Rpl8 (ribosomal protein L8) - Rat Genome Database

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Gene: Rpl8 (ribosomal protein L8) Rattus norvegicus
Analyze
Symbol: Rpl8
Name: ribosomal protein L8
RGD ID: 619827
Description: Enables 5.8S rRNA binding activity. Involved in cellular response to nerve growth factor stimulus. Part of cytosolic large ribosomal subunit. Orthologous to human RPL8 (ribosomal protein L8); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-nitrofluorene; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 60S ribosomal protein L8; large ribosomal subunit protein uL2; LOC108348142; MGC124745; MGC156485
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rpl8-ps7  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,506,815 - 110,509,106 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7110,506,800 - 110,509,103 (+)EnsemblGRCr8
GRCr8 Ensembl329,159,002 - 29,160,907 (+)EnsemblGRCr8
mRatBN7.27108,626,194 - 108,628,485 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,761,823 - 8,762,671 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl7108,622,324 - 108,628,482 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,816,101 - 11,816,944 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,399,316 - 20,400,159 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,654,637 - 18,655,480 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,967,608 - 117,969,886 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,507,224 - 118,509,256 (+)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl33,389,612 - 3,390,443 (+)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl7117,967,818 - 117,969,850 (+)Ensemblrn6Rnor6.0
Rnor_5.07118,499,676 - 118,501,954 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47114,954,061 - 114,956,339 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7104,975,054 - 104,977,332 (+)NCBICelera
RGSC_v3.17114,988,277 - 114,990,567 (+)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2-nitrofluorene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
azoxystrobin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
Brodifacoum  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diazinon  (ISO)
diethylstilbestrol  (EXP)
disodium selenite  (ISO)
doxorubicin  (ISO)
enniatin  (ISO)
enzyme inhibitor  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
furfural  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
haloperidol  (ISO)
ivermectin  (ISO)
maneb  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nitrates  (ISO)
nitric oxide  (ISO)
ochratoxin A  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (EXP)
picoxystrobin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
poly(propylene imine) macromolecule  (ISO)
pyrimidifen  (ISO)
pyrogallol  (ISO)
rotenone  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins. Angelastro JM, etal., BMC Neurosci. 2002;3:3. Epub 2002 Feb 28.
2. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Characterization by cDNA cloning of the mRNA of human ribosomal protein L8. Hanes J, etal., Biochem Biophys Res Commun 1993 Dec 30;197(3):1223-8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'. Tsurugi K, etal., J Biol Chem. 1977 Jun 10;252(11):3961-9.
11. Identification by affinity chromatography of the eukaryotic ribosomal proteins that bind to 5.8 S ribosomal ribonucleic acid. Ulbrich N, etal., J Biol Chem. 1979 Sep 10;254(17):8641-5.
Additional References at PubMed
PMID:1610349   PMID:12477932   PMID:12947022   PMID:12962325   PMID:16452087   PMID:16854843   PMID:19946888   PMID:21170055   PMID:21423176   PMID:22658674   PMID:22681889   PMID:23071613  
PMID:24625528   PMID:25957688   PMID:35352799  


Genomics

Comparative Map Data
Rpl8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,506,815 - 110,509,106 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7110,506,800 - 110,509,103 (+)EnsemblGRCr8
GRCr8 Ensembl329,159,002 - 29,160,907 (+)EnsemblGRCr8
mRatBN7.27108,626,194 - 108,628,485 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,761,823 - 8,762,671 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl7108,622,324 - 108,628,482 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,816,101 - 11,816,944 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,399,316 - 20,400,159 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0318,654,637 - 18,655,480 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,967,608 - 117,969,886 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,507,224 - 118,509,256 (+)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl33,389,612 - 3,390,443 (+)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl7117,967,818 - 117,969,850 (+)Ensemblrn6Rnor6.0
Rnor_5.07118,499,676 - 118,501,954 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47114,954,061 - 114,956,339 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7104,975,054 - 104,977,332 (+)NCBICelera
RGSC_v3.17114,988,277 - 114,990,567 (+)NCBI
Cytogenetic Map7q34NCBI
RPL8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,789,769 - 144,792,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,789,765 - 144,792,587 (-)Ensemblhg38GRCh38
GRCh378146,015,154 - 146,017,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,985,958 - 145,988,609 (-)NCBIBuild 36Build 36hg18NCBI36
Build 348145,985,958 - 145,988,533NCBI
Celera8142,192,658 - 142,195,309 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8141,130,731 - 141,133,382 (-)NCBIHuRef
CHM1_18146,053,730 - 146,056,381 (-)NCBICHM1_1
T2T-CHM13v2.08145,963,275 - 145,965,896 (-)NCBIT2T-CHM13v2.0
Rpl8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,788,271 - 76,790,518 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,788,278 - 76,790,514 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381576,904,071 - 76,906,318 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,904,078 - 76,906,314 (+)Ensemblmm10GRCm38
MGSCv371576,734,501 - 76,736,748 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361576,731,354 - 76,733,569 (+)NCBIMGSCv36mm8
Celera1578,399,102 - 78,401,349 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.28NCBI
Rpl8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,397,893 - 3,400,275 (+)Ensembl
ChiLan1.0NW_0049554543,397,893 - 3,400,275 (+)NCBIChiLan1.0ChiLan1.0
RPL8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27162,287,614 - 162,290,317 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18137,819,508 - 137,822,247 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,562,162 - 141,564,885 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18144,543,354 - 144,546,044 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8144,543,354 - 144,545,974 (-)EnsemblpanPan2panpan1.1
RPL8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11338,101,879 - 38,104,772 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1338,102,010 - 38,104,770 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1338,062,599 - 38,065,478 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01338,575,636 - 38,578,520 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,575,689 - 38,578,523 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11338,267,134 - 38,270,012 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01338,375,990 - 38,378,868 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,851,293 - 38,854,172 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rpl8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303112,736 - 115,171 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364707,537,448 - 7,541,388 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364707,538,835 - 7,541,192 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4136,107 - 138,652 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.14136,105 - 138,651 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24206,963 - 209,523 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPL8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,990,088 - 138,992,564 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,989,165 - 138,992,554 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666039849,024 - 851,588 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpl8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,087,009 - 12,093,204 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473512,090,624 - 12,093,127 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rpl8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11249,231,651 - 249,234,027 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rpl8
11 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:28
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000041984
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)792388565119280177Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
1331723Bw25Body weight QTL 253.348body mass (VT:0001259)body weight (CMO:0000012)796700404111672180Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)796700404118618702Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
25 1 36 136 93 81 45 85 45 18 299 167 11 99 62 85 36 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001034916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC101862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC126063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF111102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl329,159,960 - 29,160,833 (+)Ensembl
mRatBN7.2 Ensembl38,761,823 - 8,762,671 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000075451   ⟹   ENSRNOP00000064566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7118,507,224 - 118,509,256 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100252   ⟹   ENSRNOP00000077291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,622,324 - 108,628,481 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109113   ⟹   ENSRNOP00000080446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,622,324 - 108,628,482 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000156080   ⟹   ENSRNOP00000108728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl329,159,002 - 29,160,907 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000162746   ⟹   ENSRNOP00000104299
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7110,506,800 - 110,509,103 (+)Ensembl
RefSeq Acc Id: NM_001034916   ⟹   NP_001030088
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,506,815 - 110,509,106 (+)NCBI
mRatBN7.27108,626,194 - 108,628,485 (+)NCBI
Rnor_6.07117,967,608 - 117,969,886 (+)NCBI
Rnor_5.07118,499,676 - 118,501,954 (+)NCBI
RGSC_v3.47114,954,061 - 114,956,339 (+)RGD
Celera7104,975,054 - 104,977,332 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001030088 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI26064 (Get FASTA)   NCBI Sequence Viewer  
  EDM15929 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000077291.1
GenBank Protein P62919 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001030088   ⟸   NM_001034916
- UniProtKB: A0JMZ6 (UniProtKB/Swiss-Prot),   P62919 (UniProtKB/Swiss-Prot),   A6HSE3 (UniProtKB/TrEMBL),   A6HSE4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064566   ⟸   ENSRNOT00000075451
Ensembl Acc Id: ENSRNOP00000077291   ⟸   ENSRNOT00000100252
Ensembl Acc Id: ENSRNOP00000080446   ⟸   ENSRNOT00000109113
Ensembl Acc Id: ENSRNOP00000104299   ⟸   ENSRNOT00000162746
Ensembl Acc Id: ENSRNOP00000108728   ⟸   ENSRNOT00000156080
Protein Domains
Large ribosomal subunit protein uL2 C-terminal   Large ribosomal subunit protein uL2 RNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62919-F1-model_v2 AlphaFold P62919 1-257 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619827 AgrOrtholog
BioCyc Gene G2FUF-32897 BioCyc
Ensembl Genes ENSRNOG00000032635 Ensembl
  ENSRNOG00000048456 Ensembl
  ENSRNOG00000048523 Ensembl
  ENSRNOG00000068956 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000100252.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.30.30 UniProtKB/Swiss-Prot
  2.40.50.140 UniProtKB/Swiss-Prot
  4.10.950.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7307697 IMAGE-MGC_LOAD
InterPro NA-bd_OB-fold UniProtKB/Swiss-Prot
  Rbsml_prot_L2_RNA-bd_dom UniProtKB/Swiss-Prot
  Rib_L2_dom2 UniProtKB/Swiss-Prot
  Ribosomal_L2 UniProtKB/Swiss-Prot
  Ribosomal_L2_arc UniProtKB/Swiss-Prot
  Ribosomal_L2_C UniProtKB/Swiss-Prot
  Ribosomal_L2_CS UniProtKB/Swiss-Prot
  Ribosomal_L2_dom3 UniProtKB/Swiss-Prot
  Translation_prot_SH3-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:26962 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156485 IMAGE-MGC_LOAD
NCBI Gene 26962 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L8 UniProtKB/Swiss-Prot
  PTHR13691 UniProtKB/Swiss-Prot
Pfam Ribosomal_L2 UniProtKB/Swiss-Prot
  Ribosomal_L2_C UniProtKB/Swiss-Prot
PhenoGen Rpl8 PhenoGen
PIRSF Ribosomal_L2 UniProtKB/Swiss-Prot
PROSITE RIBOSOMAL_L2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000032635 RatGTEx
  ENSRNOG00000048456 RatGTEx
  ENSRNOG00000048523 RatGTEx
  ENSRNOG00000068956 RatGTEx
SMART Ribosomal_L2 UniProtKB/Swiss-Prot
  Ribosomal_L2_C UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50104 UniProtKB/Swiss-Prot
  SSF50249 UniProtKB/Swiss-Prot
UniProt A0ABK0L4F9_RAT UniProtKB/TrEMBL
  A0ABK0LAP8_RAT UniProtKB/TrEMBL
  A0JMZ6 ENTREZGENE
  A6HSE3 ENTREZGENE, UniProtKB/TrEMBL
  A6HSE4 ENTREZGENE, UniProtKB/TrEMBL
  P62919 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0JMZ6 UniProtKB/Swiss-Prot
  P25120 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Rpl8  ribosomal protein L8  LOC108348142  60S ribosomal protein L8  Data merged from RGD:11509187 737654 PROVISIONAL
2016-08-02 LOC108348142  60S ribosomal protein L8      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-26 Rpl8  ribosomal protein L8      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Rpl8  ribosomal protein L8      Symbol and Name status set to provisional 70820 PROVISIONAL