Hip1 (huntingtin interacting protein 1) - Rat Genome Database

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Gene: Hip1 (huntingtin interacting protein 1) Rattus norvegicus
Analyze
Symbol: Hip1
Name: huntingtin interacting protein 1
RGD ID: 620305
Description: Enables clathrin binding activity. Involved in clathrin coat assembly. Located in clathrin-coated vesicle. Is active in glutamatergic synapse; postsynaptic membrane; and presynapse. Orthologous to human HIP1 (huntingtin interacting protein 1); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: huntingtin-interacting protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Hypk-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,769,868 - 26,904,367 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,769,961 - 26,904,296 (+)EnsemblGRCr8
mRatBN7.21221,133,364 - 21,267,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,133,406 - 21,267,725 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1222,275,219 - 22,409,598 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,887,561 - 23,021,930 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,954,027 - 22,088,410 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,180,795 - 24,315,373 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,180,937 - 24,315,373 (+)Ensemblrn6Rnor6.0
Rnor_5.01226,178,145 - 26,312,676 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41222,287,861 - 22,422,163 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,895,802 - 23,030,274 (+)NCBICelera
RGSC_v3.11222,396,520 - 22,408,493 (+)NCBI
Cytogenetic Map12q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
clotrimazole  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
decabromodiphenyl ether  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glycine betaine  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
kojic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
nitrofen  (EXP)
p-toluidine  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
phosgene  (ISO)
pinostrobin  (ISO)
potassium chromate  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tamoxifen  (ISO)
testosterone  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain. Legendre-Guillemin V, etal., J Biol Chem 2002 May 31;277(22):19897-904.
4. Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins. Mishra SK, etal., J Biol Chem 2001 Dec 7;276(49):46230-6. Epub 2001 Sep 27.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Partially overlapping distribution of epsin1 and HIP1 at the synapse: analysis by immunoelectron microscopy. Yao PJ, etal., J Comp Neurol. 2006 Jan 10;494(2):368-79.
Additional References at PubMed
PMID:11007801   PMID:11517213   PMID:11532990   PMID:11604514   PMID:11788820   PMID:12477932   PMID:14732715   PMID:15533940   PMID:15906374   PMID:18790740   PMID:20074057   PMID:22871113  
PMID:38726004  


Genomics

Comparative Map Data
Hip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,769,868 - 26,904,367 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,769,961 - 26,904,296 (+)EnsemblGRCr8
mRatBN7.21221,133,364 - 21,267,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,133,406 - 21,267,725 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1222,275,219 - 22,409,598 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,887,561 - 23,021,930 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,954,027 - 22,088,410 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,180,795 - 24,315,373 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,180,937 - 24,315,373 (+)Ensemblrn6Rnor6.0
Rnor_5.01226,178,145 - 26,312,676 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41222,287,861 - 22,422,163 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,895,802 - 23,030,274 (+)NCBICelera
RGSC_v3.11222,396,520 - 22,408,493 (+)NCBI
Cytogenetic Map12q12NCBI
HIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38775,533,298 - 75,738,941 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl775,533,298 - 75,738,986 (-)Ensemblhg38GRCh38
GRCh37775,162,619 - 75,368,259 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,001,345 - 75,206,215 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34774,808,059 - 75,012,930NCBI
Celera770,031,212 - 70,236,048 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef770,248,359 - 70,453,525 (-)NCBIHuRef
CHM1_1775,092,714 - 75,298,283 (-)NCBICHM1_1
T2T-CHM13v2.0776,820,630 - 77,026,024 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2774,495,683 - 74,701,354 (-)NCBI
Hip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,435,350 - 135,574,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,435,385 - 135,573,974 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385135,406,496 - 135,545,323 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,406,531 - 135,545,120 (-)Ensemblmm10GRCm38
MGSCv375135,882,388 - 136,020,992 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365135,692,653 - 135,829,742 (-)NCBIMGSCv36mm8
Celera5132,418,220 - 132,556,655 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.18NCBI
Hip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,392,921 - 14,529,213 (-)Ensembl
ChiLan1.0NW_00495545614,389,282 - 14,529,317 (-)NCBIChiLan1.0ChiLan1.0
HIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2694,215,412 - 94,420,460 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17142,480,052 - 142,685,098 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0768,281,899 - 68,464,233 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1782,187,193 - 82,193,058 (-)NCBIPanPan1.1PanPan1.1panPan2
HIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,957,760 - 7,115,676 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,961,053 - 7,115,618 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha68,654,406 - 8,812,467 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.066,778,147 - 6,936,340 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl66,778,151 - 6,936,438 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.166,747,968 - 6,905,918 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.066,711,133 - 6,869,280 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,874,374 - 7,032,555 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,467,552 - 131,540,287 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365432,522,154 - 2,565,376 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365432,496,301 - 2,569,019 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,416,475 - 10,578,366 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1310,416,418 - 10,578,374 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,176,878 - 10,282,562 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,805,985 - 10,007,931 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl289,807,672 - 9,914,047 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660706,432,081 - 6,658,245 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474014,464,372 - 14,607,130 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474014,460,742 - 14,607,203 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hip1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11618,476,398 - 18,606,670 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hip1
1404 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:560
Count of miRNA genes:269
Interacting mature miRNAs:361
Transcripts:ENSRNOT00000030497
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
11530002Bss119Bone structure and strength QTL 11916.394e-17lumbar vertebra area (VT:0010570)lumbar vertebra area (CMO:0001688)122651003826983303Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat

Markers in Region
D12Rat33  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81226,782,759 - 26,782,998 (+)Marker Load Pipeline
mRatBN7.21221,146,177 - 21,146,418 (+)MAPPERmRatBN7.2
Rnor_6.01224,193,707 - 24,193,945NCBIRnor6.0
Rnor_5.01226,191,010 - 26,191,248UniSTSRnor5.0
RGSC_v3.41222,300,630 - 22,300,868UniSTSRGSC3.4
RGSC_v3.41222,300,576 - 22,300,992RGDRGSC3.4
Celera1222,908,570 - 22,908,808UniSTS
RGSC_v3.11222,287,675 - 22,287,913RGD
RH 3.4 Map12336.2RGD
RH 3.4 Map12336.2UniSTS
RH 2.0 Map12225.2RGD
SHRSP x BN Map1223.8199RGD
FHH x ACI Map1210.1799RGD
Cytogenetic Map12q12UniSTS
BE116737  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,145,698 - 21,145,874 (+)MAPPERmRatBN7.2
Rnor_6.01224,193,228 - 24,193,403NCBIRnor6.0
Rnor_5.01226,190,531 - 26,190,706UniSTSRnor5.0
RGSC_v3.41222,300,151 - 22,300,326UniSTSRGSC3.4
Celera1222,908,091 - 22,908,266UniSTS
RH 3.4 Map12337.9UniSTS
Cytogenetic Map12q12UniSTS
RH128125  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,267,317 - 21,267,526 (+)MAPPERmRatBN7.2
Rnor_6.01224,314,966 - 24,315,174NCBIRnor6.0
Rnor_5.01226,312,269 - 26,312,477UniSTSRnor5.0
RGSC_v3.41222,421,756 - 22,421,964UniSTSRGSC3.4
Celera1223,029,867 - 23,030,075UniSTS
RH 3.4 Map12338.1UniSTS
Cytogenetic Map12q12UniSTS
RH128368  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,185,779 - 21,185,995 (+)MAPPERmRatBN7.2
Rnor_6.01224,233,606 - 24,233,821NCBIRnor6.0
Rnor_5.01226,230,909 - 26,231,124UniSTSRnor5.0
RGSC_v3.41222,340,224 - 22,340,439UniSTSRGSC3.4
Celera1222,948,620 - 22,948,835UniSTS
RH 3.4 Map12339.4UniSTS
Cytogenetic Map12q12UniSTS
RH133161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,264,284 - 21,264,492 (+)MAPPERmRatBN7.2
Rnor_6.01224,311,933 - 24,312,140NCBIRnor6.0
Rnor_5.01226,309,236 - 26,309,443UniSTSRnor5.0
RGSC_v3.41222,418,723 - 22,418,930UniSTSRGSC3.4
Celera1223,026,834 - 23,027,041UniSTS
RH 3.4 Map12338.5UniSTS
Cytogenetic Map12q12UniSTS
AA964673  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,265,289 - 21,265,406 (+)MAPPERmRatBN7.2
Rnor_6.01224,312,938 - 24,313,054NCBIRnor6.0
Rnor_5.01226,310,241 - 26,310,357UniSTSRnor5.0
RGSC_v3.41222,419,728 - 22,419,844UniSTSRGSC3.4
Celera1223,027,839 - 23,027,955UniSTS
RH 3.4 Map12338.5UniSTS
Cytogenetic Map12q12UniSTS
AU047037  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21870,634,718 - 70,634,762 (-)MAPPERmRatBN7.2
mRatBN7.21221,166,067 - 21,166,275 (+)MAPPERmRatBN7.2
mRatBN7.2195,470,595 - 95,470,642 (+)MAPPERmRatBN7.2
mRatBN7.298,240,881 - 8,240,924 (-)MAPPERmRatBN7.2
mRatBN7.2717,956,378 - 17,956,423 (-)MAPPERmRatBN7.2
mRatBN7.21071,494,412 - 71,494,456 (-)MAPPERmRatBN7.2
mRatBN7.21710,516,594 - 10,516,637 (-)MAPPERmRatBN7.2
mRatBN7.28107,082,514 - 107,082,558 (+)MAPPERmRatBN7.2
mRatBN7.21945,524,578 - 45,524,621 (-)MAPPERmRatBN7.2
mRatBN7.24168,388,066 - 168,388,109 (-)MAPPERmRatBN7.2
Rnor_6.01224,213,901 - 24,214,110NCBIRnor6.0
Rnor_5.01226,211,204 - 26,211,413UniSTSRnor5.0
RGSC_v3.41222,320,518 - 22,320,727UniSTSRGSC3.4
Celera1222,928,914 - 22,929,123UniSTS
Cytogenetic Map12q12UniSTS
RH135309  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,170,851 - 21,171,053 (+)MAPPERmRatBN7.2
Rnor_6.01224,218,687 - 24,218,888NCBIRnor6.0
Rnor_5.01226,215,990 - 26,216,191UniSTSRnor5.0
RGSC_v3.41222,325,304 - 22,325,505UniSTSRGSC3.4
Celera1222,933,700 - 22,933,901UniSTS
RH 3.4 Map12337.6UniSTS
Cytogenetic Map12q12UniSTS
AU048794  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,160,147 - 21,160,379 (+)MAPPERmRatBN7.2
mRatBN7.2870,861,070 - 70,862,047 (+)MAPPERmRatBN7.2
Rnor_6.0876,618,937 - 76,619,913NCBIRnor6.0
Rnor_6.01224,207,674 - 24,207,905NCBIRnor6.0
Rnor_5.01226,204,977 - 26,205,208UniSTSRnor5.0
RGSC_v3.41222,314,597 - 22,314,828UniSTSRGSC3.4
RGSC_v3.4874,643,445 - 74,644,421UniSTSRGSC3.4
Celera1222,922,992 - 22,923,225UniSTS
Celera124,359,958 - 4,361,111UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map12q12UniSTS
RH91194  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21221,193,622 - 21,195,182 (+)MAPPERmRatBN7.2
Rnor_6.01224,241,646 - 24,243,205NCBIRnor6.0
Rnor_5.01226,238,949 - 26,240,508UniSTSRnor5.0
RGSC_v3.41222,348,066 - 22,349,625UniSTSRGSC3.4
Celera1222,956,395 - 22,957,954UniSTS
Cytogenetic Map12q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC087262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC091503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF388529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000030497   ⟹   ENSRNOP00000031153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,769,991 - 26,904,296 (+)Ensembl
mRatBN7.2 Ensembl1221,133,408 - 21,267,725 (+)Ensembl
Rnor_6.0 Ensembl1224,180,937 - 24,315,373 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098638   ⟹   ENSRNOP00000088574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,826,831 - 26,900,663 (+)Ensembl
mRatBN7.2 Ensembl1221,190,263 - 21,267,725 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104382   ⟹   ENSRNOP00000078035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,848,064 - 26,900,663 (+)Ensembl
mRatBN7.2 Ensembl1221,211,411 - 21,267,725 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119935   ⟹   ENSRNOP00000083048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,769,961 - 26,900,663 (+)Ensembl
mRatBN7.2 Ensembl1221,133,406 - 21,263,011 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158458   ⟹   ENSRNOP00000100363
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,850,477 - 26,900,663 (+)Ensembl
RefSeq Acc Id: NM_001100475   ⟹   NP_001093945
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,769,991 - 26,904,296 (+)NCBI
mRatBN7.21221,133,408 - 21,267,725 (+)NCBI
Rnor_6.01224,180,937 - 24,315,373 (+)NCBI
Rnor_5.01226,178,145 - 26,312,676 (+)NCBI
RGSC_v3.41222,287,861 - 22,422,163 (+)RGD
Celera1222,895,802 - 23,030,274 (+)RGD
Sequence:
RefSeq Acc Id: NM_001415756   ⟹   NP_001402685
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,769,947 - 26,904,367 (+)NCBI
mRatBN7.21221,133,364 - 21,267,796 (+)NCBI
RefSeq Acc Id: XM_006249099   ⟹   XP_006249161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,847,953 - 26,904,367 (+)NCBI
mRatBN7.21221,211,402 - 21,267,796 (+)NCBI
Rnor_6.01224,259,296 - 24,313,361 (+)NCBI
Rnor_5.01226,178,145 - 26,312,676 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006249100   ⟹   XP_006249162
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,826,531 - 26,904,367 (+)NCBI
mRatBN7.21221,189,958 - 21,267,796 (+)NCBI
Rnor_6.01224,238,278 - 24,313,361 (+)NCBI
Rnor_5.01226,178,145 - 26,312,676 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598252   ⟹   XP_017453741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,850,478 - 26,904,367 (+)NCBI
mRatBN7.21221,213,903 - 21,267,785 (+)NCBI
Rnor_6.01224,261,168 - 24,313,361 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598253   ⟹   XP_017453742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,850,478 - 26,904,367 (+)NCBI
mRatBN7.21221,213,903 - 21,267,796 (+)NCBI
Rnor_6.01224,261,168 - 24,313,361 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039089055   ⟹   XP_038944983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,850,478 - 26,904,367 (+)NCBI
mRatBN7.21221,213,903 - 21,267,796 (+)NCBI
RefSeq Acc Id: XM_063271032   ⟹   XP_063127102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,769,868 - 26,904,367 (+)NCBI
RefSeq Acc Id: XM_063271033   ⟹   XP_063127103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,769,868 - 26,904,367 (+)NCBI
RefSeq Acc Id: XM_063271034   ⟹   XP_063127104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,826,528 - 26,904,367 (+)NCBI
RefSeq Acc Id: XM_063271035   ⟹   XP_063127105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,873,015 - 26,904,367 (+)NCBI
RefSeq Acc Id: XM_063271036   ⟹   XP_063127106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,867,778 - 26,904,367 (+)NCBI
RefSeq Acc Id: NP_001093945   ⟸   NM_001100475
- Peptide Label: isoform 1
- UniProtKB: A6J0C8 (UniProtKB/TrEMBL),   A0A8I6GA90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249162   ⟸   XM_006249100
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AA26 (UniProtKB/TrEMBL),   A6J0C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249161   ⟸   XM_006249099
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y6T0 (UniProtKB/TrEMBL),   A6J0C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453741   ⟸   XM_017598252
- Peptide Label: isoform X1
- UniProtKB: A6J0C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453742   ⟸   XM_017598253
- Peptide Label: isoform X1
- UniProtKB: A6J0C9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000031153   ⟸   ENSRNOT00000030497
RefSeq Acc Id: XP_038944983   ⟸   XM_039089055
- Peptide Label: isoform X1
- UniProtKB: A6J0C9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078035   ⟸   ENSRNOT00000104382
Ensembl Acc Id: ENSRNOP00000088574   ⟸   ENSRNOT00000098638
Ensembl Acc Id: ENSRNOP00000083048   ⟸   ENSRNOT00000119935
RefSeq Acc Id: NP_001402685   ⟸   NM_001415756
- Peptide Label: isoform 2
- UniProtKB: A0A8I6GA90 (UniProtKB/TrEMBL),   G3V8Y8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127102   ⟸   XM_063271032
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GA90 (UniProtKB/TrEMBL),   G3V8Y8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127103   ⟸   XM_063271033
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GA90 (UniProtKB/TrEMBL),   G3V8Y8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127104   ⟸   XM_063271034
- Peptide Label: isoform X4
- UniProtKB: A6J0C9 (UniProtKB/TrEMBL),   A0A8I6AA26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127106   ⟸   XM_063271036
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063127105   ⟸   XM_063271035
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000100363   ⟸   ENSRNOT00000158458
Protein Domains
ENTH   I/LWEQ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V8Y8-F1-model_v2 AlphaFold G3V8Y8 1-1030 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698551
Promoter ID:EPDNEW_R9076
Type:initiation region
Name:Hip1_1
Description:huntingtin interacting protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01224,180,986 - 24,181,046EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620305 AgrOrtholog
BioCyc Gene G2FUF-19623 BioCyc
Ensembl Genes ENSRNOG00000001448 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030497 ENTREZGENE
  ENSRNOT00000030497.6 UniProtKB/TrEMBL
  ENSRNOT00000098638 ENTREZGENE
  ENSRNOT00000098638.2 UniProtKB/TrEMBL
  ENSRNOT00000104382 ENTREZGENE
  ENSRNOT00000104382.2 UniProtKB/TrEMBL
  ENSRNOT00000119935 ENTREZGENE
  ENSRNOT00000119935.2 UniProtKB/TrEMBL
  ENSRNOT00000158458 ENTREZGENE
  ENSRNOT00000158458.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.1700 UniProtKB/TrEMBL
  1.25.40.90 UniProtKB/TrEMBL
  6.10.250.920 UniProtKB/TrEMBL
  I/LWEQ domain UniProtKB/TrEMBL
InterPro ANTH UniProtKB/TrEMBL
  ENTH_VHS UniProtKB/TrEMBL
  Epsin-like_N UniProtKB/TrEMBL
  HIP1_clath-bd UniProtKB/TrEMBL
  I/LWEQ_dom_sf UniProtKB/TrEMBL
  ILWEQ UniProtKB/TrEMBL
  Sla2_fam UniProtKB/TrEMBL
NCBI Gene 192154 ENTREZGENE
PANTHER PTHR10407 UniProtKB/TrEMBL
  PTHR10407:SF14 UniProtKB/TrEMBL
Pfam ANTH UniProtKB/TrEMBL
  HIP1_clath_bdg UniProtKB/TrEMBL
  I_LWEQ UniProtKB/TrEMBL
PhenoGen Hip1 PhenoGen
PROSITE ENTH UniProtKB/TrEMBL
  I_LWEQ UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001448 RatGTEx
SMART ENTH UniProtKB/TrEMBL
  ILWEQ UniProtKB/TrEMBL
Superfamily-SCOP ENTH_VHS UniProtKB/TrEMBL
  SSF109885 UniProtKB/TrEMBL
UniProt A0A8I5Y6T0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AA26 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GA90 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LGQ7_RAT UniProtKB/TrEMBL
  A6J0C8 ENTREZGENE, UniProtKB/TrEMBL
  A6J0C9 ENTREZGENE, UniProtKB/TrEMBL
  A6J0D0_RAT UniProtKB/TrEMBL
  G3V8Y8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Hip1  huntingtin interacting protein 1      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Hip1  huntingtin interacting protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL