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Gene: Pi4kb (phosphatidylinositol 4-kinase beta) Rattus norvegicus

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Symbol:

Pi4kb

Name:

phosphatidylinositol 4-kinase beta

RGD ID:

621214

Description:

Enables 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in inner ear development; phosphatidylinositol phosphate biosynthetic process; and phosphatidylinositol-mediated signaling. Predicted to act upstream of or within lysosome organization. Predicted to be located in Golgi membrane. Predicted to be active in cytoplasm and membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 87. Orthologous to human PI4KB (phosphatidylinositol 4-kinase beta); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

catalytic phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, catalytic, beta; phosphatidylinositol 4-kinase, catalytic, beta polypeptide; PI4K-beta; PI4Kbeta; Pik4cb; ptdIns 4-kinase beta

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PI4KB (phosphatidylinositol 4-kinase beta)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pi4kb (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pi4kb (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PI4KB (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PI4KB (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pi4kb (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PI4KB (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PI4KB (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pi4kb (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pi4kb (phosphatidylinositol 4-kinase beta)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PI4KB (phosphatidylinositol 4-kinase beta)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pi4kb (phosphatidylinositol 4-kinase beta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pi4kb (phosphatidylinositol 4-kinase, catalytic, beta)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PIK1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PIK1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	fwd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	fwd	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pifk-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pifk-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pi4kb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	185,229,392 - 185,261,697 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	185,228,799 - 185,261,693 (+)	Ensembl				GRCr8
mRatBN7.2	2	182,540,377 - 182,572,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	182,540,567 - 182,588,488 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	190,205,165 - 190,237,217 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	188,000,894 - 188,032,951 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	182,837,647 - 182,869,695 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	196,139,724 - 196,172,055 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	196,139,755 - 196,171,713 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	215,634,003 - 215,666,743 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	189,874,613 - 189,906,640 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	175,082,416 - 175,114,456 (+)	NCBI		Celera
RGSC_v3.1	2	189,834,020 - 189,866,048 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant nonsyndromic deafness 87 (ISO)

Coronavirus infectious disease (ISO)

severe acute respiratory syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (EXP)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acetylsalicylic acid (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

Benzo[k]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

bortezomib (ISO)

caffeine (ISO)

cisplatin (ISO)

coumarin (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

dioxygen (ISO)

doxorubicin (ISO)

endosulfan (EXP)

enzyme inhibitor (ISO)

ethanol (EXP)

flavonoids (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP)

gentamycin (EXP)

indometacin (ISO)

lead(0) (ISO)

leflunomide (ISO)

methimazole (EXP)

methoxychlor (EXP)

nitrates (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

sulfadimethoxine (EXP)

sulforaphane (ISO)

tetracycline (ISO)

Tributyltin oxide (ISO)

triphenyl phosphate (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

inner ear development (IBA,IEA,ISO,ISS)

lipid metabolic process (IEA)

lysosome organization (ISO)

phosphatidylinositol phosphate biosynthetic process (IBA,IEA,ISO)

phosphatidylinositol-mediated signaling (IBA)

Cellular Component

cytoplasm (IBA)

cytoplasmic side of trans-Golgi network membrane (IEA,ISO)

endomembrane system (IEA)

Golgi apparatus (IEA,ISO)

Golgi membrane (IEA,ISO)

membrane (IBA)

mitochondrial outer membrane (IEA)

rough endoplasmic reticulum membrane (IEA)

Molecular Function

1-phosphatidylinositol 4-kinase activity (IBA,IDA,IEA,ISO,TAS)

14-3-3 protein binding (IEA,ISO,ISS)

ATP binding (IEA)

kinase activity (IEA)

nucleotide binding (IEA)

phosphatidylinositol kinase activity (IEA)

protein binding (IPI,ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

inositol phosphate metabolic pathway (IEA)

phosphatidylinositol 3-kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Overexpression of kidney phosphatidylinositol 4-kinasebeta and phospholipase C(gamma1) proteins in two rodent models of polycystic kidney disease.	Cuozzo FP, etal., Biochim Biophys Acta 2002 May 21;1587(1):99-106.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Cloning and characterization of a 92 kDa soluble phosphatidylinositol 4-kinase.	Nakagawa T, etal., Biochem J 1996 Dec 1;320 ( Pt 2):643-9.
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Neuronal calcium sensor 1 and phosphatidylinositol 4-OH kinase beta interact in neuronal cells and are translocated to membranes during nucleotide-evoked exocytosis.	Taverna E, etal., J Cell Sci. 2002 Oct 15;115(Pt 20):3909-22.

Additional References at PubMed

PMID:14607934	PMID:14607979	PMID:16638749	PMID:17088255	PMID:18474610	PMID:23572552	PMID:23899475	PMID:27009356

Genomics

Comparative Map Data

Pi4kb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	185,229,392 - 185,261,697 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	185,228,799 - 185,261,693 (+)	Ensembl				GRCr8
mRatBN7.2	2	182,540,377 - 182,572,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	182,540,567 - 182,588,488 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	190,205,165 - 190,237,217 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	188,000,894 - 188,032,951 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	182,837,647 - 182,869,695 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	196,139,724 - 196,172,055 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	196,139,755 - 196,171,713 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	215,634,003 - 215,666,743 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	189,874,613 - 189,906,640 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	175,082,416 - 175,114,456 (+)	NCBI		Celera
RGSC_v3.1	2	189,834,020 - 189,866,048 (+)	NCBI
Cytogenetic Map	2	q34	NCBI

PI4KB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	151,291,797 - 151,327,715 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	151,291,792 - 151,328,394 (-)	Ensembl			hg38	GRCh38
GRCh37	1	151,264,273 - 151,300,191 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	149,531,037 - 149,565,348 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	148,077,485 - 148,111,797	NCBI
Celera	1	124,379,704 - 124,414,015 (-)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	122,642,216 - 122,678,133 (-)	NCBI		HuRef
CHM1_1	1	152,660,019 - 152,695,935 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	150,415,490 - 150,452,405 (-)	NCBI		T2T-CHM13v2.0

Pi4kb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	94,882,042 - 94,914,248 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	94,882,042 - 94,914,154 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	94,974,731 - 95,006,937 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	94,974,731 - 95,006,843 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	94,778,653 - 94,810,765 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	95,060,140 - 95,091,993 (+)	NCBI		MGSCv36	mm8
Celera	3	96,405,996 - 96,438,094 (+)	NCBI		Celera
Cytogenetic Map	3	F2.1	NCBI
cM Map	3	40.74	NCBI

Pi4kb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955588	648,180 - 679,374 (-)	Ensembl
ChiLan1.0	NW_004955588	648,180 - 679,374 (-)	NCBI	ChiLan1.0	ChiLan1.0

PI4KB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	98,492,576 - 98,528,619 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	98,243,803 - 98,279,850 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	126,653,794 - 126,689,690 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	130,300,844 - 130,336,320 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	130,300,844 - 130,336,311 (-)	Ensembl			panPan2	panpan1.1

PI4KB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	60,359,545 - 60,386,093 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	60,360,236 - 60,384,778 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	59,803,028 - 59,830,272 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	61,375,750 - 61,403,019 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	61,375,754 - 61,402,452 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	60,203,634 - 60,230,882 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	60,289,810 - 60,317,042 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	61,018,193 - 61,044,694 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pi4kb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	22,465,447 - 22,493,491 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	1,495,833 - 1,523,276 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	1,495,833 - 1,523,307 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PI4KB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	97,918,245 - 97,949,931 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	97,918,234 - 97,949,929 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	107,119,069 - 107,150,710 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PI4KB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	12,358,758 - 12,395,372 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	12,358,762 - 12,394,661 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	11,933,446 - 11,970,304 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pi4kb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	18,532,986 - 18,564,492 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624772	18,533,603 - 18,564,160 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pi4kb
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	62,241,178 - 62,273,770 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pi4kb
259 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	54
Count of miRNA genes:	39
Interacting mature miRNAs:	52
Transcripts:	ENSRNOT00000040501
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	138595962	205135428	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	124537199	209621565	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	154723085	199723085	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	145807215	190807215	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	154723085	199723085	Rat
10043139	Iddm55	Insulin dependent diabetes mellitus QTL 55	3.1	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	150313808	195313808	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	154723085	199723085	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	205135267	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	154723085	199723085	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	171994826	205135428	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	143565208	188565208	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	154723085	199723085	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	139067258	192287892	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	184856304	229856304	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	184856304	229856304	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	159440760	195313808	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	144882354	205135428	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	184856304	229856304	Rat
1578671	Bmd10	Bone mineral density QTL 10	5.4		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	175931416	220931416	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	182024327	227024327	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	184482291	229482291	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	143746578	205135428	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150096616	195096616	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	113746222	205135428	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	147287892	192287892	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	117415288	205135428	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150096616	195096616	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	182635347	227635347	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	184856304	229856304	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	165453811	210453811	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	163253030	208253030	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat

Markers in Region

RH128413

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,572,291 - 182,572,511 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	196,171,665 - 196,171,884	NCBI	Rnor6.0
Rnor_5.0	2	215,666,351 - 215,666,570	UniSTS	Rnor5.0
RGSC_v3.4	2	189,906,523 - 189,906,742	UniSTS	RGSC3.4
Celera	2	175,114,339 - 175,114,558	UniSTS
RH 3.4 Map	2	1212.8	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH142980

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,569,398 - 182,569,609 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	196,168,772 - 196,168,982	NCBI	Rnor6.0
Rnor_5.0	2	215,663,458 - 215,663,668	UniSTS	Rnor5.0
RGSC_v3.4	2	189,903,630 - 189,903,840	UniSTS	RGSC3.4
Celera	2	175,111,446 - 175,111,656	UniSTS
RH 3.4 Map	2	1196.1	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH144445

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,540,402 - 182,540,529 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	196,139,781 - 196,139,907	NCBI	Rnor6.0
Rnor_5.0	2	215,634,467 - 215,634,593	UniSTS	Rnor5.0
RGSC_v3.4	2	189,874,639 - 189,874,765	UniSTS	RGSC3.4
Celera	2	175,082,442 - 175,082,568	UniSTS
RH 3.4 Map	2	1199.1	UniSTS
Cytogenetic Map	2	q34	UniSTS

MARC_27466-27467:1034353260:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	185,250,181 - 185,251,044 (+)	Marker Load Pipeline
mRatBN7.2	2	182,561,171 - 182,562,034 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	196,160,545 - 196,161,407	NCBI	Rnor6.0
Rnor_5.0	2	215,655,231 - 215,656,093	UniSTS	Rnor5.0
RGSC_v3.4	2	189,895,403 - 189,896,265	UniSTS	RGSC3.4
Celera	2	175,103,220 - 175,104,082	UniSTS
Cytogenetic Map	2	q34	UniSTS

D3Umi7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,549,029 - 182,549,846 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	196,148,406 - 196,149,222	NCBI	Rnor6.0
Rnor_5.0	2	215,643,092 - 215,643,908	UniSTS	Rnor5.0
RGSC_v3.4	2	189,883,264 - 189,884,080	UniSTS	RGSC3.4
Celera	2	175,091,071 - 175,091,887	UniSTS
Cytogenetic Map	2	q34	UniSTS

REN33561

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,571,864 - 182,572,134 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	196,171,238 - 196,171,507	NCBI	Rnor6.0
Rnor_5.0	2	215,665,924 - 215,666,193	UniSTS	Rnor5.0
RGSC_v3.4	2	189,906,096 - 189,906,365	UniSTS	RGSC3.4
Celera	2	175,113,912 - 175,114,181	UniSTS
Cytogenetic Map	2	q34	UniSTS

REN33651

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,549,344 - 182,549,598 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	196,148,721 - 196,148,974	NCBI	Rnor6.0
Rnor_5.0	2	215,643,407 - 215,643,660	UniSTS	Rnor5.0
RGSC_v3.4	2	189,883,579 - 189,883,832	UniSTS	RGSC3.4
Celera	2	175,091,386 - 175,091,639	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
20	12	84	213	91	90	59	145	59	6	465	271	20	191	107	124	31	34	34

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001439646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_031083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761333	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282632	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_591217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY724527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D84667	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000040501 ⟹ ENSRNOP00000039342

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	185,228,799 - 185,261,693 (+)	Ensembl
mRatBN7.2 Ensembl	2	182,548,848 - 182,588,488 (+)	Ensembl
Rnor_6.0 Ensembl	2	196,139,755 - 196,171,713 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000080966 ⟹ ENSRNOP00000070653

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	185,229,598 - 185,261,692 (+)	Ensembl
mRatBN7.2 Ensembl	2	182,540,567 - 182,572,680 (+)	Ensembl
Rnor_6.0 Ensembl	2	196,145,384 - 196,171,573 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103639 ⟹ ENSRNOP00000082231

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	185,229,380 - 185,261,693 (+)	Ensembl
mRatBN7.2 Ensembl	2	182,540,572 - 182,588,488 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112486 ⟹ ENSRNOP00000095998

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	185,229,564 - 185,260,870 (+)	Ensembl
mRatBN7.2 Ensembl	2	182,544,007 - 182,588,488 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112810 ⟹ ENSRNOP00000093461

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	185,229,380 - 185,261,693 (+)	Ensembl
mRatBN7.2 Ensembl	2	182,540,572 - 182,588,488 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118319 ⟹ ENSRNOP00000089657

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	185,229,619 - 185,261,693 (+)	Ensembl
mRatBN7.2 Ensembl	2	182,540,572 - 182,572,680 (+)	Ensembl

RefSeq Acc Id:

NM_031083 ⟹ NP_112345

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,392 - 185,261,419 (+)	NCBI
mRatBN7.2	2	182,540,377 - 182,572,409 (+)	NCBI
Rnor_6.0	2	196,139,755 - 196,171,782 (+)	NCBI
Rnor_5.0	2	215,634,003 - 215,666,743 (+)	NCBI
RGSC_v3.4	2	189,874,613 - 189,906,640 (+)	RGD
Celera	2	175,082,416 - 175,114,456 (+)	RGD

Sequence:

show sequence

TTACTATGGCATCGGTAGTGTCCTGACAGTTCGGAAAGCAGGAAAGCAAGCGCCGAGAAGAAAG
GCTCGGGCCCAGCGGACTCTTACATCGCAACCCATCAAGGAATTGTTATTTTGGGTCCTGCAAG
TGGGGTCCGGTCCAACTTGAGGTAGCGTGAAGGCCCCTTCAGGCGGCGCCGCGGGCAGCCCCGC
AGCCGGGGCCTGGTGCAGCCGCCGCGGCCGCTGTCAGGGAAGCGCAGGCGGCCAATGGAACCCG
GGAGCGGCCGCTGCTGCTGAGGCGGCGGTGTCGGCAGTCCGACCCCGACCGCCTGCACCCCCTC
CGCGAGGGTCCCCCGGAGCTTGGAAGCTCGAAGTCTGGCTGTAGCCATGGGAGACATGGTAGTG
GAGCCTGCCACCCTGAAGCCAACTTCTGAGCCTACTCCTAGCCCATCAGGGAATAACGGGGGCT
CCCTACTAAGCGTCATCACGGAGGGGGTCGGGGAACTGTCAGTGATTGACCCTGAGGTGGCCCA
GAAGGCCTGCCAGGAGGTACTGGAGAAAGTCAAGCTTTTGCATGGAGGTGTAGCCATCTCTAGC
AAAGGCAGCCCACTGGAGTTGGTTAATGGGGATGGTGTGGACAATGAGATCCGTTGCCTAGATG
ATCCACCTACCGAGATCAGGGAGGAAGAAGATGAGATGGAGCCTGGTGTGGTCTCTGGCACAGC
CAAAGGAACAAGAAGAAGACGACAGAACAACTCAGCCAAACAGTCTTGGCTCCTGAGGCTGTTT
GAATCAAAACTATTTGACATCTCTATGGCCATTTCATACTTGTATAACTCCAAGGAGCCGGGAG
TGCAAGCCTACATTGGCAACCGGCTCTTCTGCTTTCGCAATGAGGATGTGGACTTCTATTTGCC
CCAGTTGCTTAACATGTATATCCATATGGATGAGGATGTGGGTGATGCCATTAAACCCTACATA
GTCCACCGTTGTCGCCAGAGCATCAACTTTTCCCTCCAGTGTGCCCTGTTGCTTGGGGCCTACT
CTTCAGACATGCACATTTCCACTCAACGACACTCCCGAGGGACCAAGTTACGGAAGCTAATCCT
CTCAGATGAGCTGAAGCCAGCTCACCGAAAGAGGGAGCTGCCAACTTTAAGCCCAGCCCCTGAC
ACAGGACTGTCTCCCTCTAAAAGGACTCACCAGCGCTCTAAGTCAGATGCCACGGCCAGCATAA
GTCTCAGCAGCAACCTGAAACGAACAGCCAGCAACCCTAAAGTGGAGAATGAGGATGAGGAGCT
CTCCTCCAGCACCGAGAGTATTGATAATTCATTCAGTTCCCCTGTCCGGCTGGCCCCTGAGCGA
GAATTCATCAAGTCCTTGATGGCAATCGGCAAACGGCTGGCCACGCTCCCCACTAAAGAGCAAA
AAACACAAAGGCTGATCTCAGAACTTTCCCTGCTCAACCATAAGCTCCCTGCCCGAGTCTGGCT
GCCCACAGCTGGCTTTGACCACCACGTGGTCCGTGTGCCCCACACACAAGCTGTTGTCCTCAAT
TCCAAGGATAAGGCTCCCTACCTGATCTATGTGGAAGTTCTTGAATGTGAAAACTTCGACACAA
CTAATGTTCCTGCCCGGATTCCTGAAAACCGAATTCGGAGTACGAGGTCTGTGGAGAACCTGCC
GGAATGTGGTATCACTCACGAGCAGCGGGCTGGCAGCTTCAGCACTGTGCCCAATTATGACAAT
GACGATGAAGCCTGGTCGGTGGATGACATAGGCGAGCTGCAGGTGGAGCTCCCAGAAGTGCACA
CCAACAGCTGTGACAACATCTCTCAGTTCTCGGTGGACAGCATCACCAGCCAGGAGAGCAAGGA
GCCTGTGTTCATTGCGGCAGGGGACATCAGACGGCGCCTTTCAGAACAGCTGGCTCACACTCCC
ACAGCCTTCAAACGAGACCCTGAAGACCCTTCTGCAGTCGCCCTCAAAGAGCCCTGGCAGGAGA
AAGTGCGGAGGATCAGAGAAGGTTCCCCGTATGGCCATCTTCCCAATTGGCGACTCCTTTCAGT
CATTGTCAAGTGTGGAGATGACCTTCGCCAGGAGCTGCTGGCTTTCCAGGTGTTGAAACAACTG
CAGTCCATTTGGGAACAGGAGCGAGTGCCTCTTTGGATCAAGCCATATAAGATTCTTGTGATTT
CAGCTGACAGTGGCATGATTGAACCAGTAGTCAACGCTGTGTCCATCCACCAGGTGAAGAAACA
GTCACAGCTCTCCTTGCTCGATTACTTCCTGCAGGAGCATGGCAGTTACACCACTGAGGCATTC
CTCAGTGCCCAGCGCAATTTTGTGCAAAGTTGTGCTGGCTACTGCTTGGTCTGCTACCTATTAC
AAGTCAAGGACAGGCACAATGGGAACATCCTTCTGGACGCAGAAGGTCACATCATCCACATCGA
CTTTGGCTTCATCCTTTCCAGCTCACCCCGAAACCTGGGCTTCGAGACGTCAGCCTTTAAGCTG
ACCACAGAATTTGTGGATGTAATGGGCGGCCTGAACGGTGATATGTTCAACTACTATAAGATGC
TCATGCTGCAAGGGCTGATCGCTGCTCGCAAACACATGGACAAGGTGGTACAGATTGTGGAGAT
CATGCAGCAAGGTTCTCAGCTTCCTTGCTTCCATGGCTCCAGCACCATTCGCAACCTCAAAGAG
AGGTTCCACATGAGCATGACTGAGGAGCAGCTGCAGCTGCTGGTGGAGCAGATGGTGGACGGCA
GCATGAGGTCCATCACCACCAAACTCTACGATGGCTTCCAGTACCTCACCAATGGCATCATGTG
ACACCACTTTCAGGCCCAGAAGTGGTGGGATTGAAGGCACCCTCCTTAGGAGGACCCTTGCCTA
AGAAAACCTAAATCACAAAATCCCACCTACCTAACCACCTACCCAAGGGAAATGGAAGGCAAAA
AACACAAAGGATCATGTGGTAACCATGAGAGCTGGCCAAAGGGTAGGAGAGCCAACCATGGGGT
CCAGACTTGCTGGGGCTTCCCCACCTCTTGCTGTGTCAGTATTGCCACCTGACAGATCCCAGGA
CTCACTGCCCTCCAGAGAACAGAGATGATGAACATGAGGAGGACTGGAACCTTCTTCCCCTCGG
GGATCTCATCTTTTACTATCCCTGGGTCCCAGCAAGATGGGAGGAGTGGGTTCTTGGTACTTAG
GACTT

hide sequence

RefSeq Acc Id:

XM_008761333 ⟹ XP_008759555

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,591 - 185,261,697 (+)	NCBI
mRatBN7.2	2	182,540,576 - 182,572,684 (+)	NCBI
Rnor_6.0	2	196,139,724 - 196,172,055 (+)	NCBI

Sequence:

show sequence

GGCATGACTCGGGCAGCTCACCCGACTCAGATTACTATGGCATCGGTAGTGTCCTGACAGTTCG
GAAAGCAGGAAAGCAAGCGCCGAGAAGAAAGGCTCGGGCCCAGCGGACTCTTACATCGCAACCC
ATCAAGGAATTGTTATTTTGGGTCCTGCAAGTGGGGTCCGGTCCAACTTGAGGTAGCGTGAAGG
CCCCTTCAGGCGGCGCCGCGGGCAGCCCCGCAGCCGGGGCCTGGTGCAGCCGCCGCGGCCGCTG
TCAGGGAAGCGCAGGCGGCCAATGGAACCCGGGAGCGGCCGCTGCTGCTGAGGCGGCGGTGTCG
GCAGTCCGACCCCGACCGCCTGCACCCCCTCCGCGAGGGTCCCCCGGAGGATGGTGCTCAAGCC
ACCAAACTTGCACACACGGCAAGTGCTCCTACCCACTGAGCCTCCCTCACCTGTCCTATGCCCA
GCTTTCTGCACCTGTTGATGTCATCTGGTTTCTCGAACAGCTTGGAAGCTCGAAGTCTGGCTGT
AGCCATGGGAGACATGGTAGTGGAGCCTGCCACCCTGAAGCCAACTTCTGAGCCTACTCCTAGC
CCATCAGGGAATAACGGGGGCTCCCTACTAAGCGTCATCACGGAGGGGGTCGGGGAACTGTCAG
TGATTGACCCTGAGGTGGCCCAGAAGGCCTGCCAGGAGGTACTGGAGAAAGTCAAGCTTTTGCA
TGGAGGTGTAGCCATCTCTAGCAAAGGCAGCCCACTGGAGTTGGTTAATGGGGATGGTGTGGAC
AATGAGATCCGTTGCCTAGATGATCCACCTACCGAGATCAGGGAGGAAGAAGATGAGATGGAGC
CTGGTGTGGTCTCTGGCACAGCCAAAGGAACAAGAAGAAGACGACAGAACAACTCAGCCAAACA
GTCTTGGCTCCTGAGGCTGTTTGAATCAAAACTATTTGACATCTCTATGGCCATTTCATACTTG
TATAACTCCAAGGAGCCGGGAGTGCAAGCCTACATTGGCAACCGGCTCTTCTGCTTTCGCAATG
AGGATGTGGACTTCTATTTGCCCCAGTTGCTTAACATGTATATCCATATGGATGAGGATGTGGG
TGATGCCATTAAACCCTACATAGTCCACCGTTGTCGCCAGAGCATCAACTTTTCCCTCCAGTGT
GCCCTGTTGCTTGGGGCCTACTCTTCAGACATGCACATTTCTACTCAACGACACTCCCGAGGGA
CCAAGTTACGGAAGCTAATCCTCTCAGATGAGCTGAAGCCAGCTCACCGAAAGAGGGAGCTGCC
AACTTTAAGCCCAGCCCCTGACACAGGACTGTCTCCCTCTAAAAGGACTCACCAGCGCTCTAAG
TCAGATGCCACGGCCAGCATAAGTCTCAGCAGCAACCTGAAACGAACAGCCAGCAACCCTAAAG
TGGAGAATGAGGATGAGGAGCTCTCCTCCAGCACCGAGAGTATTGATAATTCATTCAGTTCCCC
TGTCCGGCTGGCCCCTGAGCGAGAATTCATCAAGTCCTTGATGGCAATCGGCAAACGGCTGGCC
ACGCTCCCCACTAAAGAGCAAAAAACACAAAGGCTGATCTCAGAACTTTCCCTGCTCAACCATA
AGCTCCCTGCCCGAGTCTGGCTGCCCACAGCTGGCTTTGACCACCACGTGGTCCGTGTGCCCCA
CACACAAGCTGTTGTCCTCAATTCCAAGGATAAGGCTCCCTACCTGATCTATGTGGAAGTTCTT
GAATGTGAAAACTTCGACACAACTAATGTTCCTGCCCGGATTCCTGAAAACCGAATTCGGAGTA
CGAGGTCTGTGGAGAACCTGCCGGAATGTGGTATCACTCACGAGCAGCGGGCTGGCAGCTTCAG
CACTGTGCCCAATTATGACAATGACGATGAAGCCTGGTCGGTGGATGACATAGGCGAGCTGCAG
GTGGAGCTCCCAGAAGTGCACACCAACAGCTGTGACAACATCTCTCAGTTCTCGGTGGACAGCA
TCACCAGCCAGGAGAGCAAGGAGCCTGTGTTCATTGCGGCAGGGGACATCAGACGGCGCCTTTC
AGAACAGCTGGCTCACACTCCCACAGCCTTCAAACGAGACCCTGAAGACCCTTCTGCAGTCGCC
CTCAAAGAGCCCTGGCAGGAGAAAGTGCGGAGGATCAGAGAAGGTTCCCCGTATGGCCATCTTC
CCAATTGGCGACTCCTTTCAGTCATTGTCAAGTGTGGAGATGACCTTCGCCAGGAGCTGCTGGC
TTTCCAGGTGTTGAAACAACTGCAGTCCATTTGGGAACAGGAGCGAGTGCCTCTTTGGATCAAG
CCATATAAGATTCTTGTGATTTCAGCTGACAGTGGCATGATTGAACCAGTAGTCAACGCTGTGT
CCATCCACCAGGTGAAGAAACAGTCACAGCTCTCCTTGCTCGATTACTTCCTGCAGGAGCATGG
CAGTTACACCACTGAGGCATTCCTCAGTGCCCAGCGCAATTTTGTGCAAAGTTGTGCTGGCTAC
TGCTTGGTCTGCTACCTATTACAAGTCAAGGACAGGCACAATGGGAACATCCTTCTGGACGCAG
AAGGTCACATCATCCACATCGACTTTGGCTTCATCCTTTCCAGCTCACCCCGAAACCTGGGCTT
CGAGACGTCAGCCTTTAAGCTGACCACAGAATTTGTGGATGTAATGGGCGGCCTGAACGGTGAT
ATGTTCAACTACTATAAGATGCTCATGCTGCAAGGGCTGATCGCTGCTCGCAAACACATGGACA
AGGTGGTACAGATTGTGGAGATCATGCAGCAAGGTTCTCAGCTTCCTTGCTTCCATGGCTCCAG
CACCATTCGCAACCTCAAAGAGAGGTTCCACATGAGCATGACTGAGGAGCAGCTGCAGCTGCTG
GTGGAGCAGATGGTGGACGGCAGCATGAGGTCCATCACCACCAAACTCTACGATGGCTTCCAGT
ACCTCACCAATGGCATCATGTGACACCACTTTCAGGCCCAGAAGTGGTGGGATTGAAGGCACCC
TCCTTAGGAGGACCCTTGCCTAAGAAAACCTAAATCACAAAATCCCACCTACCTAACCACCTAC
CCAAGGGAAATGGAAGGCAAAAAACACAAAGGATCATGTGGTAACCATGAGAGCTGGCCAAAGG
GTAGGAGAGCCAACCATGGGGTCCAGACTTGCTGGGGCTTCCCCACCTCTTGCTGTGTCAGTAT
TGCCACCTGACAGATCCCAGGACTCACTGCCCTCCAGAGAACAGAGATGATGAACATGAGGAGG
ACTGGAACCTTCTTCCCCTCGGGGATCTCAGAGGTTTTCTACAAAACCATCTTTTACTTTCCCT
GGGTCCCAGCAAGATGGGAGGAGTGGGTTCTTGGTACTTAGGACTTAATCCTATGTTTGGCCAT
GCTGCTGCCCAACTCTGTCCCCATCTGGGGGCTGACCCCTAGCCCACATTCCCGACAGGTGGGT
CCTGCACTTGCTTAGGTTCCCCATCATGGGGGTAAGGAAGGGAACTGACACGATCCCTCTAATA
TATTGAGGGTATTGGCTTAGCCATGGGGAAATTTCTCACCCTGATCCTTTCCTCACACCCAGGG
AAATAGCTCTCATTTTTTTTTTTTAATTTTTAATTTTTGTTTGAAATAAAGTCCTTAGTTAGC

hide sequence

RefSeq Acc Id:

XM_039103230 ⟹ XP_038959158

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,591 - 185,261,697 (+)	NCBI
mRatBN7.2	2	182,540,576 - 182,572,684 (+)	NCBI

RefSeq Acc Id:

XM_039103231 ⟹ XP_038959159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,592 - 185,261,697 (+)	NCBI
mRatBN7.2	2	182,540,576 - 182,572,684 (+)	NCBI

RefSeq Acc Id:

XM_039103232 ⟹ XP_038959160

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,592 - 185,261,697 (+)	NCBI
mRatBN7.2	2	182,540,576 - 182,572,684 (+)	NCBI

RefSeq Acc Id:

XM_039103233 ⟹ XP_038959161

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,591 - 185,261,697 (+)	NCBI
mRatBN7.2	2	182,540,576 - 182,572,684 (+)	NCBI

RefSeq Acc Id:

XM_039103234 ⟹ XP_038959162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,691 - 185,261,697 (+)	NCBI
mRatBN7.2	2	182,540,575 - 182,572,684 (+)	NCBI

RefSeq Acc Id:

XM_039103235 ⟹ XP_038959163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,591 - 185,261,697 (+)	NCBI
mRatBN7.2	2	182,540,576 - 182,572,684 (+)	NCBI

RefSeq Acc Id:

XM_063282632 ⟹ XP_063138702

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,229,592 - 185,261,697 (+)	NCBI

RefSeq Acc Id:

XM_063282633 ⟹ XP_063138703

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	185,239,717 - 185,261,697 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001426575	(Get FASTA)	NCBI Sequence Viewer
	NP_112345	(Get FASTA)	NCBI Sequence Viewer
	XP_008759555	(Get FASTA)	NCBI Sequence Viewer
	XP_038959158	(Get FASTA)	NCBI Sequence Viewer
	XP_038959159	(Get FASTA)	NCBI Sequence Viewer
	XP_038959160	(Get FASTA)	NCBI Sequence Viewer
	XP_038959161	(Get FASTA)	NCBI Sequence Viewer
	XP_038959162	(Get FASTA)	NCBI Sequence Viewer
	XP_038959163	(Get FASTA)	NCBI Sequence Viewer
	XP_063138702	(Get FASTA)	NCBI Sequence Viewer
	XP_063138703	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA18969	(Get FASTA)	NCBI Sequence Viewer
	EDL85763	(Get FASTA)	NCBI Sequence Viewer
	EDL85764	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000039342
	ENSRNOP00000082231
	ENSRNOP00000089657
	ENSRNOP00000093461
	ENSRNOP00000095998
GenBank Protein	O08561	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_112345 ⟸ NM_031083

- UniProtKB:

O08561 (UniProtKB/Swiss-Prot), A6K2T7 (UniProtKB/TrEMBL), A0A8L2QJX4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGDMVVEPATLKPTSEPTPSPSGNNGGSLLSVITEGVGELSVIDPEVAQKACQEVLEKVKLLHG
GVAISSKGSPLELVNGDGVDNEIRCLDDPPTEIREEEDEMEPGVVSGTAKGTRRRRQNNSAKQS
WLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCFRNEDVDFYLPQLLNMYIHMDEDVGD
AIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHSRGTKLRKLILSDELKPAHRKRELPT
LSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASNPKVENEDEELSSSTESIDNSFSSPV
RLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHT
QAVVLNSKDKAPYLIYVEVLECENFDTTNVPARIPENRIRSTRSVENLPECGITHEQRAGSFST
VPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSVDSITSQESKEPVFIAAGDIRRRLSE
QLAHTPTAFKRDPEDPSAVALKEPWQEKVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAF
QVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGS
YTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSPRNLGFE
TSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSST
IRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGIM

hide sequence

RefSeq Acc Id:	XP_008759555 ⟸ XM_008761333
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6ALD3 (UniProtKB/TrEMBL), A0A8L2QJX4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPSFLHLLMSSGFSNSLEARSLAVAMGDMVVEPATLKPTSEPTPSPSGNNGGSLLSVITEGVGE LSVIDPEVAQKACQEVLEKVKLLHGGVAISSKGSPLELVNGDGVDNEIRCLDDPPTEIREEEDE MEPGVVSGTAKGTRRRRQNNSAKQSWLLRLFESKLFDISMAISYLYNSKEPGVQAYIGNRLFCF RNEDVDFYLPQLLNMYIHMDEDVGDAIKPYIVHRCRQSINFSLQCALLLGAYSSDMHISTQRHS RGTKLRKLILSDELKPAHRKRELPTLSPAPDTGLSPSKRTHQRSKSDATASISLSSNLKRTASN PKVENEDEELSSSTESIDNSFSSPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLL NHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTNVPARIPENRI RSTRSVENLPECGITHEQRAGSFSTVPNYDNDDEAWSVDDIGELQVELPEVHTNSCDNISQFSV DSITSQESKEPVFIAAGDIRRRLSEQLAHTPTAFKRDPEDPSAVALKEPWQEKVRRIREGSPYG HLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYKILVISADSGMIEPVVN AVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILL DAEGHIIHIDFGFILSSSPRNLGFETSAFKLTTEFVDVMGGLNGDMFNYYKMLMLQGLIAARKH MDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFHMSMTEEQLQLLVEQMVDGSMRSITTKLYDG FQYLTNGIM hide sequence

Ensembl Acc Id:

ENSRNOP00000070653 ⟸ ENSRNOT00000080966

Ensembl Acc Id:

ENSRNOP00000039342 ⟸ ENSRNOT00000040501

RefSeq Acc Id:	XP_038959162 ⟸ XM_039103234
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038959159 ⟸ XM_039103231
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QJX4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959160 ⟸ XM_039103232
- Peptide Label:	isoform X2
- UniProtKB:	A0A8L2QJX4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959158 ⟸ XM_039103230
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QJX4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959161 ⟸ XM_039103233
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2JYH1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038959163 ⟸ XM_039103235
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I5ZT79 (UniProtKB/TrEMBL), A0A8L2QJX4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095998 ⟸ ENSRNOT00000112486

Ensembl Acc Id:

ENSRNOP00000093461 ⟸ ENSRNOT00000112810

Ensembl Acc Id:

ENSRNOP00000089657 ⟸ ENSRNOT00000118319

Ensembl Acc Id:

ENSRNOP00000082231 ⟸ ENSRNOT00000103639

RefSeq Acc Id:	XP_063138702 ⟸ XM_063282632
- Peptide Label:	isoform X7
- UniProtKB:	A0A8L2QJX4 (UniProtKB/TrEMBL), A0A8I6ASK5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138703 ⟸ XM_063282633
- Peptide Label:	isoform X8

Protein Domains

PI3K/PI4K catalytic PIK helical

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O08561-F1-model_v2	AlphaFold	O08561	1-816	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691534

Promoter ID:

EPDNEW_R2059

Type:

initiation region

Name:

Pi4kb_1

Description:

phosphatidylinositol 4-kinase beta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R2060

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	196,139,717 - 196,139,777	EPDNEW

RGD ID:

13691535

Promoter ID:

EPDNEW_R2060

Type:

initiation region

Name:

Pi4kb_2

Description:

phosphatidylinositol 4-kinase beta

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R2059

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	196,139,963 - 196,140,023	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621214	AgrOrtholog
BioCyc Gene	G2FUF-52130	BioCyc
BioCyc Pathway	PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis]	BioCyc
	PWY-6352 [3-phosphoinositide biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-6351	BioCyc
	PWY-6352	BioCyc
Ensembl Genes	ENSRNOG00000021024	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000040501	ENTREZGENE
	ENSRNOT00000103639	ENTREZGENE
	ENSRNOT00000112486	ENTREZGENE
	ENSRNOT00000112810	ENTREZGENE
	ENSRNOT00000118319	ENTREZGENE
Gene3D-CATH	1.10.1070.11	UniProtKB/Swiss-Prot
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4	UniProtKB/Swiss-Prot
InterPro	Kinase-like_dom	UniProtKB/Swiss-Prot
	PI3/4_kinase_cat	UniProtKB/Swiss-Prot
	PI3/4_kinase_cat_sf	UniProtKB/Swiss-Prot
	PI3/4_kinase_CS	UniProtKB/Swiss-Prot
	PI4KB-PIK1_PIK	UniProtKB/Swiss-Prot
	PI_Kinase	UniProtKB/Swiss-Prot
	PInositide-3_kin_accessory_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:81747	UniProtKB/Swiss-Prot
NCBI Gene	81747	ENTREZGENE
PANTHER	PHOSPHATIDYLINOSITOL 4-KINASE BETA	UniProtKB/Swiss-Prot
	PI_Kinase	UniProtKB/Swiss-Prot
Pfam	PI3_PI4_kinase	UniProtKB/Swiss-Prot
	PI4KB-PIK1_PIK	UniProtKB/Swiss-Prot
PhenoGen	Pi4kb	PhenoGen
PROSITE	PI3_4_KINASE_1	UniProtKB/Swiss-Prot
	PI3_4_KINASE_2	UniProtKB/Swiss-Prot
	PI3_4_KINASE_3	UniProtKB/Swiss-Prot
	PIK_HELICAL	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000021024	RatGTEx
SMART	PI3Kc	UniProtKB/Swiss-Prot
Superfamily-SCOP	Kinase_like	UniProtKB/Swiss-Prot
UniProt	A0A0G2JYH1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZT79	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AD21	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ALD3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ASK5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QJX4	ENTREZGENE, UniProtKB/TrEMBL
	A6K2T7	ENTREZGENE, UniProtKB/TrEMBL
	O08561	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-01	Pi4kb	phosphatidylinositol 4-kinase beta	Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-19	Pi4kb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	Pik4cb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Pik4cb	phosphatidylinositol 4-kinase, catalytic, beta polypeptide		phosphatidylinositol 4-kinase	Name updated	1299863	APPROVED
2002-08-07	Pik4cb	phosphatidylinositol 4-kinase			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	dispersed in the cytoplasm	633727
gene_expression	expressed ubiquitously; present throughout the grey matter of the brain; enriched in fetal brain	633727
gene_protein	816 amino acids; 91.6 kDa	633727

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

BioCyc Pathways