Ncan (neurocan) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ncan (neurocan) Rattus norvegicus
Analyze
Symbol: Ncan
Name: neurocan
RGD ID: 619941
Description: Predicted to enable calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; regulation of postsynapse organization; and skeletal system development. Predicted to act upstream of or within regulation of synapse structural plasticity. Located in perineuronal net. Is active in synapse. Orthologous to human NCAN (neurocan); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 245 kDa early postnatal core glycoprotein; chondroitin sulfate proteoglycan 3; Cspg3; LOC100911345; neurocan core protein; neurocan core protein-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,335,907 - 19,362,371 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1619,335,907 - 19,362,371 (+)EnsemblGRCr8
mRatBN7.21619,301,969 - 19,328,436 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,301,969 - 19,328,436 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1619,341,911 - 19,368,375 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,474,030 - 20,500,314 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,394,880 - 19,421,346 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01621,050,243 - 21,076,707 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,050,243 - 21,076,707 (+)Ensemblrn6Rnor6.0
Rnor_5.01620,900,031 - 20,926,495 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,785,175 - 19,811,651 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,490,684 - 19,517,054 (+)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Relative and absolute quantification of postsynaptic density proteome isolated from rat forebrain and cerebellum. Cheng D, etal., Mol Cell Proteomics. 2006 Jun;5(6):1158-70. doi: 10.1074/mcp.D500009-MCP200. Epub 2006 Feb 28.
2. Composition of perineuronal net extracellular matrix in rat brain: a different disaccharide composition for the net-associated proteoglycans. Deepa SS, etal., J Biol Chem. 2006 Jun 30;281(26):17789-800. Epub 2006 Apr 27.
3. Chondroitin sulfate proteoglycans in the developing central nervous system. I. cellular sites of synthesis of neurocan and phosphacan. Engel M, etal., J Comp Neurol 1996 Feb 26;366(1):34-43.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue. Grumet M, etal., J Biol Chem 1994 Apr 22;269(16):12142-6.
7. Sequence of rat alpha- and gamma-casein mRNAs: evolutionary comparison of the calcium-dependent rat casein multigene family. Hobbs AA and Rosen JM, Nucleic Acids Res 1982 Dec 20;10(24):8079-98.
8. Transient expression of juvenile-type neurocan by reactive astrocytes in adult rat brains injured by kainate-induced seizures as well as surgical incision. Matsui F, etal., Neuroscience 2002;112(4):773-81.
9. Chondroitin sulfate proteoglycans in the developing central nervous system. II. Immunocytochemical localization of neurocan and phosphacan. Meyer-Puttlitz B, etal., J Comp Neurol 1996 Feb 26;366(1):44-54.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. Characterization of the human neurocan gene, CSPG3. Prange CK, etal., Gene 1998 Oct 23;221(2):199-205.
14. Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain. Rauch U, etal., J Biol Chem 1992 Sep 25;267(27):19536-47.
15. GOA pipeline RGD automated data pipeline
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue. Tang X, etal., J Neurosci Res 2003 Feb 1;71(3):427-44.
Additional References at PubMed
PMID:1907283   PMID:7513709   PMID:8910306   PMID:9182584   PMID:11486035   PMID:12573465   PMID:15062856   PMID:15632090   PMID:15777769   PMID:18618668   PMID:21107918   PMID:25597185  
PMID:29476059  


Genomics

Comparative Map Data
Ncan
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,335,907 - 19,362,371 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1619,335,907 - 19,362,371 (+)EnsemblGRCr8
mRatBN7.21619,301,969 - 19,328,436 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,301,969 - 19,328,436 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1619,341,911 - 19,368,375 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,474,030 - 20,500,314 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,394,880 - 19,421,346 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01621,050,243 - 21,076,707 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,050,243 - 21,076,707 (+)Ensemblrn6Rnor6.0
Rnor_5.01620,900,031 - 20,926,495 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,785,175 - 19,811,651 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,490,684 - 19,517,054 (+)NCBICelera
Cytogenetic Map16p14NCBI
NCAN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381919,211,958 - 19,252,233 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1919,211,948 - 19,252,247 (+)Ensemblhg38GRCh38
GRCh371919,322,767 - 19,363,042 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,183,782 - 19,224,061 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341919,188,761 - 19,224,040NCBI
Celera1919,227,578 - 19,267,865 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,887,259 - 18,927,121 (+)NCBIHuRef
CHM1_11919,323,541 - 19,363,822 (+)NCBICHM1_1
T2T-CHM13v2.01919,349,378 - 19,389,681 (+)NCBIT2T-CHM13v2.0
Ncan
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,545,735 - 70,573,494 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,545,735 - 70,573,523 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38870,093,085 - 70,120,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,093,085 - 70,120,873 (-)Ensemblmm10GRCm38
MGSCv37872,616,984 - 72,644,743 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36873,022,074 - 73,049,799 (-)NCBIMGSCv36mm8
MGSCv36869,493,766 - 69,521,494 (-)NCBIMGSCv36mm8
Celera872,625,364 - 72,676,283 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Ncan
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,602,715 - 2,628,805 (-)Ensembl
ChiLan1.0NW_0049555242,602,767 - 2,628,771 (-)NCBIChiLan1.0ChiLan1.0
NCAN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22024,074,594 - 24,114,955 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11923,080,898 - 23,121,256 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,650,522 - 18,690,882 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,652,839 - 19,694,317 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,657,766 - 19,691,998 (+)EnsemblpanPan2panpan1.1
NCAN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12043,944,257 - 43,970,864 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2043,945,143 - 43,970,886 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2043,861,374 - 43,887,972 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02044,432,151 - 44,458,987 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,432,159 - 44,458,951 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,669,443 - 43,696,090 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,079,265 - 44,105,873 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,354,579 - 44,381,189 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ncan
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,642,791 - 202,669,871 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,189,838 - 2,218,987 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,190,593 - 2,218,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCAN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,638,808 - 58,674,130 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1258,638,808 - 58,669,757 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NCAN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,682,200 - 17,713,706 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,686,410 - 17,712,349 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660741,589,958 - 1,630,428 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ncan
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249082,102,445 - 2,125,820 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ncan
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11312,363,847 - 12,388,206 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ncan
126 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:278
Count of miRNA genes:170
Interacting mature miRNAs:209
Transcripts:ENSRNOT00000027768, ENSRNOT00000064308
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161574800625801629Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 7 18 146 54 53 24 28 24 6 126 66 128 23 59 29 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000064308   ⟹   ENSRNOP00000062123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1619,335,907 - 19,362,371 (+)Ensembl
mRatBN7.2 Ensembl1619,301,969 - 19,328,436 (+)Ensembl
Rnor_6.0 Ensembl1621,050,243 - 21,076,707 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092136   ⟹   ENSRNOP00000073142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1621,061,237 - 21,076,707 (+)Ensembl
RefSeq Acc Id: NM_031653   ⟹   NP_113841
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,335,907 - 19,362,371 (+)NCBI
mRatBN7.21619,301,969 - 19,328,436 (+)NCBI
Rnor_6.01621,050,243 - 21,076,707 (+)NCBI
Rnor_5.01620,900,031 - 20,926,495 (+)NCBI
RGSC_v3.41619,785,175 - 19,811,651 (+)RGD
Celera1619,490,684 - 19,517,054 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113841 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC15766 (Get FASTA)   NCBI Sequence Viewer  
  AAC37679 (Get FASTA)   NCBI Sequence Viewer  
  EDL90647 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000062123
GenBank Protein P55067 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113841   ⟸   NM_031653
- Peptide Label: precursor
- UniProtKB: P55067 (UniProtKB/Swiss-Prot),   G3V8R2 (UniProtKB/TrEMBL),   F1LNN7 (UniProtKB/TrEMBL),   A6KA90 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073142   ⟸   ENSRNOT00000092136
Ensembl Acc Id: ENSRNOP00000062123   ⟸   ENSRNOT00000064308
Protein Domains
C-type lectin   EGF-like   Ig-like   Ig-like V-type   Link   Sushi

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55067-F1-model_v2 AlphaFold P55067 1-1257 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700045
Promoter ID:EPDNEW_R10569
Type:single initiation site
Name:Ncan_1
Description:neurocan
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01621,050,217 - 21,050,277EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619941 AgrOrtholog
BioCyc Gene G2FUF-11754 BioCyc
Ensembl Genes ENSRNOG00000048036 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000064308 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.10.100.10 UniProtKB/Swiss-Prot
  Complement Module, domain 1 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro C-type_lectin-like UniProtKB/Swiss-Prot
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot
  C-type_lectin_CS UniProtKB/Swiss-Prot
  CTDL_fold UniProtKB/Swiss-Prot
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot
  Hyaluronan_bind_Proteoglycan UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  Link_dom UniProtKB/Swiss-Prot
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot
NCBI Gene 58982 ENTREZGENE
PANTHER AGGRECAN/VERSICAN PROTEOGLYCAN UniProtKB/Swiss-Prot
  NEUROCAN CORE PROTEIN UniProtKB/Swiss-Prot
Pfam EGF UniProtKB/Swiss-Prot
  Lectin_C UniProtKB/Swiss-Prot
  Sushi UniProtKB/Swiss-Prot
  V-set UniProtKB/Swiss-Prot
  Xlink UniProtKB/Swiss-Prot
PhenoGen Ncan PhenoGen
PRINTS LINKMODULE UniProtKB/Swiss-Prot
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  C_TYPE_LECTIN_1 UniProtKB/Swiss-Prot
  C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot
  EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  IG_LIKE UniProtKB/Swiss-Prot
  LINK_1 UniProtKB/Swiss-Prot
  LINK_2 UniProtKB/Swiss-Prot
  SUSHI UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000048036 RatGTEx
SMART CCP UniProtKB/Swiss-Prot
  CLECT UniProtKB/Swiss-Prot
  EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  LINK UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF48726 UniProtKB/Swiss-Prot
  SSF56436 UniProtKB/Swiss-Prot
  SSF57535 UniProtKB/Swiss-Prot
UniProt A6KA90 ENTREZGENE, UniProtKB/TrEMBL
  F1LNN7 ENTREZGENE
  G3V8R2 ENTREZGENE, UniProtKB/TrEMBL
  NCAN_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-04-17 Ncan  neurocan  LOC100911345  neurocan core protein-like  Data merged from RGD:6493516 737654 PROVISIONAL
2012-07-05 LOC100911345  neurocan core protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-22 Ncan  neurocan  Cspg3  chondroitin sulfate proteoglycan 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cspg3  chondroitin sulfate proteoglycan 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Cspg3  chondroitin sulfate proteoglycan 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain and displays developmental regulation 728116