CHKB (choline kinase beta) - Rat Genome Database

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Gene: CHKB (choline kinase beta) Pan paniscus
Analyze
Symbol: CHKB
Name: choline kinase beta
RGD ID: 11725506
Description: ENCODES a protein that exhibits choline kinase activity (ortholog); INVOLVED IN CDP-choline pathway (inferred); muscle organ development (inferred); phosphatidylcholine biosynthetic process (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); chromosome 22q13 duplication syndrome (ortholog); congenital disorder of glycosylation Ig (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: choline/ethanolamine kinase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22360,498,901 - 60,502,784 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12263,189,483 - 63,193,549 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,825,128 - 30,829,203 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,936,470 - 49,940,625 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,936,470 - 49,940,625 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CHKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22360,498,901 - 60,502,784 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12263,189,483 - 63,193,549 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,825,128 - 30,829,203 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,936,470 - 49,940,625 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,936,470 - 49,940,625 (-)Ensemblpanpan1.1panPan2
CHKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382250,578,963 - 50,582,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2250,578,959 - 50,601,455 (-)EnsemblGRCh38hg38GRCh38
GRCh372251,017,392 - 51,021,278 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,364,253 - 49,368,260 (-)NCBINCBI36Build 36hg18NCBI36
Celera2234,893,420 - 34,897,461 (-)NCBICelera
Cytogenetic Map22q13.33NCBI
HuRef2233,908,386 - 33,912,427 (-)NCBIHuRef
CHM1_12250,976,120 - 50,980,161 (-)NCBICHM1_1
T2T-CHM13v2.02251,089,491 - 51,093,377 (-)NCBIT2T-CHM13v2.0
Gm44502
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,300,608 - 89,314,130 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1589,300,608 - 89,313,899 (-)EnsemblGRCm39 Ensembl
GRCm381589,416,405 - 89,429,927 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,416,405 - 89,429,696 (-)EnsemblGRCm38mm10GRCm38
MGSCv371589,246,836 - 89,260,127 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1591,545,496 - 91,558,759 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.89NCBI
Chkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,380,592 - 122,385,102 (-)NCBIGRCr8
mRatBN7.27120,500,960 - 120,504,359 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,500,984 - 120,504,461 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7122,252,940 - 122,256,295 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,479,088 - 124,482,443 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,441,149 - 124,444,504 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,404,818 - 130,408,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,404,832 - 130,408,187 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07130,089,639 - 130,093,008 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,746,749 - 127,750,104 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17127,780,978 - 127,784,334 (-)NCBI
Celera7116,973,588 - 116,976,943 (-)NCBICelera
RH 3.4 Map7949.5RGD
Cytogenetic Map7q34NCBI
Chkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541333,588,600 - 33,591,758 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541333,588,375 - 33,592,054 (-)NCBIChiLan1.0ChiLan1.0
CHKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11016,733,071 - 16,736,797 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1016,733,095 - 16,736,758 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1016,710,701 - 16,714,430 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01017,459,391 - 17,463,120 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1017,459,328 - 17,463,931 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11017,183,779 - 17,187,508 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01017,506,808 - 17,510,537 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01017,638,970 - 17,642,699 (+)NCBIUU_Cfam_GSD_1.0
Chkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945242,891 - 246,731 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629243,095 - 247,093 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936629242,876 - 246,806 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5151,638 - 155,176 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15151,638 - 155,176 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CHKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11933,055,296 - 33,059,442 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1933,055,294 - 33,059,230 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604592,282,539 - 92,286,806 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752187,956 - 191,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624752187,544 - 191,330 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000031544   ⟹   ENSPPAP00000008904
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2249,936,470 - 49,940,625 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000031550   ⟹   ENSPPAP00000008910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2249,936,689 - 49,940,290 (-)Ensembl
RefSeq Acc Id: XM_003804590   ⟹   XP_003804638
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22360,498,901 - 60,502,784 (-)NCBI
NHGRI_mPanPan12263,189,483 - 63,193,549 (-)NCBI
Mhudiblu_PPA_v02230,825,128 - 30,829,203 (-)NCBI
PanPan1.12249,936,470 - 49,940,625 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008961486   ⟹   XP_008959734
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22360,498,901 - 60,502,723 (-)NCBI
NHGRI_mPanPan12263,189,483 - 63,193,549 (-)NCBI
Mhudiblu_PPA_v02230,825,128 - 30,829,203 (-)NCBI
PanPan1.12249,936,470 - 49,940,625 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004668600
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22360,499,364 - 60,502,723 (-)NCBI
NHGRI_mPanPan12263,189,946 - 63,193,549 (-)NCBI
Mhudiblu_PPA_v02230,825,591 - 30,829,203 (-)NCBI
RefSeq Acc Id: XR_610263
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22360,499,137 - 60,502,723 (-)NCBI
NHGRI_mPanPan12263,189,718 - 63,193,549 (-)NCBI
Mhudiblu_PPA_v02230,825,361 - 30,829,203 (-)NCBI
PanPan1.12249,936,470 - 49,940,625 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003804638 (Get FASTA)   NCBI Sequence Viewer  
  XP_008959734 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008904
  ENSPPAP00000008904.1
  ENSPPAP00000008910.1
RefSeq Acc Id: XP_003804638   ⟸   XM_003804590
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZVB4 (UniProtKB/TrEMBL),   A0A2R8ZVC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008959734   ⟸   XM_008961486
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZVC1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000008910   ⟸   ENSPPAT00000031550
RefSeq Acc Id: ENSPPAP00000008904   ⟸   ENSPPAT00000031544


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027692 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000031544.1 UniProtKB/TrEMBL
  ENSPPAT00000031550.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1200.10 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100978500 UniProtKB/TrEMBL
NCBI Gene CHKB ENTREZGENE
PANTHER CHOLINE/ETHANOALAMINE KINASE UniProtKB/TrEMBL
  PTHR22603:SF35 UniProtKB/TrEMBL
Pfam Choline_kinase UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R8ZVB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZVC1 ENTREZGENE, UniProtKB/TrEMBL