Lin7b (lin-7 homolog B, crumbs cell polarity complex component) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Lin7b (lin-7 homolog B, crumbs cell polarity complex component) Rattus norvegicus
Analyze
Symbol: Lin7b
Name: lin-7 homolog B, crumbs cell polarity complex component
RGD ID: 620730
Description: Enables PDZ domain binding activity and protein kinase binding activity. Predicted to be involved in neurotransmitter secretion; regulation of synaptic assembly at neuromuscular junction; and synaptic vesicle transport. Located in cell-cell junction. Is active in postsynaptic density, intracellular component. Orthologous to human LIN7B (lin-7 homolog B, crumbs cell polarity complex component); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lin 7 homolog b; lin 7 homolog b (C. elegans); lin-7 homolog B (C. elegans); lin-7-A; lin-7B; MALS-2; MALS2; mammalian lin-seven protein 2; protein lin-7 homolog B; veli-2 protein; Veli1a; Veli2; vertebrate homolog of C. elegans Lin-7 type 2; vertebrate lin-7 homolog 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,983,368 - 104,986,795 (-)NCBIGRCr8
mRatBN7.2195,846,888 - 95,849,628 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,846,243 - 95,849,977 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,232,405 - 101,234,980 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,705,082 - 109,707,657 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,995,482 - 102,998,057 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,358,313 - 101,361,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,358,396 - 101,360,971 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,421,965 - 102,425,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,838,781 - 95,841,356 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,916,891 - 95,919,467 (-)NCBI
Celera190,103,272 - 90,105,847 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lin7bRatdevelopmental and epileptic encephalopathy 12  ISOLIN7B (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 12ClinVarPMID:28492532
Lin7bRatprogressive familial heart block type IB  ISOLIN7B (Homo sapiens)8554872ClinVar Annotator: match by term: Progressive familial heart block type IBClinVarPMID:28492532

1 to 20 of 66 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lin7bRat1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactionsISOLin7b (Mus musculus)6480464[2 more ...CTDPMID:25510870
Lin7bRat17alpha-ethynylestradiol affects expressionISOLin7b (Mus musculus)6480464Ethinyl Estradiol affects the expression of LIN7B mRNACTDPMID:17555576
Lin7bRat17alpha-ethynylestradiol multiple interactionsISOLin7b (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LIN7B mRNACTDPMID:17942748
Lin7bRat17alpha-ethynylestradiol increases expressionISOLin7b (Mus musculus)6480464Ethinyl Estradiol results in increased expression of LIN7B mRNACTDPMID:17942748
Lin7bRat17beta-hydroxy-5alpha-androstan-3-one increases expressionISOLIN7B (Homo sapiens)6480464Dihydrotestosterone results in increased expression of LIN7B mRNACTDPMID:29581250
Lin7bRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOLin7b (Mus musculus)6480464[2 more ...CTDPMID:25510870
Lin7bRat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOLin7b (Mus musculus)6480464[2 more ...CTDPMID:25510870
Lin7bRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOLin7b (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LIN7B mRNACTDPMID:17942748
Lin7bRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of LIN7B mRNACTDPMID:32109520
Lin7bRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOLin7b (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of LIN7B mRNACTDPMID:21570461
Lin7bRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOLin7b (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of LIN7B mRNACTDPMID:17942748
Lin7bRat2,4,4'-trichlorobiphenyl multiple interactionsISOLin7b (Mus musculus)6480464[2 more ...CTDPMID:25510870
Lin7bRat2,4-D multiple interactionsISOLin7b (Mus musculus)6480464[lard co-treated with Cholesterol more ...CTDPMID:37567420
Lin7bRat2-hydroxypropanoic acid decreases expressionISOLIN7B (Homo sapiens)6480464Lactic Acid results in decreased expression of LIN7B mRNACTDPMID:30851411
Lin7bRat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of LIN7B mRNACTDPMID:36041667
Lin7bRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of LIN7B mRNACTDPMID:24780913
Lin7bRatacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of LIN7B mRNACTDPMID:28959563
Lin7bRatacrylamide decreases expressionISOLIN7B (Homo sapiens)6480464Acrylamide results in decreased expression of LIN7B mRNACTDPMID:32763439
Lin7bRatacrylamide increases expressionISOLin7b (Mus musculus)6480464Acrylamide results in increased expression of LIN7B mRNACTDPMID:30807115
Lin7bRataldehydo-D-glucose multiple interactionsISOLin7b (Mus musculus)6480464[lard co-treated with Cholesterol more ...CTDPMID:37567420

1 to 20 of 66 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lin7bRatcell-cell junction assembly  NAS 633233 RGD 
Lin7bRatexocytosis involved_inIEAUniProtKB-KW:KW-02681600115GO_REF:0000043UniProtGO_REF:0000043
Lin7bRatneurotransmitter secretion involved_inIBAMGI:1330839 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Lin7bRatneurotransmitter secretion acts_upstream_of_or_withinISOLin7b (Mus musculus)1624291MGI:1330839 more ...RGDPMID:16186258
Lin7bRatprotein transport involved_inIEAUniProtKB-KW:KW-06531600115GO_REF:0000043UniProtGO_REF:0000043
Lin7bRatregulation of synaptic assembly at neuromuscular junction involved_inIBAFB:FBgn0039269 and PANTHER:PTN0010192681600115GO_REF:0000033GO_CentralGO_REF:0000033
Lin7bRatsynaptic vesicle transport involved_inIBAMGI:2135609 and PANTHER:PTN0010192681600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Lin7bRatanchoring junction located_inIEAUniProtKB-KW:KW-09651600115GO_REF:0000043UniProtGO_REF:0000043
Lin7bRatanchoring junction located_inIEAUniProtKB-SubCell:SL-00381600115GO_REF:0000044UniProtGO_REF:0000044
Lin7bRatbasolateral plasma membrane is_active_inIBAMGI:2135609 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Lin7bRatbasolateral plasma membrane located_inIEAUniProtKB-SubCell:SL-00261600115GO_REF:0000044UniProtGO_REF:0000044
Lin7bRatbicellular tight junction located_inIEAUniProtKB-SubCell:SL-02651600115GO_REF:0000044UniProtGO_REF:0000044
Lin7bRatbicellular tight junction located_inIEAUniProtKB-KW:KW-07961600115GO_REF:0000043UniProtGO_REF:0000043
Lin7bRatcell-cell junction is_active_inIBAFB:FBgn0039269 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Lin7bRatcell-cell junction  IDA 633233 RGD 
Lin7bRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Lin7bRatMPP7-DLG1-LIN7 complex part_ofIBAPANTHER:PTN000362480 and UniProtKB:Q9NUP91600115GO_REF:0000033GO_CentralGO_REF:0000033
Lin7bRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Lin7bRatplasma membrane located_inISOLin7b (Mus musculus)1624291 PMID:10341223RGDPMID:10341223
Lin7bRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Lin7bRatplasma membrane located_inTAS 1600115Reactome:R-RNO-6794334ReactomeReactome:R-RNO-6794334
Lin7bRatpostsynaptic density membrane located_inIEAUniProtKB-SubCell:SL-05201600115GO_REF:0000044UniProtGO_REF:0000044
Lin7bRatpostsynaptic density, intracellular component is_active_inIDA 405650264PMID:24753440SynGO 
Lin7bRatpostsynaptic membrane located_inIEAUniProtKB-KW:KW-06281600115GO_REF:0000043UniProtGO_REF:0000043
Lin7bRatpresynapse located_inIEAGO:00072691600115GO_REF:0000108GOCGO_REF:0000108
Lin7bRatsynapse is_active_inIBAFB:FBgn0039269 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Lin7bRatsynapse located_inIEAUniProtKB-KW:KW-07701600115GO_REF:0000043UniProtGO_REF:0000043
1 to 20 of 20 rows

Molecular Function
1 to 9 of 9 rows

  
1 to 9 of 9 rows


1 to 12 of 12 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. CASK associates with glutamate receptor interacting protein and signaling molecules. Hong CJ and Hsueh YP, Biochem Biophys Res Commun. 2006 Dec 22;351(3):771-6. Epub 2006 Oct 30.
4. MALS is a binding partner of IRSp53 at cell-cell contacts. Hori K, etal., FEBS Lett. 2003 Nov 6;554(1-2):30-4.
5. Calcium influx and postsynaptic proteins coordinate the dendritic filopodium-spine transition. Hu HT and Hsueh YP, Dev Neurobiol. 2014 Oct;74(10):1011-29. doi: 10.1002/dneu.22181. Epub 2014 Apr 28.
6. Isolation and characterization of mammalian homologues of Caenorhabditis elegans lin-7: localization at cell-cell junctions. Irie M, etal., Oncogene 1999 May 6;18(18):2811-7.
7. Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex. Jo K, etal., J Neurosci. 1999 Jun 1;19(11):4189-99.
8. A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels. Leonoudakis D, etal., J Biol Chem 2004 Apr 30;279(18):19051-63. Epub 2004 Feb 11.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
1 to 12 of 12 rows
PMID:16186258   PMID:17237226  



Lin7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,983,368 - 104,986,795 (-)NCBIGRCr8
mRatBN7.2195,846,888 - 95,849,628 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,846,243 - 95,849,977 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,232,405 - 101,234,980 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,705,082 - 109,707,657 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,995,482 - 102,998,057 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,358,313 - 101,361,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,358,396 - 101,360,971 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,421,965 - 102,425,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,838,781 - 95,841,356 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,916,891 - 95,919,467 (-)NCBI
Celera190,103,272 - 90,105,847 (-)NCBICelera
Cytogenetic Map1q22NCBI
LIN7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,114,370 - 49,118,460 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,114,324 - 49,118,460 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,617,627 - 49,621,717 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,309,430 - 54,313,529 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,309,429 - 54,313,529NCBI
Celera1946,484,840 - 46,488,937 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,993,785 - 45,997,881 (+)NCBIHuRef
CHM1_11949,619,736 - 49,623,829 (+)NCBICHM1_1
T2T-CHM13v2.01952,109,104 - 52,113,194 (+)NCBIT2T-CHM13v2.0
Lin7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,017,315 - 45,019,988 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,017,315 - 45,020,007 (-)EnsemblGRCm39 Ensembl
GRCm38745,367,891 - 45,370,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,367,891 - 45,370,583 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,623,261 - 52,625,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,235,933 - 45,238,606 (-)NCBIMGSCv36mm8
Celera740,823,918 - 40,826,591 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.28NCBI
Lin7b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,611,004 - 1,614,320 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,610,924 - 1,613,736 (-)NCBIChiLan1.0ChiLan1.0
LIN7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,228,966 - 55,233,355 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,148,666 - 57,152,856 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,125,272 - 46,129,450 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,045,557 - 55,055,761 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,047,704 - 55,055,761 (+)Ensemblpanpan1.1panPan2
LIN7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,332,623 - 107,336,099 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,332,623 - 107,336,302 (-)NCBICanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,332,623 - 107,336,302 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01107,857,485 - 107,860,971 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,857,485 - 107,861,164 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,525,392 - 107,528,877 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,171,615 - 107,175,101 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,007,220 - 108,010,706 (-)NCBIUU_Cfam_GSD_1.0
Lin7b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,441,132 - 21,444,484 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,059,359 - 3,062,707 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,059,365 - 3,062,674 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIN7B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,309,535 - 54,313,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,309,552 - 54,313,138 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,015,309 - 50,018,898 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIN7B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,337,437 - 42,341,865 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,337,806 - 42,342,128 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,230,042 - 22,234,175 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lin7b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,965,537 - 4,968,516 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,965,537 - 4,968,574 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Lin7b
1 total Variants

Predicted Target Of
Summary Value
Count of predictions:81
Count of miRNA genes:65
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000028164
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat

1 to 10 of 45 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 49 113 53 52 22 19 22 6 172 91 93 44 56 30



Ensembl Acc Id: ENSRNOT00000028164   ⟹   ENSRNOP00000028164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,846,243 - 95,849,977 (-)Ensembl
Rnor_6.0 Ensembl1101,358,396 - 101,360,971 (-)Ensembl
RefSeq Acc Id: NM_021758   ⟹   NP_068526
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,983,368 - 104,986,078 (-)NCBI
mRatBN7.2195,846,888 - 95,849,598 (-)NCBI
Rnor_6.01101,358,396 - 101,360,971 (-)NCBI
Rnor_5.01102,421,965 - 102,425,037 (-)NCBI
RGSC_v3.4195,838,781 - 95,841,356 (-)RGD
Celera190,103,272 - 90,105,847 (-)RGD
Sequence:
RefSeq Acc Id: XM_063272473   ⟹   XP_063128543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,983,479 - 104,986,795 (-)NCBI
Protein RefSeqs NP_068526 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128543 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC78072 (Get FASTA)   NCBI Sequence Viewer  
  EDM07368 (Get FASTA)   NCBI Sequence Viewer  
  EDM07369 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028164.2
  ENSRNOP00000107896
GenBank Protein Q9Z252 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_068526   ⟸   NM_021758
- UniProtKB: Q9Z252 (UniProtKB/Swiss-Prot),   A6JB15 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028164   ⟸   ENSRNOT00000028164
RefSeq Acc Id: XP_063128543   ⟸   XM_063272473
- Peptide Label: isoform X1
L27   PDZ

Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z252-F1-model_v2 AlphaFold Q9Z252 1-207 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 30 of 30 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-59690 BioCyc
Ensembl Genes ENSRNOG00000020746 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028164.4 UniProtKB/Swiss-Prot
  ENSRNOT00000165243 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot
  L27 domain UniProtKB/Swiss-Prot
InterPro L27_C UniProtKB/Swiss-Prot
  L27_dom UniProtKB/Swiss-Prot
  L27_dom_sf UniProtKB/Swiss-Prot
  LIN7 UniProtKB/Swiss-Prot
  MAM_complex_regulator UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:60377 UniProtKB/Swiss-Prot
NCBI Gene 60377 ENTREZGENE
PANTHER PROTEIN LIN-7 HOMOLOG UniProtKB/Swiss-Prot
Pfam L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
PhenoGen Lin7b PhenoGen
PIRSF Lin-7_homologue UniProtKB/Swiss-Prot
PROSITE L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020746 RatGTEx
SMART L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF101288 UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
UniProt A6JB15 ENTREZGENE, UniProtKB/TrEMBL
  A6JB16_RAT UniProtKB/TrEMBL
  LIN7B_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 30 of 30 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Lin7b  lin-7 homolog B, crumbs cell polarity complex component  Lin7b  lin-7 homolog B (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-19 Lin7b  lin-7 homolog B (C. elegans)  Lin7b  lin-7 homolog b (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Lin7b  lin-7 homolog b (C. elegans)  Veli1a  lin-7-A  Symbol and Name updated 1299863 APPROVED
2002-08-07 Veli1a  lin-7-A      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_homology one of several homologs of C.elegans lin-7 633233