MANEA (mannosidase endo-alpha) - Rat Genome Database

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Gene: MANEA (mannosidase endo-alpha) Pan paniscus
Analyze
Symbol: MANEA
Name: mannosidase endo-alpha
RGD ID: 11909900
Description: ENCODES a protein that exhibits alpha-mannosidase activity (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); cocaine dependence (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN Golgi membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glycoprotein endo-alpha-1,2-mannosidase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25115,627,414 - 115,666,203 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16113,512,496 - 113,544,251 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0693,428,813 - 93,460,576 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1697,316,022 - 97,347,768 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl697,316,022 - 97,347,768 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
Golgi apparatus  (IEA)
Golgi membrane  (IEA,ISO)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MANEA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25115,627,414 - 115,666,203 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16113,512,496 - 113,544,251 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0693,428,813 - 93,460,576 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1697,316,022 - 97,347,768 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl697,316,022 - 97,347,768 (+)Ensemblpanpan1.1panPan2
MANEA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38695,577,535 - 95,609,452 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl695,577,485 - 95,609,470 (+)EnsemblGRCh38hg38GRCh38
GRCh37696,025,411 - 96,057,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36696,132,134 - 96,164,047 (+)NCBINCBI36Build 36hg18NCBI36
Build 34696,132,133 - 96,164,047NCBI
Celera696,666,751 - 96,698,498 (+)NCBICelera
Cytogenetic Map6q16.1NCBI
HuRef693,458,650 - 93,490,603 (+)NCBIHuRef
CHM1_1696,287,324 - 96,319,327 (+)NCBICHM1_1
T2T-CHM13v2.0696,748,485 - 96,780,392 (+)NCBIT2T-CHM13v2.0
Manea
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39426,324,506 - 26,346,913 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl426,324,506 - 26,346,891 (-)EnsemblGRCm39 Ensembl
GRCm38426,324,506 - 26,346,918 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl426,324,506 - 26,346,891 (-)EnsemblGRCm38mm10GRCm38
MGSCv37426,251,653 - 26,273,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36426,415,136 - 26,437,282 (-)NCBIMGSCv36mm8
Celera426,032,320 - 26,054,498 (-)NCBICelera
Cytogenetic Map4A3NCBI
cM Map410.92NCBI
Manea
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8544,992,937 - 45,015,084 (-)NCBIGRCr8
mRatBN7.2540,196,373 - 40,218,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl540,196,396 - 40,218,459 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx542,298,331 - 42,311,130 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0543,897,348 - 43,910,147 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0543,826,581 - 43,839,380 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0540,845,103 - 40,867,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl540,844,998 - 40,867,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0545,469,290 - 45,491,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4541,577,651 - 41,590,456 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1541,576,728 - 41,590,474 (-)NCBI
Celera539,058,787 - 39,071,389 (-)NCBICelera
Cytogenetic Map5q21NCBI
Manea
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541121,735,550 - 21,761,750 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541121,729,085 - 21,763,684 (+)NCBIChiLan1.0ChiLan1.0
MANEA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11254,156,398 - 54,229,183 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1254,170,184 - 54,225,013 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1253,963,772 - 54,036,664 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01254,972,172 - 55,045,434 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1254,982,280 - 55,042,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11254,294,305 - 54,367,550 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01254,169,174 - 54,241,745 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01254,371,139 - 54,444,695 (+)NCBIUU_Cfam_GSD_1.0
Manea
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494688,721,181 - 88,752,631 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366991,975,362 - 2,006,932 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366991,975,391 - 2,006,816 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MANEA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl162,887,881 - 62,945,583 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1162,887,689 - 62,945,586 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2171,027,088 - 71,084,858 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MANEA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11320,496,677 - 20,529,201 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1320,496,686 - 20,530,819 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040196,752,522 - 196,783,748 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Manea
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248109,961,154 - 9,998,835 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003824376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000064636   ⟹   ENSPPAP00000041710
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl697,316,022 - 97,347,768 (+)Ensembl
RefSeq Acc Id: XM_003824376   ⟹   XP_003824424
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25115,627,414 - 115,666,203 (+)NCBI
NHGRI_mPanPan16113,512,496 - 113,544,251 (+)NCBI
Mhudiblu_PPA_v0693,428,813 - 93,460,576 (+)NCBI
PanPan1.1697,316,022 - 97,347,768 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003824424 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000041710.1
Reference Protein Sequences
RefSeq Acc Id: XP_003824424   ⟸   XM_003824376
- Sequence:
RefSeq Acc Id: ENSPPAP00000041710   ⟸   ENSPPAT00000064636


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043462 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064636.1 UniProtKB/TrEMBL
Gene3D-CATH Glycosidases UniProtKB/TrEMBL
InterPro Glyco_Hydrolase_99 UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
KEGG Report pps:100996027 UniProtKB/TrEMBL
NCBI Gene MANEA ENTREZGENE
PANTHER GLYCOPROTEIN ENDO-ALPHA-1,2-MANNOSIDASE UniProtKB/TrEMBL
  PTHR13572 UniProtKB/TrEMBL
Pfam Glyco_hydro_99 UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/TrEMBL
UniProt A0A2R9CIF7_PANPA UniProtKB/TrEMBL