QTL: Cia24 (Collagen induced arthritis QTL 24) Rattus norvegicus

Symbol: Cia24
Name: Collagen induced arthritis QTL 24
Also known as: Cia13; Type II Collagen induced arthritis QTL 24
Trait: Joint/bone inflammation
Subtrait: type II collagen induced
Method: type II collagen was pepsin-solubilized from porcine (PII) and rat (RII) sternal cartilage samples; arthritis severity was determined by total score for each extremity; the 3 joints (interphalangeal, metatarsophalangeal, metacarpophalangeal) of each of the lateral 4 digits were scored 0 or 1 (0 5 no arthritis and 1 5 arthritis), and the wrist, mid-forepaw, ankle, and mid-foot were scored 04 (0 5 normal, 1 5 minimal swelling, 2 5 medium swelling, 3 5 severe swelling, and 4 5 ankylosis)
LOD Score: 4.5
P Value: Not Available
Variance: 7.6
Position
MapChrPositionStrandSource
RGSC Genome Assembly v5.04208,670,980 - 240,723,450 RGD
RGSC Genome Assembly v3.44149,304,432 - 179,854,843 RGD
Genome Assembly 3.14149,549,274 - 180,099,967 RGD
Cross Type: intercross
Strains Crossed: DA/Bkl BN/SsN 
Model
Launch Genome Browser (GBrowse)



Candidate Gene Status
Disease Annotations
Phenotype Annotations
References - curated
RGD Disease Portals

Region

Genes in Region (RGSC Genome Assembly v3.4)
Markers in Region (RGSC Genome Assembly v3.4)
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cia24
Genome Browser
QTL Registration

RGD Object Information
RGD ID: 634342
Created: 2003-08-29
Species: Rattus norvegicus
Last Modified: 2006-04-14
Status: ACTIVE