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Gene: Pik3c2g (phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma) Rattus norvegicus

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Symbol:

Pik3c2g

Name:

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma

RGD ID:

620231

Description:

Enables 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in phosphatidylinositol-3-phosphate biosynthetic process. Located in nuclear envelope. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LRRG00132; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; phosphoinositide 3-Kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI3K-C2-gamma; PI3K-C2gamma; ptdIns-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	174,215,527 - 174,583,378 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	174,215,527 - 174,581,705 (+)	Ensembl				GRCr8
mRatBN7.2	4	172,483,752 - 172,851,623 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	172,484,345 - 172,850,544 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	178,779,339 - 179,145,536 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	174,563,498 - 174,929,713 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	173,184,038 - 173,550,261 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	173,732,196 - 174,102,502 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	173,732,248 - 174,102,496 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	238,344,297 - 238,356,116 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	4	237,973,381 - 238,271,814 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	176,712,201 - 177,074,095 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	161,042,817 - 161,401,470 (+)	NCBI		Celera
RGSC_v3.1	4	176,957,324 - 177,319,218 (+)	NCBI
Cytogenetic Map	4	q44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

coronary artery disease (ISO)

esophageal atresia/tracheoesophageal fistula (ISO)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

atazanavir sulfate (ISO)

benzo[a]pyrene (ISO)

Benzo[ghi]perylene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium dichloride (EXP)

cantharidin (ISO)

CGP 52608 (ISO)

chenodeoxycholic acid (ISO)

chlorpyrifos (ISO)

cobalt dichloride (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

deoxycholic acid (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (EXP)

fenofibrate (EXP)

flutamide (EXP)

fructose (EXP)

glycochenodeoxycholic acid (ISO)

glycocholic acid (ISO)

glycodeoxycholic acid (ISO)

isotretinoin (ISO)

methoxychlor (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-Nitrosopyrrolidine (ISO)

nefazodone (ISO)

nickel atom (ISO)

nickel dichloride (EXP)

O-methyleugenol (ISO)

okadaic acid (ISO)

oleanolic acid (EXP)

paracetamol (ISO)

paraquat (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

pirinixic acid (EXP,ISO)

pregnenolone 16alpha-carbonitrile (EXP,ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

tartrazine (ISO)

tetrachloromethane (EXP)

tetracycline (ISO)

thioacetamide (EXP)

tipifarnib (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

triphenyl phosphate (EXP)

valdecoxib (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (IBA)

chemotaxis (IEA,ISO)

host-mediated perturbation of viral process (IEA)

lipid metabolic process (IEA)

phosphatidylinositol 3-kinase/protein kinase B signal transduction (IBA)

phosphatidylinositol phosphate biosynthetic process (IEA)

phosphatidylinositol-3-phosphate biosynthetic process (IBA,IDA,IEA,ISO)

phosphatidylinositol-mediated signaling (IBA)

RNA-templated DNA biosynthetic process (IEA)

Cellular Component

cytoplasm (IBA)

membrane (IEA,ISO)

nuclear envelope (IDA)

plasma membrane (IBA)

Molecular Function

1-phosphatidylinositol 4-kinase activity (IDA)

1-phosphatidylinositol-3-kinase activity (IBA,IDA,IEA,ISO)

1-phosphatidylinositol-4-phosphate 3-kinase activity (IBA,IDA,IEA,ISO)

ATP binding (IEA)

kinase activity (IEA)

nucleotide binding (IEA)

phosphatidylinositol binding (IEA)

phosphatidylinositol kinase activity (IEA)

RNA-directed DNA polymerase activity (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

inositol phosphate metabolic pathway (IEA)

phosphatidylinositol 3-kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Association of the PIK3C2G gene polymorphisms with type 2 DM in a Japanese population.	Daimon M, etal., Biochem Biophys Res Commun. 2008 Jan 18;365(3):466-71. doi: 10.1016/j.bbrc.2007.10.180. Epub 2007 Nov 6.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	A novel class II phosphoinositide 3-kinase predominantly expressed in the liver and its enhanced expression during liver regeneration.	Ono F, etal., J Biol Chem 1998 Mar 27;273(13):7731-6.
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12464394	PMID:12482897	PMID:15362046	PMID:19376974	PMID:20536348

Genomics

Comparative Map Data

Pik3c2g
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	174,215,527 - 174,583,378 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	174,215,527 - 174,581,705 (+)	Ensembl				GRCr8
mRatBN7.2	4	172,483,752 - 172,851,623 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	172,484,345 - 172,850,544 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	178,779,339 - 179,145,536 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	174,563,498 - 174,929,713 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	173,184,038 - 173,550,261 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	173,732,196 - 174,102,502 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	173,732,248 - 174,102,496 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	238,344,297 - 238,356,116 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	4	237,973,381 - 238,271,814 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	176,712,201 - 177,074,095 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	161,042,817 - 161,401,470 (+)	NCBI		Celera
RGSC_v3.1	4	176,957,324 - 177,319,218 (+)	NCBI
Cytogenetic Map	4	q44	NCBI

PIK3C2G
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	18,242,961 - 18,726,817 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	18,242,960 - 18,648,416 (+)	Ensembl			hg38	GRCh38
GRCh37	12	18,414,452 - 18,801,350 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	18,305,741 - 18,692,617 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	18,305,740 - 18,692,615	NCBI
Celera	12	23,559,670 - 23,946,872 (+)	NCBI		Celera
Cytogenetic Map	12	p12.3	NCBI
HuRef	12	18,182,567 - 18,569,771 (+)	NCBI		HuRef
CHM1_1	12	18,379,684 - 18,766,393 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	18,118,895 - 18,602,723 (+)	NCBI		T2T-CHM13v2.0

Pik3c2g
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	139,591,070 - 139,915,010 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	139,564,219 - 139,915,010 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	139,614,072 - 139,969,284 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	139,587,221 - 139,969,284 (+)	Ensembl			mm10	GRCm38
MGSCv37	6	139,664,380 - 139,917,805 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv37	6	139,562,593 - 139,605,759 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	139,678,267 - 139,931,692 (+)	NCBI		MGSCv36	mm8
Celera	6	142,714,228 - 143,033,452 (+)	NCBI		Celera
Cytogenetic Map	6	G2	NCBI
cM Map	6	69.7	NCBI

Pik3c2g
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	14,454,377 - 14,764,558 (+)	Ensembl
ChiLan1.0	NW_004955413	14,454,376 - 14,764,323 (+)	NCBI	ChiLan1.0	ChiLan1.0

PIK3C2G
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	23,702,676 - 24,088,671 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	23,699,436 - 24,085,421 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	18,258,487 - 18,644,464 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	18,664,539 - 19,030,778 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	18,664,631 - 19,030,493 (+)	Ensembl			panPan2	panpan1.1

PIK3C2G
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	28,446,629 - 28,818,198 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	28,424,899 - 28,796,902 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	17,634,256 - 18,004,900 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	28,777,707 - 29,148,879 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	28,777,942 - 29,120,607 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	28,624,760 - 28,982,990 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	28,617,093 - 28,982,011 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	17,346,838 - 17,712,725 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pik3c2g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	89,681,373 - 90,001,143 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936548	7,604,404 - 7,856,872 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936548	7,604,272 - 7,923,984 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PIK3C2G
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	54,474,622 - 54,849,512 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	54,474,623 - 54,849,520 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	57,747,735 - 58,146,257 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PIK3C2G
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	18,099,328 - 18,500,030 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	18,118,717 - 18,499,985 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666069	16,715,340 - 17,100,145 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pik3c2g
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	19,876,933 - 20,212,907 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624752	19,878,095 - 20,212,872 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pik3c2g
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	9,599,769 - 9,895,190 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pik3c2g
1859 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	16
Count of miRNA genes:	15
Interacting mature miRNAs:	16
Transcripts:	ENSRNOT00000041499
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	146370897	184426481	Rat
724558	Plsm2	Polydactyly-luxate syndrome (PLS) morphotypes QTL 2		0.0003	hindlimb integrity trait (VT:0010563)	hind foot phalanges count (CMO:0001949)	4	134095016	179095016	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	146370897	184426481	Rat
6478757	Anxrr44	Anxiety related response QTL 44		0.01087	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
1358364	Sradr4	Stress Responsive Adrenal Weight QTL 4	4.92		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	131384565	176384565	Rat
1331738	Bp209	Blood pressure QTL 209	2.979		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	140059299	181024663	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
1298524	Oia8	Oil induced arthritis QTL 8			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
10053718	Scort25	Serum corticosterone level QTL 25	2.15	0.0097	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	157292416	184426481	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	147299608	184426481	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
6478782	Anxrr52	Anxiety related response QTL 52		0.02091	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
6478720	Alc23	Alcohol consumption QTL 23		0.00509	drinking behavior trait (VT:0001422)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	155834926	184426481	Rat
6478785	Anxrr53	Anxiety related response QTL 53		0.01397	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	100752691	179366077	Rat
1581566	Eae21	Experimental allergic encephalomyelitis QTL 21	6.2		body mass (VT:0001259)	maximum body weight loss to initial body weight ratio (CMO:0001400)	4	137447185	182447185	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	4	137430611	182430611	Rat
6478728	Anxrr36	Anxiety related response QTL 36		0.01061	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
634342	Cia24	Collagen induced arthritis QTL 24	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	148121375	176967367	Rat
6478733	Anxrr37	Anxiety related response QTL 37		0.00095	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
61362	Oia2	Oil induced arthritis QTL 2		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
6478737	Anxrr38	Anxiety related response QTL 38		0.00159	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	155834926	184426481	Rat
2293659	Bmd35	Bone mineral density QTL 35	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	4	160623982	184426481	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat

Markers in Region

D4Got275

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	4	174,405,942 - 174,406,184 (+)	Marker Load Pipeline
mRatBN7.2	4	172,674,773 - 172,675,015 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	173,928,221 - 173,928,462	NCBI	Rnor6.0
Rnor_5.0	4	238,164,878 - 238,165,119	UniSTS	Rnor5.0
RGSC_v3.4	4	176,903,911 - 176,904,152	UniSTS	RGSC3.4
Celera	4	161,228,714 - 161,228,955	UniSTS
Cytogenetic Map	4	q44	UniSTS

BE113549

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	172,486,558 - 172,486,715 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	173,734,462 - 173,734,618	NCBI	Rnor6.0
Rnor_5.0	4	237,975,595 - 237,975,751	UniSTS	Rnor5.0
RGSC_v3.4	4	176,714,415 - 176,714,571	UniSTS	RGSC3.4
Celera	4	161,045,031 - 161,045,187	UniSTS
RH 3.4 Map	4	1031.7	UniSTS
Cytogenetic Map	4	q44	UniSTS

RH137861

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	172,522,615 - 172,522,754 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	173,770,513 - 173,770,651	NCBI	Rnor6.0
Rnor_5.0	4	238,011,653 - 238,011,791	UniSTS	Rnor5.0
RGSC_v3.4	4	176,750,473 - 176,750,611	UniSTS	RGSC3.4
Celera	4	161,081,066 - 161,081,204	UniSTS
RH 3.4 Map	4	1033.6	UniSTS
Cytogenetic Map	4	q44	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	11	56	127	86	90	59	37	59	6	253	117	7	114	58	90	31	16	16

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763348	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005503143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010065609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB009636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC096930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY539883	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000041499 ⟹ ENSRNOP00000043855

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	174,215,527 - 174,581,705 (+)	Ensembl
mRatBN7.2 Ensembl	4	172,484,345 - 172,850,544 (+)	Ensembl
Rnor_6.0 Ensembl	4	173,732,248 - 174,102,496 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078963 ⟹ ENSRNOP00000071128

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	174,453,845 - 174,469,104 (+)	Ensembl
mRatBN7.2 Ensembl	4	172,722,676 - 172,737,935 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000127385 ⟹ ENSRNOP00000110358

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	174,215,527 - 174,581,705 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000135254 ⟹ ENSRNOP00000102795

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	174,215,527 - 174,581,705 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000166248 ⟹ ENSRNOP00000101984

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	174,215,527 - 174,581,705 (+)	Ensembl

RefSeq Acc Id:

NM_053923 ⟹ NP_446375

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	174,215,527 - 174,581,708 (+)	NCBI
mRatBN7.2	4	172,484,345 - 172,850,547 (+)	NCBI
Rnor_6.0	4	173,732,248 - 174,102,499 (+)	NCBI
Rnor_5.0	4	237,973,381 - 238,271,814 (+)	NCBI
Rnor_5.0	4	238,344,297 - 238,356,116 (+)	NCBI
RGSC_v3.4	4	176,712,201 - 177,074,095 (+)	RGD
Celera	4	161,042,817 - 161,401,470 (+)	RGD

Sequence:

show sequence

GAGGAAGCAAAGACCGGGCAAAACACATGAAGGAAAATTTGGAACTTCTTTTATAATATCAACA
AGACATTTGGGGCCAAATAAATCCTCTCCGTTACACAAAACCAAAAATGGCATACAATTGGCAA
ACAGAGCCAAACCGTGCTGAACCACAGGAAGGTGGACATGATCACCAGCAGTGTCACCATGCAG
ACCAGCACCTTTCTTCCAGGCAAGTCAGGTTGGGTTTTGATCAGCTTGTGGAAGAGCTCAGTAA
CAAAACTCCACTGCCTGAGGATGAAAAAGAAGGCACGTGTTTTGTACCAGATACACCAAACTTG
GATTCAAAATGGCAATCCATATATGGACCCCACCCAAGGCACTTCAATGAATTCACTTCTCAGA
GTCCCCACTTCTCCCAGCTTCCTTTTGGAAAAGCATCAGCCATTGGTTTTAATCCTGCTGTATT
ACCTGCACATCAGTTCATTCATGAGGGAGCCTCCTGGAGAAATCCCACAAGAAAATATCATGGT
GGTGAGGATCCCAGGTTCAGTGCTCTAACTCCGTCATCCACTGGCTTGGATAAATGTCATCAAC
AAGGACAATCAGGGACCGAACATTGTAACTATTATGTGGAACCTGAAAACAATGTTCCCCATCA
TTATTCACCCTACTCAATGGACTCCATACCCGATAGTGAGGAAAAAGGAAGTGGAGATGCGGAT
CTTGTAGAACCTTCTCTGGTGTTCTCTAAAGACTCCTTTCTACCCAGGGCATCGGAGAACATGT
CAGTGGAAAGCACAGAGCCCATTGGTTGCCCCCTTGAAATAGTTGAAGCACCCCAAGGGAGTAA
CAAGAGCCTCGCCTCCTTTTGCAACAATGTAACAAAAATAAGAGGACTATATCATGCAAGTGAC
ACTAATTCCAATTCCGGAAAGATCTGGGCCATCACCACAGCCTATCCATCTCGGCTCTTCGCTG
ACACCCAGTTCAGAGTTAAAATTTCCACTGATAACTCGGCACAACTTCTTCTTCTTAAGCCACC
CGCTAATTATCTTGTCAAAGACCTAATTGCCGAAATTCTACTTTTATGTGCAAATGAGCAGCTT
TCCCCCAAAGAGTATCTTCTAAGTATATGCGGTTCTGAGGAATTTTTACAGACGGATCACTGTC
TAGGGAGCCACAAAATATTTCAGAAAAGTAAATCTGTCATTCAACTCCATCTCCAGAGAAGCAG
GGACACTCCAGGAAAATTATCCCGGAAGAGGGATGATGACCGCAGTCGGGTCCATCTGAACCAA
CTTCTAGAATTTACACATATTTGGAAAATATCCAGACAATGCCTCTCCACAGTAATGAAAAGCT
ACAACCTCCATGTCGAGCACCTGTTGAAAACCCAGGAAGATGTGGAGGAGAAACCTCTGTCATC
CATGTTTTCCTGTGGCCGACACCCTCCTCAGCCACATGGGAATGACATTATTGAAGATGTTAGA
AACATATGCAGTGTTCTGGGGTGTATTGAAACCAAACAAGTTTCAGATGCAGTAAAAGAACTAA
CTCTAATTCTGCAGAGACCATCACAGAATTTTCATCAGAATTCAGAGACTTCAAAAAAAGGCTT
CATAGAGAACGTGACATCGGAACTGTCGAGGTCCCTCCATCAGCTGGTTGACGTGTACTGCAGT
AGCTTTTGTACAGATTTCCGGCCTGCGCGCGCACCTGGAGGCGTCTCCCGCGACCACGCTGGGC
TCCACTCCCACCTGAGCTTCACGGTGTGTTCCCTGCACAATGTTCCAGAAACTTGGGCACACAG
CTACAAAGCATTTTCATTTTCCTGCTGGCTCACATATGCTGGGAAGAAGCTGTGCCAAGTGAAA
AGCTGCAGATCCCTGCCAGTCACAAAGTCATTCTCTTTTTCGGTGAACTGGAATGAAATAATCA
ATTTTCCTCTTGAGATAAAGTCACTTCCAAGAGAATCCATGCTCGTTATAAAGCTGTTTGGGAT
TGACAGTGCCACCCACAGCGCAAATCTGCTGGCCTGGACCTGCCTTCCACTATTTCCAAAAGAA
AAGTCTCCGCTGGGGTCTAGGCTTCTCAGCATGACACTACAGAGTGAGCCTCCTATAGAAATGA
TGGCTCCAGGAGTATGGGATGGGAGCCAGCCTACCCCACTGACCCTGCAGATAGATTTTCCAGC
TGCCACGTGGGAGTACGTGAAACCTGAGACTGAAGAGAACAGAACTGACCACCAAGAGCCTCCA
AGAGAGTGTTTAAAACACATCGCCAGACTCTCCCAAAAGCAGCCTCCCTTGCTACTTTCTGTGG
AAAAGAGGAGATATTTGTGGTTTTATCGTTTCTACTGCAACAATGAGAACTCCTCTCTCCCTCT
GGTCTTGGGCAGCGCCCCTGGTTGGGATGAAGGGACAGTTTCGGAAATGCATGCCGTCTTGAGA
AGGTGGACATTTTCCCATCCGTTGGAAGCTCTTGGCCTTTTGACTTCCAGGTTTCCAGACCAAG
ACATTCGTGAAGTTGCCGTTCAACAGTTAGACAACTTCTTGACCGATGAGCTGCTGGACTGCCT
CCCACAGCTAGTTCAGGCTGTCAAGTTTGAGTGGAGTCTCGAAAGTCCCTTGGTGGAACTCCTG
CTTCATCGATCCTTGCAAAGCATCCGAGTGGCTCACCGCCTGTTCTGGCTGCTGCGGGATGCAC
AAGGTGAAGACTACTTTAAAAGCTGGTACCAGGAGCTTTTGGCCGCTCTCCAGTTCTGTGCAGG
AGAAGCCCTGATCGAAGAGCTTTCCAAAGAGCAGAAACTTGTCAAACTCCTGGGTGATATTGGA
GAAAAAGTGAAGTCGGCTGGCGATGCTCAGAGAAAGGATGTGCTAAAGAAGGAGATTGGCAGTC
TAGAAGAATTCTTTAAAGATATAAAGACTTGCCATCTTCCTCTGAACCCGGCCCTGTGCGTAAA
AGGAATTGATCGGGATGCATGTTCATATTTCACATCTAATGCCTTGCCATTGAAGATCACTTTC
ATCAATGCTAATCCAATGGGCAAAAATATCAGTGTTATTTTTAAGGCCGGCGACGATCTTCGGC
AGGATATGCTTGTTCTGCAGATTATTCAAGTGATGGACAACGTTTGGCTTCAGGAGGGCCTCGA
TATGCAAATGATCATTTATGGATGTCTAGCCACAGGAAAGGCTCAAGGATTCATAGAGATGGTG
CCTGATGCTGTAACGCTTGCCAAGATCCATCTGCACTCTGGGCTGATAGGACCCCTGAAAGAAA
ACACCATCAAGAAGTGGTTCAGTCAGCACAACCACTTAAAGGAAGATTATGAAAAGGCCTTGAG
GAACTTTTTTTACTCTTGTGCTGGCTGGTGTGTGGTGACATTCATCTTGGGAGTCTGTGACCGA
CATAATGACAATATCATGCTGACAAAGTCAGGCCACATGTTTCATATTGACTTTGGAAAATTCT
TGGGTCACGCACAAACATTTGGCGGTATAAAAAGGGACCGAGCGCCTTTCATTTTTACTTCAGA
GATGGAGTACTTTATTACGGAGGGTGGGAAAAACACACAGCATTTTCAAGACTTCGTGGAACTC
TGCTGCAGAGCCTACAACATTGTGAGGAAGCACAGCCAACTGCTCCTGAGCCTTCTAGAAATGA
TGCTGCATGCCGGGCTTCCTGAGCTGAGGGGGATTGAAGACCTGAAATACGTACACGACAATCT
CCGGCCACAAGACACAGACCTGGAAGCCACAAGTCATTTTACCACGAAGATAAAGCAGAGTCTG
GAGTGCTTCCCAGTTAAACTGAATAACCTGATCCACACGCTTGCACAGATGCCAGCCTTCAGCC
TTGCCAGACCTGCCCCTCAGACTCCTCCCCAGGAGTGCTGCGTCCTGAATAAAACCAGGACAAT
TCAGAGAGTCACAATTTTAGGGTTCAGCAAGACACACAGCAACCTGTACCTGATCGAGGTGACA
CGCAGCGACAACAGGAAAAACCTGGCCAAAAAGTCCTTCGAGCAGTTTTACAGACTTCACAGCC
AGATTCAGAAGCAGTTCCCCTTGTTGACTCTCCCAGAGTTTCCTCACTGGTGGCATCTACCTTT
CACAGACTCGCACCATGAGAGAATCCGAGATCTGAGTCACTACGTGGAACAGGTGCTGCACGGA
TCTTACGAAGTCGCAAACAGTGATTGTGTACTCAGTTTTTTTCTCTCTGAACATATACAACAGA
CCCTTGAAGACTCTCCATTTGTGGACCCAGGTGACCATTCTCCAGACAAGAGCCCCCAGGTGCA
GTTGCTGATGACCTATGAGGACACAAAGCTCACCATCCTAGTGAAACACTTGAAAAACATCCAT
CTCCCAGATGGCTCAGCGCCCAGCGCACATGTTGAAATTTATCTTCTGCCACATCCCAGTGAAG
TTCGCAGGAAGAAAACAAAGTGCGTTCCAAAATGCACTGACCCAACTTACAATGAAATTGTGGT
ATATGATGACGTCTCAGGACTTCAGGGACATGTTTTAATGCTCATTGTGAAGAGCAAAACTGTA
TTTGTGGGAGCGGTTAACATTCAGCTCTGCAGTGTTCCCCTCAATGAAGAAAAGTGGTACCCAT
TAGGGAACAGTATCATCTGACCAATGCCATGAATGTATGCATTATTGATTAAGTACTTGTGTGT
TTTCAGCTTCCATTTCCCCTATAGCATACACAAGGCATCTTTCTTGCGGAAGATGGCTTGGAGC
AGTGGTTCTCACTCAGCGTCCCTAACACTGCGACCCTTTAATACAATTCCTGGTGATTGTAGTG
ACCCAAACCACAAAATTATTTTAGTTGCTATTTCACAACTGTAATTTTGACACGGTTATGAATT
GCAATGTATATATCTGATCTACAGGATACCTACTATTCGACCCCTGTGATAAAAGGGTCATTGG
ACAATCCCAAAGGGTCATGACTCATGGGTTGAGAACCACAGGCTTAGAGTGGTCACAGAAGAAG
CAGATCAAAATCAGTCTTTTGTAGCTCTTTCTTCTCTACCTTCTCCTTATTTTCTTATCATATT
TTCTCCTTGGAATATTCATCATGGAAAATCCCATATGCAAAGTCATGAAAGAATGATTCATTTA
ATATGCATTTTTGAATCAAACTAAGTTCATGTCTTGCCTTAATTGCTTGTTGAGGTCAAAATTA
TACTTTTAGGGTGTTTTCTAAAGCTAGGAGAAGCTCATGTAAGGGTTAAGAATATTTGCAATAT
ATTTCAAAAGTTAAATATGTGTACAAGCCACATATCTAGTCATGATTGAATTTATTGAGAGAAT
TGGTGATCTCCAACCATGTGCTATAATTTTTCTATCAAAAAAAAATCCCTAAGATTTTTCTATT
GCATAGATTTTTTTTCTTTAAGAATTTCATGCATGTATATAGTGCTTTCGTTATTGTAGCTTCT
CTCTTTTTTAGTTGTCCCCACACCCATCAACAACTGTTCTTCTCTAAAACTCCTGTATTCCTGT
GGGGAGTTTTATTTTTAAGATGGGCATCAAACTATATATCCCAGCTGACCTAGAGCTTGCTATG
TTGACCAGGTGGGCCCCAAATCACAGTGGTCCTCCTGCCTCTGTTTCCCGACCGCTAAGGTTCC
AGGTCATTGGATCTTGTCTGTAATTTTTAAGTTCAGTTCTTAGAATTTGATATTGATCAATCCA
GTGTCATTGTGTCTTCCAGCCTCGGTCATGTTCACACCTTAAATCTTATTAATCTCCAAACCCA
AAATATCCAACTTTTAAGTTCACCATTTAAAACGCCTCTTTGCGTGTTAAATACTCTCACTGCA
CTTGAACCAACACCTTGTGTTCGCACGGACCAGATAGATGATCTCACAGTTTGTCACCTGTGTA
ACAGGCAAACCCAGAGGACGCCTCCAAGATAATCAAACTGGAGGTTTCAAAAATAAAACATCTG
CCATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039106948 ⟹ XP_038962876

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	174,252,810 - 174,583,378 (+)	NCBI
mRatBN7.2	4	172,483,758 - 172,851,623 (+)	NCBI

RefSeq Acc Id:

XR_005503143

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	174,252,810 - 174,371,605 (+)	NCBI
mRatBN7.2	4	172,483,752 - 172,640,505 (+)	NCBI

RefSeq Acc Id:

XR_010065609

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	174,252,810 - 174,371,677 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_446375	(Get FASTA)	NCBI Sequence Viewer
	XP_038962876	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAS66223	(Get FASTA)	NCBI Sequence Viewer
	BAA25634	(Get FASTA)	NCBI Sequence Viewer
	EDM01564	(Get FASTA)	NCBI Sequence Viewer
	EDM01565	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000043855
GenBank Protein	O70173	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_446375 ⟸ NM_053923

- UniProtKB:

O70173 (UniProtKB/Swiss-Prot), D3ZE56 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAYNWQTEPNRAEPQEGGHDHQQCHHADQHLSSRQVRLGFDQLVEELSNKTPLPEDEKEGTCFV
PDTPNLDSKWQSIYGPHPRHFNEFTSQSPHFSQLPFGKASAIGFNPAVLPAHQFIHEGASWRNP
TRKYHGGEDPRFSALTPSSTGLDKCHQQGQSGTEHCNYYVEPENNVPHHYSPYSMDSIPDSEEK
GSGDADLVEPSLVFSKDSFLPRASENMSVESTEPIGCPLEIVEAPQGSNKSLASFCNNVTKIRG
LYHASDTNSNSGKIWAITTAYPSRLFADTQFRVKISTDNSAQLLLLKPPANYLVKDLIAEILLL
CANEQLSPKEYLLSICGSEEFLQTDHCLGSHKIFQKSKSVIQLHLQRSRDTPGKLSRKRDDDRS
RVHLNQLLEFTHIWKISRQCLSTVMKSYNLHVEHLLKTQEDVEEKPLSSMFSCGRHPPQPHGND
IIEDVRNICSVLGCIETKQVSDAVKELTLILQRPSQNFHQNSETSKKGFIENVTSELSRSLHQL
VDVYCSSFCTDFRPARAPGGVSRDHAGLHSHLSFTVCSLHNVPETWAHSYKAFSFSCWLTYAGK
KLCQVKSCRSLPVTKSFSFSVNWNEIINFPLEIKSLPRESMLVIKLFGIDSATHSANLLAWTCL
PLFPKEKSPLGSRLLSMTLQSEPPIEMMAPGVWDGSQPTPLTLQIDFPAATWEYVKPETEENRT
DHQEPPRECLKHIARLSQKQPPLLLSVEKRRYLWFYRFYCNNENSSLPLVLGSAPGWDEGTVSE
MHAVLRRWTFSHPLEALGLLTSRFPDQDIREVAVQQLDNFLTDELLDCLPQLVQAVKFEWSLES
PLVELLLHRSLQSIRVAHRLFWLLRDAQGEDYFKSWYQELLAALQFCAGEALIEELSKEQKLVK
LLGDIGEKVKSAGDAQRKDVLKKEIGSLEEFFKDIKTCHLPLNPALCVKGIDRDACSYFTSNAL
PLKITFINANPMGKNISVIFKAGDDLRQDMLVLQIIQVMDNVWLQEGLDMQMIIYGCLATGKAQ
GFIEMVPDAVTLAKIHLHSGLIGPLKENTIKKWFSQHNHLKEDYEKALRNFFYSCAGWCVVTFI
LGVCDRHNDNIMLTKSGHMFHIDFGKFLGHAQTFGGIKRDRAPFIFTSEMEYFITEGGKNTQHF
QDFVELCCRAYNIVRKHSQLLLSLLEMMLHAGLPELRGIEDLKYVHDNLRPQDTDLEATSHFTT
KIKQSLECFPVKLNNLIHTLAQMPAFSLARPAPQTPPQECCVLNKTRTIQRVTILGFSKTHSNL
YLIEVTRSDNRKNLAKKSFEQFYRLHSQIQKQFPLLTLPEFPHWWHLPFTDSHHERIRDLSHYV
EQVLHGSYEVANSDCVLSFFLSEHIQQTLEDSPFVDPGDHSPDKSPQVQLLMTYEDTKLTILVK
HLKNIHLPDGSAPSAHVEIYLLPHPSEVRRKKTKCVPKCTDPTYNEIVVYDDVSGLQGHVLMLI
VKSKTVFVGAVNIQLCSVPLNEEKWYPLGNSII

hide sequence

Ensembl Acc Id:

ENSRNOP00000043855 ⟸ ENSRNOT00000041499

RefSeq Acc Id:	XP_038962876 ⟸ XM_039106948
- Peptide Label:	isoform X1
- UniProtKB:	O70173 (UniProtKB/Swiss-Prot), D3ZE56 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000071128 ⟸ ENSRNOT00000078963

Ensembl Acc Id:

ENSRNOP00000101984 ⟸ ENSRNOT00000166248

Ensembl Acc Id:

ENSRNOP00000110358 ⟸ ENSRNOT00000127385

Ensembl Acc Id:

ENSRNOP00000102795 ⟸ ENSRNOT00000135254

Protein Domains

C2 C2 PI3K-type PI3K-RBD PI3K/PI4K catalytic PIK helical PX Reverse transcriptase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O70173-F1-model_v2	AlphaFold	O70173	1-1505	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693476

Promoter ID:

EPDNEW_R3999

Type:

initiation region

Name:

Pik3c2g_1

Description:

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunittype 2 gamma

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	173,732,235 - 173,732,295	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620231	AgrOrtholog
BioCyc Gene	G2FUF-42549	BioCyc
Ensembl Genes	ENSRNOG00000034228	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000041499	ENTREZGENE
Gene3D-CATH	1.10.1070.11	UniProtKB/Swiss-Prot
	1.25.40.70	UniProtKB/Swiss-Prot
	2.60.40.150	UniProtKB/Swiss-Prot
	3.30.1520.10	UniProtKB/Swiss-Prot
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/Swiss-Prot
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4	UniProtKB/Swiss-Prot
InterPro	ARM-type_fold	UniProtKB/Swiss-Prot
	C2_dom	UniProtKB/Swiss-Prot
	C2_domain_sf	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Phox	UniProtKB/Swiss-Prot
	PI3/4_kinase_cat_dom	UniProtKB/Swiss-Prot
	PI3/4_kinase_cat_sf	UniProtKB/Swiss-Prot
	PI3/4_kinase_CS	UniProtKB/Swiss-Prot
	PI3K_accessory_sf	UniProtKB/Swiss-Prot
	PI3K_C2_dom	UniProtKB/Swiss-Prot
	PI3K_Ras-bd_dom	UniProtKB/Swiss-Prot
	PI_Kinase	UniProtKB/Swiss-Prot
	PInositide-3_kin_accessory_dom	UniProtKB/Swiss-Prot
	PX_dom_sf	UniProtKB/Swiss-Prot
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot
KEGG Report	rno:116720	UniProtKB/Swiss-Prot
NCBI Gene	116720	ENTREZGENE
PANTHER	PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT GAMMA	UniProtKB/Swiss-Prot
	PTHR10048	UniProtKB/Swiss-Prot
Pfam	PF00168	UniProtKB/Swiss-Prot
	PF00787	UniProtKB/Swiss-Prot
	PI3_PI4_kinase	UniProtKB/Swiss-Prot
	PI3K_C2	UniProtKB/Swiss-Prot
	PI3K_rbd	UniProtKB/Swiss-Prot
	PI3Ka	UniProtKB/Swiss-Prot
PhenoGen	Pik3c2g	PhenoGen
PROSITE	PI3_4_KINASE_1	UniProtKB/Swiss-Prot
	PI3_4_KINASE_2	UniProtKB/Swiss-Prot
	PI3_4_KINASE_3	UniProtKB/Swiss-Prot
	PI3K_C2	UniProtKB/Swiss-Prot
	PI3K_RBD	UniProtKB/Swiss-Prot
	PIK_HELICAL	UniProtKB/Swiss-Prot
	PS50004	UniProtKB/Swiss-Prot
	PS50195	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000034228	RatGTEx
SMART	PI3K_C2	UniProtKB/Swiss-Prot
	PI3Ka	UniProtKB/Swiss-Prot
	PI3Kc	UniProtKB/Swiss-Prot
	SM00239	UniProtKB/Swiss-Prot
	SM00312	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot
	SSF49562	UniProtKB/Swiss-Prot
	SSF54236	UniProtKB/Swiss-Prot
	SSF56112	UniProtKB/Swiss-Prot
	SSF64268	UniProtKB/Swiss-Prot
UniProt	A0A0G2JZP4_RAT	UniProtKB/TrEMBL
	A0ABK0LFG5_RAT	UniProtKB/TrEMBL
	A0ABK0LM58_RAT	UniProtKB/TrEMBL
	A0ABK0M5H6_RAT	UniProtKB/TrEMBL
	A6IMM4_RAT	UniProtKB/TrEMBL
	A6IMM5_RAT	UniProtKB/TrEMBL
	D3ZE56	ENTREZGENE, UniProtKB/TrEMBL
	O70173	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-10	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	Pik3c2g	phosphoinositide-3-kinase, class 2, gamma polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Pik3c2g	phosphoinositide-3-kinase, class 2, gamma polypeptide	Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-12-14	Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Pik3c2g	phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expression increases during liver regeneration with peak expression after the growth period	729517

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)