Abi1 (abl-interactor 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Abi1 (abl-interactor 1) Rattus norvegicus
Analyze
Symbol: Abi1
Name: abl-interactor 1
RGD ID: 621008
Description: Predicted to enable SH3 domain binding activity; protein tyrosine kinase activator activity; and signaling adaptor activity. Involved in postsynapse to nucleus signaling pathway. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human ABI1 (abl interactor 1); PARTICIPATES IN E-cadherin signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: abelson interactor 1; abi-1; abl interactor 1; E3b1; eps8 binding protein (e3B1), alternatively spliced; eps8 SH3 domain-binding protein; eps8-binding protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81790,006,917 - 90,088,002 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1790,006,925 - 90,087,827 (-)EnsemblGRCr8
mRatBN7.21785,098,837 - 85,179,829 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1785,098,550 - 85,179,792 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1788,583,073 - 88,664,013 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01792,418,465 - 92,499,400 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01786,435,255 - 86,516,184 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01789,951,662 - 90,033,334 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1789,951,752 - 90,033,328 (+)Ensemblrn6Rnor6.0
Rnor_5.01791,617,052 - 91,698,739 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41796,576,331 - 96,648,752 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1783,715,811 - 83,796,579 (+)NCBICelera
RGSC_v3.11796,587,163 - 96,659,522 (-)NCBI
Cytogenetic Map17q12.3NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-fluorouracil  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bortezomib  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carnosic acid  (ISO)
chloroprene  (EXP)
chlorpyrifos  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
deoxynivalenol  (ISO)
dextran sulfate  (ISO)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (ISO)
doxorubicin  (ISO)
erianin  (ISO)
ethanol  (ISO)
finasteride  (EXP)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gallic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen cyanide  (ISO)
ivermectin  (ISO)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
palytoxin  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
potassium cyanide  (ISO)
resveratrol  (EXP,ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sulindac  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
actin-based cell projection  (IBA)
cell leading edge  (IEA,ISO)
cytoplasm  (IEA)
cytoskeleton  (IEA)
filopodium  (IEA)
filopodium tip  (ISO)
glutamatergic synapse  (EXP,IDA,IEP,IMP)
growth cone  (IEA)
lamellipodium  (IBA,IEA,ISO)
neuron projection  (IEA,ISO)
nucleus  (IEA)
postsynaptic density  (IDA,IEA,IEP,IMP)
SCAR complex  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion. Chazeau A, etal., EMBO J. 2014 Dec 1;33(23):2745-64. doi: 10.15252/embj.201488837. Epub 2014 Oct 7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation. Ito H, etal., Mol Psychiatry. 2010 Oct;15(10):976-86. doi: 10.1038/mp.2010.69. Epub 2010 Jun 8.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. Proepper C, etal., EMBO J. 2007 Mar 7;26(5):1397-409. Epub 2007 Feb 15.
8. Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphology. Proepper C, etal., PLoS One. 2011;6(11):e27045. doi: 10.1371/journal.pone.0027045. Epub 2011 Nov 15.
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton. Ziemnicka-Kotula D, etal., J Biol Chem 1998 May 29;273(22):13681-92.
Additional References at PubMed
PMID:10995551   PMID:11516653   PMID:12477932   PMID:12672821   PMID:15755804   PMID:16831833   PMID:17101133   PMID:17664349   PMID:18560548   PMID:19056867   PMID:19200726   PMID:19798448  
PMID:21107423   PMID:21464958   PMID:21795692   PMID:25297099   PMID:25468996   PMID:28131823   PMID:30053369  


Genomics

Comparative Map Data
Abi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81790,006,917 - 90,088,002 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1790,006,925 - 90,087,827 (-)EnsemblGRCr8
mRatBN7.21785,098,837 - 85,179,829 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1785,098,550 - 85,179,792 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1788,583,073 - 88,664,013 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01792,418,465 - 92,499,400 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01786,435,255 - 86,516,184 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01789,951,662 - 90,033,334 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1789,951,752 - 90,033,328 (+)Ensemblrn6Rnor6.0
Rnor_5.01791,617,052 - 91,698,739 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41796,576,331 - 96,648,752 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1783,715,811 - 83,796,579 (+)NCBICelera
RGSC_v3.11796,587,163 - 96,659,522 (-)NCBI
Cytogenetic Map17q12.3NCBI
ABI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381026,746,596 - 26,860,958 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1026,745,942 - 26,861,094 (-)Ensemblhg38GRCh38
GRCh371027,035,525 - 27,149,887 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361027,075,531 - 27,189,965 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1026,743,902 - 26,858,351 (-)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1026,695,811 - 26,810,376 (-)NCBIHuRef
CHM1_11027,032,979 - 27,149,984 (-)NCBICHM1_1
T2T-CHM13v2.01026,768,504 - 26,882,882 (-)NCBIT2T-CHM13v2.0
Abi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39222,830,085 - 22,930,207 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl222,830,085 - 22,930,253 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38222,940,073 - 23,040,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl222,940,073 - 23,040,241 (-)Ensemblmm10GRCm38
MGSCv37222,795,509 - 22,895,760 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36222,772,161 - 22,862,244 (-)NCBIMGSCv36mm8
Celera222,671,348 - 22,771,879 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map215.18NCBI
Abi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554292,682,343 - 2,783,752 (+)Ensembl
ChiLan1.0NW_0049554292,682,341 - 2,783,752 (+)NCBIChiLan1.0ChiLan1.0
ABI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2839,383,822 - 39,495,774 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11039,389,108 - 39,501,098 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01026,863,648 - 26,975,376 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11027,227,960 - 27,339,434 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1027,227,960 - 27,339,434 (-)EnsemblpanPan2panpan1.1
ABI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.126,941,752 - 7,059,466 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl26,941,900 - 7,057,684 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha25,695,050 - 5,812,623 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.025,131,485 - 5,249,349 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl25,131,464 - 5,249,349 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.124,508,861 - 4,626,433 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.024,587,702 - 4,705,303 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.024,752,811 - 4,870,263 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Abi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934425,925,448 - 26,028,891 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364842,088,927 - 2,194,109 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364842,090,605 - 2,194,109 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,939,446 - 49,069,441 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11048,939,407 - 49,069,269 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ABI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1926,377,822 - 26,495,665 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl926,379,516 - 26,495,676 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605132,373,606 - 32,493,129 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247962,312,005 - 2,431,284 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Abi1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1141,547,249 - 1,625,829 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:224
Count of miRNA genes:145
Interacting mature miRNAs:188
Transcripts:ENSRNOT00000057572
Prediction methods:Miranda, Pita, Pita,Targetscan, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat

Markers in Region
D17Rat51  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21785,119,450 - 85,119,583 (-)MAPPERmRatBN7.2
Rnor_6.01790,012,592 - 90,012,722NCBIRnor6.0
Rnor_5.01791,677,997 - 91,678,127UniSTSRnor5.0
RGSC_v3.41796,587,775 - 96,587,905UniSTSRGSC3.4
RGSC_v3.41796,587,774 - 96,587,905RGDRGSC3.4
Celera1783,775,845 - 83,775,971UniSTS
RGSC_v3.11796,598,608 - 96,598,738RGD
RH 3.4 Map17848.7RGD
RH 3.4 Map17848.7UniSTS
RH 2.0 Map17730.2RGD
SHRSP x BN Map1747.5399RGD
FHH x ACI Map1768.73RGD
Cytogenetic Map17q12.3UniSTS
RH127345  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21785,099,165 - 85,099,348 (-)MAPPERmRatBN7.2
Rnor_6.01790,032,823 - 90,033,005NCBIRnor6.0
Rnor_5.01791,698,228 - 91,698,410UniSTSRnor5.0
Celera1783,796,068 - 83,796,250UniSTS
RH 3.4 Map17841.2UniSTS
Cytogenetic Map17q12.3UniSTS
RH137994  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21785,176,056 - 85,176,305 (-)MAPPERmRatBN7.2
Rnor_6.01789,955,200 - 89,955,448NCBIRnor6.0
Rnor_5.01791,620,605 - 91,620,853UniSTSRnor5.0
RGSC_v3.41796,645,056 - 96,645,304UniSTSRGSC3.4
Celera1783,719,259 - 83,719,507UniSTS
RH 3.4 Map17863.7UniSTS
Cytogenetic Map17q12.3UniSTS
AI009242  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21785,145,642 - 85,145,846 (-)MAPPERmRatBN7.2
Rnor_6.01789,986,322 - 89,986,525NCBIRnor6.0
Rnor_5.01791,651,727 - 91,651,930UniSTSRnor5.0
RGSC_v3.41796,614,187 - 96,614,390UniSTSRGSC3.4
Celera1783,749,643 - 83,749,846UniSTS
RH 3.4 Map17844.3UniSTS
Cytogenetic Map17q12.3UniSTS
AU049482  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21785,171,263 - 85,171,421 (-)MAPPERmRatBN7.2
Rnor_6.01789,960,404 - 89,960,561NCBIRnor6.0
Rnor_5.01791,625,809 - 91,625,966UniSTSRnor5.0
RGSC_v3.41796,639,806 - 96,639,963UniSTSRGSC3.4
Celera1783,724,076 - 83,724,236UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF176784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB725283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000057572   ⟹   ENSRNOP00000054381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1790,006,925 - 90,087,827 (-)Ensembl
mRatBN7.2 Ensembl1785,098,845 - 85,179,753 (-)Ensembl
Rnor_6.0 Ensembl1789,951,752 - 90,033,328 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091023   ⟹   ENSRNOP00000071079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1790,008,065 - 90,087,764 (-)Ensembl
mRatBN7.2 Ensembl1785,098,550 - 85,179,777 (-)Ensembl
Rnor_6.0 Ensembl1789,951,815 - 90,032,186 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093928   ⟹   ENSRNOP00000081022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1790,006,925 - 90,087,827 (-)Ensembl
mRatBN7.2 Ensembl1785,098,852 - 85,179,792 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103736   ⟹   ENSRNOP00000085236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1790,006,925 - 90,087,827 (-)Ensembl
mRatBN7.2 Ensembl1785,098,845 - 85,179,753 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108948   ⟹   ENSRNOP00000093871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1790,006,925 - 90,087,827 (-)Ensembl
mRatBN7.2 Ensembl1785,098,555 - 85,179,746 (-)Ensembl
RefSeq Acc Id: NM_024397   ⟹   NP_077373
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,827 (-)NCBI
mRatBN7.21785,098,837 - 85,179,753 (-)NCBI
Rnor_6.01789,951,752 - 90,033,334 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
RGSC_v3.41796,576,331 - 96,648,752 (-)RGD
Celera1783,715,811 - 83,796,579 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254353   ⟹   XP_006254415
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,968 (-)NCBI
mRatBN7.21785,098,837 - 85,179,825 (-)NCBI
Rnor_6.01789,951,681 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254354   ⟹   XP_006254416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,968 (-)NCBI
mRatBN7.21785,098,837 - 85,179,825 (-)NCBI
Rnor_6.01789,951,681 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254355   ⟹   XP_006254417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,968 (-)NCBI
mRatBN7.21785,098,837 - 85,179,825 (-)NCBI
Rnor_6.01789,951,681 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254356   ⟹   XP_006254418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,088,002 (-)NCBI
mRatBN7.21785,098,837 - 85,179,824 (-)NCBI
Rnor_6.01789,951,681 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254357   ⟹   XP_006254419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,977 (-)NCBI
mRatBN7.21785,098,837 - 85,179,825 (-)NCBI
Rnor_6.01789,951,681 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254358   ⟹   XP_006254420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,968 (-)NCBI
mRatBN7.21785,098,837 - 85,179,824 (-)NCBI
Rnor_6.01789,951,682 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254359   ⟹   XP_006254421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,990 (-)NCBI
mRatBN7.21785,098,837 - 85,179,824 (-)NCBI
Rnor_6.01789,951,682 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254360   ⟹   XP_006254422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,087,968 (-)NCBI
mRatBN7.21785,098,837 - 85,179,829 (-)NCBI
Rnor_6.01789,951,662 - 90,033,158 (+)NCBI
Rnor_5.01791,617,052 - 91,698,739 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096101   ⟹   XP_038952029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,088,002 (-)NCBI
mRatBN7.21785,098,837 - 85,179,825 (-)NCBI
RefSeq Acc Id: XM_039096103   ⟹   XP_038952031
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81790,006,917 - 90,079,403 (-)NCBI
mRatBN7.21785,098,837 - 85,158,169 (-)NCBI
RefSeq Acc Id: NP_077373   ⟸   NM_024397
- UniProtKB: A2VD09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254422   ⟸   XM_006254360
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006254418   ⟸   XM_006254356
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006254415   ⟸   XM_006254353
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006254420   ⟸   XM_006254358
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZQS1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254416   ⟸   XM_006254354
- Peptide Label: isoform X2
- UniProtKB: Q9QZM5 (UniProtKB/Swiss-Prot),   A6KRZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254417   ⟸   XM_006254355
- Peptide Label: isoform X3
- UniProtKB: A0A8L2UQ93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254419   ⟸   XM_006254357
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006254421   ⟸   XM_006254359
- Peptide Label: isoform X10
- Sequence:
Ensembl Acc Id: ENSRNOP00000054381   ⟸   ENSRNOT00000057572
Ensembl Acc Id: ENSRNOP00000071079   ⟸   ENSRNOT00000091023
RefSeq Acc Id: XP_038952029   ⟸   XM_039096101
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AGM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952031   ⟸   XM_039096103
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000081022   ⟸   ENSRNOT00000093928
Ensembl Acc Id: ENSRNOP00000093871   ⟸   ENSRNOT00000108948
Ensembl Acc Id: ENSRNOP00000085236   ⟸   ENSRNOT00000103736
Protein Domains
SH3   t-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZM5-F1-model_v2 AlphaFold Q9QZM5 1-476 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700617
Promoter ID:EPDNEW_R11140
Type:initiation region
Name:Abi1_1
Description:abl-interactor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01789,951,725 - 89,951,785EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621008 AgrOrtholog
BioCyc Gene G2FUF-8481 BioCyc
Ensembl Genes ENSRNOG00000031325 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000057572 ENTREZGENE
  ENSRNOT00000091023 ENTREZGENE
  ENSRNOT00000093928 ENTREZGENE
  ENSRNOT00000108948 ENTREZGENE
Gene3D-CATH 6.10.140.1620 UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7192971 IMAGE-MGC_LOAD
InterPro ABI UniProtKB/Swiss-Prot
  Abi1_SH3 UniProtKB/Swiss-Prot
  Abl-interactor_HHR_dom UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
  T_SNARE_dom UniProtKB/Swiss-Prot
MGC_CLONE MGC:156634 IMAGE-MGC_LOAD
NCBI Gene 79249 ENTREZGENE
PANTHER PTHR10460 UniProtKB/Swiss-Prot
  PTHR10460:SF2 UniProtKB/Swiss-Prot
Pfam Abi_HHR UniProtKB/Swiss-Prot
  SH3_1 UniProtKB/Swiss-Prot
PhenoGen Abi1 PhenoGen
PRINTS P67PHOX UniProtKB/Swiss-Prot
  SH3DOMAIN UniProtKB/Swiss-Prot
PROSITE SH3 UniProtKB/Swiss-Prot
  T_SNARE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031325 RatGTEx
SMART SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot
UniProt A0A8I5ZQS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0X0_RAT UniProtKB/TrEMBL
  A0A8I6AGM2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UQ93 ENTREZGENE, UniProtKB/TrEMBL
  A2VD09 ENTREZGENE, UniProtKB/TrEMBL
  A6KRZ5 ENTREZGENE, UniProtKB/TrEMBL
  ABI1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Abi1  abl-interactor 1    eps8 binding protein (e3B1), alternatively spliced  Name updated 1299863 APPROVED
2002-08-07 Abi1  eps8 binding protein (e3B1), alternatively spliced      Symbol and Name status set to provisional 70820 PROVISIONAL