Chkb (choline kinase beta) - Rat Genome Database

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Gene: Chkb (choline kinase beta) Rattus norvegicus
Analyze
Symbol: Chkb
Name: choline kinase beta
RGD ID: 61826
Description: Enables choline kinase activity. Predicted to be involved in CDP-choline pathway and phosphatidylethanolamine biosynthetic process. Predicted to act upstream of or within muscle organ development and phosphatidylcholine biosynthetic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (choline kinase beta); PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Chetk; Chkl; choline kinase-like; choline/ethanolamine kinase; choline/ethanolamine kinase beta; CK; CKB; CKEKB; EK; ethanolamine kinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,380,592 - 122,385,102 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7122,380,594 - 122,383,949 (-)EnsemblGRCr8
mRatBN7.27120,500,960 - 120,504,359 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,500,984 - 120,504,461 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7122,252,940 - 122,256,295 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,479,088 - 124,482,443 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,441,149 - 124,444,504 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,404,818 - 130,408,813 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,404,832 - 130,408,187 (-)Ensemblrn6Rnor6.0
Rnor_5.07130,089,639 - 130,093,008 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,746,749 - 127,750,104 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,973,588 - 116,976,943 (-)NCBICelera
RGSC_v3.17127,780,978 - 127,784,334 (-)NCBI
RH 3.4 Map7949.5RGD
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Complementary DNA sequence for a 42 kDa rat kidney choline/ethanolamine kinase. Aoyama C, etal., Biochim Biophys Acta 1998 Feb 5;1390(1):1-7.
2. Expression of brain-type creatine kinase and ubiquitous mitochondrial creatine kinase in the fetal rat brain: evidence for a nuclear energy shuttle. Chen L, etal., J Comp Neurol. 1995 Dec 18;363(3):389-401.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Complete purification of choline kinase from rat kidney and preparation of rabbit antibody against rat kidney choline kinase. Ishidate K, etal., J Biol Chem. 1984 Dec 10;259(23):14706-10.
5. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
6. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. A congenital muscular dystrophy with mitochondrial structural abnormalities caused by defective de novo phosphatidylcholine biosynthesis. Mitsuhashi S, etal., Am J Hum Genet. 2011 Jun 10;88(6):845-51.
9. Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy. Mitsuhashi S, etal., Hum Mol Genet. 2011 Oct 1;20(19):3841-51. Epub 2011 Jul 12.
10. Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Miyagawa T, etal., Nat Genet. 2008 Nov;40(11):1324-8. Epub 2008 Sep 28.
11. Polymorphism located between CPT1B and CHKB, and HLA-DRB1*1501-DQB1*0602 haplotype confer susceptibility to CNS hypersomnias (essential hypersomnia). Miyagawa T, etal., PLoS One. 2009;4(4):e5394. Epub 2009 Apr 30.
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
18. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:15489334   PMID:16371353   PMID:19915674   PMID:22871113  


Genomics

Comparative Map Data
Chkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,380,592 - 122,385,102 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7122,380,594 - 122,383,949 (-)EnsemblGRCr8
mRatBN7.27120,500,960 - 120,504,359 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,500,984 - 120,504,461 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7122,252,940 - 122,256,295 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,479,088 - 124,482,443 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,441,149 - 124,444,504 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,404,818 - 130,408,813 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,404,832 - 130,408,187 (-)Ensemblrn6Rnor6.0
Rnor_5.07130,089,639 - 130,093,008 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,746,749 - 127,750,104 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,973,588 - 116,976,943 (-)NCBICelera
RGSC_v3.17127,780,978 - 127,784,334 (-)NCBI
RH 3.4 Map7949.5RGD
Cytogenetic Map7q34NCBI
CHKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382250,578,963 - 50,582,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2250,578,959 - 50,601,455 (-)Ensemblhg38GRCh38
GRCh372251,017,392 - 51,021,278 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,364,253 - 49,368,260 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2234,893,420 - 34,897,461 (-)NCBICelera
Cytogenetic Map22q13.33NCBI
HuRef2233,908,386 - 33,912,427 (-)NCBIHuRef
CHM1_12250,976,120 - 50,980,161 (-)NCBICHM1_1
T2T-CHM13v2.02251,089,491 - 51,093,377 (-)NCBIT2T-CHM13v2.0
Chkb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,310,552 - 89,314,130 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1589,310,563 - 89,314,111 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381589,426,349 - 89,429,927 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,426,360 - 89,429,908 (-)Ensemblmm10GRCm38
MGSCv371589,256,798 - 89,260,330 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361589,254,134 - 89,257,666 (-)NCBIMGSCv36mm8
Celera1591,555,430 - 91,558,962 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.89NCBI
Chkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541333,588,600 - 33,591,758 (-)Ensembl
ChiLan1.0NW_00495541333,588,375 - 33,592,054 (-)NCBIChiLan1.0ChiLan1.0
CHKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22360,498,901 - 60,502,784 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12263,189,483 - 63,193,549 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,825,128 - 30,829,203 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,936,470 - 49,940,625 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,936,470 - 49,940,625 (-)EnsemblpanPan2panpan1.1
CHKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11016,733,071 - 16,736,797 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1016,733,095 - 16,736,758 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1016,710,701 - 16,714,430 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01017,459,391 - 17,463,120 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1017,459,328 - 17,463,931 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11017,183,779 - 17,187,508 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01017,506,808 - 17,510,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01017,638,970 - 17,642,699 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Chkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945242,891 - 246,731 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629243,095 - 247,093 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936629242,876 - 246,806 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5151,638 - 155,176 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.15151,638 - 155,176 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CHKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11933,055,296 - 33,059,442 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1933,055,294 - 33,059,230 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604592,282,539 - 92,286,806 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752187,956 - 191,137 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624752187,544 - 191,330 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Chkb
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11258,732,697 - 258,736,121 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Chkb
70 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:55
Count of miRNA genes:49
Interacting mature miRNAs:55
Transcripts:ENSRNOT00000015374
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7118556868125929417Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
AU046862  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,505,069 - 120,505,409 (+)MAPPERmRatBN7.2
Rnor_6.07130,408,928 - 130,409,265NCBIRnor6.0
Rnor_5.07130,093,749 - 130,094,086UniSTSRnor5.0
RGSC_v3.47127,750,845 - 127,751,182UniSTSRGSC3.4
Celera7116,977,684 - 116,978,021UniSTS
Cytogenetic Map7q34UniSTS
Chetk  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,501,074 - 120,501,250 (+)MAPPERmRatBN7.2
Rnor_6.07130,404,933 - 130,405,108NCBIRnor6.0
Rnor_5.07130,089,754 - 130,089,929UniSTSRnor5.0
RGSC_v3.47127,746,850 - 127,747,025UniSTSRGSC3.4
Celera7116,973,689 - 116,973,864UniSTS
RH 3.4 Map7949.5UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000015374   ⟹   ENSRNOP00000015374
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,380,594 - 122,383,949 (-)Ensembl
mRatBN7.2 Ensembl7120,500,984 - 120,504,461 (-)Ensembl
Rnor_6.0 Ensembl7130,404,832 - 130,408,187 (-)Ensembl
RefSeq Acc Id: NM_017177   ⟹   NP_058873
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,380,594 - 122,383,949 (-)NCBI
mRatBN7.27120,500,974 - 120,504,329 (-)NCBI
Rnor_6.07130,404,832 - 130,408,187 (-)NCBI
Rnor_5.07130,089,639 - 130,093,008 (-)NCBI
RGSC_v3.47127,746,749 - 127,750,104 (-)RGD
Celera7116,973,588 - 116,976,943 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242181   ⟹   XP_006242243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,380,592 - 122,385,102 (-)NCBI
mRatBN7.27120,500,964 - 120,504,359 (-)NCBI
Rnor_6.07130,404,818 - 130,408,813 (-)NCBI
Rnor_5.07130,089,639 - 130,093,008 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078574   ⟹   XP_038934502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,380,592 - 122,383,589 (-)NCBI
mRatBN7.27120,500,964 - 120,504,355 (-)NCBI
RefSeq Acc Id: XM_039078576   ⟹   XP_038934504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,380,592 - 122,383,236 (-)NCBI
mRatBN7.27120,500,960 - 120,503,708 (-)NCBI
RefSeq Acc Id: XR_010052945
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,381,839 - 122,385,102 (-)NCBI
RefSeq Acc Id: NP_058873   ⟸   NM_017177
- UniProtKB: O54783 (UniProtKB/Swiss-Prot),   A6K7M9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242243   ⟸   XM_006242181
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000015374   ⟸   ENSRNOT00000015374
RefSeq Acc Id: XP_038934504   ⟸   XM_039078576
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038934502   ⟸   XM_039078574
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54783-F1-model_v2 AlphaFold O54783 1-394 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695589
Promoter ID:EPDNEW_R6113
Type:initiation region
Name:Chkb_1
Description:choline kinase beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07130,408,208 - 130,408,268EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61826 AgrOrtholog
BioCyc Gene G2FUF-32434 BioCyc
BioCyc Pathway PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY3O-450 [phosphatidylcholine biosynthesis I] BioCyc
  PWY4FS-6 [phosphatidylethanolamine biosynthesis II] BioCyc
BioCyc Pathway Image PWY-7782 BioCyc
  PWY3O-450 BioCyc
  PWY4FS-6 BioCyc
Ensembl Genes ENSRNOG00000011404 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015374 ENTREZGENE
  ENSRNOT00000015374.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.1200.10 UniProtKB/Swiss-Prot
  Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5598184 IMAGE-MGC_LOAD
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:29367 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72507 IMAGE-MGC_LOAD
NCBI Gene 29367 ENTREZGENE
PANTHER CHOLINE/ETHANOALAMINE KINASE UniProtKB/Swiss-Prot
  PTHR22603:SF35 UniProtKB/Swiss-Prot
Pfam Choline_kinase UniProtKB/Swiss-Prot
PhenoGen Chkb PhenoGen
RatGTEx ENSRNOG00000011404 RatGTEx
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
TIGR TC204929
UniProt A6K7M8_RAT UniProtKB/TrEMBL
  A6K7M9 ENTREZGENE, UniProtKB/TrEMBL
  CHKB_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Chkb  choline kinase beta  Chetk  choline/ethanolamine kinase  Symbol and Name updated 1299863 APPROVED
2002-06-10 Chetk  choline/ethanolamine kinase      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in kidney 61550
gene_protein 394 amino acid predicted protein 61550