Manea (mannosidase, endo-alpha) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Manea (mannosidase, endo-alpha) Rattus norvegicus
Analyze
Symbol: Manea
Name: mannosidase, endo-alpha
RGD ID: 620327
Description: Enables alpha-mannosidase activity. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. Human ortholog(s) of this gene implicated in anxiety disorder; cocaine dependence; and panic disorder. Orthologous to human MANEA (mannosidase endo-alpha); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: endo-alpha mannosidase; endo-alpha-D-mannosidase; endo-alpha-mannosidase; endomannosidase; Enman; glycoprotein endo-alpha-1,2-mannosidase; rEndo
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8544,992,937 - 45,015,084 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl544,992,937 - 45,015,084 (-)EnsemblGRCr8
mRatBN7.2540,196,373 - 40,218,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl540,196,396 - 40,218,459 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx542,298,331 - 42,311,130 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0543,897,348 - 43,910,147 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0543,826,581 - 43,839,380 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0540,845,103 - 40,867,025 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl540,844,998 - 40,867,023 (-)Ensemblrn6Rnor6.0
Rnor_5.0545,469,290 - 45,491,210 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4541,577,651 - 41,590,456 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera539,058,787 - 39,071,389 (-)NCBICelera
RGSC_v3.1541,576,728 - 41,590,474 (-)NCBI
Cytogenetic Map5q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
Golgi apparatus  (IEA,ISO)
Golgi membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Association of variants in MANEA with cocaine-related behaviors. Farrer LA, etal., Arch Gen Psychiatry. 2009 Mar;66(3):267-74. doi: 10.1001/archgenpsychiatry.2008.538.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder. Jensen KP, etal., Transl Psychiatry. 2014 Jan 28;4(1):e353. doi: 10.1038/tp.2013.122.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Molecular cloning and expression of rat liver endo-alpha-mannosidase, an N-linked oligosaccharide processing enzyme. Spiro MJ, etal., J Biol Chem 1997 Nov 14;272(46):29356-63.
8. Substance dependence low-density whole genome association study in two distinct American populations. Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.
Additional References at PubMed
PMID:12477932   PMID:15677381   PMID:16871372   PMID:18425413  


Genomics

Comparative Map Data
Manea
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8544,992,937 - 45,015,084 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl544,992,937 - 45,015,084 (-)EnsemblGRCr8
mRatBN7.2540,196,373 - 40,218,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl540,196,396 - 40,218,459 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx542,298,331 - 42,311,130 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0543,897,348 - 43,910,147 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0543,826,581 - 43,839,380 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0540,845,103 - 40,867,025 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl540,844,998 - 40,867,023 (-)Ensemblrn6Rnor6.0
Rnor_5.0545,469,290 - 45,491,210 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4541,577,651 - 41,590,456 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera539,058,787 - 39,071,389 (-)NCBICelera
RGSC_v3.1541,576,728 - 41,590,474 (-)NCBI
Cytogenetic Map5q21NCBI
MANEA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38695,577,535 - 95,609,452 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl695,577,485 - 95,609,484 (+)Ensemblhg38GRCh38
GRCh37696,025,411 - 96,057,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36696,132,134 - 96,164,047 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34696,132,133 - 96,164,047NCBI
Celera696,666,751 - 96,698,498 (+)NCBICelera
Cytogenetic Map6q16.1NCBI
HuRef693,458,650 - 93,490,603 (+)NCBIHuRef
CHM1_1696,287,324 - 96,319,327 (+)NCBICHM1_1
T2T-CHM13v2.0696,748,485 - 96,780,392 (+)NCBIT2T-CHM13v2.0
Manea
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39426,324,506 - 26,346,913 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl426,324,506 - 26,346,891 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38426,324,506 - 26,346,918 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl426,324,506 - 26,346,891 (-)Ensemblmm10GRCm38
MGSCv37426,251,653 - 26,273,799 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36426,415,136 - 26,437,282 (-)NCBIMGSCv36mm8
Celera426,032,320 - 26,054,498 (-)NCBICelera
Cytogenetic Map4A3NCBI
cM Map410.92NCBI
Manea
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541121,735,550 - 21,761,750 (+)Ensembl
ChiLan1.0NW_00495541121,729,085 - 21,763,684 (+)NCBIChiLan1.0ChiLan1.0
MANEA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25115,627,414 - 115,666,203 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16113,512,496 - 113,544,251 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0693,428,813 - 93,460,576 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1697,316,022 - 97,347,768 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl697,316,022 - 97,347,768 (+)EnsemblpanPan2panpan1.1
MANEA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11254,156,398 - 54,229,183 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1254,170,184 - 54,225,013 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1253,963,772 - 54,036,664 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01254,972,172 - 55,045,434 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1254,982,280 - 55,042,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11254,294,305 - 54,367,550 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01254,169,174 - 54,241,745 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01254,371,139 - 54,444,695 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Manea
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494688,721,181 - 88,752,631 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366991,975,362 - 2,006,932 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366991,975,391 - 2,006,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MANEA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl162,887,881 - 62,945,583 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1162,887,689 - 62,945,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2171,027,088 - 71,084,858 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MANEA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11320,496,677 - 20,529,201 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1320,496,686 - 20,530,819 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040196,752,522 - 196,783,748 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Manea
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248109,961,154 - 9,998,835 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Manea
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11116,435,819 - 116,457,905 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Manea
119 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:644
Count of miRNA genes:286
Interacting mature miRNAs:368
Transcripts:ENSRNOT00000011576
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)53113042148841739Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
RH135326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2540,197,099 - 40,197,304 (+)MAPPERmRatBN7.2
Rnor_6.0540,845,590 - 40,845,794NCBIRnor6.0
Rnor_5.0545,469,777 - 45,469,981UniSTSRnor5.0
RGSC_v3.4541,575,412 - 41,575,616UniSTSRGSC3.4
Celera539,056,548 - 39,056,752UniSTS
RH 3.4 Map5216.9UniSTS
Cytogenetic Map5q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 165 91 90 59 92 59 6 355 191 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000011576   ⟹   ENSRNOP00000011576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl544,992,937 - 45,015,084 (-)Ensembl
mRatBN7.2 Ensembl540,196,396 - 40,218,459 (-)Ensembl
Rnor_6.0 Ensembl540,844,998 - 40,867,023 (-)Ensembl
RefSeq Acc Id: NM_080785   ⟹   NP_542963
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8544,992,937 - 45,015,084 (-)NCBI
mRatBN7.2540,196,393 - 40,218,540 (-)NCBI
Rnor_6.0540,847,829 - 40,860,634 (-)NCBI
Rnor_5.0545,469,290 - 45,491,210 (-)NCBI
RGSC_v3.4541,577,651 - 41,590,456 (-)RGD
Celera539,058,787 - 39,071,389 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237961   ⟹   XP_006238023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8544,992,937 - 45,015,075 (-)NCBI
mRatBN7.2540,196,373 - 40,218,251 (-)NCBI
Rnor_6.0540,845,103 - 40,866,751 (-)NCBI
Rnor_5.0545,469,290 - 45,491,210 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_542963 (Get FASTA)   NCBI Sequence Viewer  
  XP_006238023 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAT44962 (Get FASTA)   NCBI Sequence Viewer  
  EDL98547 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011576
  ENSRNOP00000011576.4
GenBank Protein Q5GF25 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_542963   ⟸   NM_080785
- UniProtKB: O35390 (UniProtKB/Swiss-Prot),   Q5GF25 (UniProtKB/Swiss-Prot),   A6IIH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238023   ⟸   XM_006237961
- Peptide Label: isoform X1
- UniProtKB: O35390 (UniProtKB/Swiss-Prot),   Q5GF25 (UniProtKB/Swiss-Prot),   A6IIH7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011576   ⟸   ENSRNOT00000011576

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5GF25-F1-model_v2 AlphaFold Q5GF25 1-462 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693607
Promoter ID:EPDNEW_R4132
Type:initiation region
Name:Manea_1
Description:mannosidase, endo-alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0540,866,965 - 40,867,025EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620327 AgrOrtholog
BioCyc Gene G2FUF-41773 BioCyc
BioCyc Pathway PWY-7919 [protein N-glycosylation processing phase (plants and animals)] BioCyc
BioCyc Pathway Image PWY-7919 BioCyc
Ensembl Genes ENSRNOG00000008626 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011576 ENTREZGENE
  ENSRNOT00000011576.7 UniProtKB/Swiss-Prot
Gene3D-CATH Glycosidases UniProtKB/Swiss-Prot
InterPro Glyco_Hydrolase_99 UniProtKB/Swiss-Prot
KEGG Report rno:140808 UniProtKB/Swiss-Prot
NCBI Gene 140808 ENTREZGENE
PANTHER GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE UniProtKB/Swiss-Prot
  PTHR13572 UniProtKB/Swiss-Prot
Pfam Glyco_hydro_99 UniProtKB/Swiss-Prot
PhenoGen Manea PhenoGen
RatGTEx ENSRNOG00000008626 RatGTEx
UniProt A6IIH7 ENTREZGENE, UniProtKB/TrEMBL
  MANEA_RAT UniProtKB/Swiss-Prot
  O35390 ENTREZGENE
  Q5GF25 ENTREZGENE
UniProt Secondary O35390 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Manea  mannosidase, endo-alpha  Enman  endo-alpha-mannosidase  Symbol and Name updated 1299863 APPROVED
2002-08-07 Enman  endo-alpha-mannosidase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in all tissues 632807
gene_protein 451 amino acids; 52 kDa 632807