Ralb (RAS like proto-oncogene B) - Rat Genome Database

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Gene: Ralb (RAS like proto-oncogene B) Rattus norvegicus
Analyze
Symbol: Ralb
Name: RAS like proto-oncogene B
RGD ID: 619852
Description: Predicted to enable GTPase activity; enzyme binding activity; and guanyl ribonucleotide binding activity. Involved in regulation of exocyst assembly and regulation of exocyst localization. Predicted to be located in midbody. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human RALB (RAS like proto-oncogene B); PARTICIPATES IN ceramide signaling pathway; pancreatic cancer pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dRalb; GTP binding protein; GTP binding protein); RALB Ras like proto-oncogene B; ras-related protein Ral-B; v-ral simian leukemia viral oncogene homolog B; v-ral simian leukemia viral oncogene homolog B (ras related); v-ral simian leukemia viral oncogene homolog B (ras related, GTP binding protein)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81333,140,834 - 33,176,997 (-)NCBIGRCr8
mRatBN7.21330,588,036 - 30,624,199 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1330,588,033 - 30,624,202 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1333,170,277 - 33,206,411 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01334,458,108 - 34,494,251 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01331,732,301 - 31,768,394 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01335,494,716 - 35,531,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1335,494,721 - 35,511,020 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01340,612,013 - 40,646,132 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41332,229,646 - 32,238,410 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11332,232,469 - 32,241,225 (-)NCBI
Celera1330,485,122 - 30,521,405 (-)NCBICelera
Cytogenetic Map13q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (ISO)
aconitine  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
ampicillin  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
captan  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
fenthion  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (ISO)
haloperidol  (EXP)
isoflurane  (ISO)
ivermectin  (ISO)
methimazole  (EXP)
metronidazole  (EXP)
microcystin-LR  (ISO)
N-nitrosodimethylamine  (EXP)
neomycin  (EXP)
nickel sulfate  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenol red  (ISO)
PhIP  (EXP)
propiconazole  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (TAS)
midbody  (IEA,ISO,ISS)
plasma membrane  (IBA,IEA,ISO,ISS)

Molecular Function
ATPase binding  (IEA,ISO)
G protein activity  (IEA)
GDP binding  (IBA,IEA,ISO)
GTP binding  (IBA,IEA,ISO,ISS,NAS)
GTPase activity  (IBA,ISO,ISS)
protein binding  (ISO)
ubiquitin protein ligase binding  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. Lim KH, etal., Curr Biol. 2006 Dec 19;16(24):2385-94. doi: 10.1016/j.cub.2006.10.023.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. RalB mobilizes the exocyst to drive cell migration. Rosse C, etal., Mol Cell Biol. 2006 Jan;26(2):727-34.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Isolation of cDNA clones and tissue expression of rat ral A and ral B GTP-binding proteins. Wildey GM, etal., Biochem Biophys Res Commun 1993 Jul 15;194(1):552-9.
Additional References at PubMed
PMID:15489334   PMID:16330713   PMID:17202486   PMID:17875936   PMID:18756269   PMID:19166349   PMID:22393054   PMID:22871113   PMID:23376485   PMID:23533145   PMID:24056301  


Genomics

Comparative Map Data
Ralb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81333,140,834 - 33,176,997 (-)NCBIGRCr8
mRatBN7.21330,588,036 - 30,624,199 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1330,588,033 - 30,624,202 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1333,170,277 - 33,206,411 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01334,458,108 - 34,494,251 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01331,732,301 - 31,768,394 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01335,494,716 - 35,531,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1335,494,721 - 35,511,020 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01340,612,013 - 40,646,132 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41332,229,646 - 32,238,410 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11332,232,469 - 32,241,225 (-)NCBI
Celera1330,485,122 - 30,521,405 (-)NCBICelera
Cytogenetic Map13q11NCBI
RALB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382120,240,070 - 120,294,710 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2120,240,064 - 120,294,710 (+)EnsemblGRCh38hg38GRCh38
GRCh372121,010,428 - 121,052,286 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362120,726,884 - 120,768,756 (+)NCBINCBI36Build 36hg18NCBI36
Build 342120,726,643 - 120,768,515NCBI
Celera2114,337,260 - 114,379,139 (+)NCBICelera
Cytogenetic Map2q14.2ENTREZGENE
HuRef2113,334,200 - 113,376,091 (+)NCBIHuRef
CHM1_12121,014,820 - 121,056,700 (+)NCBICHM1_1
T2T-CHM13v2.02120,674,829 - 120,729,465 (+)NCBIT2T-CHM13v2.0
Ralb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391119,398,035 - 119,432,512 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1119,398,035 - 119,432,524 (-)EnsemblGRCm39 Ensembl
GRCm381119,470,305 - 119,504,782 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1119,470,305 - 119,504,794 (-)EnsemblGRCm38mm10GRCm38
MGSCv371121,366,882 - 121,401,359 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361121,297,855 - 121,332,174 (-)NCBIMGSCv36mm8
Celera1122,129,019 - 122,163,492 (-)NCBICelera
Cytogenetic Map1E2.3NCBI
cM Map152.29NCBI
Ralb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554599,531,538 - 9,574,766 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554599,533,081 - 9,574,464 (-)NCBIChiLan1.0ChiLan1.0
RALB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21322,254,513 - 22,296,579 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B22,269,488 - 22,311,548 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B7,185,192 - 7,227,220 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B120,760,879 - 120,802,697 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B120,748,123 - 120,802,698 (+)Ensemblpanpan1.1panPan2
RALB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11929,820,006 - 29,868,345 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1929,768,359 - 29,868,335 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1930,077,023 - 30,124,832 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01931,195,778 - 31,243,919 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1931,195,778 - 31,243,835 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11929,882,347 - 29,930,196 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01930,051,930 - 30,099,493 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01931,237,496 - 31,285,578 (-)NCBIUU_Cfam_GSD_1.0
Ralb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530391,338,266 - 91,379,916 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646950,236,409 - 50,279,583 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646950,237,804 - 50,279,483 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1531,064,355 - 31,122,621 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11531,064,341 - 31,118,437 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21536,646,622 - 36,696,923 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1109,999,828 - 10,041,158 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl109,999,904 - 10,016,473 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606112,647,588 - 12,689,047 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473224,803,311 - 24,821,038 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473224,804,794 - 24,841,744 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ralb
187 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:228
Count of miRNA genes:151
Interacting mature miRNAs:173
Transcripts:ENSRNOT00000003413
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134266636Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131176653532331607Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131176653532331607Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133039535141184251Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat

Markers in Region
RH128968  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21330,588,081 - 30,588,238 (+)MAPPERmRatBN7.2
Rnor_6.01335,494,765 - 35,494,921NCBIRnor6.0
Rnor_5.01340,612,057 - 40,612,213UniSTSRnor5.0
RGSC_v3.41332,229,690 - 32,229,846UniSTSRGSC3.4
Celera1330,485,166 - 30,485,322UniSTS
Cytogenetic Map13q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 38 26 15 26 1 2 67 35 41 11 1
Low 6 19 15 4 15 7 9 7 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003413   ⟹   ENSRNOP00000003413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1330,588,039 - 30,624,202 (-)Ensembl
Rnor_6.0 Ensembl1335,494,721 - 35,511,020 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096405   ⟹   ENSRNOP00000087562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1330,588,033 - 30,624,034 (-)Ensembl
RefSeq Acc Id: NM_053821   ⟹   NP_446273
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81333,140,836 - 33,176,997 (-)NCBI
mRatBN7.21330,588,038 - 30,624,199 (-)NCBI
Rnor_6.01335,494,721 - 35,531,485 (-)NCBI
Rnor_5.01340,612,013 - 40,646,132 (-)NCBI
RGSC_v3.41332,229,646 - 32,238,410 (-)RGD
Celera1330,485,122 - 30,521,405 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090267   ⟹   XP_038946195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81333,140,834 - 33,176,722 (-)NCBI
mRatBN7.21330,588,036 - 30,624,034 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_446273   ⟸   NM_053821
- UniProtKB: P36860 (UniProtKB/Swiss-Prot),   A6K7W8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003413   ⟸   ENSRNOT00000003413
RefSeq Acc Id: XP_038946195   ⟸   XM_039090267
- Peptide Label: isoform X1
- UniProtKB: P36860 (UniProtKB/Swiss-Prot),   A6K7W8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000087562   ⟸   ENSRNOT00000096405

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P36860-F1-model_v2 AlphaFold P36860 1-206 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619852 AgrOrtholog
BioCyc Gene G2FUF-18523 BioCyc
Ensembl Genes ENSRNOG00000002440 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055013141 UniProtKB/Swiss-Prot
  ENSRNOG00060005469 UniProtKB/Swiss-Prot
  ENSRNOG00065009578 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003413.7 UniProtKB/TrEMBL
  ENSRNOT00000096405.1 UniProtKB/Swiss-Prot
  ENSRNOT00055022511 UniProtKB/Swiss-Prot
  ENSRNOT00060009099 UniProtKB/Swiss-Prot
  ENSRNOT00065015348 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116546 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 116546 ENTREZGENE
PANTHER PTHR24070 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24070:SF199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ralb PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002440 RatGTEx
  ENSRNOG00055013141 RatGTEx
  ENSRNOG00060005469 RatGTEx
  ENSRNOG00065009578 RatGTEx
SMART RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6K7W8 ENTREZGENE, UniProtKB/TrEMBL
  F1LQ62_RAT UniProtKB/TrEMBL
  P36860 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-24 Ralb  RAS like proto-oncogene B  Ralb  RALB Ras like proto-oncogene B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-05-20 Ralb  RALB Ras like proto-oncogene B  Ralb  v-ral simian leukemia viral oncogene homolog B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-23 Ralb  v-ral simian leukemia viral oncogene homolog B  Ralb  v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Ralb  v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)  Ralb  v-ral simian leukemia viral oncogene homolog B (ras related)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Ralb  v-ral simian leukemia viral oncogene homolog B (ras related)  Ralb  v-ral simian leukemia viral oncogene homolog B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Ralb  v-ral simian leukemia viral oncogene homolog B      Symbol and Name updated 629477 APPROVED
2003-03-12 Ralb  v-ral simian leukemia viral oncogene homolog B  dRalb  v-ral simian leukemia viral oncogene homolog B (ras related)  Data merged from RGD:628783 628472 PROVISIONAL
2003-02-27 dRalb  v-ral simian leukemia viral oncogene homolog B (ras related)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Ralb  v-ral simian leukemia viral oncogene homolog B (ras related)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_transcript 2.3 kb transcript is detected 633818