Pi4kb (phosphatidylinositol 4-kinase beta) - Rat Genome Database

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Gene: Pi4kb (phosphatidylinositol 4-kinase beta) Ictidomys tridecemlineatus
Analyze
Symbol: Pi4kb
Name: phosphatidylinositol 4-kinase beta
RGD ID: 12722096
Description: ENCODES a protein that exhibits 1-phosphatidylinositol 4-kinase activity (ortholog); INVOLVED IN lysosome organization (ortholog); ASSOCIATED WITH Autosomal Dominant Nonsyndromic Deafness 87 (ortholog); Coronavirus infectious disease (ortholog); Dravet syndrome (ortholog); FOUND IN cytoplasm (inferred); endomembrane system (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol 4-kinase beta, transcript variant X1; phosphatidylinositol 4-kinase beta, transcript variant X2; phosphatidylinositol 4-kinase beta, transcript variant X3; phosphatidylinositol 4-kinase beta, transcript variant X4; phosphatidylinositol 4-kinase beta, transcript variant X5; phosphatidylinositol 4-kinase beta, transcript variant X6; phosphatidylinositol 4-kinase beta, transcript variant X7; phosphatidylinositol 4-kinase beta, transcript variant X8; phosphatidylinositol 4-kinase beta, transcript variant X9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,465,447 - 22,493,491 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,495,833 - 1,523,276 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,495,833 - 1,523,307 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Pi4kb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,465,447 - 22,493,491 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365801,495,833 - 1,523,276 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365801,495,833 - 1,523,307 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PI4KB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,291,797 - 151,327,715 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1151,291,797 - 151,327,715 (-)EnsemblGRCh38hg38GRCh38
GRCh371151,264,273 - 151,300,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,531,037 - 149,565,348 (-)NCBINCBI36Build 36hg18NCBI36
Build 341148,077,485 - 148,111,797NCBI
Celera1124,379,704 - 124,414,015 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1122,642,216 - 122,678,133 (-)NCBIHuRef
CHM1_11152,660,019 - 152,695,935 (-)NCBICHM1_1
T2T-CHM13v2.01150,415,490 - 150,452,405 (-)NCBIT2T-CHM13v2.0
Pi4kb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,882,042 - 94,914,248 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl394,882,042 - 94,914,154 (+)EnsemblGRCm39 Ensembl
GRCm38394,974,731 - 95,006,937 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl394,974,731 - 95,006,843 (+)EnsemblGRCm38mm10GRCm38
MGSCv37394,778,653 - 94,810,765 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,060,140 - 95,091,993 (+)NCBIMGSCv36mm8
Celera396,405,996 - 96,438,094 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.74NCBI
Pi4kb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,229,392 - 185,261,697 (+)NCBIGRCr8
mRatBN7.22182,540,377 - 182,572,684 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2182,540,567 - 182,588,488 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2190,205,165 - 190,237,217 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,000,894 - 188,032,951 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02182,837,647 - 182,869,695 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02196,139,724 - 196,172,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,139,755 - 196,171,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,634,003 - 215,666,743 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,874,613 - 189,906,640 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12189,834,020 - 189,866,048 (+)NCBI
Celera2175,082,416 - 175,114,456 (+)NCBICelera
Cytogenetic Map2q34NCBI
Pi4kb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955588648,180 - 679,374 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955588648,180 - 679,374 (-)NCBIChiLan1.0ChiLan1.0
PI4KB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,492,576 - 98,528,619 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,243,803 - 98,279,850 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01126,653,794 - 126,689,690 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11130,300,844 - 130,336,320 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1130,300,844 - 130,336,311 (-)Ensemblpanpan1.1panPan2
PI4KB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,359,545 - 60,386,093 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,360,236 - 60,384,778 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,803,028 - 59,830,272 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01761,375,750 - 61,403,019 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1761,375,754 - 61,402,452 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11760,203,634 - 60,230,882 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01760,289,810 - 60,317,042 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01761,018,193 - 61,044,694 (-)NCBIUU_Cfam_GSD_1.0
PI4KB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,918,245 - 97,949,931 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,918,234 - 97,949,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,119,069 - 107,150,710 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PI4KB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12012,358,758 - 12,395,372 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2012,358,762 - 12,394,661 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603811,933,446 - 11,970,304 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pi4kb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,532,986 - 18,564,492 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,533,603 - 18,564,160 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000013237   ⟹   ENSSTOP00000011863
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365801,495,835 - 1,523,275 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000032253   ⟹   ENSSTOP00000032323
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365801,495,835 - 1,523,276 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000039330   ⟹   ENSSTOP00000025700
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365801,495,833 - 1,523,274 (-)Ensembl
RefSeq Acc Id: XM_013361153   ⟹   XP_013216607
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,995 - 22,493,347 (-)NCBI
SpeTri2.0NW_0049365801,495,835 - 1,523,298 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013361155   ⟹   XP_013216609
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,466,151 - 22,493,491 (-)NCBI
SpeTri2.0NW_0049365801,495,835 - 1,523,298 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013361156   ⟹   XP_013216610
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,995 - 22,493,342 (-)NCBI
SpeTri2.0NW_0049365801,495,835 - 1,523,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013361157   ⟹   XP_013216611
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,453 - 22,493,338 (-)NCBI
SpeTri2.0NW_0049365801,495,835 - 1,523,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013361158   ⟹   XP_013216612
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,453 - 22,493,336 (-)NCBI
SpeTri2.0NW_0049365801,495,835 - 1,523,294 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021730444   ⟹   XP_021586119
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,447 - 22,492,930 (-)NCBI
SpeTri2.0NW_0049365801,495,835 - 1,523,299 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021730446   ⟹   XP_021586121
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,447 - 22,493,337 (-)NCBI
SpeTri2.0NW_0049365801,495,833 - 1,523,307 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021730447   ⟹   XP_021586122
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,447 - 22,493,329 (-)NCBI
SpeTri2.0NW_0049365801,495,835 - 1,523,291 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040287564   ⟹   XP_040143498
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,466,151 - 22,486,182 (-)NCBI
RefSeq Acc Id: XM_040287566   ⟹   XP_040143500
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505822,465,447 - 22,493,341 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013216612   ⟸   XM_013361158
- Peptide Label: isoform X4
- UniProtKB: A0A287CWJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013216609   ⟸   XM_013361155
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013216607   ⟸   XM_013361153
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013216610   ⟸   XM_013361156
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013216611   ⟸   XM_013361157
- Peptide Label: isoform X3
- UniProtKB: I3MKL7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021586121   ⟸   XM_021730446
- Peptide Label: isoform X4
- UniProtKB: A0A287CWJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021586119   ⟸   XM_021730444
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021586122   ⟸   XM_021730447
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_040143500   ⟸   XM_040287566
- Peptide Label: isoform X3
- UniProtKB: I3MKL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143498   ⟸   XM_040287564
- Peptide Label: isoform X1
RefSeq Acc Id: ENSSTOP00000025700   ⟸   ENSSTOT00000039330
RefSeq Acc Id: ENSSTOP00000032323   ⟸   ENSSTOT00000032253
RefSeq Acc Id: ENSSTOP00000011863   ⟸   ENSSTOT00000013237
Protein Domains
PI3K/PI4K catalytic   PIK helical


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013237 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013237.3 UniProtKB/TrEMBL
  ENSSTOT00000032253.1 UniProtKB/TrEMBL
  ENSSTOT00000039330.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1070.11 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  PI3/4_kinase_cat_dom UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/TrEMBL
  PI3K_accessory_dom UniProtKB/TrEMBL
  PI4KB-PIK1_PIK UniProtKB/TrEMBL
  PI_Kinase UniProtKB/TrEMBL
NCBI Gene Pi4kb ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 4-KINASE BETA UniProtKB/TrEMBL
  PTHR10048 UniProtKB/TrEMBL
Pfam PI3_PI4_kinase UniProtKB/TrEMBL
  PI4KB-PIK1_PIK UniProtKB/TrEMBL
PROSITE PI3_4_KINASE_1 UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/TrEMBL
  PIK_HELICAL UniProtKB/TrEMBL
SMART PI3Kc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A287CWJ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DFI8_ICTTR UniProtKB/TrEMBL
  I3MKL7 ENTREZGENE, UniProtKB/TrEMBL