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Gene: Trpc1 (transient receptor potential cation channel, subfamily C, member 1) Rattus norvegicus

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Symbol:

Trpc1

Name:

transient receptor potential cation channel, subfamily C, member 1

RGD ID:

619783

Description:

Predicted to enable several functions, including ATPase binding activity; inositol 1,4,5 trisphosphate binding activity; and store-operated calcium channel activity. Involved in cellular response to hypoxia and modulation of chemical synaptic transmission. Is active in postsynaptic membrane and presynaptic membrane. Biomarker of type 2 diabetes mellitus. Orthologous to human TRPC1 (transient receptor potential cation channel subfamily C member 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; glutamate signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC100909709; short transient receptor potential channel 1; short transient receptor potential channel 1-like; transient receptor protein 1; TRP-1; Trrp1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	105,142,931 - 105,193,842 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	105,142,931 - 105,193,826 (-)	Ensembl				GRCr8
mRatBN7.2	8	96,263,322 - 96,314,220 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	96,263,329 - 96,314,276 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	101,935,007 - 101,979,557 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	100,134,262 - 100,178,810 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	97,973,204 - 98,017,754 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	103,503,982 - 103,554,905 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	103,503,985 - 103,554,468 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	102,953,764 - 102,954,177 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	8	102,955,430 - 103,005,377 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	100,770,833 - 100,821,420	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	95,710,876 - 95,759,508 (-)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiomegaly (ISO)

Diabetic Nephropathies (IEP)

Experimental Diabetes Mellitus (IEP)

Hyperalgesia (IMP)

Inflammation (ISO)

prostate cancer (ISO)

stomach cancer (ISO)

type 2 diabetes mellitus (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

amiloride (ISO)

amitrole (EXP)

arsenous acid (ISO)

atrazine (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

bisphenol F (EXP,ISO)

Butylbenzyl phthalate (EXP)

cadmium atom (EXP)

calcium atom (EXP,ISO)

calcium(0) (EXP,ISO)

carbachol (ISO)

chloroquine (EXP)

chlorpyrifos (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dicrotophos (ISO)

dioxygen (EXP,ISO)

doxorubicin (ISO)

fasudil (ISO)

fenvalerate (EXP)

flavonoids (EXP)

indometacin (ISO)

lead diacetate (EXP,ISO)

lead(0) (ISO)

malaoxon (EXP)

malathion (EXP)

metformin (ISO)

methamphetamine (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

Muscarine (ISO)

nickel atom (ISO)

ouabain (EXP)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenylephrine (EXP)

pyrethrins (EXP)

rotenone (ISO)

sildenafil citrate (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (ISO)

triptonide (ISO)

valproic acid (ISO)

Y-27632 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium ion transmembrane transport (IBA,IEA,ISO)

calcium ion transport (IEA)

cellular response to hypoxia (IEP)

melanin biosynthetic process (IEA,ISO)

modulation of chemical synaptic transmission (IDA,IMP)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

positive regulation of membrane hyperpolarization (ISO)

positive regulation of release of sequestered calcium ion into cytosol (IEA,ISO)

regulation of cytosolic calcium ion concentration (IBA,IEA,ISO)

relaxation of vascular associated smooth muscle (ISO)

response to calcium ion (IEA,ISO)

saliva secretion (ISO)

transmembrane transport (IEA)

Cellular Component

basolateral plasma membrane (ISO)

cation channel complex (IBA)

costamere (ISO)

cytoplasm (ISO)

membrane (IEA)

membrane raft (ISO)

plasma membrane (IBA,IEA,ISO)

postsynaptic membrane (IDA)

presynaptic membrane (IDA)

protein-containing complex (ISO)

receptor complex (IEA,ISO)

sarcomere (ISO)

Molecular Function

ATPase binding (IEA,ISO)

calcium channel activity (IEA)

inositol 1,4,5 trisphosphate binding (IBA,IEA,ISO)

metal ion binding (IEA)

monoatomic cation channel activity (ISO)

monoatomic ion channel activity (IEA)

protein binding (ISO)

signaling receptor binding (IEA,ISO)

store-operated calcium channel activity (IBA,IEA,ISO,ISS)

transmembrane transporter binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (IEA)

glutamate signaling pathway (IEA)

External Pathway Database Links

KEGG Pathway

Calcium signaling pathway

References

References - curated

#	Reference Title	Reference Citation
1.	TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization.	Alessandri-Haber N, etal., J Neurosci. 2009 May 13;29(19):6217-28. doi: 10.1523/JNEUROSCI.0893-09.2009.
2.	Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1.	Bergdahl A, etal., Circ Res 2003 Oct 31;93(9):839-47. Epub 2003 Oct 09.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Identification of a prognostic 5-Gene expression signature for gastric cancer.	Hou JY, etal., J Cancer Res Clin Oncol. 2017 Apr;143(4):619-629. doi: 10.1007/s00432-016-2324-z. Epub 2016 Dec 29.
6.	Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1.	Kim SJ, etal., Nature 2003 Nov 20;426(6964):285-91. Epub 2003 Nov 12.
7.	TRPC1 mediates slow excitatory synaptic transmission in hippocampal oriens/alveus interneurons.	Kougioumoutzakis A, etal., Mol Brain. 2020 Jan 29;13(1):12. doi: 10.1186/s13041-020-0558-9.
8.	Sildenafil inhibits chronically hypoxic upregulation of canonical transient receptor potential expression in rat pulmonary arterial smooth muscle.	Lu W, etal., Am J Physiol Cell Physiol. 2010 Jan;298(1):C114-23. doi: 10.1152/ajpcell.00629.2008. Epub 2009 Nov 4.
9.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
10.	Attenuation of store-operated Ca2+ entry and enhanced expression of TRPC channels in caudal artery smooth muscle from Type 2 diabetic Goto-Kakizaki rats.	Mita M, etal., Clin Exp Pharmacol Physiol. 2010 Jul;37(7):670-8. doi: 10.1111/j.1440-1681.2010.05373.x. Epub 2010 Mar 12.
11.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
12.	HNF4 alpha and the Ca-channel TRPC1 are novel disease candidate genes in diabetic nephropathy.	Niehof M and Borlak J, Diabetes. 2008 Apr;57(4):1069-77. Epub 2008 Jan 9.
13.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
14.	GOA pipeline	RGD automated data pipeline
15.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.	Zhu X, etal., Cell 1996 May 31;85(5):661-71.

Additional References at PubMed

PMID:8126111	PMID:10097141	PMID:10199829	PMID:11301024	PMID:14505576	PMID:15044151	PMID:15199065	PMID:15297455	PMID:15758179	PMID:15856275	PMID:16282360	PMID:16551274
PMID:16930403	PMID:17174323	PMID:17224452	PMID:17389736	PMID:17416589	PMID:17956991	PMID:18068335	PMID:18261457	PMID:18268005	PMID:18322138	PMID:18338793	PMID:18711860
PMID:18995841	PMID:19052258	PMID:19168436	PMID:19386284	PMID:19715666	PMID:20005206	PMID:20093626	PMID:20426773	PMID:20431989	PMID:20631248	PMID:21361857	PMID:22073358
PMID:22157757	PMID:22201561	PMID:22534489	PMID:22547346	PMID:23169006	PMID:23382219	PMID:23526217	PMID:23526219	PMID:23542055	PMID:23764169	PMID:23922735	PMID:24107839
PMID:24336649	PMID:24631674	PMID:25114176	PMID:25203114	PMID:25461595	PMID:25627107	PMID:25649357	PMID:25740156	PMID:25939574	PMID:26155749	PMID:26494622	PMID:27129253
PMID:27641617	PMID:28478801	PMID:28627661	PMID:28697491	PMID:29634917	PMID:31878108	PMID:31982426	PMID:33991460	PMID:34283935	PMID:37722585

Genomics

Comparative Map Data

Trpc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	105,142,931 - 105,193,842 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	105,142,931 - 105,193,826 (-)	Ensembl				GRCr8
mRatBN7.2	8	96,263,322 - 96,314,220 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	96,263,329 - 96,314,276 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	101,935,007 - 101,979,557 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	100,134,262 - 100,178,810 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	97,973,204 - 98,017,754 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	103,503,982 - 103,554,905 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	103,503,985 - 103,554,468 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	102,953,764 - 102,954,177 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	8	102,955,430 - 103,005,377 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	100,770,833 - 100,821,420	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	95,710,876 - 95,759,508 (-)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

TRPC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	142,724,034 - 142,807,888 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	142,724,034 - 142,807,888 (+)	Ensembl			hg38	GRCh38
GRCh37	3	142,442,876 - 142,526,730 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	143,925,956 - 144,009,420 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	143,925,963 - 144,009,427	NCBI
Celera	3	140,866,763 - 140,950,233 (+)	NCBI		Celera
Cytogenetic Map	3	q23	NCBI
HuRef	3	139,815,981 - 139,899,449 (+)	NCBI		HuRef
CHM1_1	3	142,406,259 - 142,489,727 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	145,471,273 - 145,555,131 (+)	NCBI		T2T-CHM13v2.0

Trpc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	95,587,125 - 95,632,438 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	95,587,135 - 95,632,428 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	95,705,072 - 95,750,386 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	95,705,082 - 95,750,375 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	95,607,046 - 95,650,777 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	95,515,979 - 95,559,710 (-)	NCBI		MGSCv36	mm8
Celera	9	95,273,759 - 95,317,486 (-)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	50.2	NCBI

Trpc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955508	3,143,868 - 3,211,613 (-)	Ensembl
ChiLan1.0	NW_004955508	3,143,868 - 3,211,613 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRPC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	140,634,964 - 140,718,579 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	140,639,696 - 140,726,837 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	139,757,408 - 139,841,006 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	147,348,776 - 147,432,332 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	147,349,056 - 147,432,332 (+)	Ensembl			panPan2	panpan1.1

TRPC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	38,350,066 - 38,416,086 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	38,350,278 - 38,414,464 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	38,276,236 - 38,342,159 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	38,882,222 - 38,948,154 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	38,882,141 - 38,948,153 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	38,564,280 - 38,643,474 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	38,640,845 - 38,706,480 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	38,884,935 - 38,950,859 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Trpc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	77,600,930 - 77,678,903 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936540	4,323,528 - 4,418,685 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936540	4,340,672 - 4,417,655 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRPC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	83,436,395 - 83,498,478 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	83,436,343 - 83,498,419 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	91,200,922 - 91,271,298 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRPC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	47,827,295 - 47,909,207 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	47,827,247 - 47,909,202 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	20,761,507 - 20,843,909 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trpc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	19,307,346 - 19,375,537 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Trpc1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	87,162,586 - 87,206,195 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Trpc1
539 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	350
Count of miRNA genes:	219
Interacting mature miRNAs:	244
Transcripts:	ENSRNOT00000013144
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879878	Bw183	Body weight QTL 183		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	62848139	107848139	Rat
1300177	Cm2	Cardiac mass QTL 2	3.65		heart mass (VT:0007028)	heart weight (CMO:0000017)	8	63141536	109261840	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
12879879	Cm99	Cardiac mass QTL 99		0.001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	62848139	107848139	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	62970527	107970527	Rat
12879880	Cm100	Cardiac mass QTL 100		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	62848139	107848139	Rat
12879881	Cm101	Cardiac mass QTL 101		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	8	62848139	107848139	Rat
12879882	Am8	Aortic mass QTL 8		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	62848139	107848139	Rat
12879883	Kidm65	Kidney mass QTL 65		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	62848139	107848139	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
71120	Niddm21	Non-insulin dependent diabetes mellitus QTL 21	3.73		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	8	66992095	111992095	Rat
8693654	Alc32	Alcohol consumption QTL 32	2	0.755	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	8	97492344	116428905	Rat
1358912	Bw51	Body weight QTL 51	2.95		body mass (VT:0001259)	body weight (CMO:0000012)	8	60248093	105248093	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
2293697	Bmd39	Bone mineral density QTL 39			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	8	62848139	107848139	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	63404444	108404444	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	35464071	107982864	Rat
1331837	Bw23	Body weight QTL 23	4.19	0.00007	body mass (VT:0001259)	body weight (CMO:0000012)	8	55428416	107963099	Rat
1331838	Niddm61	Non-insulin dependent diabetes mellitus QTL 61	3.53	0.0004	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	62963099	107963099	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1331769	Rf39	Renal function QTL 39	3.871		urine output (VT:0003620)	timed urine volume (CMO:0000260)	8	50763951	107970527	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	35464071	107982864	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	39106363	114525825	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
10402857	Bp380	Blood pressure QTL 380		0.95	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	35464071	107982864	Rat
2301402	Bp316	Blood pressure QTL 316		0.005	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	62848139	107848139	Rat
631664	Hcar3	Hepatocarcinoma resistance QTL 3	2.9	0.0005	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	8	62982864	107982864	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

RH134083

Rat Assembly	Chr	Position (strand)	Source
Celera	8	95,710,939 - 95,711,135	UniSTS
RH 3.4 Map	8	1051.8	UniSTS
Cytogenetic Map	8	q31	UniSTS

RH144273

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	96,264,527 - 96,264,709 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	103,505,187 - 103,505,368	NCBI	Rnor6.0
Rnor_5.0	8	102,956,183 - 102,956,364	UniSTS	Rnor5.0
RGSC_v3.4	8	100,771,586 - 100,771,767	UniSTS	RGSC3.4
Celera	8	95,712,080 - 95,712,261	UniSTS
RH 3.4 Map	8	1053.4	UniSTS
Cytogenetic Map	8	q31	UniSTS

UniSTS:236220

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	96,264,695 - 96,264,914 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	103,505,355 - 103,505,573	NCBI	Rnor6.0
Rnor_5.0	8	102,956,351 - 102,956,569	UniSTS	Rnor5.0
RGSC_v3.4	8	100,771,754 - 100,771,972	UniSTS	RGSC3.4
Celera	8	95,712,248 - 95,712,466	UniSTS
Cytogenetic Map	8	q31	UniSTS

Trpc1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	96,265,043 - 96,265,153 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	103,505,703 - 103,505,812	NCBI	Rnor6.0
Rnor_5.0	8	102,956,699 - 102,956,808	UniSTS	Rnor5.0
Celera	8	95,712,596 - 95,712,705	UniSTS
Cytogenetic Map	8	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	84	59	6	348	184	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001413355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_053558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766571	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF061266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF061873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ839447	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000079965 ⟹ ENSRNOP00000072139

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	105,142,931 - 105,193,826 (-)	Ensembl
mRatBN7.2 Ensembl	8	96,263,329 - 96,314,276 (-)	Ensembl
Rnor_6.0 Ensembl	8	103,503,985 - 103,554,399 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000089833 ⟹ ENSRNOP00000074229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	105,142,931 - 105,193,826 (-)	Ensembl
mRatBN7.2 Ensembl	8	96,263,329 - 96,313,725 (-)	Ensembl
Rnor_6.0 Ensembl	8	103,503,988 - 103,554,468 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000140677 ⟹ ENSRNOP00000106898

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	105,143,832 - 105,193,826 (-)	Ensembl

RefSeq Acc Id:

NM_001413355 ⟹ NP_001400284

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,931 - 105,193,826 (-)	NCBI
mRatBN7.2	8	96,263,322 - 96,314,220 (-)	NCBI

RefSeq Acc Id:

NM_053558 ⟹ NP_446010

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,931 - 105,193,826 (-)	NCBI
mRatBN7.2	8	96,263,322 - 96,314,220 (-)	NCBI
Rnor_6.0	8	103,503,982 - 103,554,381 (-)	NCBI
Rnor_5.0	8	102,953,764 - 102,954,177 (-)	NCBI
Rnor_5.0	8	102,955,430 - 103,005,377 (-)	NCBI
RGSC_v3.4	8	100,770,833 - 100,821,420 (-)	RGD
Celera	8	95,710,876 - 95,759,508 (-)	RGD

Sequence:

show sequence

CTGCCCCCGTCCTGGGCCGCGATGATGGCGGCCCTGTACCCGAGCACGGACCTCTCTGGCGTCT
CCTCCTCCTCCCTGCCTTCCTCCCCATCCTCCTCATCGCCCAACGAAGTGATGGCGCTGAAGGA
TGTGCGAGAGGTGAAGGAGGAGAACACCTTGAATGAGAAGCTTTTCTTGCTGGCGTGCGACAAG
GGTGACTATTATATGGTTAAAAAGATTTTGGAGGAAAACAGTTCAGGTGACTTGAACATAAATT
GCGTAGATGTGCTTGGGAGAAATGCTGTTACCATAACTATTGAAAACGAAAGCTTGGATATACT
GCAGCTGCTTTTGGACTACGGTTGTCAGAAACTTATGGAACGAATTCAGAATCCGGAATACTCA
ACAACAATGGATGTTGCACCAGTTATTTTAGCTGCTCATCGTAACAACTATGAGATCCTCACAA
TGCTTCTGAAGCAGGACGTGGCTTTGCCCAAGCCCCATGCTGTTGGCTGTGAATGCACGCTGTG
TTCTGCGAAAAACAAAAAGGACAGCCTCAGACATTCCAGGTTTCGTCTTGATATCTATAGATGT
CTGGCCAGTCCAGCTCTAATAATGTTAACAGAGGAGGATCCAATTCTGAGAGCGTTTGAACTTA
GTGCTGACTTAAAGGAACTCAGCCTTGTGGAGGTGGAATTCTGGAATGACTATGAAGAGCTAGC
CCGTCAGTGCAAAATGTTTGCTAAAGATTTGCTTGCGCAAGCTCGGAATTCTCGTGAACTGGAA
GTTATCCTAAACCATACATCTAGTGATGAGCCTCTTGACAAACGAGGACTACTAGAAGAAAGAA
TGAATTTAAGTCGTCTGAAACTTGCTATCAAATATAACCAGAAGGAGTTTGTCTCCCAGTCAAA
TTGCCAGCAGTTCCTGAACACCGTTTGGTTCGGACAGATGTCAGGTTACCGCCGTAAGCCCACC
TGTAAGAAGATAATGACTGTTTTGACAGTTGGCATTTTCTGGCCAGTTCTGTCACTGTGTTACT
TGATAGCTCCCAAATCTCAATTCGGCAGAATCATTCACACACCGTTCATGAAGTTTATTATTCA
TGGAGCTTCATATTTCACATTCTTGCTGTTACTCAATCTCTACTCACTTGTCTACAATGAGGAC
AAGAAAAATACAATGGGGCCAGCCCTTGAGAGAATAGACTACCTTCTCATACTGTGGATTATTG
GGATGATTTGGTCAGACATTAAGAGGCTGTGGTATGAAGGGTTGGAAGACTTCTTAGAAGAATC
TCGTAACCAGCTCAGCTTTGTTATGAATTCCCTTTACTTGGCAACTTTTGCCCTCAAAGTGGTG
GCTCACAACAAGTTTCATGATTTTGCCGACCGGAAGGACTGGGATGCGTTCCACCCCACACTGG
TAGCAGAAGGGCTTTTCGCCTTTGCAAACGTTCTGAGTTACCTTCGGCTCTTCTTTATGTACAC
AACCAGCTCTATTTTGGGCCCACTGCAGATTTCAATGGGACAGATGTTACAAGATTTTGGGAAA
TTTCTAGGAATGTTCCTTCTTGTTCTGTTTTCCTTCACGATTGGACTGACACAGCTCTATGACA
AAGGGTACACTTCCAAAGAGCAGAAGGACTGCGTAGGCATCTTCTGTGAACAGCAAAGCAACGA
CACCTTCCACTCGTTCATTGGCACCTGCTTTGCTCTGTTCTGGTACATCTTCTCCTTAGCGCAT
GTGGCCATCTTTGTCACCAGGTTTAGCTATGGGGAAGAACTGCAGTCCTTCGTTGGGGCTGTGA
TTGTCGGAACTTACAATGTCGTGGTTGTGATCGTGCTTACAAAGCTACTGGTAGCGATGCTTCA
TAAGAGCTTCCAGCTGATAGCAAATCATGAGGATAAAGAATGGAAGTTTGCTCGAGCGAAGCTA
TGGCTCAGCTACTTTGATGACAAATGCACACTGCCCCCACCTTTCAACATCATTCCTTCTCCGA
AGACTATCTGCTATATGATCAGCAGCCTCAGCAAGTGGGTGTGCTCGCACACCTCCAAAGGCAA
GGTCAGACGGCAGAACAGCTTGAAGGAGTGGAGAAACTTAAAACAAAAGAGAGATGAGAACTAC
CAGAAGGTGATGTGCTGCCTAGTGCATCGATACCTGACCTCCATGCGACAGAAGATGCAGAGCA
CAGACCAAGCCACCGTGGAGAATCTCAATGAACTGCGCCAAGATCTGTCAAAATTCCGAAATGA
AATAAGGGATTTGCTTGGCTTTCGGACTTCTAAATATGCTATGTTTTATCCCAAAAATTAGCCA
TTTTCTAAATCTTGTAGAAATAATTTTCTTTAATAAATCTGAAAGACTGTATTTGCATACCTTT
CAATTAAATCAATAAGATATATATGGGCATAAACAATTACACAGAAGCCATTCTTTAAATATTT
ATAGCATAAACATATGTTGTGTAAATATGTATATAGAGCTAGTTTTTTAAAACCTGTCTGTGAC
TTTTTGTAGAAGCAAAACCATTTTGTTAGCATGCTACTTTGTTTTCTTAGTTGGTCAGTGCTTA
CATTCGACGTGTGTAAGAGGGGCAGCTCTCAGTGTACGCATGGCCCACTCCATTTATACGCGAA
GATCAGCAAACGCGGCTACCTTAAGACACACTTGAAGAGCTCATGCTGTTGAAATCTCTTGTTT
TAGGAGTTCACACAGAGTTCAGTATATATTGTTTAGGAGTTTAGCTTCATCTAAAATACCCTAC
TTTTTCTTTTGTTAGAATCTTAAGCAGCAGAGAAAAGTTTATAATAAATATTTGAATTTAACCC
AGTCATGGTGATGAATGCCTTTAATCCCAGCACTCGGGAGGCAGAGGCAGGCAGATCTCTGAGT
TCAAGGTCAGCCTGGTCTACAGAGTGGGTTCCAGGATAGCCCCGGCTACACAGAGAAACCCTGT
CTTGGAAAAATAAAAAACAACAAAAAAAAATTTAAATTATTTATTTATGTCTATCTAAATTCAC
GTTGGTATTTGTTGTGTAGTATATTTACTTTTACATGGTTATAATTTATATTTTTAATTTTGTT
TTGACATAACATTATTTTATATATATTTCCCTATATTAAGGTAGTTTATATGTTTAAATATTTA
TAGACGTCTGTGAATTTTGAAAAATAGTAGCCATCTTTTACCCATAGAATACTTGTTTCTATTT
ATACCCTCGCAGAGGTACCTCTTAAGCATTTGGCTAAGTTTAGCTTTTCCTTCCAATTTTTCAA
GTTGGAGTAAAACTCATCGTTACAAAGTAGAAGCTGCTTATCTTCATGTGCGGTCACAGTGGGC
TTGGCCGGAGAGCACTGGGCCTTGCTTGCAGAAGGCTGCTTTCCGTTCACTCCAAGGCTCTTGA
GCTCCTCTTCCAAAGTTTCTCCCACAGAGCCTACCACAGCTTCTACAAAACTGGCCTCGTGCTT
GCGGCTTGAGATGTAAAGCATTGTTTATTCAATTTGAAAATAAAAAGAATTTGACTGCTTTTCA
GTGTTCATGTAAAGGTGGAGCTGAAGGTTTCCCCAGCTATGGCACAGACATTCCTGCAGCACGT
TTGGTGAGAAATTACCTTCGGAACTGAACGTCAGCTGGCATTGAGGCCACAGAGTGCAGACAGC
CCTGGTCTGTGAGCGCCGCCCACCCCGGGGCAGCTGAAGATCCCAGTGTAGGTTTCATCTTGCT
TTTTGCATTTGTTTTTAATGTCCCAGGTTTAAGTGTTCCCTCTTTTGGGCAAATTCTTATAAAA
ATGTTTATTGTAAAATTATATATTTTGTCTACAATGGGATTATGCGCTTCCAAGTTGATATTTT
ACATCAGGATTTTTAGTCATTCTAAAAAAAATACCTAATTATTAAAAAATTTATAGAGTACCTA
TGTGTGCATGAATTACTGACGAGGTATATTTTGAATGACAGCATATTGTAAGAAAAGAGTGAAT
AAAATTTGGCATTAGATTATAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039082218 ⟹ XP_038938146

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,933 - 105,193,309 (-)	NCBI
mRatBN7.2	8	96,263,322 - 96,313,705 (-)	NCBI

RefSeq Acc Id:

XM_039082219 ⟹ XP_038938147

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,933 - 105,179,304 (-)	NCBI
mRatBN7.2	8	96,263,322 - 96,300,720 (-)	NCBI

RefSeq Acc Id:

XM_039082220 ⟹ XP_038938148

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,933 - 105,193,842 (-)	NCBI
mRatBN7.2	8	96,263,322 - 96,313,705 (-)	NCBI

RefSeq Acc Id:

XM_063266253 ⟹ XP_063122323

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,933 - 105,193,842 (-)	NCBI

RefSeq Acc Id:

XM_063266254 ⟹ XP_063122324

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,933 - 105,193,842 (-)	NCBI

RefSeq Acc Id:

XM_063266255 ⟹ XP_063122325

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	105,142,933 - 105,193,841 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001400284	(Get FASTA)	NCBI Sequence Viewer
	NP_001416183	(Get FASTA)	NCBI Sequence Viewer
	NP_446010	(Get FASTA)	NCBI Sequence Viewer
	XP_038938146	(Get FASTA)	NCBI Sequence Viewer
	XP_038938147	(Get FASTA)	NCBI Sequence Viewer
	XP_038938148	(Get FASTA)	NCBI Sequence Viewer
	XP_063122323	(Get FASTA)	NCBI Sequence Viewer
	XP_063122324	(Get FASTA)	NCBI Sequence Viewer
	XP_063122325	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC16725	(Get FASTA)	NCBI Sequence Viewer
	AAC67387	(Get FASTA)	NCBI Sequence Viewer
	ABH07673	(Get FASTA)	NCBI Sequence Viewer
	EDL77512	(Get FASTA)	NCBI Sequence Viewer
	EDL77514	(Get FASTA)	NCBI Sequence Viewer
	EDL77515	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072139
	ENSRNOP00000074229
GenBank Protein	Q9QX01	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_446010 ⟸ NM_053558
- Peptide Label:	isoform 2
- UniProtKB:	Q9QX01 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MMAALYPSTDLSGVSSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVK KILEENSSGDLNINCVDVLGRNAVTITIENESLDILQLLLDYGCQKLMERIQNPEYSTTMDVAP VILAAHRNNYEILTMLLKQDVALPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALI MLTEEDPILRAFELSADLKELSLVEVEFWNDYEELARQCKMFAKDLLAQARNSRELEVILNHTS SDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTV LTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGP ALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHD FADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLL VLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTR FSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDD KCTLPPPFNIIPSPKTICYMISSLSKWVCSHTSKGKVRRQNSLKEWRNLKQKRDENYQKVMCCL VHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPKN hide sequence

Ensembl Acc Id:

ENSRNOP00000072139 ⟸ ENSRNOT00000079965

Ensembl Acc Id:

ENSRNOP00000074229 ⟸ ENSRNOT00000089833

RefSeq Acc Id:	XP_038938148 ⟸ XM_039082220
- Peptide Label:	isoform X5
- UniProtKB:	Q9QX01 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038938146 ⟸ XM_039082218
- Peptide Label:	isoform X3
- UniProtKB:	Q0PG39 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038938147 ⟸ XM_039082219
- Peptide Label:	isoform X4
- UniProtKB:	Q9QX01 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	NP_001400284 ⟸ NM_001413355
- Peptide Label:	isoform 1
- UniProtKB:	Q0PG39 (UniProtKB/TrEMBL), A0A0G2K7J3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122324 ⟸ XM_063266254
- Peptide Label:	isoform X2
- UniProtKB:	Q9QX01 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063122323 ⟸ XM_063266253
- Peptide Label:	isoform X1
- UniProtKB:	Q0PG39 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122325 ⟸ XM_063266255
- Peptide Label:	isoform X6

Ensembl Acc Id:

ENSRNOP00000106898 ⟸ ENSRNOT00000140677

Protein Domains

Transient receptor ion channel

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9QX01-F1-model_v2	AlphaFold	Q9QX01	1-759	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619783	AgrOrtholog
BioCyc Gene	G2FUF-29478	BioCyc
Ensembl Genes	ENSRNOG00000054902	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000079965	ENTREZGENE
	ENSRNOT00000089833	ENTREZGENE
Gene3D-CATH	1.25.40.20	UniProtKB/Swiss-Prot
InterPro	Ankyrin_rpt	UniProtKB/Swiss-Prot
	Ankyrin_rpt-contain_sf	UniProtKB/Swiss-Prot
	Ion_trans_dom	UniProtKB/Swiss-Prot
	TRP_dom	UniProtKB/Swiss-Prot
	TRPC1_channel	UniProtKB/Swiss-Prot
	TRPC_channel	UniProtKB/Swiss-Prot
KEGG Report	rno:89821	UniProtKB/Swiss-Prot
NCBI Gene	89821	ENTREZGENE
PANTHER	PTHR10117	UniProtKB/Swiss-Prot
	PTHR10117:SF56	UniProtKB/Swiss-Prot
Pfam	Ank_2	UniProtKB/Swiss-Prot
	Ion_trans	UniProtKB/Swiss-Prot
	TRP_2	UniProtKB/Swiss-Prot
PhenoGen	Trpc1	PhenoGen
PRINTS	TRNSRECEPTRP	UniProtKB/Swiss-Prot
	TRPCHANNEL1	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000054902	RatGTEx
SMART	ANK	UniProtKB/Swiss-Prot
	TRP_2	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48403	UniProtKB/Swiss-Prot
UniProt	A0A0G2K7J3	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L971_RAT	UniProtKB/TrEMBL
	A6I264	ENTREZGENE, UniProtKB/TrEMBL
	F1LRB9_RAT	UniProtKB/TrEMBL
	Q0PG39	ENTREZGENE, UniProtKB/TrEMBL
	Q9QX01	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Trpc1	transient receptor potential cation channel, subfamily C, member 1	LOC100909709	short transient receptor potential channel 1-like	Data merged from RGD:6502512	737654	PROVISIONAL
2012-07-05	LOC100909709	short transient receptor potential channel 1-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-20	Trpc1	transient receptor potential cation channel, subfamily C, member 1	Trrp1	transient receptor protein 1	Symbol and Name updated	1299863	APPROVED
2002-08-07	Trrp1	transient receptor protein 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localizes to caveolae	1304442

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

External Pathway Database Links

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

External Pathway Database Links

External Pathway Database Links