2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGHKCYSWELQDRFAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHS IQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLA LRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRK VQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFK GYQPYEFTTLKSLQDPMKKLVEKEKKKSSRRENREAVAQEPRQLISLEEENQHKESSTCQTEEG KSVPSSVDKSSADDACSGPIDELLDVKPEEACLGPMAGTPEPESGDKDDLLLLNEIFSTSSLDE GEFSREWAAVFGDDRLKEPAPMGAQGEPDPKPQIGSAFLPSQLLDQNMKDLQASLQEPAKAASD LTAWFSLFADLDPLSNPDAIGKTDKEHELLNA hide sequence

Ensembl Acc Id:

ENSRNOP00000011651 ⟸ ENSRNOT00000011651

Ensembl Acc Id:

ENSRNOP00000075191 ⟸ ENSRNOT00000077329

RefSeq Acc Id:	XP_038964344 ⟸ XM_039108416
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A739 (UniProtKB/TrEMBL), A6IDX7 (UniProtKB/TrEMBL), F7FFT7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095862 ⟸ ENSRNOT00000118007

Ensembl Acc Id:

ENSRNOP00000086969 ⟸ ENSRNOT00000100899

RefSeq Acc Id:	XP_063142810 ⟸ XM_063286740
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A739 (UniProtKB/TrEMBL), A6IDX7 (UniProtKB/TrEMBL), F7FFT7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142808 ⟸ XM_063286738
- Peptide Label:	isoform X1
- UniProtKB:	Q6P3W0 (UniProtKB/Swiss-Prot), Q63054 (UniProtKB/Swiss-Prot), A0A0G2K9Z2 (UniProtKB/TrEMBL), A6IDX8 (UniProtKB/TrEMBL), Q6AZ05 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142812 ⟸ XM_063286742
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A739 (UniProtKB/TrEMBL), A6IDX7 (UniProtKB/TrEMBL), F7FFT7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142811 ⟸ XM_063286741
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A739 (UniProtKB/TrEMBL), A6IDX7 (UniProtKB/TrEMBL), F7FFT7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142809 ⟸ XM_063286739
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A739 (UniProtKB/TrEMBL), A6IDX7 (UniProtKB/TrEMBL), F7FFT7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063142813 ⟸ XM_063286743
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A739 (UniProtKB/TrEMBL), A6IDX7 (UniProtKB/TrEMBL), F7FFT7 (UniProtKB/TrEMBL)

Protein Domains

AH Islet cell autoantigen Ica1 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63054-F1-model_v2	AlphaFold	Q63054	1-480	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692880

Promoter ID:

EPDNEW_R3400

Type:

initiation region

Name:

Ica1_1

Description:

islet cell autoantigen 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R3401

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	34,779,810 - 34,779,870	EPDNEW

RGD ID:

13692876

Promoter ID:

EPDNEW_R3401

Type:

initiation region

Name:

Ica1_2

Description:

islet cell autoantigen 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R3400

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	34,780,155 - 34,780,215	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621465	AgrOrtholog
BioCyc Gene	G2FUF-45658	BioCyc
Ensembl Genes	ENSRNOG00000008628	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000077329	ENTREZGENE
	ENSRNOT00000100899	ENTREZGENE
	ENSRNOT00000118007	ENTREZGENE
Gene3D-CATH	1.20.1270.60	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:6921600	IMAGE-MGC_LOAD
	IMAGE:7112043	IMAGE-MGC_LOAD
InterPro	AH/BAR_dom_sf	UniProtKB/Swiss-Prot
	AH_dom	UniProtKB/Swiss-Prot
	Islet_autoAg_Ica1/Ica1-like	UniProtKB/Swiss-Prot
	Islet_autoAg_Ica1_C	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72803	IMAGE-MGC_LOAD
	MGC:93403	IMAGE-MGC_LOAD
NCBI Gene	81024	ENTREZGENE
PANTHER	PTHR10164	UniProtKB/Swiss-Prot
	PTHR10164:SF3	UniProtKB/Swiss-Prot
Pfam	Arfaptin	UniProtKB/Swiss-Prot
	ICA69	UniProtKB/Swiss-Prot
PhenoGen	Ica1	PhenoGen
PROSITE	PS50870	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008628	RatGTEx
SMART	Arfaptin	UniProtKB/Swiss-Prot
	ICA69	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF103657	UniProtKB/Swiss-Prot
UniProt	A0A0G2K9Z2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A739	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AQ00_RAT	UniProtKB/TrEMBL
	A6IDX7	ENTREZGENE, UniProtKB/TrEMBL
	A6IDX8	ENTREZGENE, UniProtKB/TrEMBL
	A6IDY0_RAT	UniProtKB/TrEMBL
	A6IDY2_RAT	UniProtKB/TrEMBL
	F7FFT7	ENTREZGENE, UniProtKB/TrEMBL
	ICA69_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6AZ05	ENTREZGENE
	Q6P3W0	ENTREZGENE
UniProt Secondary	Q6P3W0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-01-20	Ica1	islet cell autoantigen 1		islet cell autoantigen 1, 69 kDa	Name updated	1299863	APPROVED
2002-08-07	Ica1	islet cell autoantigen 1, 69 kDa			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	associated with membrane trafficking at the Golgi complex and immature secretory granules in neurosecretory cells	633043
gene_cellular_localization	associated with membrane trafficking at the Golgi complex and immature secretory granules in neurosecretory cells	724603
gene_expression	expressed in neurons and insulinoma INS-1 cells	724603
gene_protein	cytosolic protein 69 kDa in size	724603

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)