Vipr1 (vasoactive intestinal peptide receptor 1) - Rat Genome Database

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Gene: Vipr1 (vasoactive intestinal peptide receptor 1) Rattus norvegicus
Analyze
Symbol: Vipr1
Name: vasoactive intestinal peptide receptor 1
RGD ID: 3961
Description: Enables vasoactive intestinal polypeptide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in achalasia. Orthologous to human VIPR1 (vasoactive intestinal peptide receptor 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC501076; MGC95067; PACAP type II receptor; PACAP-R-2; PACAP-R2; pituitary adenylate cyclase-activating polypeptide type II receptor; RATVASREC; RGD1564352; vasoactive intestinal polypeptide receptor; vasoactive intestinal polypeptide receptor 1; Vasopressive intestinal peptide receptor; VASREC; VIP-R-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,181,219 - 130,217,098 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8130,187,731 - 130,217,096 (+)EnsemblGRCr8
mRatBN7.28121,303,739 - 121,339,587 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,310,248 - 121,339,585 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8126,909,204 - 126,938,516 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08125,108,275 - 125,137,587 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08122,937,779 - 122,967,104 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,283,453 - 130,313,431 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08129,467,937 - 129,496,866 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera8120,444,918 - 120,474,479 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-nonylphenol  (ISO)
4-tert-Octylphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroacetaldehyde  (ISO)
chlorpyrifos  (EXP)
cidofovir anhydrous  (ISO)
copper(II) sulfate  (ISO)
cyclophosphamide  (EXP)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dichlorine  (EXP)
dioxygen  (ISO)
elemental selenium  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gallic acid  (ISO)
glafenine  (EXP)
glycidol  (EXP)
GW 4064  (ISO)
lipopolysaccharide  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nebivolol  (ISO)
nickel atom  (ISO)
nimesulide  (EXP)
orphenadrine  (EXP)
ozone  (EXP,ISO)
p-tert-Amylphenol  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-nitrosoglutathione  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triphenyl phosphate  (EXP)
troglitazone  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)
receptor complex  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Vasoactive intestinal peptide receptor-1 (VPAC-1) is a novel gene target of the hemolymphopoietic transcription factor Ikaros.PG - 13488-93 Dorsam G and Goetzl EJ, J Biol Chem 2002 Apr 19;277(16):13488-93.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Ishihara T, etal., Neuron 1992 Apr;8(4):811-9.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Age-dependent association of idiopathic achalasia with vasoactive intestinal peptide receptor 1 gene. Paladini F, etal., Neurogastroenterol Motil. 2009 Jun;21(6):597-602. Epub 2009 Feb 27.
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11. Anti-hyperglycemic, antioxidant and anti-inflammatory effects of VIP and a VPAC1 agonist on streptozotocin-induced diabetic mice. Yu R, etal., Peptides. 2011 Feb;32(2):216-22. Epub 2010 Dec 1.
12. Differential expression of vasoactive intestinal peptide receptor 1 expression in inflammatory bowel disease. Yukawa T, etal., Int J Mol Med. 2007 Aug;20(2):161-7.
Additional References at PubMed
PMID:8390245   PMID:8948424   PMID:12220728   PMID:12477932   PMID:15489334   PMID:15670850   PMID:18665096   PMID:20452385   PMID:23099490   PMID:23382219   PMID:23518767   PMID:24801739  
PMID:28776455   PMID:33098516   PMID:36430275  


Genomics

Comparative Map Data
Vipr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,181,219 - 130,217,098 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8130,187,731 - 130,217,096 (+)EnsemblGRCr8
mRatBN7.28121,303,739 - 121,339,587 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,310,248 - 121,339,585 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8126,909,204 - 126,938,516 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08125,108,275 - 125,137,587 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08122,937,779 - 122,967,104 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,283,453 - 130,313,431 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08129,467,937 - 129,496,866 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera8120,444,918 - 120,474,479 (+)NCBICelera
Cytogenetic Map8q32NCBI
VIPR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,489,299 - 42,537,568 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl342,489,299 - 42,537,688 (+)Ensemblhg38GRCh38
GRCh37342,530,791 - 42,579,060 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,519,121 - 42,554,064 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34342,519,120 - 42,554,064NCBI
Celera342,484,508 - 42,519,469 (+)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef342,574,992 - 42,623,180 (+)NCBIHuRef
CHM1_1342,481,967 - 42,530,261 (+)NCBICHM1_1
T2T-CHM13v2.0342,507,314 - 42,555,561 (+)NCBIT2T-CHM13v2.0
Vipr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,471,782 - 121,502,020 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9121,471,782 - 121,502,020 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389121,642,716 - 121,672,954 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,642,716 - 121,672,954 (+)Ensemblmm10GRCm38
MGSCv379121,551,834 - 121,582,072 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369121,491,414 - 121,519,332 (+)NCBIMGSCv36mm8
Celera9122,116,040 - 122,146,512 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.5NCBI
Vipr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542028,234,153 - 28,253,168 (-)Ensembl
ChiLan1.0NW_00495542028,234,590 - 28,253,146 (-)NCBIChiLan1.0ChiLan1.0
VIPR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2242,464,670 - 42,503,777 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1342,469,438 - 42,504,483 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0342,407,591 - 42,442,565 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1342,669,338 - 42,705,170 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl342,670,195 - 42,705,170 (+)EnsemblpanPan2panpan1.1
VIPR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12311,635,809 - 11,666,926 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2311,635,394 - 11,666,936 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2311,609,898 - 11,641,322 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02311,924,939 - 11,956,370 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2311,924,529 - 11,957,534 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12311,726,543 - 11,757,961 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02311,868,801 - 11,900,208 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02311,873,062 - 11,904,503 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Vipr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,208,554 - 200,255,619 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366952,564,890 - 2,607,676 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366952,564,917 - 2,597,009 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VIPR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1326,036,629 - 26,075,691 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11326,036,610 - 26,073,168 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21328,704,211 - 28,740,358 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VIPR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,950,129 - 3,984,849 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl223,950,193 - 3,984,948 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041163,214,473 - 163,249,573 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vipr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473077,128,649 - 77,153,750 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473077,128,547 - 77,155,531 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Vipr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18112,806,203 - 112,832,742 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:92
Count of miRNA genes:73
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000071573
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH129450  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27848,222 - 848,392 (+)MAPPERmRatBN7.2
mRatBN7.28121,339,344 - 121,339,526 (+)MAPPERmRatBN7.2
Rnor_6.08130,313,189 - 130,313,370NCBIRnor6.0
Rnor_6.072,837,279 - 2,837,448NCBIRnor6.0
Rnor_5.072,815,743 - 2,815,912UniSTSRnor5.0
Rnor_5.08129,496,624 - 129,496,805UniSTSRnor5.0
RGSC_v3.471,710,492 - 1,710,661UniSTSRGSC3.4
Celera7721,718 - 721,887UniSTS
Celera8120,474,237 - 120,474,418UniSTS
Cytogenetic Map7q11UniSTS
AV071699  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28121,339,425 - 121,339,514 (+)MAPPERmRatBN7.2
mRatBN7.27848,291 - 848,380 (+)MAPPERmRatBN7.2
Rnor_6.072,837,348 - 2,837,436NCBIRnor6.0
Rnor_6.08130,313,270 - 130,313,358NCBIRnor6.0
Rnor_5.072,815,812 - 2,815,900UniSTSRnor5.0
Rnor_5.08129,496,705 - 129,496,793UniSTSRnor5.0
RGSC_v3.471,710,561 - 1,710,649UniSTSRGSC3.4
Celera7721,787 - 721,875UniSTS
Celera8120,474,318 - 120,474,406UniSTS
Cytogenetic Map7q11UniSTS
MARC_17029-17030:1023294211:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera8120,462,069 - 120,462,546UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 46 67 126 95 11 39 24 32 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000071573   ⟹   ENSRNOP00000065438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8130,187,738 - 130,217,095 (+)Ensembl
mRatBN7.2 Ensembl8121,310,248 - 121,339,585 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097765   ⟹   ENSRNOP00000081668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8130,187,731 - 130,217,096 (+)Ensembl
RefSeq Acc Id: NM_012685   ⟹   NP_036817
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88130,187,761 - 130,217,098 (+)NCBI
mRatBN7.28121,310,248 - 121,339,587 (+)NCBI
Rnor_6.08130,283,453 - 130,313,431 (+)NCBI
Rnor_5.08129,467,937 - 129,496,866 (+)NCBI
Celera8120,444,918 - 120,474,479 (+)RGD
Sequence:
RefSeq Acc Id: XM_039080844   ⟹   XP_038936772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88130,181,222 - 130,217,098 (+)NCBI
mRatBN7.28121,303,741 - 121,339,587 (+)NCBI
RefSeq Acc Id: XM_039080845   ⟹   XP_038936773
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88130,181,219 - 130,217,098 (+)NCBI
mRatBN7.28121,303,739 - 121,339,587 (+)NCBI
RefSeq Acc Id: NP_036817   ⟸   NM_012685
- Peptide Label: precursor
- UniProtKB: P30083 (UniProtKB/Swiss-Prot),   A6I446 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038936773   ⟸   XM_039080845
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038936772   ⟸   XM_039080844
- Peptide Label: isoform X1
- UniProtKB: P30083 (UniProtKB/Swiss-Prot),   A6I446 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000065438   ⟸   ENSRNOT00000071573
Ensembl Acc Id: ENSRNOP00000081668   ⟸   ENSRNOT00000097765
Protein Domains
G-protein coupled receptors family 2 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R7K6-F1-model_v2 AlphaFold M0R7K6 1-459 view protein structure
AF-P30083-F1-model_v2 AlphaFold P30083 1-459 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3961 AgrOrtholog
BioCyc Gene G2FUF-28685 BioCyc
Ensembl Genes ENSRNOG00000047457 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000071573 ENTREZGENE
  ENSRNOT00000071573.3 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.1240.10 UniProtKB/Swiss-Prot
  Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7124910 IMAGE-MGC_LOAD
InterPro GPCR_2 UniProtKB/Swiss-Prot
  GPCR_2-like UniProtKB/Swiss-Prot
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot
  GPCR_2_secretin-like UniProtKB/Swiss-Prot
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot
  GPCR_2_VIP_rcpt UniProtKB/Swiss-Prot
  GPCR_2_VIP_rcpt_1 UniProtKB/Swiss-Prot
KEGG Report rno:24875 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95067 IMAGE-MGC_LOAD
NCBI Gene 24875 ENTREZGENE
PANTHER PDF RECEPTOR-LIKE PROTEIN-RELATED UniProtKB/Swiss-Prot
  VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1 UniProtKB/Swiss-Prot
Pfam 7tm_2 UniProtKB/Swiss-Prot
  HRM UniProtKB/Swiss-Prot
PhenoGen Vipr1 PhenoGen
PRINTS GPCRSECRETIN UniProtKB/Swiss-Prot
  VASOACTVEIPR UniProtKB/Swiss-Prot
  VIP1RECEPTOR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047457 RatGTEx
SMART HormR UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
  SSF111418 UniProtKB/Swiss-Prot
TIGR TC225321
UniProt A0A8I5ZT58_RAT UniProtKB/TrEMBL
  A6I446 ENTREZGENE, UniProtKB/TrEMBL
  M0R7K6_RAT UniProtKB/TrEMBL
  P30083 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-13 Vipr1  vasoactive intestinal peptide receptor 1  RGD1564352  vasoactive intestinal polypeptide receptor  Data merged from RGD:1564352 737654 APPROVED
2015-11-13 Vipr1  vasoactive intestinal peptide receptor 1  Vipr1  vasoactive intestinal peptide receptor 1  Type changed (type changed from [null] to [protein-coding]) 629549 APPROVED
2008-04-30 RGD1564352  vasoactive intestinal polypeptide receptor   RGD1564352_predicted  vasoactive intestinal polypeptide receptor (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564352_predicted  vasoactive intestinal polypeptide receptor (predicted)  LOC501076  vasoactive intestinal polypeptide receptor  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501076  vasoactive intestinal polypeptide receptor      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Vipr1  Vasopressive intestinal peptide receptor      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains promoter region contains a 32 GGGA Ikaros core binding element 625520
gene_expression expressed in many tissues 625520
gene_expression mRNA expressed highly in brain neurons, especially in the cerebral cortex and hippocampus 727528
gene_function a G-protein-coupled receptor for vasoactive intestinal peptide (VIP) 625520
gene_protein predicted protein consists of 459 aa residues and masses 52 kDa 727528