Sf1 (splicing factor 1) - Rat Genome Database

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Gene: Sf1 (splicing factor 1) Rattus norvegicus
Analyze
Symbol: Sf1
Name: splicing factor 1
RGD ID: 620645
Description: Predicted to enable identical protein binding activity and mRNA binding activity. Involved in negative regulation of smooth muscle cell proliferation. Predicted to be located in nuclear body. Predicted to be part of U2AF complex and spliceosomal complex. Predicted to be active in nucleus. Used to study ischemia. Orthologous to human SF1 (splicing factor 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Zfp162; zinc finger protein 162
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,090,256 - 213,112,688 (+)NCBIGRCr8
mRatBN7.21203,670,016 - 203,683,432 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,670,018 - 203,684,330 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,018,848 - 212,032,153 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01219,115,356 - 219,128,639 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,806,411 - 211,819,694 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,735,512 - 221,749,216 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,735,517 - 221,749,086 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,723,282 - 228,737,009 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,146,177 - 209,159,459 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11209,312,189 - 209,313,441 (+)NCBI
Celera1201,203,443 - 201,216,725 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1Ratischemia  IDA 727772 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1RatBardet-Biedl syndrome  ISOSF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Bardet-Biedl syndromeClinVarPMID:12118255 more ...
Sf1Ratglycogen storage disease V  ISOSF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Glycogen storage disease and type VClinVarPMID:12118255 more ...
Sf1Ratintellectual disability  ISOSF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Sf1Ratleukocyte adhesion deficiency 3  ISOSF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Leukocyte adhesion deficiency 3ClinVarPMID:28492532
Sf1Ratmultiple endocrine neoplasia type 1  ISOSF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Multiple endocrine neoplasia and type 1ClinVarPMID:17065424 more ...
Sf1RatNeurodevelopmental Disorders  ISOSF1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1Ratmelanoma  ISOSF1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22535842

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1Rat(+)-catechin decreases expressionISOSF1 (Homo sapiens)6480464Catechin results in decreased expression of SF1 mRNACTDPMID:15465739
Sf1Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SF1 mRNA]CTDPMID:31150632
Sf1Rat(-)-epigallocatechin 3-gallate multiple interactionsISOSF1 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SF1 mRNACTDPMID:22079256
Sf1Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expressionISOSf1 (Mus musculus)6480464o and p'-DDT results in increased expression of SF1 mRNACTDPMID:24096037
Sf1Rat1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expressionEXP 6480464o and p'-DDT results in increased expression of SF1 mRNACTDPMID:24096037
Sf1Rat1,2-dimethylhydrazine affects expressionISOSf1 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of SF1 mRNACTDPMID:22206623
Sf1Rat14-Deoxy-11,12-didehydroandrographolide decreases expressionISOSF1 (Homo sapiens)648046414-deoxy-11 and 12-didehydroandrographolide results in decreased expression of SF1 mRNACTDPMID:22101062
Sf1Rat17alpha-ethynylestradiol increases expressionISOSf1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of SF1 mRNACTDPMID:24096037
Sf1Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of SF1 mRNACTDPMID:24096037
Sf1Rat17beta-estradiol multiple interactionsISOSF1 (Homo sapiens)6480464Estradiol promotes the reaction [SF1 protein binds to ESR1 protein]CTDPMID:27156127
Sf1Rat17beta-estradiol increases expressionISOSF1 (Homo sapiens)6480464Estradiol results in increased expression of SF1 mRNACTDPMID:31614463
Sf1Rat17beta-hydroxy-5alpha-androstan-3-one decreases expressionISOSF1 (Homo sapiens)6480464Dihydrotestosterone results in decreased expression of SF1 mRNACTDPMID:29556062
Sf1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of SF1 mRNACTDPMID:21215274
Sf1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of SF1 mRNACTDPMID:34747641
Sf1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOSf1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of SF1 mRNACTDPMID:21570461
Sf1Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of SF1 mRNACTDPMID:21346803
Sf1Rat2,6-dimethoxyphenol multiple interactionsISOSF1 (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 more ...CTDPMID:38598786
Sf1Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of SF1 mRNACTDPMID:21346803
Sf1Rat2-methylcholine affects expressionISOSF1 (Homo sapiens)6480464beta-methylcholine affects the expression of SF1 mRNACTDPMID:21179406
Sf1Rat3,4-methylenedioxymethamphetamine increases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of SF1 mRNACTDPMID:30071829

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1RatLeydig cell differentiation acts_upstream_of_or_withinISOSf1 (Mus musculus)1624291MGI:94891 PMID:17495005RGDPMID:17495005
Sf1Ratmale sex determination acts_upstream_of_or_withinISOSf1 (Mus musculus)1624291MGI:94891 PMID:17495005RGDPMID:17495005
Sf1RatmRNA processing involved_inIEAUniProtKB-KW:KW-05071600115GO_REF:0000043UniProtGO_REF:0000043
Sf1RatmRNA splicing, via spliceosome involved_inIEAUniRule:UR0014537611600115GO_REF:0000104UniProtGO_REF:0000104
Sf1Ratnegative regulation of smooth muscle cell proliferation  IMP 632653 RGD 
Sf1Ratnuclear body organization acts_upstream_of_or_withinISOSf1 (Mus musculus)1624291 PMID:25145264RGDPMID:25145264
Sf1Ratregulation of mRNA splicing, via spliceosome involved_inIBAFB:FBgn0022984 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Sf1Ratregulation of primary metabolic process involved_inIEAARBA:ARBA000262841600115GO_REF:0000117UniProtGO_REF:0000117
Sf1Ratregulation of steroid biosynthetic process acts_upstream_of_or_withinISOSf1 (Mus musculus)1624291MGI:94891 PMID:17495005RGDPMID:17495005
Sf1RatRNA splicing involved_inIEAUniProtKB-KW:KW-05081600115GO_REF:0000043UniProtGO_REF:0000043
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Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1Ratnuclear body located_inISOSf1 (Mus musculus)1624291 PMID:25145264RGDPMID:25145264
Sf1Ratnucleoplasm located_inISOSF1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Sf1Ratnucleoplasm located_inIEAUniProtKB:Q15637 and ensembl:ENSP000003666071600115GO_REF:0000107EnsemblGO_REF:0000107
Sf1Ratnucleus is_active_inIBAFB:FBgn0022984 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Sf1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Sf1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Sf1Ratspliceosomal complex part_ofISOSF1 (Homo sapiens)1624291 PMID:23273425 and PMID:9731529RGDPMID:23273425 and PMID:9731529
Sf1Ratspliceosomal complex part_ofIEAUniProtKB:Q15637 and ensembl:ENSP000003666071600115GO_REF:0000107EnsemblGO_REF:0000107
Sf1Ratspliceosomal complex part_ofIEAUniProtKB-KW:KW-07471600115GO_REF:0000043UniProtGO_REF:0000043
Sf1RatU2AF complex part_ofISOSF1 (Homo sapiens)1624291 PMID:23273425RGDPMID:23273425
Sf1RatU2AF complex part_ofIEAUniProtKB:Q15637 and ensembl:ENSP000003666071600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1Ratidentical protein binding enablesISOSF1 (Homo sapiens)1624291UniProtKB:Q15637 more ...RGDPMID:22365833 and PMID:26420826
Sf1Ratidentical protein binding enablesIEAUniProtKB:Q15637 and ensembl:ENSP000003666071600115GO_REF:0000107EnsemblGO_REF:0000107
Sf1Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Sf1RatmRNA binding enablesIBAFB:FBgn0264491 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Sf1Ratnucleic acid binding enablesIEAInterPro:IPR001878 and InterPro:IPR0040871600115GO_REF:0000002InterProGO_REF:0000002
Sf1Ratpre-mRNA branch point binding enablesIEAUniRule:UR0014537611600115GO_REF:0000104UniProtGO_REF:0000104
Sf1Ratprotein binding enablesISOSF1 (Homo sapiens)1624291UniProtKB:O14979 more ...RGDPMID:10449420 more ...
Sf1Ratprotein binding enablesISOSF1 (Homo sapiens) and UniProtKB:Q15637-41624291UniProtKB:O14787-2 more ...RGDPMID:32296183 and PMID:32814053
Sf1RatRNA binding enablesIEAUniProtKB-KW:KW-06941600115GO_REF:0000043UniProtGO_REF:0000043
Sf1RatRNA binding enablesIEAUniRule:UR0004154221600115GO_REF:0000104UniProtGO_REF:0000104
Sf1RatRNA binding enablesISOSf1 (Mus musculus)1624291MGI:2444886 PMID:25145264RGDPMID:25145264
Sf1RatRNA binding enablesIEAInterPro:IPR0366121600115GO_REF:0000002InterProGO_REF:0000002
Sf1Ratzinc ion binding enablesIEAUniRule:UR0014537611600115GO_REF:0000104UniProtGO_REF:0000104
Sf1Ratzinc ion binding enablesIEAInterPro:IPR0018781600115GO_REF:0000002InterProGO_REF:0000002
Sf1Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
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RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sf1Ratspliceosome pathway   ISOSF1 (Homo sapiens)9686089 RGD 

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#
Reference Title
Reference Citation
1. Cytokine-induced down-regulation of zfm1/splicing factor-1 promotes smooth muscle cell proliferation. Cattaruzza M, etal., J Biol Chem 2002 Feb 22;277(8):6582-9.
2. ZFM1/SF1 mRNA in rat and gerbil brain after global ischaemia. Covini N, etal., Eur J Neurosci 1999 Mar;11(3):781-7.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
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PMID:8889548   PMID:9731529   PMID:12477932   PMID:14988433   PMID:17495005   PMID:22365833   PMID:22658674   PMID:22681889   PMID:25145264   PMID:26420826   PMID:31505169   PMID:34713933  



Sf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81213,090,256 - 213,112,688 (+)NCBIGRCr8
mRatBN7.21203,670,016 - 203,683,432 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,670,018 - 203,684,330 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1212,018,848 - 212,032,153 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01219,115,356 - 219,128,639 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,806,411 - 211,819,694 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,735,512 - 221,749,216 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,735,517 - 221,749,086 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01228,723,282 - 228,737,009 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,146,177 - 209,159,459 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11209,312,189 - 209,313,441 (+)NCBI
Celera1201,203,443 - 201,216,725 (+)NCBICelera
Cytogenetic Map1q43NCBI
SF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381164,764,606 - 64,778,542 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1164,764,606 - 64,778,786 (-)EnsemblGRCh38hg38GRCh38
GRCh371164,532,078 - 64,546,014 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361164,288,654 - 64,302,817 (-)NCBINCBI36Build 36hg18NCBI36
Build 341164,288,653 - 64,302,817NCBI
Celera1161,858,574 - 61,872,815 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1160,858,921 - 60,873,339 (-)NCBIHuRef
CHM1_11164,415,846 - 64,430,091 (-)NCBICHM1_1
T2T-CHM13v2.01164,757,911 - 64,771,848 (-)NCBIT2T-CHM13v2.0
Sf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,413,952 - 6,428,060 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl196,413,720 - 6,428,060 (+)EnsemblGRCm39 Ensembl
GRCm38196,363,673 - 6,378,038 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,363,690 - 6,378,030 (+)EnsemblGRCm38mm10GRCm38
MGSCv37196,363,690 - 6,378,038 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36196,364,088 - 6,376,425 (+)NCBIMGSCv36mm8
Celera196,236,708 - 6,251,056 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.48NCBI
Sf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542220,391,722 - 20,551,870 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542220,391,340 - 20,406,555 (+)NCBIChiLan1.0ChiLan1.0
SF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2965,990,503 - 66,006,673 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,033,499 - 67,048,030 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,120,126 - 60,134,279 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,461,318 - 63,473,350 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,461,318 - 63,473,355 (-)Ensemblpanpan1.1panPan2
SF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11852,380,058 - 52,393,833 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1852,380,211 - 52,393,048 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,987,426 - 51,001,160 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01853,421,292 - 53,435,068 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1853,421,043 - 53,435,063 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11852,516,258 - 52,529,989 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01852,102,165 - 52,115,924 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,886,303 - 52,900,036 (+)NCBIUU_Cfam_GSD_1.0
Sf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049478,091,417 - 8,104,506 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365994,533,795 - 4,546,853 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365994,533,664 - 4,546,857 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,391,383 - 7,404,948 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,391,295 - 7,404,693 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,522,689 - 6,537,534 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,456,524 - 9,470,920 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl19,456,971 - 9,472,396 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038106,845,714 - 106,860,060 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476721,606,065 - 21,621,830 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476721,606,059 - 21,621,831 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Sf1
31 total Variants

Predicted Target Of
Summary Value
Count of predictions:287
Count of miRNA genes:180
Interacting mature miRNAs:207
Transcripts:ENSRNOT00000028628, ENSRNOT00000044866
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat

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RH142165  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,682,949 - 203,683,163 (+)MAPPERmRatBN7.2
Rnor_6.01221,748,734 - 221,748,947NCBIRnor6.0
Rnor_5.01228,736,523 - 228,736,736UniSTSRnor5.0
RGSC_v3.41209,159,105 - 209,159,318UniSTSRGSC3.4
Celera1201,216,371 - 201,216,584UniSTS
RH 3.4 Map11537.4UniSTS
Cytogenetic Map1q43UniSTS
RH141827  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,668,377 - 203,668,569 (+)MAPPERmRatBN7.2
Rnor_6.01221,733,874 - 221,734,065NCBIRnor6.0
Rnor_5.01228,721,663 - 228,721,854UniSTSRnor5.0
RGSC_v3.41209,144,534 - 209,144,725UniSTSRGSC3.4
Celera1201,201,800 - 201,201,991UniSTS
RH 3.4 Map11523.4UniSTS
Cytogenetic Map1q43UniSTS
stSG635675  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,674,648 - 203,675,797 (+)MAPPERmRatBN7.2
Rnor_6.01221,740,144 - 221,741,292NCBIRnor6.0
Rnor_5.01228,727,933 - 228,729,081UniSTSRnor5.0
RGSC_v3.41209,150,804 - 209,151,952UniSTSRGSC3.4
Celera1201,208,070 - 201,209,218UniSTS
Cytogenetic Map1q43UniSTS
ECD02238  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,681,321 - 203,682,166 (+)MAPPERmRatBN7.2
Rnor_6.01221,747,106 - 221,747,950NCBIRnor6.0
Rnor_5.01228,734,895 - 228,735,739UniSTSRnor5.0
RGSC_v3.41209,157,477 - 209,158,321UniSTSRGSC3.4
Celera1201,214,743 - 201,215,587UniSTS
Cytogenetic Map1q43UniSTS
REN56369  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,681,660 - 203,681,904 (+)MAPPERmRatBN7.2
Rnor_6.01221,747,445 - 221,747,688NCBIRnor6.0
Rnor_5.01228,735,234 - 228,735,477UniSTSRnor5.0
RGSC_v3.41209,157,816 - 209,158,059UniSTSRGSC3.4
Celera1201,215,082 - 201,215,325UniSTS
Cytogenetic Map1q43UniSTS
REN56368  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,681,895 - 203,682,157 (+)MAPPERmRatBN7.2
Rnor_6.01221,747,680 - 221,747,941NCBIRnor6.0
Rnor_5.01228,735,469 - 228,735,730UniSTSRnor5.0
RGSC_v3.41209,158,051 - 209,158,312UniSTSRGSC3.4
Celera1201,215,317 - 201,215,578UniSTS
Cytogenetic Map1q43UniSTS
REN56367  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,682,128 - 203,682,362 (+)MAPPERmRatBN7.2
Rnor_6.01221,747,913 - 221,748,146NCBIRnor6.0
Rnor_5.01228,735,702 - 228,735,935UniSTSRnor5.0
RGSC_v3.41209,158,284 - 209,158,517UniSTSRGSC3.4
Celera1201,215,550 - 201,215,783UniSTS
Cytogenetic Map1q43UniSTS
REN56392  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21203,676,337 - 203,676,588 (+)MAPPERmRatBN7.2
Rnor_6.01221,741,833 - 221,742,083NCBIRnor6.0
Rnor_5.01228,729,622 - 228,729,872UniSTSRnor5.0
RGSC_v3.41209,152,493 - 209,152,743UniSTSRGSC3.4
Celera1201,209,759 - 201,210,009UniSTS
Cytogenetic Map1q43UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 30 of 38 rows
RefSeq Transcripts NM_001110793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_058210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039080641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF079873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 38 rows

Ensembl Acc Id: ENSRNOT00000028628   ⟹   ENSRNOP00000028628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1203,671,415 - 203,683,424 (+)Ensembl
Rnor_6.0 Ensembl1221,735,517 - 221,749,086 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000044866   ⟹   ENSRNOP00000041676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1203,670,032 - 203,683,300 (+)Ensembl
Rnor_6.0 Ensembl1221,735,528 - 221,749,086 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100785   ⟹   ENSRNOP00000079109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1203,670,272 - 203,684,330 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110004   ⟹   ENSRNOP00000082510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1203,670,018 - 203,682,665 (+)Ensembl
RefSeq Acc Id: NM_001110793   ⟹   NP_001104263
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,099,281 - 213,112,563 (+)NCBI
mRatBN7.21203,670,021 - 203,683,304 (+)NCBI
Rnor_6.01221,735,517 - 221,749,088 (+)NCBI
Rnor_5.01228,723,282 - 228,737,009 (+)NCBI
RGSC_v3.41209,146,177 - 209,159,459 (+)RGD
Celera1201,203,443 - 201,216,725 (+)RGD
Sequence:
RefSeq Acc Id: NM_058210   ⟹   NP_478117
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,099,281 - 213,112,563 (+)NCBI
mRatBN7.21203,670,021 - 203,683,304 (+)NCBI
Rnor_6.01221,735,517 - 221,749,088 (+)NCBI
Rnor_5.01228,723,282 - 228,737,009 (+)NCBI
RGSC_v3.41209,146,177 - 209,159,459 (+)RGD
Celera1201,203,443 - 201,216,725 (+)RGD
Sequence:
RefSeq Acc Id: XM_039080398   ⟹   XP_038936326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
mRatBN7.21203,670,250 - 203,682,270 (+)NCBI
RefSeq Acc Id: XM_039080509   ⟹   XP_038936437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
mRatBN7.21203,670,016 - 203,683,432 (+)NCBI
RefSeq Acc Id: XM_039080582   ⟹   XP_038936510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
mRatBN7.21203,670,016 - 203,683,432 (+)NCBI
RefSeq Acc Id: XM_039080601   ⟹   XP_038936529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
mRatBN7.21203,670,016 - 203,683,426 (+)NCBI
RefSeq Acc Id: XM_039080641   ⟹   XP_038936569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,101,276 - 213,112,688 (+)NCBI
mRatBN7.21203,672,047 - 203,683,257 (+)NCBI
RefSeq Acc Id: XM_063268843   ⟹   XP_063124913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063268911   ⟹   XP_063124981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063268935   ⟹   XP_063125005
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063268967   ⟹   XP_063125037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,101,270 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063268985   ⟹   XP_063125055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,101,276 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269068   ⟹   XP_063125138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,101,276 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269089   ⟹   XP_063125159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269115   ⟹   XP_063125185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,101,276 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269141   ⟹   XP_063125211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269180   ⟹   XP_063125250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269208   ⟹   XP_063125278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,103,847 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269232   ⟹   XP_063125302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,101,276 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269279   ⟹   XP_063125349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,103,932 - 213,112,688 (+)NCBI
RefSeq Acc Id: XM_063269311   ⟹   XP_063125381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81213,090,256 - 213,112,688 (+)NCBI
1 to 30 of 32 rows
Protein RefSeqs NP_001104263 (Get FASTA)   NCBI Sequence Viewer  
  NP_478117 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936326 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936437 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936510 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936529 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936569 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124913 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124981 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125005 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125037 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125055 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125138 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125159 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125185 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125211 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125250 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125278 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125302 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125349 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125381 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC29484 (Get FASTA)   NCBI Sequence Viewer  
  AAH81859 (Get FASTA)   NCBI Sequence Viewer  
  EDM12600 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000028628
  ENSRNOP00000028628.7
  ENSRNOP00000041676
  ENSRNOP00000041676.4
  ENSRNOP00000079109
  ENSRNOP00000079109.1
1 to 30 of 32 rows
1 to 5 of 25 rows
1 to 5 of 25 rows
RefSeq Acc Id: NP_478117   ⟸   NM_058210
- Peptide Label: isoform 2
- UniProtKB: F1LM37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104263   ⟸   NM_001110793
- Peptide Label: isoform 1
- UniProtKB: F1LSC3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000028628   ⟸   ENSRNOT00000028628
Ensembl Acc Id: ENSRNOP00000041676   ⟸   ENSRNOT00000044866
RefSeq Acc Id: XP_038936510   ⟸   XM_039080582
- Peptide Label: isoform X8
CCHC-type

Name Modeler Protein Id AA Range Protein Structure
AF-F1LSC3-F1-model_v2 AlphaFold F1LSC3 1-639 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690699
Promoter ID:EPDNEW_R1222
Type:multiple initiation site
Name:Sf1_1
Description:splicing factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1223  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01221,735,514 - 221,735,574EPDNEW
RGD ID:13690700
Promoter ID:EPDNEW_R1223
Type:initiation region
Name:Sf1_2
Description:splicing factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1222  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01221,735,746 - 221,735,806EPDNEW


1 to 40 of 42 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-56596 BioCyc
Ensembl Genes ENSRNOG00000021085 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028628 ENTREZGENE
  ENSRNOT00000028628.8 UniProtKB/TrEMBL
  ENSRNOT00000044866 ENTREZGENE
  ENSRNOT00000044866.6 UniProtKB/TrEMBL
  ENSRNOT00000100785 ENTREZGENE
  ENSRNOT00000100785.1 UniProtKB/TrEMBL
  ENSRNOT00000110004 ENTREZGENE
  ENSRNOT00000110004.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
  6.10.140.1790 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132476 IMAGE-MGC_LOAD
InterPro BBP-like UniProtKB/TrEMBL
  IPR004087 UniProtKB/TrEMBL
  KH_1_KHDC4/BBP-like UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  SF1-HH UniProtKB/TrEMBL
  SF1-HH_sf UniProtKB/TrEMBL
  Znf_CCHC UniProtKB/TrEMBL
KEGG Report rno:117855 UniProtKB/TrEMBL
MGC_CLONE MGC:93670 IMAGE-MGC_LOAD
NCBI Gene 117855 ENTREZGENE
PANTHER PTHR11208 UniProtKB/TrEMBL
  PTHR11208:SF45 UniProtKB/TrEMBL
Pfam KH_1_3 UniProtKB/TrEMBL
  SF1-HH UniProtKB/TrEMBL
  zf-CCHC UniProtKB/TrEMBL
PhenoGen Sf1 PhenoGen
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
  ZF_CCHC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021085 RatGTEx
SMART SM00322 UniProtKB/TrEMBL
  ZnF_C2HC UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
UniProt A0A8I5ZQ56 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G7I2 ENTREZGENE, UniProtKB/TrEMBL
  A6HZG9 ENTREZGENE, UniProtKB/TrEMBL
  F1LM37 ENTREZGENE, UniProtKB/TrEMBL
  F1LSC3 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 42 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-07-26 Sf1  splicing factor 1  Zfp162  zinc finger protein 162  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-07-08 Zfp162  zinc finger protein 162      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Zfp162  zinc finger protein 162      Symbol and Name status set to provisional 70820 PROVISIONAL